Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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1234 Publikationen des Forschungsfeldes "Molekulare Grundlagen Lipid-assoziierter Erkrankungen (Beendet 2020)":

2021

Vujić, N; Bradić, I; Goeritzer, M; Kuentzel, KB; Rainer, S; Kratky, D; Radović, B ATG7 is dispensable for LC3-PE conjugation in thioglycolate-elicited mouse peritoneal macrophages.
Autophagy. 2021; 17(11):3402-3407 Doi: 10.1080/15548627.2021.1874132 [OPEN ACCESS]
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Dalkner, N; Bengesser, S; Birner, A; Rieger, A; Seebauer, J; Platzer, M; Hamm, C; Maget, A; Queissner, R; Pilz, R; Fellendorf, FT; Reininghaus, B; Strassnig, MT; Kapfhammer, HP; Weiss, EM; Reininghaus, EZ Body Mass Index Predicts Decline in Executive Function in Bipolar Disorder: Preliminary Data of a 12-Month Follow-up Study.
Neuropsychobiology. 2021; 80(1):1-11 Doi: 10.1159/000505784
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Knuplez, E; Kienzl, M; Trakaki, A; Schicho, R; Heinemann, A; Sturm, EM; Marsche, G The anti-parasitic drug miltefosine suppresses human eosinophil activation and ameliorates murine allergic inflammation in vivo.
Br J Pharmacol. 2021; 178(5):1234-1248 Doi: 10.1111/bph.15368 [OPEN ACCESS]
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Züllig, T; Köfeler, HC HIGH RESOLUTION MASS SPECTROMETRY IN LIPIDOMICS.
Mass Spectrom Rev. 2021; 40(3):162-176 Doi: 10.1002/mas.21627 [OPEN ACCESS]
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Wunderling, K; Leopold, C; Jamitzky, I; Yaghmour, M; Zink, F; Kratky, D; Thiele, C Hepatic synthesis of triacylglycerols containing medium-chain fatty acids is dominated by diacylglycerol acyltransferase 1 and efficiently inhibited by etomoxir.
Mol Metab. 2020; 45: 101150-101150. Doi: 10.1016/j.molmet.2020.101150 [OPEN ACCESS]
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Panzitt, K; Fickert, P; Wagner, M Regulation of autophagy by bile acids and in cholestasis - CholestoPHAGY or CholeSTOPagy.
Biochim Biophys Acta Mol Basis Dis. 2021; 1867(2):166017-166017 Doi: 10.1016/j.bbadis.2020.166017
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Schilcher, I; Stadler, JT; Lechleitner, M; Hrzenjak, A; Berghold, A; Pregartner, G; Lhomme, M; Holzer, M; Korbelius, M; Reichmann, F; Springer, A; Wadsack, C; Madl, T; Kratky, D; Kontush, A; Marsche, G; Frank, S Endothelial Lipase Modulates Paraoxonase 1 Content and Arylesterase Activity of HDL.
Int J Mol Sci. 2021; 22(2): Doi: 10.3390/ijms22020719 [OPEN ACCESS]
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Luan, W; Hao, CZ; Li, JQ; Wei, Q; Gong, JY; Qiu, YL; Lu, Y; Shen, CH; Xia, Q; Xie, XB; Zhang, MH; Abuduxikuer, K; Li, ZD; Wang, L; Xing, QH; Knisely, AS; Wang, JS Biallelic loss-of-function ZFYVE19 mutations are associated with congenital hepatic fibrosis, sclerosing cholangiopathy and high-GGT cholestasis.
J Med Genet. 2021; 58(8):514-525 Doi: 10.1136/jmedgenet-2019-106706
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Fallah, S; Marsche, G; Mohamadinarab, M; Mohassel Azadi, S; Ghasri, H; Fadaei, R; Moradi, N Impaired cholesterol efflux capacity in patients with Helicobacter pylori infection and its relation with inflammation.
J Clin Lipidol. 2020; 15(1):218-226 Doi: 10.1016/j.jacl.2020.11.005
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Stadler, JT; Lackner, S; Mörkl, S; Trakaki, A; Scharnagl, H; Borenich, A; Wonisch, W; Mangge, H; Zelzer, S; Meier-Allard, N; Holasek, SJ; Marsche, G Obesity Affects HDL Metabolism, Composition and Subclass Distribution.
Biomedicines. 2021; 9(3): Doi: 10.3390/biomedicines9030242 [OPEN ACCESS]
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Knisely, AS; Houwen, RHJ Liver Steatosis and Diarrhea After Liver Transplantation for Progressive Familial Intrahepatic Cholestasis Type 1: Can Biliary Diversion Solve These Problems?
J Pediatr Gastroenterol Nutr. 2021; 72(3):341-342 Doi: 10.1097/MPG.0000000000002990
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Aengenheister, L; Favaro, RR; Morales-Prieto, DM; Furer, LA; Gruber, M; Wadsack, C; Markert, UR; Buerki-Thurnherr, T Research on nanoparticles in human perfused placenta: State of the art and perspectives.
Placenta. 2021; 104:199-207 Doi: 10.1016/j.placenta.2020.12.014 [OPEN ACCESS]
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Traussnigg, S; Halilbasic, E; Hofer, H; Munda, P; Stojakovic, T; Fauler, G; Kashofer, K; Krssak, M; Wolzt, M; Trauner, M Open-label phase II study evaluating safety and efficacy of the non-steroidal farnesoid X receptor agonist PX-104 in non-alcoholic fatty liver disease.
Wien Klin Wochenschr. 2021; 133(9-10):441-451 Doi: 10.1007/s00508-020-01735-5 [OPEN ACCESS]
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Niedrist, T; Mangge, H; Herrman, M Comparison of Automated Procalcitonin Immunoassays under Routine Conditions.
Clin Lab. 2021; 67(1): Doi: 10.7754/Clin.Lab.2020.200457
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2020

Kleber, ME; Delgado, GE; März, W LDL receptor traffic: in the fast lane.
Eur Heart J. 2020; 41(9):1054-1056 Doi: 10.1093/eurheartj/ehz866
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Paschoal, VA; Walenta, E; Talukdar, S; Pessentheiner, AR; Osborn, O; Hah, N; Chi, TJ; Tye, GL; Armando, AM; Evans, RM; Chi, NW; Quehenberger, O; Olefsky, JM; Oh, DY Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity.
Cell Metab. 2020; 31(6): 1173-1188. Doi: 10.1016/j.cmet.2020.04.020 [OPEN ACCESS]
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Smole, U; Gour, N; Phelan, J; Hofer, G; Köhler, C; Kratzer, B; Tauber, PA; Xiao, X; Yao, N; Dvorak, J; Caraballo, L; Puerta, L; Rosskopf, S; Chakir, J; Malle, E; Lane, AP; Pickl, WF; Lajoie, S; Wills-Karp, M Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity.
Nat Immunol. 2020; 21(7):756-765 Doi: 10.1038/s41590-020-0698-1 [OPEN ACCESS]
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Zewinger, S; Reiser, J; Jankowski, V; Alansary, D; Hahm, E; Triem, S; Klug, M; Schunk, SJ; Schmit, D; Kramann, R; Körbel, C; Ampofo, E; Laschke, MW; Selejan, SR; Paschen, A; Herter, T; Schuster, S; Silbernagel, G; Sester, M; Sester, U; Aßmann, G; Bals, R; Kostner, G; Jahnen-Dechent, W; Menger, MD; Rohrer, L; März, W; Böhm, M; Jankowski, J; Kopf, M; Latz, E; Niemeyer, BA; Fliser, D; Laufs, U; Speer, T Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation.
Nat Immunol. 2020; 21(1): 30-41. Doi: 10.1038/s41590-019-0548-1
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Norel, X; Sugimoto, Y; Ozen, G; Abdelazeem, H; Amgoud, Y; Bouhadoun, A; Bassiouni, W; Goepp, M; Mani, S; Manikpurage, HD; Senbel, A; Longrois, D; Heinemann, A; Yao, C; Clapp, LH International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions.
Pharmacol Rev. 2020; 72(4): 910-968. Doi: 10.1124/pr.120.019331 [OPEN ACCESS]
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Panzitt, K; Jungwirth, E; Krones, E; Lee, JM; Pollheimer, M; Thallinger, GG; Kolb-Lenz, D; Xiao, R; Thorell, A; Trauner, M; Fickert, P; Marschall, HU; Moore, DD; Wagner, M FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis.
J Hepatol. 2020; 72(6):1122-1131 Doi: 10.1016/j.jhep.2020.01.014 [OPEN ACCESS]
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Trieb, M; Rainer, F; Stadlbauer, V; Douschan, P; Horvath, A; Binder, L; Trakaki, A; Knuplez, E; Scharnagl, H; Stojakovic, T; Heinemann, Á; Mandorfer, M; Paternostro, R; Reiberger, T; Pitarch, C; Amorós, A; Gerbes, A; Caraceni, P; Alessandria, C; Moreau, R; Clària, J; Marsche, G; Stauber, RE HDL-related biomarkers are robust predictors of survival in patients with chronic liver failure.
J Hepatol. 2020; 73(1):113-120 Doi: 10.1016/j.jhep.2020.01.026 [OPEN ACCESS]
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Pfeil, EM; Brands, J; Merten, N; Vögtle, T; Vescovo, M; Rick, U; Albrecht, IM; Heycke, N; Kawakami, K; Ono, Y; Ngako Kadji, FM; Hiratsuka, S; Aoki, J; Häberlein, F; Matthey, M; Garg, J; Hennen, S; Jobin, ML; Seier, K; Calebiro, D; Pfeifer, A; Heinemann, A; Wenzel, D; König, GM; Nieswandt, B; Fleischmann, BK; Inoue, A; Simon, K; Kostenis, E Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs.
Mol Cell. 2020; 80(6):940-954 Doi: 10.1016/j.molcel.2020.10.027
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Choi, S; Dong, B; Lin, CJ; Heo, MJ; Kim, KH; Sun, Z; Wagner, M; Putluri, N; Suh, JM; Wang, MC; Moore, DD Methyl-Sensing Nuclear Receptor Liver Receptor Homolog-1 Regulates Mitochondrial Function in Mouse Hepatocytes.
Hepatology. 2020; 71(3):1055-1069 Doi: 10.1002/hep.30884 [OPEN ACCESS]
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Tardelli, M; Bruschi, FV; Fuchs, CD; Claudel, T; Auer, N; Kunczer, V; Baumgartner, M; Ronda, OAHO; Jan Verkade, H; Stojakovic, T; Scharnagl, H; Habib, A; Zimmermann, R; Lotersztajn, S; Trauner, M Monoacylglycerol lipase inhibition protects from liver injury in mouse models of sclerosing cholangitis.
Hepatology. 2020; Doi: 10.1002/hep.30929 [OPEN ACCESS]
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Alexopoulos, SJ; Chen, SY; Brandon, AE; Salamoun, JM; Byrne, FL; Garcia, CJ; Beretta, M; Olzomer, EM; Shah, DP; Philp, AM; Hargett, SR; Lawrence, RT; Lee, B; Sligar, J; Carrive, P; Tucker, SP; Philp, A; Lackner, C; Turner, N; Cooney, GJ; Santos, WL; Hoehn, KL Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice.
Nat Commun. 2020; 11(1):2397-2397 Doi: 10.1038/s41467-020-16298-2 [OPEN ACCESS]
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Wagner, M; Fickert, P Drug Therapies for Chronic Cholestatic Liver Diseases.
Annu Rev Pharmacol Toxicol. 2020; 60(1):503-527 Doi: 10.1146/annurev-pharmtox-010818-021059
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Roula, D; Theiler, A; Luschnig, P; Sturm, GJ; Tomazic, PV; Marsche, G; Heinemann, A; Sturm, EM Apolipoprotein A-IV acts as an endogenous anti-inflammatory protein and is reduced in treatment-naïve allergic patients and allergen-challenged mice.
Allergy. 2020; 75(2):392-402 Doi: 10.1111/all.14022 [OPEN ACCESS]
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Heine, GH; Eller, K; Stadler, JT; Rogacev, KS; Marsche, G, ;RITERM, study, group;RITERM, study, group Lipid-modifying therapy in chronic kidney disease: Pathophysiological and clinical considerations.
Pharmacol Ther. 2020; 207:107459 Doi: 10.1016/j.pharmthera.2019.107459
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Sladky, VC; Knapp, K; Soratroi, C; Heppke, J; Eichin, F; Rocamora-Reverte, L; Szabo, TG; Bongiovanni, L; Westendorp, B; Moreno, E; van Liere, EA; Bakker, B; Spierings, DCJ; Wardenaar, R; Pereyra, D; Starlinger, P; Schultze, S; Trauner, M; Stojakovic, T; Scharnagl, H; Fava, LL; Foijer, F; de Bruin, A; Villunger, A E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration.
Dev Cell. 2020; 52(3):335-349 Doi: 10.1016/j.devcel.2019.12.016
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Bärnthaler, T; Theiler, A; Zabini, D; Trautmann, S; Stacher-Priehse, E; Lanz, I; Klepetko, W; Sinn, K; Flick, H; Scheidl, S; Thomas, D; Olschewski, H; Kwapiszewska, G; Schuligoi, R; Heinemann, A Inhibiting eicosanoid degradation exerts antifibrotic effects in a pulmonary fibrosis mouse model and human tissue.
J Allergy Clin Immunol. 2020; 145(3):818-833 Doi: 10.1016/j.jaci.2019.11.032 [OPEN ACCESS]
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Kolleritsch, S; Kien, B; Schoiswohl, G; Diwoky, C; Schreiber, R; Heier, C; Maresch, LK; Schweiger, M; Eichmann, TO; Stryeck, S; Krenn, P; Tomin, T; Schittmayer, M; Kolb, D; Rülicke, T; Hoefler, G; Wolinski, H; Madl, T; Birner-Gruenberger, R; Haemmerle, G Low cardiac lipolysis reduces mitochondrial fission and prevents lipotoxic heart dysfunction in Perilipin 5 mutant mice.
Cardiovasc Res. 2020; 116(2):339-352 Doi: 10.1093/cvr/cvz119 [OPEN ACCESS]
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Streidl, T; Karkossa, I; Segura, Muñoz, RR; Eberl, C; Zaufel, A; Plagge, J; Schmaltz, R; Schubert, K; Basic, M; Schneider, KM; Afify, M; Trautwein, C; Tolba, R; Stecher, B; Doden, HL; Ridlon, JM; Ecker, J; Moustafa, T; von, Bergen, M; Ramer-Tait, AE; Clavel, T The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice.
GUT MICROBES. 2020; 13(1): 1-21. Doi: 10.1080/19490976.2020.1854008 [OPEN ACCESS]
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Cantalupo, A; Sasset, L; Gargiulo, A; Rubinelli, L; Del Gaudio, I; Benvenuto, D; Wadsack, C; Jiang, XC; Bucci, MR; Di Lorenzo, A Endothelial Sphingolipid De Novo Synthesis Controls Blood Pressure by Regulating Signal Transduction and NO via Ceramide.
Hypertension. 2020; 75(5):1279-1288 Doi: 10.1161/HYPERTENSIONAHA.119.14507 [OPEN ACCESS]
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Sladky, VC; Knapp, K; Szabo, TG; Braun, VZ; Bongiovanni, L; van den Bos, H; Spierings, DC; Westendorp, B; Curinha, A; Stojakovic, T; Scharnagl, H; Timelthaler, G; Tsuchia, K; Pinter, M; Semmler, G; Foijer, F; de Bruin, A; Reiberger, T; Rohr-Udilova, N; Villunger, A PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis.
EMBO Rep. 2020; 21(12):e50893-e50893 Doi: 10.15252/embr.202050893 [OPEN ACCESS]
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Plastira, I; Bernhart, E; Joshi, L; Koyani, CN; Strohmaier, H; Reicher, H; Malle, E; Sattler, W MAPK signaling determines lysophosphatidic acid (LPA)-induced inflammation in microglia.
J Neuroinflammation. 2020; 17(1): 127-127. Doi: 10.1186/s12974-020-01809-1 [OPEN ACCESS]
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Dong, J; He, M; Li, J; Pessentheiner, A; Wang, C; Zhang, J; Sun, Y; Wang, WT; Zhang, Y; Liu, J; Wang, SC; Huang, PH; Gordts, PL; Yuan, ZY; Tsimikas, S; Shyy, JY microRNA-483 ameliorates hypercholesterolemia by inhibiting PCSK9 production.
JCI Insight. 2020; 5(23): Doi: 10.1172/jci.insight.143812 [OPEN ACCESS]
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Gutiérrez, T; Qi, H; Yap, MC; Tahbaz, N; Milburn, LA; Lucchinetti, E; Lou, PH; Zaugg, M; LaPointe, PG; Mercier, P; Overduin, M; Bischof, H; Burgstaller, S; Malli, R; Ballanyi, K; Shuai, J; Simmen, T The ER chaperone calnexin controls mitochondrial positioning and respiration.
Sci Signal. 2020; 13(638): Doi: 10.1126/scisignal.aax6660
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Gerndt, S; Chen, CC; Chao, YK; Yuan, Y; Burgstaller, S; Scotto, Rosato, A; Krogsaeter, E; Urban, N; Jacob, K; Nguyen, ONP; Miller, MT; Keller, M; Vollmar, AM; Gudermann, T; Zierler, S; Schredelseker, J; Schaefer, M; Biel, M; Malli, R; Wahl-Schott, C; Bracher, F; Patel, S; Grimm, C Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function.
Elife. 2020; 9: Doi: 10.7554/eLife.54712 [OPEN ACCESS]
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Koyani, CN; Plastira, I; Sourij, H; Hallström, S; Schmidt, A; Rainer, PP; Bugger, H; Frank, S; Malle, E; von, Lewinski, D Empagliflozin protects heart from inflammation and energy depletion via AMPK activation.
Pharmacol Res. 2020; 158:104870 Doi: 10.1016/j.phrs.2020.104870
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Pessentheiner, AR; Ducasa, GM; Gordts, PLSM Proteoglycans in Obesity-Associated Metabolic Dysfunction and Meta-Inflammation.
Front Immunol. 2020; 11(23): 769-769. Doi: 10.3389/fimmu.2020.00769 [OPEN ACCESS]
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Hartler, J; Armando, AM; Trötzmüller, M; Dennis, EA; Köfeler, HC; Quehenberger, O
Anal Chem. 2020; 92(20):14054-14062 Doi: 10.1021/acs.analchem.0c03016 [OPEN ACCESS]
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Lajin, B; Goessler, W Fluoroalkylamines: Novel, Highly Volatile, Fast-Equilibrating, and Electrospray Ionization-Mass Spectrometry Signal-Enhancing Cationic Ion-Interaction Reagents.
