Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Logo MUG-Forschungsportal

Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid Stoffw Microb

Cadamuro, J; Decho, C; Frans, G; Auer, S; von, Meyer, A; Kniewallner, KM; Drerup, M; Heinrich, E; Keppel, MH; Mrazek, C; Felder, TK; Oberkofler, H; Haschke-Becher, E; Kipman, U; Salek, T; Vermeersh, P, , European, Federation, of, Clinical, Chemistry, and, Laboratory, Medicine, (EFLM), Working, Group, “Preanalytical, Phase”, (WG-PRE).
Acidification of 24-hour urine in urolithiasis risk testing: An obsolete relic?
Clin Chim Acta. 2022; 532: 1-9. Doi: 10.1016/j.cca.2022.05.010
Web of Science PubMed FullText FullText_MUG


Co-Autor*innen der Med Uni Graz
Keppel Martin

Dimensions Citations:

Plum Analytics:

Scite (citation analytics):

BACKGROUND: Recommendations on the optimal preservation of 24 h urine for the metabolic work-up in urolithiasis patients are very heterogeneous. In case two such tests with different storage condition recommendations are being analysed, multiple collections would be needed, challenging especially elderly and very young patients. We therefore aimed to evaluate the stability of urine constituents under different storage conditions. MATERIAL AND METHODS: We collected urine samples from ten healthy volunteers and prepared aliquots to be stored either at room temperature or 4 °C. Some aliquots were preserved using hydrochloric acid prior to storage, some thereafter, some using the BD Urine preservation tube and some were not preserved at all. Storage duration was 0, 24, 48 or 72 h. In all samples calcium, magnesium, phosphorus, creatinine, oxalate, citrate and uric acid were measured and compared to the according reference sample. RESULTS: We could not find any significant deviation for any of the analytes and preanalytical treatment conditions compared to the associated reference sample. CONCLUSION: Preservation of 24 h urine for the metabolic evaluation in stone formers might not be necessary for sample storage up to 72 h.
Find related publications in this database (using NLM MeSH Indexing)
Aged - administration & dosage
Calcium - administration & dosage
Citric Acid - administration & dosage
Humans - administration & dosage
Hydrogen-Ion Concentration - administration & dosage
Magnesium - administration & dosage
Risk Factors - administration & dosage
Urolithiasis - diagnosis, urine

Find related publications in this database (Keywords)
Preanalytical phase
Kidney stone
Secondary prevention
Metabolic evaluation
Urine preservation
Stone former patients
© Med Uni Graz Impressum