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Dorner, TE; Schwarz, F; Kranz, A; Freidl, W; Rieder, A; Gisinger, C.
Body mass index and the risk of infections in institutionalised geriatric patients.
Br J Nutr. 2010; 103(12): 1830-1835. [OPEN ACCESS]
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Autor/innen der Med Uni Graz:
Dorner Thomas
Freidl Wolfgang
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Abstract:
The objective was to examine the effect of BMI on the incidence of various infectious diseases in institutionalised, geriatric subjects. In a retrospective cohort study we analysed medical records of 619 patients aged 75 years and older (mean age 87.6 (sd 6.4) years) who were treated in a geriatric hospital in Vienna, Austria. The total incidence rate of infection in this population was 0.80 per person-year. The most frequent infections were urinary tract infections (0.30 per person-year), followed by infections of the lower respiratory tract (0.19 per person-year), diarrhoea (0.12 per person-year) and other infections (0.20 per person-year). Incidence risk ratios were obtained by a multiplicative Poisson regression model. There was a J-shaped curve in the incidence of infections recorded by BMI with a nadir at 27-28 kg/m2. Compared with the reference group with a BMI of 24-27.9 kg/m2, subjects with a lower BMI had a higher incidence rate of infections. The incidence risk ratios, adjusted for sex, age and chronic diseases, were 1.62 (95 % CI 1.21, 2.17) for those with a BMI of < 20 kg/m2 and 1.84 (95 % CI 1.40, 2.42) for those with a BMI of 20-23.9 kg/m2. However, also patients with a BMI of 28 kg/m2 and above had a higher incidence rate of infections, with an incidence risk ratio of 1.54 (95 % CI 1.07, 2.22). These results show that both underweight and obesity are associated with a higher risk of infections in institutionalised geriatric patients.
Find related publications in this database (using NLM MeSH Indexing)
Aged -
Aged, 80 and over -
Aged, 80 and over - epidemiology
Body Mass Index -
Communicable Diseases - epidemiology
Female -
Hospitalization -
Humans -
Incidence -
Male -
Obesity - complications
Poisson Distribution -
Reference Values -
Respiratory Tract Infections - epidemiology
Retrospective Studies -
Risk Factors -
Thinness - complications
Urinary Tract Infections - epidemiology

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