Anal Chem. 2020; 92(14): 10121-10128. Doi: 10.1021/acs.analchem.0c02138 [OPEN ACCESS]
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Lajin, B; Goessler, W Simultaneous Determination of Chlorinated and Brominated Acetic Acids in Various Environmental Water Matrixes by High-Performance Liquid Chromatography-Inductively Coupled Plasma Tandem Mass Spectrometry without Sample Preparation.
Anal Chem. 2020; 92(13): 9156-9163. Doi: 10.1021/acs.analchem.0c01456 [OPEN ACCESS]
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Lajin, B; Goessler, W HPLC-ICPMS/MS shows a significant advantage over HPLC-ICPMS for the determination of perchlorate in ground, tap, and river water.
Anal Chim Acta. 2020; 1094(13): 11-17. Doi: 10.1016/j.aca.2019.09.070
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Tupova, L; Hirschmugl, B; Sucha, S; Pilarova, V; Székely, V; Bakos, É; Novakova, L; Özvegy-Laczka, C; Wadsack, C; Ceckova, M Interplay of drug transporters P-glycoprotein (MDR1), MRP1, OATP1A2 and OATP1B3 in passage of maraviroc across human placenta.
Biomed Pharmacother. 2020; 129(11):110506-110506 Doi: 10.1016/j.biopha.2020.110506 [OPEN ACCESS]
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Zwickl, H; Hackner, K; Köfeler, H; Krzizek, EC; Muqaku, B; Pils, D; Scharnagl, H; Solheim, TS; Zwickl-Traxler, E; Pecherstorfer, M Reduced LDL-Cholesterol and Reduced Total Cholesterol as Potential Indicators of Early Cancer in Male Treatment-Naïve Cancer Patients With Pre-cachexia and Cachexia.
Front Oncol. 2020; 10(9):1262-1262 Doi: 10.3389/fonc.2020.01262 [OPEN ACCESS]
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Ritsch, A; Duerr, A; Kahler, P; Hunjadi, M; Stojakovic, T; Silbernagel, G; Scharnagl, H; Kleber, ME; März, W Cholesterol Efflux Capacity and Cardiovascular Disease: The Ludwigshafen Risk and Cardiovascular Health (LURIC) Study.
Biomedicines. 2020; 8(11): Doi: 10.3390/biomedicines8110524 [OPEN ACCESS]
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Trakaki, A; Marsche, G High-Density Lipoprotein (HDL) in Allergy and Skin Diseases: Focus on Immunomodulating Functions.
Biomedicines. 2020; 8(12): Doi: 10.3390/biomedicines8120558 [OPEN ACCESS]
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Del Gaudio, I; Sasset, L; Lorenzo, AD; Wadsack, C Sphingolipid Signature of Human Feto-Placental Vasculature in Preeclampsia.
Int J Mol Sci. 2020; 21(3): Doi: 10.3390/ijms21031019 [OPEN ACCESS]
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Gaudio, ID; Hendrix, S; Christoffersen, C; Wadsack, C Neonatal HDL Counteracts Placental Vascular Inflammation via S1P-S1PR1 Axis.
Int J Mol Sci. 2020; 21(3): Doi: 10.3390/ijms21030789 [OPEN ACCESS]
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Goeritzer, M; Bernhart, E; Plastira, I; Reicher, H; Leopold, C; Eichmann, TO; Rechberger, G; Madreiter-Sokolowski, CT; Prasch, J; Eller, P; Graier, WF; Kratky, D; Malle, E; Sattler, W Myeloperoxidase and Septic Conditions Disrupt Sphingolipid Homeostasis in Murine Brain Capillaries In Vivo and Immortalized Human Brain Endothelial Cells In Vitro.
Int J Mol Sci. 2020; 21(3): 1143 Doi: 10.3390/ijms21031143 [OPEN ACCESS]
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Kienzl, M; Kargl, J; Schicho, R The Immune Endocannabinoid System of the Tumor Microenvironment.
Int J Mol Sci. 2020; 21(23): Doi: 10.3390/ijms21238929 [OPEN ACCESS]
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Knuplez, E; Marsche, G An Updated Review of Pro- and Anti-Inflammatory Properties of Plasma Lysophosphatidylcholines in the Vascular System.
Int J Mol Sci. 2020; 21(12): Doi: 10.3390/ijms21124501 [OPEN ACCESS]
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Prasch, J; Bernhart, E; Reicher, H; Kollroser, M; Rechberger, GN; Koyani, CN; Trummer, C; Rech, L; Rainer, PP; Hammer, A; Malle, E; Sattler, W Myeloperoxidase-Derived 2-Chlorohexadecanal Is Generated in Mouse Heart during Endotoxemia and Induces Modification of Distinct Cardiomyocyte Protein Subsets In Vitro.
Int J Mol Sci. 2020; 21(23): Doi: 10.3390/ijms21239235 [OPEN ACCESS]
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Stadler, JT; Marsche, G Obesity-Related Changes in High-Density Lipoprotein Metabolism and Function.
Int J Mol Sci. 2020; 21(23): Doi: 10.3390/ijms21238985 [OPEN ACCESS]
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Grabner, GF; Fawzy, N; Schreiber, R; Pusch, LM; Bulfon, D; Koefeler, H; Eichmann, TO; Lass, A; Schweiger, M; Marsche, G; Schoiswohl, G; Taschler, U; Zimmermann, R Metabolic regulation of the lysosomal cofactor bis(monoacylglycero)phosphate in mice.
J Lipid Res. 2020; 61(7): 995-1003. Doi: 10.1194/jlr.RA119000516 [OPEN ACCESS]
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Liebisch, G; Fahy, E; Aoki, J; Dennis, EA; Durand, T; Ejsing, CS; Fedorova, M; Feussner, I; Griffiths, WJ; Kofeler, H; Merrill, AH; Murphy, RC; O'Donnell, VB; Oskolkova, O; Subramaniam, S; Wakelam, MJO; Spener, F Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures.
J LIPID RES. 2020; 61(12): 1539-1555. Doi: 10.1194/jlr.S120001025 [OPEN ACCESS]
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Safari, Z; Bruneau, A; Monnoye, M; Mariadassou, M; Philippe, C; Zatloukal, K; Gérard, P Murine Genetic Background Overcomes Gut Microbiota Changes to Explain Metabolic Response to High-Fat Diet.
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Knuplez, E; Krier-Burris, R; Cao, Y; Marsche, G; O'Sullivan, J; Bochner, BS Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls.
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Valencak, TG; Spenlingwimmer, T; Nimphy, R; Reinisch, I; Hoffman, JM; Prokesch, A Challenging a "Cushy" Life: Potential Roles of Thermogenesis and Adipose Tissue Adaptations in Delayed Aging of Ames and Snell Dwarf Mice.
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Marsche, G; Heine, GH; Stadler, JT; Holzer, M Current Understanding of the Relationship of HDL Composition, Structure and Function to Their Cardioprotective Properties in Chronic Kidney Disease.
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Hum Mutat. 2020; 41(2):502-511 Doi: 10.1002/humu.23947
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Olivieri, O; Speziali, G; Castagna, A; Pattini, P; Udali, S; Pizzolo, F; Liesinger, L; Gindlhuber, J; Tomin, T; Schittmayer, M; Birner-Gruenberger, R; Cecconi, D; Girelli, D; Friso, S; Martinelli, N The Positive Association between Plasma Myristic Acid and ApoCIII Concentrations in Cardiovascular Disease Patients Is Supported by the Effects of Myristic Acid in HepG2 Cells.
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Lajin, B; Goessler, W Fluorinated carboxylic acids as "ion repelling agents" in reversed-phase chromatography.
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Del Gaudio, I; Sreckovic, I; Zardoya-Laguardia, P; Bernhart, E; Christoffersen, C; Frank, S; Marsche, G; Illanes, SE; Wadsack, C Circulating cord blood HDL-S1P complex preserves the integrity of the feto-placental vasculature.
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Knuplez, E; Curcic, S; Theiler, A; Bärnthaler, T; Trakaki, A; Trieb, M; Holzer, M; Heinemann, A; Zimmermann, R; Sturm, EM; Marsche, G Lysophosphatidylcholines inhibit human eosinophil activation and suppress eosinophil migration in vivo.
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Wagner, C; Hois, V; Pajed, L; Pusch, LM; Wolinski, H; Trauner, M; Zimmermann, R; Taschler, U; Lass, A Lysosomal acid lipase is the major acid retinyl ester hydrolase in cultured human hepatic stellate cells but not essential for retinyl ester degradation.
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Xie, H; Heier, C; Kien, B; Vesely, PW; Tang, Z; Sexl, V; Schoiswohl, G; Strießnig-Bina, I; Hoefler, G; Zechner, R; Schweiger, M Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling.
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Wagner, J; Knaier, R; Königstein, K; Klenk, C; Carrard, J; Lichtenstein, E; Scharnagl, H; März, W; Hanssen, H; Hinrichs, T; Schmidt-Trucksäss, A; Arbeev, K Composite Measures of Physical Fitness to Discriminate Between Healthy Aging and Heart Failure: The COmPLETE Study.
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Kienzl, M; Storr, M; Schicho, R Cannabinoids and Opioids in the Treatment of Inflammatory Bowel Diseases.
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Trakaki, A; Scharnagl, H; Trieb, M; Holzer, M; Hinghofer-Szalkay, H; Goswami, N; Marsche, G Prolonged bedrest reduces plasma high-density lipoprotein levels linked to markedly suppressed cholesterol efflux capacity.
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Vogel, GF; Maurer, E; Entenmann, A; Straub, S; Knisely, AS; Janecke, AR; Müller, T Co-existence of ABCB11 and DCDC2 disease: Infantile cholestasis requires both next-generation sequencing and clinical-histopathologic correlation.
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Trummer, O; Schweighofer, N; Haudum, CW; Trummer, C; Pilz, S; Theiler-Schwetz, V; Keppel, MH; Grübler, M; Pieber, TR; Renner, W; Obermayer-Pietsch, B; Lerchbaum, E Genetic Components of 25-Hydroxyvitamin D Increase in Three Randomized Controlled Trials.
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Züllig, T; Trötzmüller, M; Köfeler, HC Lipidomics from sample preparation to data analysis: a primer.
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Katzmann, JL; Werner, CM; Stojakovic, T; März, W; Scharnagl, H; Laufs, U Apolipoprotein CIII predicts cardiovascular events in patients with coronary artery disease: a prospective observational study.
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Leskelä, J; Pietiäinen, M; Safer, A; Lehto, M; Metso, J; Malle, E; Buggle, F; Becher, H; Sundvall, J; Grau, AJ; Pussinen, PJ; Palm, F Serum lipopolysaccharide neutralizing capacity in ischemic stroke.
PLoS One. 2020; 15(2): e0228806-e0228806. Doi: 10.1371/journal.pone.0228806 [OPEN ACCESS]
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Delgado, GE; Krämer, BK; Scharnagl, H; Fauler, G; Stojakovic, T; März, W; Kleber, ME; Lammert, A Bile Acids in Patients with Uncontrolled Type 2 Diabetes Mellitus - The Effect of Two Days of Oatmeal Treatment.
Exp Clin Endocrinol Diabetes. 2020; 128(9):624-630 Doi: 10.1055/a-1069-7330
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Dezsőfi, A; Knisely, AS Liver Biopsy in High-risk Children: Which Way to Go?
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Schmidt, N; Klose, G; Schatz, U; Laufs, U; Marz, W Familial Hypercholesterolemia in Germany.
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Holzer, M; Marsche, G Comment on Mathew et al. Therapeutic Lifestyle Changes Improve HDL Function by Inhibiting Myeloperoxidase-Mediated Oxidation in Patients With Metabolic Syndrome. Diabetes Care 2018;41:2431-2437.
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Zhu, XG; Nicholson Puthenveedu, S; Shen, Y; La, K; Ozlu, C; Wang, T; Klompstra, D; Gultekin, Y; Chi, J; Fidelin, J; Peng, T; Molina, H; Hang, HC; Min, W; Birsoy, K CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4.
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Curcic, S; Tiapko, O; Groschner, K Photopharmacology and opto-chemogenetics of TRPC channels-some therapeutic visions.
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Kaufman, S; Arnold, M; Diaz, AA; Neubauer, H; Wolfrum, S; Köfeler, H; Langhans, W; Krieger, JP Roux-en-Y gastric bypass surgery reprograms enterocyte triglyceride metabolism and postprandial secretion in rats.
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Maki, RA; Holzer, M; Motamedchaboki, K; Malle, E; Masliah, E; Marsche, G; Reynolds, WF Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment.
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Vanichkitrungruang, S; Chuang, CY; Hawkins, CL; Hammer, A; Hoefler, G; Malle, E; Davies, MJ Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function.
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Fotoulaki, M; Giza, S; Jirsa, M; Grammatikopoulos, T; Miquel, R; Hytiroglou, P; Tsitouridis, I; Knisely, AS Beyond an Obvious Cause of Cholestasis in a Toddler: Compound Heterozygosity for ABCB11 Mutations.
PEDIATRICS. 2019; 143(5): Doi: 10.1542/peds.2018-2146 [OPEN ACCESS]
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Torner, M; Mangal, A; Scharnagl, H; Jansen, C; Praktiknjo, M; Queck, A; Gu, W; Schierwagen, R; Lehmann, J; Uschner, FE; Graf, C; Strassburg, CP; Fernandez, J; Stojakovic, T; Woitas, R; Trebicka, J Sex specificity of kidney markers to assess prognosis in cirrhotic patients with TIPS.
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Cadenas, C; Vosbeck, S; Edlund, K; Grgas, K; Madjar, K; Hellwig, B; Adawy, A; Glotzbach, A; Stewart, JD; Lesjak, MS; Franckenstein, D; Claus, M; Hayen, H; Schriewer, A; Gianmoena, K; Thaler, S; Schmidt, M; Micke, P; Pontén, F; Mardinoglu, A; Zhang, C; Käfferlein, HU; Watzl, C; Frank, S; Rahnenführer, J; Marchan, R; Hengstler, JG LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer.
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Hofer, DC; Zirkovits, G; Pelzmann, HJ; Huber, K; Pessentheiner, AR; Xia, W; Uno, K; Miyazaki, T; Kon, K; Tsuneki, H; Pendl, T; Al Zoughbi, W; Madreiter-Sokolowski, CT; Trausinger, G; Abdellatif, M; Schoiswohl, G; Schreiber, R; Eisenberg, T; Magnes, C; Sedej, S; Eckhardt, M; Sasahara, M; Sasaoka, T; Nitta, A; Hoefler, G; Graier, WF; Kratky, D; Auwerx, J; Bogner-Strauss, JG N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health.
FASEB J. 2019; 33(12):13808-13824 Doi: 10.1096/fj.201801323R [OPEN ACCESS]
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Butorac, C; Muik, M; Derler, I; Stadlbauer, M; Lunz, V; Krizova, A; Lindinger, S; Schober, R; Frischauf, I; Bhardwaj, R; Hediger, MA; Groschner, K; Romanin, C A novel STIM1-Orai1 gating interface essential for CRAC channel activation.
CELL CALCIUM. 2019; 79(6): 57-67. Doi: 10.1016/j.ceca.2019.02.009 [OPEN ACCESS]
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Svobodova, B; Lichtenegger, M; Platzer, D; Di Giuro, CML; de la Cruz, GG; Glasnov, T; Schreibmayer, W; Groschner, K A single point mutation in the TRPC3 lipid-recognition window generates supersensitivity to benzimidazole channel activators.
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Blom, WAM; Koppenol, WP; Hiemstra, H; Stojakovic, T; Scharnagl, H; Trautwein, EA A low-fat spread with added plant sterols and fish omega-3 fatty acids lowers serum triglyceride and LDL-cholesterol concentrations in individuals with modest hypercholesterolaemia and hypertriglyceridaemia.
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Klec, C; Ziomek, G; Pichler, M; Malli, R; Graier, WF Calcium Signaling in ß-cell Physiology and Pathology: A Revisit.
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Leopold, C; Duta-Mare, M; Sachdev, V; Goeritzer, M; Maresch, LK; Kolb, D; Reicher, H; Wagner, B; Stojakovic, T; Ruelicke, T; Haemmerle, G; Hoefler, G; Sattler, W; Kratky, D Hepatocyte-specific lysosomal acid lipase deficiency protects mice from diet-induced obesity but promotes hepatic inflammation.
Biochim Biophys Acta Mol Cell Biol Lipids. 2019; 1864(4):500-511 Doi: 10.1016/j.bbalip.2019.01.007 [OPEN ACCESS]
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Schilcher, I; Ledinski, G; Radulović, S; Hallström, S; Eichmann, T; Madl, T; Zhang, F; Leitinger, G; Kolb-Lenz, D; Darnhofer, B; Birner-Gruenberger, R; Wadsack, C; Kratky, D; Marsche, G; Frank, S; Cvirn, G Endothelial lipase increases antioxidative capacity of high-density lipoprotein.
Biochim Biophys Acta Mol Cell Biol Lipids. 2019; 1864(10):1363-1374 Doi: 10.1016/j.bbalip.2019.06.011 [OPEN ACCESS]
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Trakaki, A; Sturm, GJ; Pregartner, G; Scharnagl, H; Eichmann, TO; Trieb, M; Knuplez, E; Holzer, M; Stadler, JT; Heinemann, A; Sturm, EM; Marsche, G Allergic rhinitis is associated with complex alterations in high-density lipoprotein composition and function.
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Grabner, GF; Fawzy, N; Pribasnig, MA; Trieb, M; Taschler, U; Holzer, M; Schweiger, M; Wolinski, H; Kolb, D; Horvath, A; Breinbauer, R; Rülicke, T; Rabl, R; Lass, A; Stadlbauer, V; Hutter-Paier, B; Stauber, RE; Fickert, P; Zechner, R; Marsche, G; Eichmann, TO; Zimmermann, R Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans.
J Lipid Res. 2019; 60(5):1020-1031 Doi: 10.1194/jlr.M093351 [OPEN ACCESS]
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Ramms, B; Patel, S; Nora, C; Pessentheiner, AR; Chang, MW; Green, CR; Golden, GJ; Secrest, P; Krauss, RM; Metallo, CM; Benner, C; Alexander, VJ; Witztum, JL; Tsimikas, S; Esko, JD; Gordts, PLSM ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance.
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Silbernagel, G; Steiner, LK; Hollstein, T; Fauler, G; Scharnagl, H; Stojakovic, T; Schumann, F; Bölükbasi, B; März, W; Steinhagen-Thiessen, E; Laufs, U; Kassner, U The interrelations between PCSK9 metabolism and cholesterol synthesis and absorption.
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Tardelli, M; Bruschi, FV; Claudel, T; Fuchs, CD; Auer, N; Kunczer, V; Stojakovic, T; Scharnagl, H; Habib, A; Grabner, GF; Zimmermann, R; Lotersztajn, S; Trauner, M Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption.
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Bischof, H; Burgstaller, S; Waldeck-Weiermair, M; Rauter, T; Schinagl, M; Ramadani-Muja, J; Graier, WF; Malli, R Live-Cell Imaging of Physiologically Relevant Metal Ions Using Genetically Encoded FRET-Based Probes.
Cells. 2019; 8(5): Doi: 10.3390/cells8050492 [OPEN ACCESS]
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Rittchen, S; Heinemann, A Therapeutic Potential of Hematopoietic Prostaglandin D2 Synthase in Allergic Inflammation.
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Denk, H; Abuja, PM; Zatloukal, K Animal models of NAFLD from the pathologist's point of view.
Biochim Biophys Acta Mol Basis Dis. 2019; 1865(5):929-942 Doi: 10.1016/j.bbadis.2018.04.024 [OPEN ACCESS]
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Fanaee-Danesh, E; Gali, CC; Tadic, J; Zandl-Lang, M; Carmen Kober, A; Agujetas, VR; de Dios, C; Tam-Amersdorfer, C; Stracke, A; Albrecher, NM; Manavalan, APC; Reiter, M; Sun, Y; Colell, A; Madeo, F; Malle, E; Panzenboeck, U Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
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Fickert, P; Wagner, M Preface - Animal models in liver disease.
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Pajed, L; Wagner, C; Taschler, U; Schreiber, R; Kolleritsch, S; Fawzy, N; Pototschnig, I; Schoiswohl, G; Pusch, LM; Wieser, BI; Vesely, P; Hoefler, G; Eichmann, TO; Zimmermann, R; Lass, A Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation.
J BIOL CHEM. 2019; 294(23): 9118-9133. Doi: 10.1074/jbc.RA118.007201 [OPEN ACCESS]
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Fellendorf, FT; Platzer, M; Pilz, R; Rieger, A; Kapfhammer, HP; Mangge, H; Dalkner, N; Zelzer, S; Meinitzer, A; Birner, A; Bengesser, SA; Queissner, R; Hamm, C; Hartleb, R; Reininghaus, EZ Branched-chain amino acids are associated with metabolic parameters in bipolar disorder.
World J Biol Psychiatry. 2018; 1-6 Doi: 10.1080/15622975.2018.1487077
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Hollstein, T; Vogt, A; Grenkowitz, T; Stojakovic, T; März, W; Laufs, U; Bölükbasi, B; Steinhagen-Thiessen, E; Scharnagl, H; Kassner, U Treatment with PCSK9 inhibitors reduces atherogenic VLDL remnants in a real-world study.
Vascul Pharmacol. 2019; 116:8-15 Doi: 10.1016/j.vph.2019.03.002
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Huber, K; Hofer, DC; Trefely, S; Pelzmann, HJ; Madreiter-Sokolowski, C; Duta-Mare, M; Schlager, S; Trausinger, G; Stryeck, S; Graier, WF; Kolb, D; Magnes, C; Snyder, NW; Prokesch, A; Kratky, D; Madl, T; Wellen, KE; Bogner-Strauss, JG N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes.
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Grill, M; Högenauer, C; Blesl, A; Haybaeck, J; Golob-Schwarzl, N; Ferreirós, N; Thomas, D; Gurke, R; Trötzmüller, M; Köfeler, HC; Gallé, B; Schicho, R Members of the endocannabinoid system are distinctly regulated in inflammatory bowel disease and colorectal cancer.
Sci Rep. 2019; 9(1): 2358-2358. Doi: 10.1038/s41598-019-38865-4 [OPEN ACCESS]
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Banach, M; Bruckert, E; Descamps, OS; Ellegård, L; Ezhov, M; Föger, B; Fras, Z; Kovanen, PT; Latkovskis, G; März, W; Panagiotakos, DB; Paragh, G; Pella, D; Pirillo, A; Poli, A; Reiner, Ž; Silbernagel, G; Viigimaa, M; Vrablík, M; Catapano, AL The role of red yeast rice (RYR) supplementation in plasma cholesterol control: A review and expert opinion.
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Scharnagl, H; Stojakovic, T; Dieplinger, B; Dieplinger, H; Erhart, G; Kostner, GM; Herrmann, M; März, W; Grammer, TB Comparison of lipoprotein (a) serum concentrations measured by six commercially available immunoassays.
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Maliković, J; Vuyyuru, H; Koefeler, H; Smidak, R; Höger, H; Kalaba, P; Hussein, AM; Lubec, G; Korz, V Moderate differences in common feeding diets change lipid composition in the hippocampal dentate gyrus and affect spatial cognitive flexibility in male rats.
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Wadsack, D; Sattler, H; Kleber, ME; Eirich, K; Scharnagl, H; Fauler, G; März, W; Grammer, TB Recurrent tendosynovitis as a rare manifestation of a lipid disorder.
J Clin Lipidol. 2019; 13(1): 54-61. Doi: 10.1016/j.jacl.2018.10.005
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Lütjohann, D; Björkhem, I; Friedrichs, S; Kerksiek, A; Lövgren-Sandblom, A; Geilenkeuser, WJ; Ahrends, R; Andrade, I; Ansorena, D; Astiasarán, I; Baila-Rueda, L; Barriuso, B; Becker, S; Bretillon, L; Browne, RW; Caccia, C; Ceglarek, U; Cenarro, A; Crick, PJ; Fauler, G; Garcia-Llatas, G; Gray, R; Griffiths, WJ; Gylling, H; Harding, S; Helmschrodt, C; Iuliano, L; Janssen, HG; Jones, P; Kaipiainen, L; Kannenberg, F; Lagarda, MJ; Leoni, V; Lottenberg, AM; MacKay, DS; Matysik, S; McDonald, J; Menendez-Carreño, M; Myrie, SB; Sutti Nunes, V; Ostlund, RE; Polisecki, E; Ramos, F; Rideout, TC; Schaefer, EJ; Schmitz, G; Wang, Y; Zerbinati, C; Diczfalusy, U; Schött, HF First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography-Urgent need for harmonisation of analytical methods.
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Degoricija, V; Trbušić, M; Potočnjak, I; Radulović, B; Pregartner, G; Berghold, A; Scharnagl, H; Stojakovic, T; Tiran, B; Frank, S Serum concentrations of free fatty acids are associated with 3-month mortality in acute heart failure patients.
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Grill, M; Hasenoehrl, C; Kienzl, M; Kargl, J; Schicho, R Cellular localization and regulation of receptors and enzymes of the endocannabinoid system in intestinal and systemic inflammation.
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Höfer, CT; Di Lella, S; Dahmani, I; Jungnick, N; Bordag, N; Bobone, S; Huang, Q; Keller, S; Herrmann, A; Chiantia, S Structural determinants of the interaction between influenza A virus matrix protein M1 and lipid membranes.
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Gali, CC; Fanaee-Danesh, E; Zandl-Lang, M; Albrecher, NM; Tam-Amersdorfer, C; Stracke, A; Sachdev, V; Reichmann, F; Sun, Y; Avdili, A; Reiter, M; Kratky, D; Holzer, P; Lass, A; Kandimalla, KK; Panzenboeck, U Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice.
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Kiskova, T; Mytsko, Y; Schepelmann, M; Helmer, H; Fuchs, R; Miedl, H; Wadsack, C; Ellinger, I Expression of the neonatal Fc-receptor in placental-fetal endothelium and in cells of the placental immune system.
PLACENTA. 2019; 78(4): 36-43. Doi: 10.1016/j.placenta.2019.02.012
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Kaltenecker, D; Themanns, M; Mueller, KM; Spirk, K; Suske, T; Merkel, O; Kenner, L; Luís, A; Kozlov, A; Haybaeck, J; Müller, M; Han, X; Moriggl, R Hepatic growth hormone - JAK2 - STAT5 signalling: Metabolic function, non-alcoholic fatty liver disease and hepatocellular carcinoma progression.
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Waich, S; Roscher, A; Brunner-Krainz, M; Cortina, G; Köstl, G; Feichtinger, RG; Entenmann, A; Müller, T; Knisely, AS; Mayr, JA; Janecke, AR; Vodopiutz, J Severe Deoxyguanosine Kinase Deficiency in Austria: A 6-Patient Series.
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Safari, Z; Monnoye, M; Abuja, PM; Mariadassou, M; Kashofer, K; Gérard, P; Zatloukal, K Steatosis and gut microbiota dysbiosis induced by high-fat diet are reversed by 1-week chow diet administration.
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Durchschein, F; Eherer, A; Grill, M; Sturm, EM; Pommer, V; Langner, C; Högenauer, C; Schicho, R Involvement of EP2 and EP4 Receptors in Eosinophilic Esophagitis: A Pilot Study.
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Degoricija, V; Potočnjak, I; Gastrager, M; Pregartner, G; Berghold, A; Scharnagl, H; Stojakovic, T; Tiran, B; Marsche, G; Frank, S HDL subclasses and mortality in acute heart failure patients.
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Amor, M; Itariu, BK; Moreno-Viedma, V; Keindl, M; Jürets, A; Prager, G; Langer, F; Grablowitz, V; Zeyda, M; Stulnig, TM Serum Myostatin is Upregulated in Obesity and Correlates with Insulin Resistance in Humans.
EXP CLIN ENDOCR DIAB. 2019; 127(8): 550-556. Doi: 10.1055/a-0641-5546
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Schalli, M; Weber, P; Nasseri, SA; Gomez, AT; Muller, P; Stutz, AE; Withers, SG; Wolfsgruber, A; Wrodnigg, TM Biologically active branched-chain aminocyclopentane tetraols from d-galactose
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Zoidl, M; Wolfsgruber, A; Schalli, M; Nasseri, SA; Weber, P; Stütz, AE; Withers, SG; Wrodnigg, TM Synthesis of modified 1,5-imino-d-xylitols as ligands for lysosomal β-glucocerebrosidase.
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Li, JQ; Gong, JY; Knisely, AS; Zhang, MH; Wang, JS Recurrent acute liver failure associated with novel SCYL1 mutation: A case report
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Hamm, C; Queissner, R; Pilz, R; Birner, A; Platzer, M; Fellendorf, F; Maget, A; Bengesser, S; Dalkner, N; Reininghaus, B; Reininghaus, E [The relationship between intake of lithium and neuroradiological alterations in bipolar disorder. Are there predictors of clinical remission?]
Fortschr Neurol Psychiatr. 2019; 87(9):483-491 Doi: 10.1055/a-0637-1820
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Klec, C; Madreiter-Sokolowski, CT; Stryeck, S; Sachdev, V; Duta-Mare, M; Gottschalk, B; Depaoli, MR; Rost, R; Hay, J; Waldeck-Weiermair, M; Kratky, D; Madl, T; Malli, R; Graier, WF Glycogen Synthase Kinase 3 Beta Controls Presenilin-1-Mediated Endoplasmic Reticulum Ca²⁺ Leak Directed to Mitochondria in Pancreatic Islets and β-Cells.
Cell Physiol Biochem. 2019; 52(1): 57-75. Doi: 10.33594/000000005 [OPEN ACCESS]
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Klec, C; Madreiter-Sokolowski, CT; Ziomek, G; Stryeck, S; Sachdev, V; Duta-Mare, M; Gottschalk, B; Depaoli, MR; Rost, R; Hay, J; Waldeck-Weiermair, M; Kratky, D; Madl, T; Malli, R; Graier, WF Presenilin-1 Established ER-Ca2+ Leak: a Follow Up on Its Importance for the Initial Insulin Secretion in Pancreatic Islets and β-Cells upon Elevated Glucose.
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Liebisch, G; Ahrends, R; Arita, M; Arita, M; Bowden, JA; Ejsing, CS; Griffiths, WJ; Holcapek, M; Kofeler, H; Mitchell, TW; Wenk, MR; Ekroos, K Lipidomics needs more standardization
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Maresch, LK; Benedikt, P; Feiler, U; Eder, S; Zierler, KA; Taschler, U; Kolleritsch, S; Eichmann, TO; Schoiswohl, G; Leopold, C; Wieser, BI; Lackner, C; Rülicke, T; van Klinken, J; Kratky, D; Moustafa, T; Hoefler, G; Haemmerle, G Intestine-Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet-Induced Liver Steatosis and Obesity.
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2018

Kleber, ME; Delgado, GE; Dawczynski, C; Lorkowski, S; März, W Associations of fats and carbohydrates with cardiovascular disease and mortality-PURE and simple?
LANCET. 2018; 391(10131): 1680-1681. Doi: 10.1016/S0140-6736(18)30798-0
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Mach, F; Ray, KK; Wiklund, O; Corsini, A; Catapano, AL; Bruckert, E; De Backer, G; Hegele, RA; Hovingh, GK; Jacobson, TA; Krauss, RM; Laufs, U; Leiter, LA; März, W; Nordestgaard, BG; Raal, FJ; Roden, M; Santos, RD; Stein, EA; Stroes, ES; Thompson, PD; Tokgözoglu, L; Vladutiu, GD; Gencer, B; Stock, JK; Ginsberg, HN; Chapman, MJ; European Atherosclerosis Society Consensus Panel Adverse effects of statin therapy: perception vs. the evidence - focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract.
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Eur J Surg Oncol. 2018; 44(5):658-663 Doi: 10.1016/j.ejso.2018.01.095
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Lütjohann, D; Björkhem, I; Friedrichs, S; Kerksiek, A; Geilenkeuser, WJ; Lövgren-Sandblom, A; Ansorena, D; Astiasarán, I; Baila-Rueda, L; Barriuso, B; Bretillon, L; Browne, RW; Caccia, C; Cenarro, A; Crick, PJ; Fauler, G; García-Llatas, G; Griffiths, WJ; Iuliano, L; Lagarda, MJ; Leoni, V; Lottenberg, AM; Matysik, S; McDonald, J; Rideout, TC; Schmitz, G; Nunes, VS; Wang, Y; Zerbinati, C; Diczfalusy, U; Schött, HF International descriptive and interventional survey for oxycholesterol determination by gas- and liquid-chromatographic methods.
BIOCHIMIE. 2018; 153(3): 26-32. Doi: 10.1016/j.biochi.2018.07.016 [OPEN ACCESS]
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Madreiter-Sokolowski, CT; Sokolowski, AA; Waldeck-Weiermair, M; Malli, R; Graier, WF Targeting Mitochondria to Counteract Age-Related Cellular Dysfunction.
Genes (Basel). 2018; 9(3): Doi: 10.3390/genes9030165 [OPEN ACCESS]
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Koyani, CN; Trummer, C; Shrestha, N; Scheruebel, S; Bourgeois, B; Plastira, I; Kickmaier, S; Sourij, H; Rainer, PP; Madl, T; Sattler, W; Pelzmann, B; Malle, E; von Lewinski, D Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes.
Front Physiol. 2018; 9:1622-1622 Doi: 10.3389/fphys.2018.01622 [OPEN ACCESS]
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Weber, P; Nasseri, SA; Pabst, BM; Torvisco, A; Müller, P; Paschke, E; Tschernutter, M; Windischhofer, W; Withers, SG; Wrodnigg, TM; Stütz, AE Potent GH20 N-Acetyl-β-d-hexosaminidase Inhibitors: N-Substituted 3-acetamido-4-amino-5-hydroxymethyl-cyclopentanediols.
Molecules. 2018; 23(3): 708 Doi: 10.3390/molecules23030708 [OPEN ACCESS]
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Zöhrer, E; Meinel, K; Fauler, G; Moser, VA; Greimel, T; Zobl, J; Schlagenhauf, A; Jahnel, J Neonatal sepsis leads to early rise of rare serum bile acid tauro-omega-muricholic acid (TOMCA).
Pediatr Res. 2018; 84(1):66-70 Doi: 10.1038/s41390-018-0007-y [OPEN ACCESS]
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Scherz, B; Rabl, R; Flunkert, S; Rohler, S; Neddens, J; Taub, N; Temmel, M; Panzenboeck, U; Niederkofler, V; Zimmermann, R; Hutter-Paier, B mTh1 driven expression of hTDP-43 results in typical ALS/FTLD neuropathological symptoms.
PLoS One. 2018; 13(5): e0197674-e0197674. Doi: 10.1371/journal.pone.0197674 [OPEN ACCESS]
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Schaider, M; Novak, T; Komposch, C; Leis, HJ; Raspotnig, G Methyl-ketones in the scent glands of Opiliones: a chemical trait of cyphophthalmi retrieved in the dyspnoan Nemastoma triste.
CHEMOECOLOGY. 2018; 28(2): 61-67. Doi: 10.1007/s00049-018-0257-5 [OPEN ACCESS]
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Contreras-Duarte, S; Chen, P; Andía, M; Uribe, S; Irarrázaval, P; Kopp, S; Kern, S; Marsche, G; Busso, D; Wadsack, C; Rigotti, A Attenuation of atherogenic apo B-48-dependent hyperlipidemia and high density lipoprotein remodeling induced by vitamin C and E combination and their beneficial effect on lethal ischemic heart disease in mice.
Biol Res. 2018; 51(1): 34-34. Doi: 10.1186/s40659-018-0183-6 [OPEN ACCESS]
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2017

Zechner, R; Madeo, F; Kratky, D Cytosolic lipolysis and lipophagy: two sides of the same coin.
Nat Rev Mol Cell Biol. 2017; 18(11):671-684 Doi: 10.1038/nrm.2017.76
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Hartler, J; Triebl, A; Ziegl, A; Trötzmüller, M; Rechberger, GN; Zeleznik, OA; Zierler, KA; Torta, F; Cazenave-Gassiot, A; Wenk, MR; Fauland, A; Wheelock, CE; Armando, AM; Quehenberger, O; Zhang, Q; Wakelam, MJO; Haemmerle, G; Spener, F; Köfeler, HC; Thallinger, GG Deciphering lipid structures based on platform-independent decision rules.
Nat Methods. 2017; 14(12): 1171-1174. Doi: 10.1038/nmeth.4470 [OPEN ACCESS]
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Zewinger, S; Kleber, ME; Rohrer, L; Lehmann, M; Triem, S; Jennings, RT; Petrakis, I; Dressel, A; Lepper, PM; Scharnagl, H; Ritsch, A; Thorand, B; Heier, M; Meisinger, C; de Las Heras Gala, T; Koenig, W; Wagenpfeil, S; Schwedhelm, E; Böger, RH; Laufs, U; von Eckardstein, A; Landmesser, U; Lüscher, TF; Fliser, D; März, W; Meinitzer, A; Speer, T Symmetric dimethylarginine, high-density lipoproteins and cardiovascular disease.
Eur Heart J. 2017; 38(20):1597-1607 Doi: 10.1093/eurheartj/ehx118 [OPEN ACCESS]
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Zewinger, S; Kleber, ME; Tragante, V; McCubrey, RO; Schmidt, AF; Direk, K; Laufs, U; Werner, C; Koenig, W; Rothenbacher, D; Mons, U; Breitling, LP; Brenner, H; Jennings, RT; Petrakis, I; Triem, S; Klug, M; Filips, A; Blankenberg, S; Waldeyer, C; Sinning, C; Schnabel, RB; Lackner, KJ; Vlachopoulou, E; Nygård, O; Svingen, GFT; Pedersen, ER; Tell, GS; Sinisalo, J; Nieminen, MS; Laaksonen, R; Trompet, S; Smit, RAJ; Sattar, N; Jukema, JW; Groesdonk, HV; Delgado, G; Stojakovic, T; Pilbrow, AP; Cameron, VA; Richards, AM; Doughty, RN; Gong, Y; Cooper-DeHoff, R; Johnson, J; Scholz, M; Beutner, F; Thiery, J; Smith, JG; Vilmundarson, RO; McPherson, R; Stewart, AFR; Cresci, S; Lenzini, PA; Spertus, JA; Olivieri, O; Girelli, D; Martinelli, NI; Leiherer, A; Saely, CH; Drexel, H; Mündlein, A; Braund, PS; Nelson, CP; Samani, NJ; Kofink, D; Hoefer, IE; Pasterkamp, G; Quyyumi, AA; Ko, YA; Hartiala, JA; Allayee, H; Tang, WHW; Hazen, SL; Eriksson, N; Held, C; Hagström, E; Wallentin, L; Åkerblom, A; Siegbahn, A; Karp, I; Labos, C; Pilote, L; Engert, JC; Brophy, JM; Thanassoulis, G; Bogaty, P; Szczeklik, W; Kaczor, M; Sanak, M; Virani, SS; Ballantyne, CM; Lee, VV; Boerwinkle, E; Holmes, MV; Horne, BD; Hingorani, A; Asselbergs, FW; Patel, RS; GENIUS-CHD consortium; Krämer, BK; Scharnagl, H; Fliser, D; März, W; Speer, T Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.
Lancet Diabetes Endocrinol. 2017; 5(7):534-543 Doi: 10.1016/S2213-8587(17)30096-7 [OPEN ACCESS]
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Bauer, L; Kern, S; Rogacev, KS; Emrich, IE; Zawada, A; Fliser, D; Heinemann, A; Heine, GH; Marsche, G HDL Cholesterol Efflux Capacity and Cardiovascular Events in Patients With Chronic Kidney Disease.
J Am Coll Cardiol. 2017; 69(2): 246-247. Doi: 10.1016/j.jacc.2016.10.054 [OPEN ACCESS]
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Fickert, P Bad memories from the gut may cause nightmares for the bile ducts.
J Hepatol. 2017; 66(1):5-7 Doi: 10.1016/j.jhep.2016.09.016 [OPEN ACCESS]
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Fickert, P; Hirschfield, GM; Denk, G; Marschall, HU; Altorjay, I; Färkkilä, M; Schramm, C; Spengler, U; Chapman, R; Bergquist, A; Schrumpf, E; Nevens, F; Trivedi, P; Reiter, FP; Tornai, I; Halilbasic, E; Greinwald, R; Pröls, M; Manns, MP; Trauner, M; European PSC norUDCA Study Group norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis.
J Hepatol. 2017; 67(3):549-558 Doi: 10.1016/j.jhep.2017.05.009 [OPEN ACCESS]
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Hanley, J; Dhar, DK; Mazzacuva, F; Fiadeiro, R; Burden, JJ; Lyne, AM; Smith, H; Straatman-Iwanowska, A; Banushi, B; Virasami, A; Mills, K; Lemaigre, FP; Knisely, AS; Howe, S; Sebire, N; Waddington, SN; Paulusma, CC; Clayton, P; Gissen, P Vps33b is crucial for structural and functional hepatocyte polarity.
J Hepatol. 2017; 66(5):1001-1011 Doi: 10.1016/j.jhep.2017.01.001 [OPEN ACCESS]
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Qiu, YL; Gong, JY; Feng, JY; Wang, RX; Han, J; Liu, T; Lu, Y; Li, LT; Zhang, MH; Sheps, JA; Wang, NL; Yan, YY; Li, JQ; Chen, L; Borchers, CH; Sipos, B; Knisely, AS; Ling, V; Xing, QH; Wang, JS Defects in myosin VB are associated with a spectrum of previously undiagnosed low γ-glutamyltransferase cholestasis.
Hepatology. 2017; 65(5):1655-1669 Doi: 10.1002/hep.29020 [OPEN ACCESS]
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Bischof, H; Rehberg, M; Stryeck, S; Artinger, K; Eroglu, E; Waldeck-Weiermair, M; Gottschalk, B; Rost, R; Deak, AT; Niedrist, T; Vujic, N; Lindermuth, H; Prassl, R; Pelzmann, B; Groschner, K; Kratky, D; Eller, K; Rosenkranz, AR; Madl, T; Plesnila, N; Graier, WF; Malli, R Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo.
Nat Commun. 2017; 8(1):1422-1422 Doi: 10.1038/s41467-017-01615-z [OPEN ACCESS]
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Schweiger, M; Romauch, M; Schreiber, R; Grabner, GF; Hütter, S; Kotzbeck, P; Benedikt, P; Eichmann, TO; Yamada, S; Knittelfelder, O; Diwoky, C; Doler, C; Mayer, N; De Cecco, W; Breinbauer, R; Zimmermann, R; Zechner, R Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.
Nat Commun. 2017; 8(5):14859-14859 Doi: 10.1038/ncomms14859 [OPEN ACCESS]
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Grabner, GF; Zimmermann, R; Schicho, R; Taschler, U Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling.
Pharmacol Ther. 2017; 175:35-46 Doi: 10.1016/j.pharmthera.2017.02.033 [OPEN ACCESS]
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Silbernagel, G; Pagel, P; Pfahlert, V; Genser, B; Scharnagl, H; Kleber, ME; Delgado, G; Ohrui, H; Ritsch, A; Grammer, TB; Koenig, W; März, W High-Density Lipoprotein Subclasses, Coronary Artery Disease, and Cardiovascular Mortality.
Clin Chem. 2017; 63(12):1886-1896 Doi: 10.1373/clinchem.2017.275636 [OPEN ACCESS]
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Holzer, M; Trieb, M; Marsche, G The complex high-density lipoprotein proteome: a matter of purification?
Kidney Int. 2017; 92(6): 1555-1555. Doi: 10.1016/j.kint.2017.08.024 [OPEN ACCESS]
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Mueller, KM; Hartmann, K; Kaltenecker, D; Vettorazzi, S; Bauer, M; Mauser, L; Amann, S; Jall, S; Fischer, K; Esterbauer, H; Müller, TD; Tschöp, MH; Magnes, C; Haybaeck, J; Scherer, T; Bordag, N; Tuckermann, JP; Moriggl, R Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition.
Diabetes. 2017; 66(2):272-286 Doi: 10.2337/db16-0381 [OPEN ACCESS]
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Wölkart, G; Schrammel, A; Koyani, CN; Scherübel, S; Zorn-Pauly, K; Malle, E; Pelzmann, B; Andrä, M; Ortner, A; Mayer, B Cardioprotective effects of 5-hydroxymethylfurfural mediated by inhibition of L-type Ca(2+) currents.
Br J Pharmacol. 2017; 174(20):3640-3653 Doi: 10.1111/bph.13967 [OPEN ACCESS]
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Grond, S; Eichmann, TO; Dubrac, S; Kolb, D; Schmuth, M; Fischer, J; Crumrine, D; Elias, PM; Haemmerle, G; Zechner, R; Lass, A; Radner, FPW PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides.
J Invest Dermatol. 2017; 137(2):394-402 Doi: 10.1016/j.jid.2016.08.036 [OPEN ACCESS]
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Grond, S; Radner, FPW; Eichmann, TO; Kolb, D; Grabner, GF; Wolinski, H; Gruber, R; Hofer, P; Heier, C; Schauer, S; Rülicke, T; Hoefler, G; Schmuth, M; Elias, PM; Lass, A; Zechner, R; Haemmerle, G Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation.
J Invest Dermatol. 2017; 137(2):403-413 Doi: 10.1016/j.jid.2016.09.025 [OPEN ACCESS]
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Wu, BJ; Li, Y; Ong, KL; Sun, Y; Shrestha, S; Hou, L; Johns, D; Barter, PJ; Rye, KA Reduction of In-Stent Restenosis by Cholesteryl Ester Transfer Protein Inhibition.
ARTERIOSCL THROM VAS. 2017; 37(12): 2333-2341. Doi: 10.1161/ATVBAHA.117.310051 [OPEN ACCESS]
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Winklhofer-Roob, BM; Faustmann, G; Roob, JM Low-density lipoprotein oxidation biomarkers in human health and disease and effects of bioactive compounds.
Free Radic Biol Med. 2017; 111(5):38-86 Doi: 10.1016/j.freeradbiomed.2017.04.345 [OPEN ACCESS]
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Zietzer, A; Buschmann, EE; Janke, D; Li, L; Brix, M; Meyborg, H; Stawowy, P; Jungk, C; Buschmann, I; Hillmeister, P Acute physical exercise and long-term individual shear rate therapy increase telomerase activity in human peripheral blood mononuclear cells.
Acta Physiol (Oxf). 2017; 220(2): 251-262. Doi: 10.1111/apha.12820
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Marsche, G; Zelzer, S; Meinitzer, A; Kern, S; Meissl, S; Pregartner, G; Weghuber, D; Almer, G; Mangge, H Adiponectin Predicts High-Density Lipoprotein Cholesterol Efflux Capacity in Adults Irrespective of Body Mass Index and Fat Distribution.
J Clin Endocrinol Metab. 2017; 102(11):4117-4123 Doi: 10.1210/jc.2017-00933 [OPEN ACCESS]
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Salminen, A; Vlachopoulou, E; Havulinna, AS; Tervahartiala, T; Sattler, W; Lokki, ML; Nieminen, MS; Perola, M; Salomaa, V; Sinisalo, J; Meri, S; Sorsa, T; Pussinen, PJ Genetic Variants Contributing to Circulating Matrix Metalloproteinase 8 Levels and Their Association With Cardiovascular Diseases: A Genome-Wide Analysis.
Circ Cardiovasc Genet. 2017; 10(6): Doi: 10.1161/CIRCGENETICS.117.001731 [OPEN ACCESS]
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Pessentheiner, AR; Huber, K; Pelzmann, HJ; Prokesch, A; Radner, FPW; Wolinski, H; Lindroos-Christensen, J; Hoefler, G; Rülicke, T; Birner-Gruenberger, R; Bilban, M; Bogner-Strauss, JG APMAP interacts with lysyl oxidase-like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion.
FASEB J. 2017; 31(9):4088-4103 Doi: 10.1096/fj.201601337R [OPEN ACCESS]
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Prokesch, A; Graef, FA; Madl, T; Kahlhofer, J; Heidenreich, S; Schumann, A; Moyschewitz, E; Pristoynik, P; Blaschitz, A; Knauer, M; Muenzner, M; Bogner-Strauss, JG; Dohr, G; Schulz, TJ; Schupp, M Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.
FASEB J. 2017; 31(2):732-742 Doi: 10.1096/fj.201600845R [OPEN ACCESS]
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Graff, M; Scott, RA; Justice, AE; Young, KL; Feitosa, MF; Barata, L; Winkler, TW; Chu, AY; Mahajan, A; Hadley, D; Xue, L; Workalemahu, T; Heard-Costa, NL; den Hoed, M; Ahluwalia, TS; Qi, Q; Ngwa, JS; Renström, F; Quaye, L; Eicher, JD; Hayes, JE; Cornelis, M; Kutalik, Z; Lim, E; Luan, J; Huffman, JE; Zhang, W; Zhao, W; Griffin, PJ; Haller, T; Ahmad, S; Marques-Vidal, PM; Bien, S; Yengo, L; Teumer, A; Smith, AV; Kumari, M; Harder, MN; Justesen, JM; Kleber, ME; Hollensted, M; Lohman, K; Rivera, NV; Whitfield, JB; Zhao, JH; Stringham, HM; Lyytikäinen, LP; Huppertz, C; Willemsen, G; Peyrot, WJ; Wu, Y; Kristiansson, K; Demirkan, A; Fornage, M; Hassinen, M; Bielak, LF; Cadby, G; Tanaka, T; Mägi, R; van der Most, PJ; Jackson, AU; Bragg-Gresham, JL; Vitart, V; Marten, J; Navarro, P; Bellis, C; Pasko, D; Johansson, Å; Snitker, S; Cheng, YC; Eriksson, J; Lim, U; Aadahl, M; Adair, LS; Amin, N; Balkau, B; Auvinen, J; Beilby, J; Bergman, RN; Bergmann, S; Bertoni, AG; Blangero, J; Bonnefond, A; Bonnycastle, LL; Borja, JB; Brage, S; Busonero, F; Buyske, S; Campbell, H; Chines, PS; Collins, FS; Corre, T; Smith, GD; Delgado, GE; Dueker, N; Dörr, M; Ebeling, T; Eiriksdottir, G; Esko, T; Faul, JD; Fu, M; Færch, K; Gieger, C; Gläser, S; Gong, J; Gordon-Larsen, P; Grallert, H; Grammer, TB; Grarup, N; van Grootheest, G; Harald, K; Hastie, ND; Havulinna, AS; Hernandez, D; Hindorff, L; Hocking, LJ; Holmens, OL; Holzapfel, C; Hottenga, JJ; Huang, J; Huang, T; Hui, J; Huth, C; Hutri-Kähönen, N; James, AL; Jansson, JO; Jhun, MA; Juonala, M; Kinnunen, L; Koistinen, HA; Kolcic, I; Komulainen, P; Kuusisto, J; Kvaløy, K; Kähönen, M; Lakka, TA; Launer, LJ; Lehne, B; Lindgren, CM; Lorentzon, M; Luben, R; Marre, M; Milaneschi, Y; Monda, KL; Montgomery, GW; De Moor, MHM; Mulas, A; Müller-Nurasyid, M; Musk, AW; Männikkö, R; Männistö, S; Narisu, N; Nauck, M; Nettleton, JA; Nolte, IM; Oldehinkel, AJ; Olden, M; Ong, KK; Padmanabhan, S; Paternoster, L; Perez, J; Perola, M; Peters, A; Peters, U; Peyser, PA; Prokopenko, I; Puolijoki, H; Raitakari, OT; Rankinen, T; Rasmussen-Torvik, LJ; Rawal, R; Ridker, PM; Rose, LM; Rudan, I; Sarti, C; Sarzynski, MA; Savonen, K; Scott, WR; Sanna, S; Shuldiner, AR; Sidney, S; Silbernagel, G; Smith, BH; Smith, JA; Snieder, H; Stančáková, A; Sternfeld, B; Swift, AJ; Tammelin, T; Tan, ST; Thorand, B; Thuillier, D; Vandenput, L; Vestergaard, H; van Vliet-Ostaptchouk, JV; Vohl, MC; Völker, U; Waeber, G; Walker, M; Wild, S; Wong, A; Wright, AF; Zillikens, MC; Zubair, N; Haiman, CA; Lemarchand, L; Gyllensten, U; Ohlsson, C; Hofman, A; Rivadeneira, F; Uitterlinden, AG; Pérusse, L; Wilson, JF; Hayward, C; Polasek, O; Cucca, F; Hveem, K; Hartman, CA; Tönjes, A; Bandinelli, S; Palmer, LJ; Kardia, SLR; Rauramaa, R; Sørensen, TIA; Tuomilehto, J; Salomaa, V; Penninx, BWJH; de Geus, EJC; Boomsma, DI; Lehtimäki, T; Mangino, M; Laakso, M; Bouchard, C; Martin, NG; Kuh, D; Liu, Y; Linneberg, A; März, W; Strauch, K; Kivimäki, M; Harris, TB; Gudnason, V; Völzke, H; Qi, L; Järvelin, MR; Chambers, JC; Kooner, JS; Froguel, P; Kooperberg, C; Vollenweider, P; Hallmans, G; Hansen, T; Pedersen, O; Metspalu, A; Wareham, NJ; Langenberg, C; Weir, DR; Porteous, DJ; Boerwinkle, E; Chasman, DI; CHARGE Consortium; EPIC-InterAct Consortium; PAGE Consortium; Abecasis, GR; Barroso, I; McCarthy, MI; Frayling, TM; O'Connell, JR; van Duijn, CM; Boehnke, M; Heid, IM; Mohlke, KL; Strachan, DP; Fox, CS; Liu, CT; Hirschhorn, JN; Klein, RJ; Johnson, AD; Borecki, IB; Franks, PW; North, KE; C Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
PLoS Genet. 2017; 13(4): e1006528-e1006528. Doi: 10.1371/journal.pgen.1006528 [OPEN ACCESS]
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Plastira, I; Bernhart, E; Goeritzer, M; DeVaney, T; Reicher, H; Hammer, A; Lohberger, B; Wintersperger, A; Zucol, B; Graier, WF; Kratky, D; Malle, E; Sattler, W Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype.
J Neuroinflammation. 2017; 14(1):253-253 Doi: 10.1186/s12974-017-1024-1 [OPEN ACCESS]
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Schlager, S; Vujic, N; Korbelius, M; Duta-Mare, M; Dorow, J; Leopold, C; Rainer, S; Wegscheider, M; Reicher, H; Ceglarek, U; Sattler, W; Radovic, B; Kratky, D Lysosomal lipid hydrolysis provides substrates for lipid mediator synthesis in murine macrophages.
Oncotarget. 2017; 8(25):40037-40051 Doi: 10.18632/oncotarget.16673 [OPEN ACCESS]
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Vujic, N; Korbelius, M; Leopold, C; Duta-Mare, M; Rainer, S; Schlager, S; Goeritzer, M; Kolb, D; Eichmann, TO; Diwoky, C; Zimmer, A; Zimmermann, R; Lass, A; Radovic, B; Kratky, D Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice.
Oncotarget. 2017; 8(20):33122-33136 Doi: 10.18632/oncotarget.16529 [OPEN ACCESS]
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Hirschmugl, B; Desoye, G; Catalano, P; Klymiuk, I; Scharnagl, H; Payr, S; Kitzinger, E; Schliefsteiner, C; Lang, U; Wadsack, C; Hauguel-de Mouzon, S Maternal obesity modulates intracellular lipid turnover in the human term placenta.
Int J Obes (Lond). 2017; 41(2):317-323 Doi: 10.1038/ijo.2016.188 [OPEN ACCESS]
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Gergei, I; Klotsche, J; Woitas, RP; Pieper, L; Wittchen, HU; Kramer, BK; Wanner, C; Mann, JFE; Scharnagl, H; Marz, W; Mondorf, U Chronic kidney disease in primary care in Germany
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Peinhaupt, M; Sturm, EM; Heinemann, A Prostaglandins and Their Receptors in Eosinophil Function and As Therapeutic Targets.
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Taschler, U; Hasenoehrl, C; Storr, M; Schicho, R Cannabinoid Receptors in Regulating the GI Tract: Experimental Evidence and Therapeutic Relevance.
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Laaksonen, R; Ekroos, K; Sysi-Aho, M; Hilvo, M; Vihervaara, T; Kauhanen, D; Suoniemi, M; Hurme, R; März, W; Scharnagl, H; Stojakovic, T; Vlachopoulou, E; Lokki, ML; Nieminen, MS; Klingenberg, R; Matter, CM; Hornemann, T; Jüni, P; Rodondi, N; Räber, L; Windecker, S; Gencer, B; Pedersen, ER; Tell, GS; Nygård, O; Mach, F; Sinisalo, J; Lüscher, TF Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol.
Eur Heart J. 2016; 37(25):1967-1976 Doi: 10.1093/eurheartj/ehw148 [OPEN ACCESS]
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März, W; Ritsch, A Cholesterol Efflux Capacity: Choke Point of Reverse Cholesterol Traffic?
J Am Coll Cardiol. 2016; 67(21):2488-2491 Doi: 10.1016/j.jacc.2016.04.005 [OPEN ACCESS]
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Krones, E; Wagner, M Fibroblast growth factor 19 meets mammalian target of rapamycin: A mitogenic Tête-à-Tête under consideration.
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Wagner, M; Choi, S; Panzitt, K; Mamrosh, JL; Lee, JM; Zaufel, A; Xiao, R; Wooton-Kee, R; Ståhlman, M; Newgard, CB; Borén, J; Moore, DD Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism.
Hepatology. 2016; 63(1):95-106 Doi: 10.1002/hep.28124 [OPEN ACCESS]
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Wagner, M; Fickert, P; Zollner, G Secretin and cholestasis, two sides of a coin.
Hepatology. 2016; 64(3):714-716 Doi: 10.1002/hep.28687 [OPEN ACCESS]
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Jandl, K; Stacher, E; Bálint, Z; Sturm, EM; Maric, J; Peinhaupt, M; Luschnig, P; Aringer, I; Fauland, A; Konya, V; Dahlen, SE; Wheelock, CE; Kratky, D; Olschewski, A; Marsche, G; Schuligoi, R; Heinemann, A Activated prostaglandin D2 receptors on macrophages enhance neutrophil recruitment into the lung.
J Allergy Clin Immunol. 2016; 137(3):833-843 Doi: 10.1016/j.jaci.2015.11.012 [OPEN ACCESS]
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Bartuzi, P; Billadeau, DD; Favier, R; Rong, S; Dekker, D; Fedoseienko, A; Fieten, H; Wijers, M; Levels, JH; Huijkman, N; Kloosterhuis, N; van der Molen, H; Brufau, G; Groen, AK; Elliott, AM; Kuivenhoven, JA; Plecko, B; Grangl, G; McGaughran, J; Horton, JD; Burstein, E; Hofker, MH; van de Sluis, B CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.
Nat Commun. 2016; 7(5):10961-10961 Doi: 10.1038/ncomms10961 [OPEN ACCESS]
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Eroglu, E; Gottschalk, B; Charoensin, S; Blass, S; Bischof, H; Rost, R; Madreiter-Sokolowski, CT; Pelzmann, B; Bernhart, E; Sattler, W; Hallström, S; Malinski, T; Waldeck-Weiermair, M; Graier, WF; Malli, R Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics.
Nat Commun. 2016; 7(3):10623-10623 Doi: 10.1038/ncomms10623 [OPEN ACCESS]
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Roier, S; Zingl, FG; Cakar, F; Durakovic, S; Kohl, P; Eichmann, TO; Klug, L; Gadermaier, B; Weinzerl, K; Prassl, R; Lass, A; Daum, G; Reidl, J; Feldman, MF; Schild, S A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria.
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Diabetes. 2016; 65(10):3200-3211 Doi: 10.2337/db16-0199 [OPEN ACCESS]
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Klionsky, DJ; Abdelmohsen, K; Abe, A; Abedin, MJ; Abeliovich, H; Acevedo Arozena, A; Adachi, H; Adams, CM; Adams, PD; Adeli, K; Adhihetty, PJ; Adler, SG; Agam, G; Agarwal, R; ... Malli, R; ... Sedej, S; ... et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
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Krane, V; Schmidt, KR; Gutjahr-Lengsfeld, LJ; Mann, JF; März, W; Swoboda, F; Wanner, C; 4D Study Investigators (the German Diabetes and Dialysis Study Investigators) Long-term effects following 4 years of randomized treatment with atorvastatin in patients with type 2 diabetes mellitus on hemodialysis.
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Huang, J; Li, L; Lian, J; Schauer, S; Vesely, PW; Kratky, D; Hoefler, G; Lehner, R Tumor-Induced Hyperlipidemia Contributes to Tumor Growth.
Cell Rep. 2016; 15(2): 336-348. Doi: 10.1016/j.celrep.2016.03.020 [OPEN ACCESS]
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Frei, RB; Luschnig, P; Parzmair, GP; Peinhaupt, M; Schranz, S; Fauland, A; Wheelock, CE; Heinemann, A; Sturm, EM Cannabinoid receptor 2 augments eosinophil responsiveness and aggravates allergen-induced pulmonary inflammation in mice.
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Derler, I; Jardin, I; Stathopulos, PB; Muik, M; Fahrner, M; Zayats, V; Pandey, SK; Poteser, M; Lackner, B; Absolonova, M; Schindl, R; Groschner, K; Ettrich, R; Ikura, M; Romanin, C Cholesterol modulates Orai1 channel function.
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Giroud, M; Pisani, DF; Karbiener, M; Barquissau, V; Ghandour, RA; Tews, D; Fischer-Posovszky, P; Chambard, JC; Knippschild, U; Niemi, T; Taittonen, M; Nuutila, P; Wabitsch, M; Herzig, S; Virtanen, KA; Langin, D; Scheideler, M; Amri, EZ miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function.
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Tardelli, M; Zeyda, K; Moreno-Viedma, V; Wanko, B; Grün, NG; Staffler, G; Zeyda, M; Stulnig, TM Osteopontin is a key player for local adipose tissue macrophage proliferation in obesity.
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Roeseler, E; Julius, U; Heigl, F; Spitthoever, R; Heutling, D; Breitenberger, P; Leebmann, J; Lehmacher, W; Kamstrup, PR; Nordestgaard, BG; Maerz, W; Noureen, A; Schmidt, K; Kronenberg, F; Heibges, A; Klingel, R; Pro(a)LiFe-Study Group Lipoprotein Apheresis for Lipoprotein(a)-Associated Cardiovascular Disease: Prospective 5 Years of Follow-Up and Apolipoprotein(a) Characterization.
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Radović, B; Vujić, N; Leopold, C; Schlager, S; Goeritzer, M; Patankar, JV; Korbelius, M; Kolb, D; Reindl, J; Wegscheider, M; Tomin, T; Birner-Gruenberger, R; Schittmayer, M; Groschner, L; Magnes, C; Diwoky, C; Frank, S; Steyrer, E; Du, H; Graier, WF; Madl, T; Kratky, D Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice.
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Radnai, B; Sturm, EM; Stančić, A; Jandl, K; Labocha, S; Ferreirós, N; Grill, M; Hasenoehrl, C; Gorkiewicz, G; Marsche, G; Heinemann, Á; Högenauer, C; Schicho, R Eosinophils Contribute to Intestinal Inflammation via Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells, CRTH2, in Experimental Crohn's Disease.
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Nusshold, C; Üllen, A; Kogelnik, N; Bernhart, E; Reicher, H; Plastira, I; Glasnov, T; Zangger, K; Rechberger, G; Kollroser, M; Fauler, G; Wolinski, H; Weksler, BB; Romero, IA; Kohlwein, SD; Couraud, PO; Malle, E; Sattler, W Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analog of 2-chlorohexadecanal.
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Aschauer, P; Rengachari, S; Lichtenegger, J; Schittmayer, M; Das, KM; Mayer, N; Breinbauer, R; Birner-Gruenberger, R; Gruber, CC; Zimmermann, R; Gruber, K; Oberer, M Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p.
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Sachdev, V; Leopold, C; Bauer, R; Patankar, JV; Iqbal, J; Obrowsky, S; Boverhof, R; Doktorova, M; Scheicher, B; Goeritzer, M; Kolb, D; Turnbull, AV; Zimmer, A; Hoefler, G; Hussain, MM; Groen, AK; Kratky, D Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.
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Trieb, M; Horvath, A; Birner-Gruenberger, R; Spindelboeck, W; Stadlbauer, V; Taschler, U; Curcic, S; Stauber, RE; Holzer, M; Pasterk, L; Heinemann, A; Marsche, G Liver disease alters high-density lipoprotein composition, metabolism and function.
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Kargl, J; Andersen, L; Hasenöhrl, C; Feuersinger, D; Stančić, A; Fauland, A; Magnes, C; El-Heliebi, A; Lax, S; Uranitsch, S; Haybaeck, J; Heinemann, A; Schicho, R GPR55 promotes migration and adhesion of colon cancer cells indicating a role in metastasis.
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Koyani, CN; Kitz, K; Rossmann, C; Bernhart, E; Huber, E; Trummer, C; Windischhofer, W; Sattler, W; Malle, E Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death.
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Leis, HJ; Windischhofer, W Calcium-independent phospholipases A2 in murine osteoblastic cells and their inhibition by bromoenol lactone: impact on arachidonate dynamics and prostaglandin synthesis.
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Holzer, M; Kern, S; Birner-Grünberger, R; Curcic, S; Heinemann, A; Marsche, G Refined purification strategy for reliable proteomic profiling of HDL2/3: Impact on proteomic complexity.
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Themanns, M; Mueller, KM; Kessler, SM; Golob-Schwarzl, N; Mohr, T; Kaltenecker, D; Bourgeais, J; Paier-Pourani, J; Friedbichler, K; Schneller, D; Schlederer, M; Zebedin-Brandl, E; Terracciano, LM; Han, X; Kenner, L; Wagner, KU; Mikulits, W; Kozlov, AV; Heim, MH; Gouilleux, F; Haybaeck, J; Moriggl, R Hepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice.
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Grenkowitz, T; Kassner, U; Wühle-Demuth, M; Salewsky, B; Rosada, A; Zemojtel, T; Hopfenmüller, W; Isermann, B; Borucki, K; Heigl, F; Laufs, U; Wagner, S; Kleber, ME; Binner, P; März, W; Steinhagen-Thiessen, E; Demuth, I Clinical characterization and mutation spectrum of German patients with familial hypercholesterolemia.
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Kleber, ME; Delgado, GE; Lorkowski, S; März, W; von Schacky, C Omega-3 fatty acids and mortality in patients referred for coronary angiography. The Ludwigshafen Risk and Cardiovascular Health Study.
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Vujic, N; Schlager, S; Eichmann, TO; Madreiter-Sokolowski, CT; Goeritzer, M; Rainer, S; Schauer, S; Rosenberger, A; Woelfler, A; Doddapattar, P; Zimmermann, R; Hoefler, G; Lass, A; Graier, WF; Radovic, B; Kratky, D Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice.
Atherosclerosis. 2016; 244(3):9-21 Doi: 10.1016/j.atherosclerosis.2015.10.109 [OPEN ACCESS]
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Vinod, M; Patankar, JV; Sachdev, V; Frank, S; Graier, WF; Kratky, D; Kostner, GM MiR-206 is expressed in pancreatic islets and regulates glucokinase activity.
Am J Physiol Endocrinol Metab. 2016; 311(1):E175-E185 Doi: 10.1152/ajpendo.00510.2015 [OPEN ACCESS]
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Kessler, SM; Laggai, S; Van Wonterg, E; Gemperlein, K; Müller, R; Haybaeck, J; Vandenbroucke, RE; Ogris, M; Libert, C; Kiemer, AK Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation.
Front Physiol. 2016; 7(9):147-147 Doi: 10.3389/fphys.2016.00147 [OPEN ACCESS]
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Grumet, L; Eichmann, TO; Taschler, U; Zierler, KA; Leopold, C; Moustafa, T; Radovic, B; Romauch, M; Yan, C; Du, H; Haemmerle, G; Zechner, R; Fickert, P; Kratky, D; Zimmermann, R; Lass, A Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover.
J Biol Chem. 2016; 291(34):17977-17987 Doi: 10.1074/jbc.M116.724054 [OPEN ACCESS]
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Kawala, MA; Bohndorf, M; Graffmann, N; Wruck, W; Zatloukal, K; Adjaye, J Characterization of dermal fibroblast-derived iPSCs from a patient with high grade steatosis.
Stem Cell Res. 2016; 17(3):568-571 Doi: 10.1016/j.scr.2016.10.007 [OPEN ACCESS]
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Kawala, MA; Bohndorf, M; Graffmann, N; Wruck, W; Zatloukal, K; Adjaye, J Characterization of dermal fibroblast-derived iPSCs from a patient with low grade steatosis.
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Kawala, MA; Bohndorf, M; Graffmann, N; Wruck, W; Zatloukal, K; Adjaye, J Characterization of iPSCs derived from dermal fibroblasts from a healthy 19year old female.
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Tomazic, PV; Birner-Gruenberger, R; Leitner, A; Spoerk, S; Lang-Loidolt, D Seasonal proteome changes of nasal mucus reflect perennial inflammatory response and reduced defence mechanisms and plasticity in allergic rhinitis.
J Proteomics. 2016; 133(4):153-160 Doi: 10.1016/j.jprot.2015.12.021 [OPEN ACCESS]
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Schuch, K; Wanko, B; Ambroz, K; Castelo-Rosa, A; Moreno-Viedma, V; Grün, NG; Leitner, L; Staffler, G; Zeyda, M; Stulnig, TM Osteopontin affects macrophage polarization promoting endocytic but not inflammatory properties.
Obesity (Silver Spring). 2016; 24(7):1489-1498 Doi: 10.1002/oby.21510 [OPEN ACCESS]
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Theiler, A; Konya, V; Pasterk, L; Maric, J; Bärnthaler, T; Lanz, I; Platzer, W; Schuligoi, R; Heinemann, A The EP1/EP3 receptor agonist 17-pt-PGE2 acts as an EP4 receptor agonist on endothelial barrier function and in a model of LPS-induced pulmonary inflammation.
Vascul Pharmacol. 2016; 87(4):180-189 Doi: 10.1016/j.vph.2016.09.008 [OPEN ACCESS]
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Svobodova, B; Groschner, K Mechanisms of lipid regulation and lipid gating in TRPC channels.
Cell Calcium. 2016; 59(6):271-279 Doi: 10.1016/j.ceca.2016.03.012 [OPEN ACCESS]
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Hasenoehrl, C; Taschler, U; Storr, M; Schicho, R The gastrointestinal tract - a central organ of cannabinoid signaling in health and disease.
Neurogastroenterol Motil. 2016; 28(12):1765-1780 Doi: 10.1111/nmo.12931 [OPEN ACCESS]
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Gouni-Berthold, I; Descamps, OS; Fraass, U; Hartfield, E; Allcott, K; Dent, R; März, W Systematic review of published Phase 3 data on anti-PCSK9 monoclonal antibodies in patients with hypercholesterolaemia.
Br J Clin Pharmacol. 2016; 82(6):1412-1443 Doi: 10.1111/bcp.13066 [OPEN ACCESS]
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Hartmann, P; Seebauer, CT; Mazagova, M; Horvath, A; Wang, L; Llorente, C; Varki, NM; Brandl, K; Ho, SB; Schnabl, B Deficiency of intestinal mucin-2 protects mice from diet-induced fatty liver disease and obesity.
Am J Physiol Gastrointest Liver Physiol. 2016; 310(5):G310-G322 Doi: 10.1152/ajpgi.00094.2015 [OPEN ACCESS]
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Reiter, FP; Wimmer, R; Wottke, L; Artmann, R; Nagel, JM; Carranza, MO; Mayr, D; Rust, C; Fickert, P; Trauner, M; Gerbes, AL; Hohenester, S; Denk, GU Role of interleukin-1 and its antagonism of hepatic stellate cell proliferation and liver fibrosis in the Abcb4(-/-) mouse model.
World J Hepatol. 2016; 8(8):401-410 Doi: 10.4254/wjh.v8.i8.401 [OPEN ACCESS]
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Tang, Y; Fickert, P; Trauner, M; Marcus, N; Blomenkamp, K; Teckman, J Autophagy induced by exogenous bile acids is therapeutic in a model of α-1-AT deficiency liver disease.
Am J Physiol Gastrointest Liver Physiol. 2016; 311(1):G156-G165 Doi: 10.1152/ajpgi.00143.2015 [OPEN ACCESS]
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Rezania, S; Kammerer, S; Li, C; Steinecker-Frohnwieser, B; Gorischek, A; DeVaney, TT; Verheyen, S; Passegger, CA; Tabrizi-Wizsy, NG; Hackl, H; Platzer, D; Zarnani, AH; Malle, E; Jahn, SW; Bauernhofer, T; Schreibmayer, W Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner.
BMC Cancer. 2016; 16(1):628-628 Doi: 10.1186/s12885-016-2664-8 [OPEN ACCESS]
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Leis, HJ; Windischhofer, W Potentiation of endothelin-1-induced prostaglandin E2 formation by Ni(2+) and Sr(2+) in murine osteoblastic MC3T3-E1 cells.
J Trace Elem Med Biol. 2016; 33(3):81-86 Doi: 10.1016/j.jtemb.2015.10.001
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Besenboeck, C; Cvitic, S; Lang, U; Desoye, G; Wadsack, C Going into labor and beyond: phospholipase A2 in pregnancy.
Reproduction. 2016; 151(6):R91-R102 Doi: 10.1530/REP-15-0519 [OPEN ACCESS]
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Konya, V; Mjösberg, J Lipid mediators as regulators of human ILC2 function in allergic diseases.
Immunol Lett. 2016; 179:36-42 Doi: 10.1016/j.imlet.2016.07.006 [OPEN ACCESS]
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Birner-Gruenberger, R; Breinbauer, R Tracking Protein S-Fatty Acylation with Proteomics.
Chembiochem. 2016; 17(16):1488-1490 Doi: 10.1002/cbic.201600314
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Fengler, VH; Macheiner, T; Kessler, SM; Czepukojc, B; Gemperlein, K; Müller, R; Kiemer, AK; Magnes, C; Haybaeck, J; Lackner, C; Sargsyan, K Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease.
PLoS One. 2016; 11(5):e0155163-e0155163 Doi: 10.1371/journal.pone.0155163 [OPEN ACCESS]
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Lipovšek, S; Novak, T; Janžekovič, F; Weiland, N; Leitinger, G Malpighian Tubule Cells in Overwintering Cave Crickets Troglophilus cavicola (Kollar, 1833) and T. neglectus Krauss, 1879 (Rhaphidophoridae, Ensifera).
PLoS One. 2016; 11(7):e0158598-e0158598 Doi: 10.1371/journal.pone.0158598 [OPEN ACCESS]
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Pertl, L; Kern, S; Weger, M; Hausberger, S; Trieb, M; Gasser-Steiner, V; Haas, A; Scharnagl, H; Heinemann, A; Marsche, G High-Density Lipoprotein Function in Exudative Age-Related Macular Degeneration.
PLoS One. 2016; 11(5):e0154397-e0154397 Doi: 10.1371/journal.pone.0154397 [OPEN ACCESS]
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Potočnjak, I; Degoricija, V; Trbušić, M; Terešak, SD; Radulović, B; Pregartner, G; Berghold, A; Tiran, B; Marsche, G; Frank, S Metrics of High-Density Lipoprotein Function and Hospital Mortality in Acute Heart Failure Patients.
PLoS One. 2016; 11(6):e0157507-e0157507 Doi: 10.1371/journal.pone.0157507 [OPEN ACCESS]
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Rogacev, KS; Heine, GH; Silbernagel, G; Kleber, ME; Seiler, S; Emrich, I; Lennartz, S; Werner, C; Zawada, AM; Fliser, D; Böhm, M; März, W; Scharnagl, H; Laufs, U PCSK9 Plasma Concentrations Are Independent of GFR and Do Not Predict Cardiovascular Events in Patients with Decreased GFR.
PLoS One. 2016; 11(1):e0146920-e0146920 Doi: 10.1371/journal.pone.0146920 [OPEN ACCESS]
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Vujic, N; Porter Abate, J; Schlager, S; David, T; Kratky, D; Koliwad, SK Acyl-CoA:Diacylglycerol Acyltransferase 1 Expression Level in the Hematopoietic Compartment Impacts Inflammation in the Vascular Plaques of Atherosclerotic Mice.
PLoS One. 2016; 11(5):e0156364-e0156364 Doi: 10.1371/journal.pone.0156364 [OPEN ACCESS]
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Klapper, M; Findeis, D; Koefeler, H; Döring, F Methyl group donors abrogate adaptive responses to dietary restriction in C. elegans.
Genes Nutr. 2016; 11(6):4-4 Doi: 10.1186/s12263-016-0522-4 [OPEN ACCESS]
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Tiapko, O; Bacsa, B; de la Cruz, GG; Glasnov, T; Groschner, K Optopharmacological control of TRPC channels by coumarin-caged lipids is associated with a phototoxic membrane effect.
Sci China Life Sci. 2016; 59(8):802-810 Doi: 10.1007/s11427-016-5095-5 [OPEN ACCESS]
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März, W; Scharnagl, H; Gouni-Berthold, I; Silbernagel, G; Dressel, A; Grammer, TB; Landmesser, U; Dieplinger, H; Windler, E; Laufs, U LDL-Cholesterol: Standards of Treatment 2016: A German Perspective.
Am J Cardiovasc Drugs. 2016; 16(5):323-336 Doi: 10.1007/s40256-016-0179-y [OPEN ACCESS]
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Albrecht, C; Caniggia, I; Clifton, V; Göhner, C; Harris, L; Hemmings, D; Jawerbaum, A; Johnstone, E; Jones, H; Keelan, J; Lewis, R; Mitchell, M; Murthi, P; Powell, T; Saffery, R; Smith, R; Vaillancourt, C; Wadsack, C; Salomon, C IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid.
Placenta. 2016; 48 Suppl 1(2):S12-S16 Doi: 10.1016/j.placenta.2016.01.003
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Kessler, SM; Haybaeck, J; Kiemer, AK Insulin-Like Growth Factor 2 - The Oncogene and its Accomplices.
Curr Pharm Des. 2016; 22(39):5948-5961 Doi: 10.2174/1381612822666160713100235
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Triebl, A; Weissengruber, S; Trötzmüller, M; Lankmayr, E; Köfeler, H Quantitative analysis of N-acylphosphatidylethanolamine molecular species in rat brain using solid-phase extraction combined with reversed-phase chromatography and tandem mass spectrometry.
J Sep Sci. 2016; 39(13):2474-2480 Doi: 10.1002/jssc.201600172 [OPEN ACCESS]
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Thonhofer, M; Weber, P; Santana, AG; Fischer, R; Pabst, BM; Paschke, E; Schalli, M; Stütz, AE; Tschernutter, M; Windischhofer, W; Withers, SG Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerful β-galactosidase inhibitors and low concentration activators of GM1-gangliosidosis-related human lysosomal β-galactosidase.
Bioorg Med Chem Lett. 2016; 26(5):1438-1442 Doi: 10.1016/j.bmcl.2016.01.059
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Gaggl, M; Lajic, N; Heinze, G; Voigtländer, T; Sunder-Plassmann, R; Paschke, E; Fauler, G; Sunder-Plassmann, G; Mundigler, G Screening for Fabry Disease by Urinary Globotriaosylceramide Isoforms Measurement in Patients with Left Ventricular Hypertrophy.
Int J Med Sci. 2016; 13(5):340-346 Doi: 10.7150/ijms.14997 [OPEN ACCESS]
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Bodner, M; Vagalinski, B; Makarov, SE; Antić, DŽ; Vujisić, LV; Leis, HJ; Raspotnig, G "Quinone Millipedes" Reconsidered: Evidence for a Mosaic-Like Taxonomic Distribution of Phenol-Based Secretions across the Julidae.
J Chem Ecol. 2016; 42(3):249-258 Doi: 10.1007/s10886-016-0680-4 [OPEN ACCESS]
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Alfakry, H; Malle, E; Koyani, CN; Pussinen, PJ; Sorsa, T Neutrophil proteolytic activation cascades: a possible mechanistic link between chronic periodontitis and coronary heart disease.
Innate Immun. 2016; 22(1):85-99 Doi: 10.1177/1753425915617521 [OPEN ACCESS]
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Enko, D; Meinitzer, A; Mangge, H; Kriegshäuser, G; Halwachs-Baumann, G; Reininghaus, EZ; Bengesser, SA; Schnedl, WJ Concomitant Prevalence of Low Serum Diamine Oxidase Activity and Carbohydrate Malabsorption.
Can J Gastroenterol Hepatol. 2016; 2016(2):4893501-4893501 Doi: 10.1155/2016/4893501 [OPEN ACCESS]
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Thonhofer, M; Gonzalez Santana, A; Fischer, R; Torvisco Gomez, A; Saf, R; Schalli, M; Stütz, AE; Withers, SG 5-Fluoro derivatives of 4-epi-isofagomine as D-galactosidase inhibitors and potential pharmacological chaperones for GM1-gangliosidosis as well as Fabry's disease.
Carbohydr Res. 2016; 420(5): 6-12. Doi: 10.1016/j.carres.2015.10.009
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Thonhofer, M; Weber, P; Gonzalez Santana, A; Tysoe, C; Fischer, R; Pabst, BM; Paschke, E; Schalli, M; Stütz, AE; Tschernutter, M; Windischhofer, W; Withers, SG Synthesis of C-5a-substituted derivatives of 4-epi-isofagomine: notable β-galactosidase inhibitors and activity promotors of GM1-gangliosidosis related human lysosomal β-galactosidase mutant R201C.
Carbohydr Res. 2016; 429(15):71-80 Doi: 10.1016/j.carres.2016.03.020
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Stumptner, C; Gogg-Kamerer, M; Viertler, C; Denk, H; Zatloukal, K Immunofluorescence and Immunohistochemical Detection of Keratins.
Methods Enzymol. 2016; 568:139-162 Doi: 10.1016/bs.mie.2015.08.003
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Rossberg, W; Saternus, R; Wagenpfeil, S; Kleber, M; März, W; Reichrath, S; Vogt, T; Reichrath, J Human Pigmentation, Cutaneous Vitamin D Synthesis and Evolution: Variants of Genes (SNPs) Involved in Skin Pigmentation Are Associated with 25(OH)D Serum Concentration.
Anticancer Res. 2016; 36(3):1429-1437
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Leis, HJ; Windischhofer, W Ionomycin induces prostaglandin E2 formation in murine osteoblastic MC3T3-E1 cells via mechanisms independent of its ionophoric nature.
Biochem Cell Biol. 2016; 94(3):236-240 Doi: 10.1139/bcb-2015-0148 [OPEN ACCESS]
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Zöhrer, E; Resch, B; Scharnagl, H; Schlagenhauf, A; Fauler, G; Stojakovic, T; Hofer, N; Lang, U; Jahnel, J Serum bile acids in term and preterm neonates: A case-control study determining reference values and the influence of early-onset sepsis.
Medicine (Baltimore). 2016; 95(44):e5219-e5219 Doi: 10.1097/MD.0000000000005219 [OPEN ACCESS]
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Grammer, T; Kleber, M; Silbernagel, G; Scharnagl, H; März, W [Residual risk: The roles of triglycerides and high density lipoproteins].
Dtsch Med Wochenschr. 2016; 141(12):870-877 Doi: 10.1055/s-0042-104049
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Herrera, E; Desoye, G Maternal and fetal lipid metabolism under normal and gestational diabetic conditions.
Horm Mol Biol Clin Investig. 2016; 26(2):109-127 Doi: 10.1515/hmbci-2015-0025 [OPEN ACCESS]
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Mangge, H Beyond Cholesterol - New Cardiovascular Biomarkers.
Nestle Nutr Inst Workshop Ser. 2016; 84: 81-88. Doi: 10.1159/000436990
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Sarosiek, I; Schicho, R; Blandon, P; Bashashati, M Urinary metabolites as noninvasive biomarkers of gastrointestinal diseases: A clinical review.
World J Gastrointest Oncol. 2016; 8(5):459-465 Doi: 10.4251/wjgo.v8.i5.459 [OPEN ACCESS]
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Wagner, M; Trauner, M Recent advances in understanding and managing cholestasis.
F1000Res. 2016; 5(8): Doi: 10.12688/f1000research.8012.1 [OPEN ACCESS]
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2015

Silbernagel, G; Baumgartner, I; März, W Ezetimibe plus a Statin after Acute Coronary Syndromes.
N Engl J Med. 2015; 373(15):1473-1473 Doi: 10.1056/NEJMc1509363#SA1 [OPEN ACCESS]
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Silbernagel, G; Baumgartner, I; März, W Mutations in NPC1L1 and coronary heart disease.
N Engl J Med. 2015; 372(9):882-882 Doi: 10.1056/NEJMc1500124#SA3 [OPEN ACCESS]
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Do, R; Stitziel, NO; Won, HH; Jørgensen, AB; Duga, S; Angelica Merlini, P; Kiezun, A; Farrall, M; Goel, A; Zuk, O; Guella, I; Asselta, R; Lange, LA; Peloso, GM; Auer, PL; NHLBI Exome Sequencing Project; Girelli, D; Martinelli, N; Farlow, DN; DePristo, MA; Roberts, R; Stewart, AF; Saleheen, D; Danesh, J; Epstein, SE; Sivapalaratnam, S; Hovingh, GK; Kastelein, JJ; Samani, NJ; Schunkert, H; Erdmann, J; Shah, SH; Kraus, WE; Davies, R; Nikpay, M; Johansen, CT; Wang, J; Hegele, RA; Hechter, E; Marz, W; Kleber, ME; Huang, J; Johnson, AD; Li, M; Burke, GL; Gross, M; Liu, Y; Assimes, TL; Heiss, G; Lange, EM; Folsom, AR; Taylor, HA; Olivieri, O; Hamsten, A; Clarke, R; Reilly, DF; Yin, W; Rivas, MA; Donnelly, P; Rossouw, JE; Psaty, BM; Herrington, DM; Wilson, JG; Rich, SS; Bamshad, MJ; Tracy, RP; Cupples, LA; Rader, DJ; Reilly, MP; Spertus, JA; Cresci, S; Hartiala, J; Tang, WH; Hazen, SL; Allayee, H; Reiner, AP; Carlson, CS; Kooperberg, C; Jackson, RD; Boerwinkle, E; Lander, ES; Schwartz, SM; Siscovick, DS; McPherson, R; Tybjaerg-Hansen, A; Abecasis, GR; Watkins, H; Nickerson, DA; Ardissino, D; Sunyaev, SR; O'Donnell, CJ; Altshuler, D; Gabriel, S; Kathiresan, S Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.
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Parwani, AS; von Haehling, S; Kolodziejski, AI; Huemer, M; Wutzler, A; Attanasio, P; Stojakovic, T; Scharnagl, H; Haverkamp, W; Boldt, LH Mid-regional proadrenomedullin levels predict recurrence of atrial fibrillation after catheter ablation.
Int J Cardiol. 2015; 180(5):129-133 Doi: 10.1016/j.ijcard.2014.11.117
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Kassner, U; Salewsky, B; Wühle-Demuth, M; Szijarto, IA; Grenkowitz, T; Binner, P; März, W; Steinhagen-Thiessen, E; Demuth, I Severe hypertriglyceridemia in a patient heterozygous for a lipoprotein lipase gene allele with two novel missense variants.
Eur J Hum Genet. 2015; 23(9):1259-1261 Doi: 10.1038/ejhg.2014.295 (- Case Report) [OPEN ACCESS]
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Sahu-Osen, A; Montero-Moran, G; Schittmayer, M; Fritz, K; Dinh, A; Chang, YF; McMahon, D; Boeszoermenyi, A; Cornaciu, I; Russell, D; Oberer, M; Carman, GM; Birner-Gruenberger, R; Brasaemle, DL CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization.
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Marsche, G It's Time to Reassess the High-Density Lipoprotein (HDL) Hypothesis: CSL112, a Novel Promising Reconstituted HDL Formulation.
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Marsche, G Lp-PLA2, plaque inflammation and lesion development vary fundamentally between different vascular sites.
J Am Heart Assoc. 2015; 4(2): Doi: 10.1161/JAHA.115.001800 [OPEN ACCESS]
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Heier, C; Radner, FP; Moustafa, T; Schreiber, R; Grond, S; Eichmann, TO; Schweiger, M; Schmidt, A; Cerk, IK; Oberer, M; Theussl, HC; Wojciechowski, J; Penninger, JM; Zimmermann, R; Zechner, R G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis.
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Hofer, P; Boeszoermenyi, A; Jaeger, D; Feiler, U; Arthanari, H; Mayer, N; Zehender, F; Rechberger, G; Oberer, M; Zimmermann, R; Lass, A; Haemmerle, G; Breinbauer, R; Zechner, R; Preiss-Landl, K Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling.
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Pribasnig, MA; Mrak, I; Grabner, GF; Taschler, U; Knittelfelder, O; Scherz, B; Eichmann, TO; Heier, C; Grumet, L; Kowaliuk, J; Romauch, M; Holler, S; Anderl, F; Wolinski, H; Lass, A; Breinbauer, R; Marsche, G; Brown, JM; Zimmermann, R α/β Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate.
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Sturm, EM; Parzmair, GP; Radnai, B; Frei, RB; Sturm, GJ; Hammer, A; Schuligoi, R; Lippe, IT; Heinemann, A Phosphoinositide-dependent protein kinase 1 (PDK1) mediates potent inhibitory effects on eosinophils.
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Schlager, S; Goeritzer, M; Jandl, K; Frei, R; Vujic, N; Kolb, D; Strohmaier, H; Dorow, J; Eichmann, TO; Rosenberger, A; Wölfler, A; Lass, A; Kershaw, EE; Ceglarek, U; Dichlberger, A; Heinemann, A; Kratky, D Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis.
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Aradska, J; Bulat, T; Sialana, FJ; Birner-Gruenberger, R; Erich, B; Lubec, G Gel-free mass spectrometry analysis of Drosophila melanogaster heads.
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Brandenburg, VM; Kleber, ME; Vervloet, MG; Larsson, TE; Tomaschitz, A; Pilz, S; Stojakovic, T; Delgado, G; Grammer, TB; Marx, N; März, W; Scharnagl, H Soluble klotho and mortality: the Ludwigshafen Risk and Cardiovascular Health Study.
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Roier, S; Blume, T; Klug, L; Wagner, GE; Elhenawy, W; Zangger, K; Prassl, R; Reidl, J; Daum, G; Feldman, MF; Schild, S A basis for vaccine development: Comparative characterization of Haemophilus influenzae outer membrane vesicles.
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Laufs, U; Scharnagl, H; Halle, M; Windler, E; Endres, M; März, W Treatment Options for Statin-Associated Muscle Symptoms.
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Leitner, L; Schuch, K; Jürets, A; Itariu, BK; Keck, M; Grablowitz, V; Aszmann, OC; Prager, G; Staffler, G; Zeyda, M; Stulnig, TM Immunological blockade of adipocyte inflammation caused by increased matrix metalloproteinase-cleaved osteopontin in obesity.
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Almer, G; Mangge, H; Zimmer, A; Prassl, R Lipoprotein-Related and Apolipoprotein-Mediated Delivery Systems for Drug Targeting and Imaging.
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Hartig, SM; Bader, DA; Abadie, KV; Motamed, M; Hamilton, MP; Long, W; York, B; Mueller, M; Wagner, M; Trauner, M; Chan, L; Bajaj, M; Moore, DD; Mancini, MA; McGuire, SE Ubc9 Impairs Activation of the Brown Fat Energy Metabolism Program in Human White Adipocytes.
Mol Endocrinol. 2015; 29(9):1320-1333 Doi: 10.1210/me.2015-1084 [OPEN ACCESS]
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Jain, P; Hassan, AM; Koyani, CN; Mayerhofer, R; Reichmann, F; Farzi, A; Schuligoi, R; Malle, E; Holzer, P Behavioral and molecular processing of visceral pain in the brain of mice: impact of colitis and psychological stress.
Front Behav Neurosci. 2015; 9(5):177-177 Doi: 10.3389/fnbeh.2015.00177 [OPEN ACCESS]
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Dawczynski, C; Kleber, ME; März, W; Jahreis, G; Lorkowski, S Saturated fatty acids are not off the hook.
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Stančić, A; Jandl, K; Hasenöhrl, C; Reichmann, F; Marsche, G; Schuligoi, R; Heinemann, A; Storr, M; Schicho, R The GPR55 antagonist CID16020046 protects against intestinal inflammation.
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Das, SK; Stadelmeyer, E; Schauer, S; Schwarz, A; Strohmaier, H; Claudel, T; Zechner, R; Hoefler, G; Vesely, PW Micro RNA-124a regulates lipolysis via adipose triglyceride lipase and comparative gene identification 58.
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Mangge, H; Prüller, F; Zelzer, S; Ainödhofer, H; Pailer, S; Kieslinger, P; Haybaeck, J; Obermayer-Pietsch, B; Cvirn, G; Gruber, HJ Hypothyroidism Exacerbates Thrombophilia in Female Rats Fed with a High Fat Diet.
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Sala, P; Pötz, S; Brunner, M; Trötzmüller, M; Fauland, A; Triebl, A; Hartler, J; Lankmayr, E; Köfeler, HC Determination of oxidized phosphatidylcholines by hydrophilic interaction liquid chromatography coupled to Fourier transform mass spectrometry.
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Zelzer, S; Mangge, H; Pailer, S; Ainoedhofer, H; Kieslinger, P; Stojakovic, T; Scharnagl, H; Prüller, F; Weghuber, D; Datz, C; Haybaeck, J; Obermayer-Pietsch, B; Trummer, C; Gostner, J; Gruber, HJ Oxidized LDL Is Strictly Limited to Hyperthyroidism Irrespective of Fat Feeding in Female Sprague Dawley Rats.
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Kujala, M; Nevalainen, J; März, W; Laaksonen, R; Datta, S Differential network analysis with multiply imputed lipidomic data.
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Neve, EP; Köfeler, H; Hendriks, DF; Nordling, Å; Gogvadze, V; Mkrtchian, S; Näslund, E; Ingelman-Sundberg, M Expression and Function of mARC: Roles in Lipogenesis and Metabolic Activation of Ximelagatran.
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Rockstroh, D; Landgraf, K; Wagner, IV; Gesing, J; Tauscher, R; Lakowa, N; Kiess, W; Bühligen, U; Wojan, M; Till, H; Blüher, M; Körner, A Direct evidence of brown adipocytes in different fat depots in children.
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Schneider, A; Schneider, MP; Krieter, DH; Genser, B; Scharnagl, H; Stojakovic, T; Wanner, C; Drechsler, C Effect of High-Flux Dialysis on Circulating FGF-23 Levels in End-Stage Renal Disease Patients: Results from a Randomized Trial.
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Schicho, R; Marsche, G; Storr, M Cardiovascular complications in inflammatory bowel disease.
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Jahnel, J; Zöhrer, E; Scharnagl, H; Erwa, W; Fauler, G; Stojakovic, T Reference ranges of serum bile acids in children and adolescents.
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Buechel, HM; Stradner, MH; D'Cruz, LM Stages versus subsets: Invariant Natural Killer T cell lineage differentiation.
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Dražić, T; Sachdev, V; Leopold, C; Patankar, JV; Malnar, M; Hećimović, S; Levak-Frank, S; Habuš, I; Kratky, D Synthesis and evaluation of novel amide amino-β-lactam derivatives as cholesterol absorption inhibitors.
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Ramprecht, C; Jaritz, H; Streith, I; Zenzmaier, E; Köfeler, H; Hofmann-Wellenhof, R; Schaider, H; Hermetter, A Toxicity of oxidized phosphatidylcholines in cultured human melanoma cells.
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Wultsch, A; Kaufmann, U; Ott, J; Stojakovic, T; Scharnagl, H; Stangl, H; Strobl, WM Profound Changes in Sex Hormone Levels during Cross-Sex Hormone Therapy of Transsexuals do not Alter Serum Cholesterol Acceptor Capacity.
J Sex Med. 2015; 12(6):1436-1439 Doi: 10.1111/jsm.12878
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Koyani, CN; Flemmig, J; Malle, E; Arnhold, J Myeloperoxidase scavenges peroxynitrite: A novel anti-inflammatory action of the heme enzyme.
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Falkensammer, J; Frech, A; Duschek, N; Gasteiger, S; Stojakovic, T; Scharnagl, H; Huber, K; Fraedrich, G; Greiner, A Prognostic relevance of ischemia-modified albumin and NT-proBNP in patients with peripheral arterial occlusive disease.
Clin Chim Acta. 2015; 438(1):255-260 Doi: 10.1016/j.cca.2014.08.031
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Adage, T; Konya, V; Weber, C; Strutzmann, E; Fuchs, T; Zankl, C; Gerlza, T; Jeremic, D; Heinemann, A; Kungl, AJ Targeting glycosaminoglycans in the lung by an engineered CXCL8 as a novel therapeutic approach to lung inflammation.
Eur J Pharmacol. 2015; 748(10):83-92 Doi: 10.1016/j.ejphar.2014.12.019
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Meier, SM; Wultsch, A; Hollaus, M; Ammann, M; Pemberger, E; Liebscher, F; Lambers, B; Fruhwürth, S; Stojakovic, T; Scharnagl, H; Schmidt, A; Springer, A; Becker, J; Aufricht, C; Handisurya, A; Kapeller, S; Röhrl, C; Stangl, H; Strobl, W Effect of chronic kidney disease on macrophage cholesterol efflux.
Life Sci. 2015; 136(5):1-6 Doi: 10.1016/j.lfs.2015.06.005
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Jahnel, J; Zöhrer, E; Alisi, A; Ferrari, F; Ceccarelli, S; De Vito, R; Scharnagl, H; Stojakovic, T; Fauler, G; Trauner, M; Nobili, V Serum Bile Acid Levels in Children With Nonalcoholic Fatty Liver Disease.
J Pediatr Gastroenterol Nutr. 2015; 61(1):85-90 Doi: 10.1097/MPG.0000000000000774
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Gerlza, T; Winkler, S; Atlic, A; Zankl, C; Konya, V; Kitic, N; Strutzmann, E; Knebl, K; Adage, T; Heinemann, A; Weis, R; Kungl, AJ Designing a mutant CCL2-HSA chimera with high glycosaminoglycan-binding affinity and selectivity.
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Tomazic, PV; Birner-Gruenberger, R; Leitner, A; Darnhofer, B; Spoerk, S; Lang-Loidolt, D Apolipoproteins have a potential role in nasal mucus of allergic rhinitis patients: a proteomic study.
Laryngoscope. 2015; 125(3):E91-E96 Doi: 10.1002/lary.25003
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Kleber, ME; Siekmeier, R; Delgado, G; Grammer, TB; Winkelmann, BR; Scharnagl, H; Boehm, BO; März, W C-reactive protein and lipoprotein-associated phospholipase A2 in smokers and nonsmokers of the Ludwigshafen Risk and Cardiovascular Health study.
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Schwerdtfeger, AR; Scharnagl, H; Stojakovic, T; Rathner, EM Cognitive Avoidant Coping Is Associated with Higher Carotid Intima Media Thickness Among Middle-Aged Adults.
Int J Behav Med. 2015; 22(5):597-604 Doi: 10.1007/s12529-014-9457-8
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Brückner, A; Stabentheiner, E; Leis, HJ; Raspotnig, G Chemical basis of unwettability in Liacaridae (Acari, Oribatida): specific variations of a cuticular acid/ester-based system.
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Trauner, M; Halilbasic, E; Claudel, T; Steinacher, D; Fuchs, C; Moustafa, T; Pollheimer, M; Krones, E; Kienbacher, C; Traussnigg, S; Kazemi-Shirazi, L; Munda, P; Hofer, H; Fickert, P; Paumgartner, G Potential of nor-Ursodeoxycholic Acid in Cholestatic and Metabolic Disorders.
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Lipovšek, S; Novak, T; Janžekovič, F; Leitinger, G Changes in the midgut diverticula in the harvestmen Amilenus aurantiacus (Phalangiidae, Opiliones) during winter diapause.
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Bokic, T; Storr, M; Schicho, R Potential Causes and Present Pharmacotherapy of Irritable Bowel Syndrome: An Overview.
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Pasterk, L; Philipose, S; Eller, K; Marsche, G; Heinemann, A; Schuligoi, R The EP3 Agonist Sulprostone Enhances Platelet Adhesion But Not Thrombus Formation Under Flow Conditions.
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Mirjanic-Azaric, B; Rizzo, M; Jürgens, G; Hallstroem, S; Srdic, S; Marc, J; Cerne, D Atorvastatin treatment increases plasma bilirubin but not HMOX1 expression in stable angina patients.
Scand J Clin Lab Invest. 2015; 75(5):382-389 Doi: 10.3109/00365513.2015.1031691
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Leis, HJ; Windischhofer, W Molecular characterisation of group IVA (cytosolic) phospholipase A2 in murine osteoblastic MC3T3-E1 cells.
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Silbernagel, G; Baumgartner, I; März, W Cardiovascular Safety of Plant Sterol and Stanol Consumption.
J AOAC Int. 2015; 98(3):739-741 Doi: 10.5740/jaoacint.SGESilbernagel
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Chennamsetty, I; Scharnagl, H; Kleber, ME; Marz, W; Kostner, GM Lipoprotein(a): when to measure and how to treat?
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Izzo, AA; Muccioli, GG; Ruggieri, MR; Schicho, R Endocannabinoids and the Digestive Tract and Bladder in Health and Disease.
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Wruck, W; Kashofer, K; Rehman, S; Daskalaki, A; Berg, D; Gralka, E; Jozefczuk, J; Drews, K; Pandey, V; Regenbrecht, C; Wierling, C; Turano, P; Korf, U; Zatloukal, K; Lehrach, H; Westerhoff, HV; Adjaye, J Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes.
Sci Data. 2015; 2(S 01):150068-150068 Doi: 10.1038/sdata.2015.68 [OPEN ACCESS]
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2014

Lee, JM; Wagner, M; Xiao, R; Kim, KH; Feng, D; Lazar, MA; Moore, DD Nutrient-sensing nuclear receptors coordinate autophagy.
Nature. 2014; 516(7529): 112-115. Doi: 10.1038/nature13961 [OPEN ACCESS]
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Oh, DY; Walenta, E; Akiyama, TE; Lagakos, WS; Lackey, D; Pessentheiner, AR; Sasik, R; Hah, N; Chi, TJ; Cox, JM; Powels, MA; Di Salvo, J; Sinz, C; Watkins, SM; Armando, AM; Chung, H; Evans, RM; Quehenberger, O; McNelis, J; Bogner-Strauss, JG; Olefsky, JM A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.
Nat Med. 2014; 20(8): 942-947. Doi: 10.1038/nm.3614 [OPEN ACCESS]
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Demetz, E; Schroll, A; Auer, K; Heim, C; Patsch, JR; Eller, P; Theurl, M; Theurl, I; Theurl, M; Seifert, M; Lener, D; Stanzl, U; Haschka, D; Asshoff, M; Dichtl, S; Nairz, M; Huber, E; Stadlinger, M; Moschen, AR; Li, X; Pallweber, P; Scharnagl, H; Stojakovic, T; März, W; Kleber, ME; Garlaschelli, K; Uboldi, P; Catapano, AL; Stellaard, F; Rudling, M; Kuba, K; Imai, Y; Arita, M; Schuetz, JD; Pramstaller, PP; Tietge, UJF; Trauner, M; Norata, GD; Claudel, T; Hicks, AA; Weiss, G; Tancevski, I The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism.
Cell Metab. 2014; 20(5):787-798 Doi: 10.1016/j.cmet.2014.09.004 [OPEN ACCESS]
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Walter, KM; Schönenberger, MJ; Trötzmüller, M; Horn, M; Elsässer, HP; Moser, AB; Lucas, MS; Schwarz, T; Gerber, PA; Faust, PL; Moch, H; Köfeler, HC; Krek, W; Kovacs, WJ Hif-2α promotes degradation of Mammalian peroxisomes by selective autophagy.
CELL METAB. 2014; 20(5): 882-897. Doi: 10.1016/j.cmet.2014.09.017 [OPEN ACCESS]
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Ljubojevic, S; Radulovic, S; Leitinger, G; Sedej, S; Sacherer, M; Holzer, M; Winkler, C; Pritz, E; Mittler, T; Schmidt, A; Sereinigg, M; Wakula, P; Zissimopoulos, S; Bisping, E; Post, H; Marsche, G; Bossuyt, J; Bers, DM; Kockskämper, J; Pieske, B Early remodeling of perinuclear Ca2+ stores and nucleoplasmic Ca2+ signaling during the development of hypertrophy and heart failure.
Circulation. 2014; 130(3):244-255 Doi: 10.1161/CIRCULATIONAHA.114.008927 [OPEN ACCESS]
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Scharnagl, H; Kleber, ME; März, W Letter by scharnagl et Al regarding article, "elevated remnant cholesterol causes both low-grade inflammation and ischemic heart disease, whereas elevated low-density lipoprotein cholesterol causes ischemic heart disease without inflammation".
CIRCULATION. 2014; 129(24): e654-e654. Doi: 10.1161/CIRCULATIONAHA.113.006433 [OPEN ACCESS]
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Schicho, R; Storr, M IBD: Patients with IBD find symptom relief in the Cannabis field.
Nat Rev Gastroenterol Hepatol. 2014; 11(3):142-143 Doi: 10.1038/nrgastro.2013.245 [OPEN ACCESS]
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García-Rodríguez, JL; Barbier-Torres, L; Fernández-Álvarez, S; Gutiérrez-de Juan, V; Monte, MJ; Halilbasic, E; Herranz, D; Álvarez, L; Aspichueta, P; Marín, JJ; Trauner, M; Mato, JM; Serrano, M; Beraza, N; Martínez-Chantar, ML SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling.
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Gylling, H; Plat, J; Turley, S; Ginsberg, HN; Ellegard, L; Jessup, W; Jones, PJ; Lutjohann, D; Maerz, W; Masana, L; Silbernagel, G; Staels, B; Boren, J; Catapano, AL; De Backer, G; Deanfield, J; Descamps, OS; Kovanen, PT; Riccardi, G; Tokgozoglu, L; Chapman, MJ Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease
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Mäkelä, KM; Traylor, M; Oksala, N; Kleber, ME; Seppälä, I; Lyytikäinen, LP; Hernesniemi, JA; Kähönen, M; Bevan, S; Rothwell, PM; Sudlow, C; Dichgans, M; Wellcome Trust Case Control Consortium 2 (WTCCC2); Delgado, G; Grammer, TB; Scharnagl, H; Markus, HS; März, W; Lehtimäki, T Association of the novel single-nucleotide polymorphism which increases oxidized low-density lipoprotein levels with cerebrovascular disease events.
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Wree, A; Schlattjan, M; Bechmann, LP; Claudel, T; Sowa, JP; Stojakovic, T; Scharnagl, H; Köfeler, H; Baba, HA; Gerken, G; Feldstein, AE; Trauner, M; Canbay, A Adipocyte cell size, free fatty acids and apolipoproteins are associated with non-alcoholic liver injury progression in severely obese patients.
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Marsche, G; Holzer, M; Wolf, P Antipsoriatic treatment extends beyond the skin: recovering of high-density lipoprotein function.
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Klose, G; Laufs, U; März, W; Windler, E Familial hypercholesterolemia: developments in diagnosis and treatment.
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van Poppel, MN; Zeck, W; Ulrich, D; Schest, EC; Hirschmugl, B; Lang, U; Wadsack, C; Desoye, G Cord blood chemerin: differential effects of gestational diabetes mellitus and maternal obesity.
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Dražić, T; Molčanov, K; Sachdev, V; Malnar, M; Hećimović, S; Patankar, JV; Obrowsky, S; Levak-Frank, S; Habuš, I; Kratky, D Novel amino-β-lactam derivatives as potent cholesterol absorption inhibitors.
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Leis, HJ; Fauler, G; Windischhofer, W Enantioselective quantitative analysis of amphetamine in human plasma by liquid chromatography/high-resolution mass spectrometry.
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Jahnel, J; Fickert, P; Hauer, AC; Högenauer, C; Avian, A; Trauner, M Inflammatory bowel disease alters intestinal bile acid transporter expression.
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Kopf, T; Schaefer, HL; Troetzmueller, M; Koefeler, H; Broenstrup, M; Konovalova, T; Schmitz, G Influence of fenofibrate treatment on triacylglycerides, diacylglycerides and fatty acids in fructose fed rats.
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Kozina, A; Opresnik, S; Wong, MS; Hallström, S; Graier, WF; Malli, R; Schröder, K; Schmidt, K; Frank, S Oleoyl-lysophosphatidylcholine limits endothelial nitric oxide bioavailability by induction of reactive oxygen species.
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Pandey, V; Sultan, M; Kashofer, K; Ralser, M; Amstislavskiy, V; Starmann, J; Osprian, I; Grimm, C; Hache, H; Yaspo, ML; Sültmann, H; Trauner, M; Denk, H; Zatloukal, K; Lehrach, H; Wierling, C Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains.
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Sigruener, A; Kleber, ME; Heimerl, S; Liebisch, G; Schmitz, G; Maerz, W Glycerophospholipid and sphingolipid species and mortality: the Ludwigshafen Risk and Cardiovascular Health (LURIC) study.
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Zatloukal, B; Kufferath, I; Thueringer, A; Landegren, U; Zatloukal, K; Haybaeck, J Sensitivity and specificity of in situ proximity ligation for protein interaction analysis in a model of steatohepatitis with Mallory-Denk bodies.
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Pratter, SM; Ivkovic, J; Birner-Gruenberger, R; Breinbauer, R; Zangger, K; Straganz, GD More than just a halogenase: modification of fatty acyl moieties by a trifunctional metal enzyme.
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Kratky, D; Obrowsky, S; Kolb, D; Radovic, B Pleiotropic regulation of mitochondrial function by adipose triglyceride lipase-mediated lipolysis
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Bettermann, K; Hohensee, T; Haybaeck, J Steatosis and steatohepatitis: complex disorders.
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Kessler, SM; Simon, Y; Gemperlein, K; Gianmoena, K; Cadenas, C; Zimmer, V; Pokorny, J; Barghash, A; Helms, V; van Rooijen, N; Bohle, RM; Lammert, F; Hengstler, JG; Mueller, R; Haybaeck, J; Kiemer, AK Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma.
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Kvaternik, H; Wanek, T; Hammerschmidt, F; Zolle, I; Aigner, R; Kuntner, C Radiosynthesis of [124I]iodometomidate and biological evaluation using small-animal PET.
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Scharnagl, H; Heuschneider, C; Sailer, S; Kleber, ME; März, W; Ritsch, A Decreased cholesterol efflux capacity in patients with low cholesteryl ester transfer protein plasma levels.
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Abumaree, MH; Brownbill, P; Burton, G; Castillo, C; Chamley, L; Croy, BA; Drewlo, S; Dunk, C; Girard, S; Hansson, S; Jones, S; Jurisicova, A; Lewis, R; Letarte, M; Parast, M; Pehrson, C; Rappolee, D; Schneider, H; Tannetta, D; Varmuza, S; Wadsack, C; Wallace, AE; Zenerino, C; Lash, GE IFPA Meeting 2013 Workshop Report III: maternal placental immunological interactions, novel determinants of trophoblast cell fate, dual ex vivo perfusion of the human placenta.
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Hoerl, G; Ledinski, G; Kager, G; Thalhammer, M; Koestenberger, M; Juergens, G; Gary, T; Cvirn, G Virtually same oxidizability of LDL but higher Lp(a) levels in arterial compared to venous plasma.
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Hörl, G; Ledinski, G; Kager, G; Hallström, S; Tafeit, E; Koestenberger, M; Jürgens, G; Cvirn, G In vitro oxidation of LDL by ozone.
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Simon, Y; Kessler, SM; Gemperlein, K; Bohle, RM; Müller, R; Haybaeck, J; Kiemer, AK Elevated free cholesterol in a p62 overexpression model of non-alcoholic steatohepatitis.
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Rossmann, C; Windpassinger, C; Brunner, D; Kovacevic, A; Schweighofer, N; Malli, R; Schuligoi, R; Prokesch, A; Kluve-Beckerman, B; Graier, WF; Kratky, D; Sattler, W; Malle, E Characterization of rat serum amyloid A4 (SAA4): a novel member of the SAA superfamily.
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Trauner, M; Halilbasic, E; Kazemi-Shirazi, L; Kienbacher, C; Staufer, K; Traussnigg, S; Hofer, H Therapeutic role of bile acids and nuclear receptor agonists in fibrosing cholangiopathies.
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Luschnig, P; Frei, R; Lang-Loidolt, D; Rozsasi, A; Tomazic, PV; Lippe, IT; Schuligoi, R; Heinemann, A Altered inhibitory function of the E-type prostanoid receptor 4 in eosinophils and monocytes from aspirin-intolerant patients.
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Schicho, R; Storr, M Cannabis finds its way into treatment of Crohn's disease.
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Graulich, T; Das, SK; Wessels, L; Kummer, W; Hoefler, G; Mühlfeld, C Effects of Lewis lung carcinoma and B16 melanoma on the innervation of the mouse trachea.
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Zinrajh, D; Hörl, G; Jürgens, G; Marc, J; Sok, M; Cerne, D Increased phosphatidylethanolamine N-methyltransferase gene expression in non-small-cell lung cancer tissue predicts shorter patient survival.
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Wanner, C; März, W; Varushchanka, A; Apanasovich, N; Dosta, N; Yakubtsevich, R; Locatelli, F Dyslipidemia in chronic kidney disease: randomized controlled trial of colestilan versus simvastatin in dialysis patients.
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Klose, G; Beil, FU; Dieplinger, H; von Eckardstein, A; Föger, B; Gouni-Berthold, I; Heigl, F; Koenig, W; Kostner, GM; Landmesser, U; Laufs, U; Leistikow, F; März, W; Noll, G; Parhofer, KG; Paulweber, B; Riesen, WF; Schaefer, JR; Steinhagen-Thiessen, E; Steinmetz, A; Toplak, H; Wanner, C; Windler, E; American Heart Association, American College of Cardiology New AHA and ACC guidelines on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk.
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Klose, G; Beil, FU; Dieplinger, H; von Eckardstein, A; Föger, B; Gouni-Berthold, I; Koenig, W; Kostner, GM; Landmesser, U; Laufs, U; Leistikow, F; März, W; Merkel, M; Müller-Wieland, D; Noll, G; Parhofer, KG; Paulweber, B; Riesen, W; Schaefer, JR; Steinhagen-Thiessen, E; Steinmetz, A; Toplak, H; Wanner, C; Windler, E [New AHA and ACC guidelines on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk : Statement of the D•A•CH Society for Prevention of Cardiovascular Diseases, the Austrian Atherosclerosis Society and the Working Group on Lipids and Atherosclerosis (AGLA) of the Swiss Society for Cardiology].
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Karbiener, M; Scheideler, M MicroRNA Functions in Brite/Brown Fat - Novel Perspectives towards Anti-Obesity Strategies.
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Konya, V; Peinhaupt, M; Heinemann, A Adhesion of eosinophils to endothelial cells or substrates under flow conditions.
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Wichro, E; Macheiner, T; Schmid, J; Kavsek, B; Sargsyan, K The Wide and Complex Field of NAFLD Biomarker Research: Trends.
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2013

Do, R; Willer, CJ; Schmidt, EM; Sengupta, S; Gao, C; Peloso, GM; Gustafsson, S; Kanoni, S; Ganna, A; Chen, J; Buchkovich, ML; Mora, S; Beckmann, JS; Bragg-Gresham, JL; Chang, HY; Demirkan, A; Den Hertog, HM; Donnelly, LA; Ehret, GB; Esko, T; Feitosa, MF; Ferreira, T; Fischer, K; Fontanillas, P; Fraser, RM; Freitag, DF; Gurdasani, D; Heikkilä, K; Hyppönen, E; Isaacs, A; Jackson, AU; Johansson, A; Johnson, T; Kaakinen, M; Kettunen, J; Kleber, ME; Li, X; Luan, J; Lyytikäinen, LP; Magnusson, PK; Mangino, M; Mihailov, E; Montasser, ME; Müller-Nurasyid, M; Nolte, IM; O'Connell, JR; Palmer, CD; Perola, M; Petersen, AK; Sanna, S; Saxena, R; Service, SK; Shah, S; Shungin, D; Sidore, C; Song, C; Strawbridge, RJ; Surakka, I; Tanaka, T; Teslovich, TM; Thorleifsson, G; Van den Herik, EG; Voight, BF; Volcik, KA; Waite, LL; Wong, A; Wu, Y; Zhang, W; Absher, D; Asiki, G; Barroso, I; Been, LF; Bolton, JL; Bonnycastle, LL; Brambilla, P; Burnett, MS; Cesana, G; Dimitriou, M; Doney, AS; Döring, A; Elliott, P; Epstein, SE; Eyjolfsson, GI; Gigante, B; Goodarzi, MO; Grallert, H; Gravito, ML; Groves, CJ; Hallmans, G; Hartikainen, AL; Hayward, C; Hernandez, D; Hicks, AA; Holm, H; Hung, YJ; Illig, T; Jones, MR; Kaleebu, P; Kastelein, JJ; Khaw, KT; Kim, E; Klopp, N; Komulainen, P; Kumari, M; Langenberg, C; Lehtimäki, T; Lin, SY; Lindström, J; Loos, RJ; Mach, F; McArdle, WL; Meisinger, C; Mitchell, BD; Müller, G; Nagaraja, R; Narisu, N; Nieminen, TV; Nsubuga, RN; Olafsson, I; Ong, KK; Palotie, A; Papamarkou, T; Pomilla, C; Pouta, A; Rader, DJ; Reilly, MP; Ridker, PM; Rivadeneira, F; Rudan, I; Ruokonen, A; Samani, N; Scharnagl, H; Seeley, J; Silander, K; Stančáková, A; Stirrups, K; Swift, AJ; Tiret, L; Uitterlinden, AG; van Pelt, LJ; Vedantam, S; Wainwright, N; Wijmenga, C; Wild, SH; Willemsen, G; Wilsgaard, T; Wilson, JF; Young, EH; Zhao, JH; Adair, LS; Arveiler, D; Assimes, TL; Bandinelli, S; Bennett, F; Bochud, M; Boehm, BO; Boomsma, DI; Borecki, IB; Bornstein, SR; Bovet, P; Burnier, M; Campbell, H; Chakravarti, A; Chambers, JC; Chen, YD; Collins, FS; Cooper, RS; Danesh, J; Dedoussis, G; de Faire, U; Feranil, AB; Ferrières, J; Ferrucci, L; Freimer, NB; Gieger, C; Groop, LC; Gudnason, V; Gyllensten, U; Hamsten, A; Harris, TB; Hingorani, A; Hirschhorn, JN; Hofman, A; Hovingh, GK; Hsiung, CA; Humphries, SE; Hunt, SC; Hveem, K; Iribarren, C; Järvelin, MR; Jula, A; Kähönen, M; Kaprio, J; Kesäniemi, A; Kivimaki, M; Kooner, JS; Koudstaal, PJ; Krauss, RM; Kuh, D; Kuusisto, J; Kyvik, KO; Laakso, M; Lakka, TA; Lind, L; Lindgren, CM; Martin, NG; März, W; McCarthy, MI; McKenzie, CA; Meneton, P; Metspalu, A; Moilanen, L; Morris, AD; Munroe, PB; Njølstad, I; Pedersen, NL; Power, C; Pramstaller, PP; Price, JF; Psaty, BM; Quertermous, T; Rauramaa, R; Saleheen, D; Salomaa, V; Sanghera, DK; Saramies, J; Schwarz, PE; Sheu, WH; Shuldiner, AR; Siegbahn, A; Spector, TD; Stefansson, K; Strachan, DP; Tayo, BO; Tremoli, E; Tuomilehto, J; Uusitupa, M; van Duijn, CM; Vollenweider, P; Wallentin, L; Wareham, NJ; Whitfield, JB; Wolffenbuttel, BH; Altshuler, D; Ordovas, JM; Boerwinkle, E; Palmer, CN; Thorsteinsdottir, U; Chasman, DI; Rotter, JI; Franks, PW; Ripatti, S; Cupples, LA; Sandhu, MS; Rich, SS; Boehnke, M; Deloukas, P; Mohlke, KL; Ingelsson, E; Abecasis, GR; Daly, MJ; Neale, BM; Kathiresan, S Common variants associated with plasma triglycerides and risk for coronary artery disease.
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Huang, J; Das, SK; Jha, P; Al Zoughbi, W; Schauer, S; Claudel, T; Sexl, V; Vesely, P; Birner-Gruenberger, R; Kratky, D; Trauner, M; Hoefler, G The PPARα agonist fenofibrate suppresses B-cell lymphoma in mice by modulating lipid metabolism.
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Ivashov, VA; Grillitsch, K; Koefeler, H; Leitner, E; Baeumlisberger, D; Karas, M; Daum, G Lipidome and proteome of lipid droplets from the methylotrophic yeast Pichia pastoris.
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Sreckovic, I; Birner-Gruenberger, R; Obrist, B; Stojakovic, T; Scharnagl, H; Holzer, M; Scholler, M; Philipose, S; Marsche, G; Lang, U; Desoye, G; Wadsack, C Distinct composition of human fetal HDL attenuates its anti-oxidative capacity.
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Yu, A; Zheng, Y; Zhang, R; Huang, J; Zhu, Z; Zhou, R; Jin, D; Yang, Z Resistin impairs SIRT1 function and induces senescence-associated phenotype in hepatocytes.
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Nikam, A; Patankar, JV; Lackner, C; Schöck, E; Kratky, D; Zatloukal, K; Abuja, PM Transition between acute and chronic hepatotoxicity in mice is associated with impaired energy metabolism and induction of mitochondrial heme oxygenase-1.
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Oberbach, A; Jehmlich, N; Schlichting, N; Heinrich, M; Lehmann, S; Wirth, H; Till, H; Stolzenburg, JU; Völker, U; Adams, V; Neuhaus, J Molecular fingerprint of high fat diet induced urinary bladder metabolic dysfunction in a rat model.
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Zhang, R; Yan, C; Zhou, X; Qian, B; Li, F; Sun, Y; Shi, C; Li, B; Saito, S; Horimoto, K; Zhou, H Association of Rev-erbα in adipose tissues with Type 2 diabetes mellitus amelioration after gastric bypass surgery in Goto-Kakizaki rats.
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Bernhart, E; Damm, S; Wintersperger, A; DeVaney, T; Zimmer, A; Raynham, T; Ireson, C; Sattler, W Protein kinase D2 regulates migration and invasion of U87MG glioblastoma cells in vitro.
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Eibinger, G; Fauler, G; Bernhart, E; Frank, S; Hammer, A; Wintersperger, A; Eder, H; Heinemann, A; Mischel, PS; Malle, E; Sattler, W On the role of 25-hydroxycholesterol synthesis by glioblastoma cell lines. Implications for chemotactic monocyte recruitment.
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Porpaczy, E; Tauber, S; Bilban, M; Kostner, G; Gruber, M; Eder, S; Heintel, D; Le, T; Fleiss, K; Skrabs, C; Shehata, M; Jager, U; Vanura, K; Lipoprotein lipase in chronic lymphocytic leukaemia - Strong biomarker with lack of functional significance.
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Fauland, A; Trotzmuller, M; Eberl, A; Afiuni-Zadeh, S; Kofeler, H; Guo, XH; Lankmayr, E; An improved SPE method for fractionation and identification of phospholipids.
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Stefulj, J; Peric, M; Malnar, M; Kosicek, M; Schweinzer, C; Zivkovic, J; Scholler, M; Panzenboeck, U; Hecimovic, S Pharmacological activation of LXRs decreases amyloid-β levels in Niemann-Pick type C model cells.
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Waltl-Patankar, S; Patankar, J; Fauler, G; Nusshold, C; Ullen, A; Eibinger, G; Wintersperger, A; Kratky, D; Malle, E; Sattler, W 25-Hydroxycholesterol regulates cholesterol homeostasis in the murine CATH.a neuronal cell line.
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Radulovic, M; Knittelfelder, O; Cristobal-Sarramian, A; Kolb, D; Wolinski, H; Kohlwein, SD The emergence of lipid droplets in yeast: current status and experimental approaches.
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Suvajdzic, L; Leovac, V; Joksovic, M; Bogdanovic, G; Kojic, V; Vujic, N; Mrdja, T; Kocic, B; Antimicrobial Activity of Copper (II) Complex with 1,2-bis [(1,3-diphenylpyrazol-4-yl)methyl] Diaminoethane.
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Schaller, S; Willmann, S; Lippert, J; Schaupp, L; Pieber, TR; Schuppert, A; Eissing, T A Generic Integrated Physiologically based Whole-body Model of the Glucose-Insulin-Glucagon Regulatory System.
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Kumari, M; Schoiswohl, G; Chitraju, C; Paar, M; Cornaciu, I; Rangrez, AY; Wongsiriroj, N; Nagy, HM; Ivanova, PT; Scott, SA; Knittelfelder, O; Rechberger, GN; Birner-Gruenberger, R; Eder, S; Brown, HA; Haemmerle, G; Oberer, M; Lass, A; Kershaw, EE; Zimmermann, R; Zechner, R Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase.
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Grallert, H; Dupuis, J; Bis, JC; Dehghan, A; Barbalic, M; Baumert, J; Lu, C; Smith, NL; Uitterlinden, AG; Roberts, R; Khuseyinova, N; Schnabel, RB; Rice, KM; Rivadeneira, F; Hoogeveen, RC; Fontes, JD; Meisinger, C; Keaney, JF; Lemaitre, R; Aulchenko, YS; Vasan, RS; Ellis, S; Hazen, SL; van Duijn, CM; Nelson, JJ; März, W; Schunkert, H; McPherson, RM; Stirnadel-Farrant, HA; Psaty, BM; Gieger, C; Siscovick, D; Hofman, A; Illig, T; Cushman, M; Yamamoto, JF; Rotter, JI; Larson, MG; Stewart, AF; Boerwinkle, E; Witteman, JC; Tracy, RP; Koenig, W; Benjamin, EJ; Ballantyne, CM Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.
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von Haehling, S; Schefold, JC; Jankowska, EA; Springer, J; Vazir, A; Kalra, PR; Sandek, A; Fauler, G; Stojakovic, T; Trauner, M; Ponikowski, P; Volk, HD; Doehner, W; Coats, AJ; Poole-Wilson, PA; Anker, SD Ursodeoxycholic acid in patients with chronic heart failure: a double-blind, randomized, placebo-controlled, crossover trial.
J Am Coll Cardiol. 2012; 59(6): 585-592. Doi: 10.1016/j.jacc.2011.10.880 [OPEN ACCESS]
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Blättermann, S; Peters, L; Ottersbach, PA; Bock, A; Konya, V; Weaver, CD; Gonzalez, A; Schröder, R; Tyagi, R; Luschnig, P; Gäb, J; Hennen, S; Ulven, T; Pardo, L; Mohr, K; Gütschow, M; Heinemann, A; Kostenis, E A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer.
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Moustafa, T; Fickert, P; Magnes, C; Guelly, C; Thueringer, A; Frank, S; Kratky, D; Sattler, W; Reicher, H; Sinner, F; Gumhold, J; Silbert, D; Fauler, G; Höfler, G; Lass, A; Zechner, R; Trauner, M Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
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Sedej, M; Schröder, R; Bell, K; Platzer, W; Vukoja, A; Kostenis, E; Heinemann, A; Waldhoer, M D-type prostanoid receptor enhances the signaling of chemoattractant receptor-homologous molecule expressed on T(H)2 cells.
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Fuchs, CD; Claudel, T; Kumari, P; Haemmerle, G; Pollheimer, MJ; Stojakovic, T; Scharnagl, H; Halilbasic, E; Gumhold, J; Silbert, D; Koefeler, H; Trauner, M Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice.
Hepatology. 2012; 56(1):270-280 Doi: 10.1002/hep.25601 [OPEN ACCESS]
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Quiroga, AD; Li, L; Trötzmüller, M; Nelson, R; Proctor, SD; Köfeler, H; Lehner, R Deficiency of carboxylesterase 1/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia.
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Patankar, JV; Obrowsky, S; Doddapattar, P; Hoefler, G; Battle, M; Levak-Frank, S; Kratky, D Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis.
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Chen, Y; Jacamo, R; Shi, YX; Wang, RY; Battula, VL; Konoplev, S; Strunk, D; Hofmann, NA; Reinisch, A; Konopleva, M; Andreeff, M Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment.
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Schittmayer, M; Birner-Gruenberger, R Lipolytic proteomics.
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El-Gamal, D; Holzer, M; Gauster, M; Schicho, R; Binder, V; Konya, V; Wadsack, C; Schuligoi, R; Heinemann, A; Marsche, G Cyanate is a novel inducer of endothelial icam-1 expression.
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