Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid

Moscarella, E; Rabinovitz, H; Oliviero, MC; Brown, L; Longo, C; Zalaudek, I; Piana, S; Farnetani, F; Lallas, A; Argenziano, G; Pellacani, G.
The role of reflectance confocal microscopy as an aid in the diagnosis of collision tumors.
Dermatology. 2013; 227(2):109-117
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Autor/innen der Med Uni Graz:
Zalaudek Iris
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Abstract:
The term 'collision tumor' refers to the association of 2 or more different neoplasms within the same lesion. The association of a benign neoplasm with a malignant neoplasm is of particular significance and warrants diagnostic accuracy. The purpose of our study was to see if reflectance confocal microscopy (RCM) was a valuable tool when dealing with collision tumors. We retrospectively evaluated 24 histologically confirmed cases of collision tumors, which were initially assessed using dermoscopy and RCM. The malignancy most commonly detected in association with collision tumors was basal cell carcinoma (BCC) (n = 13), followed by melanoma (n = 5, of which 2 collided with BCC) and squamous cell carcinoma in situ (n = 4). Seborrheic keratoses were the most common benign neoplasms found in association with collision tumors (n = 18), followed by nevi (n = 7). Dermoscopy revealed the malignant component in 14 out of 20 lesions compared to RCM, which revealed a malignant component in 19 out of 20 neoplasms. There was excellent concordance between RCM and histopathology with regard to the identification of a malignant component within a tumor (kappa value >0.9). The dermatoscope and the reflectance confocal microscope, when used in conjunction, are valuable tools aiding in the diagnosis of collision tumors.
Find related publications in this database (using NLM MeSH Indexing)
Aged -
Aged, 80 and over -
Dermoscopy - methods
Diagnosis, Differential -
Female -
Follow-Up Studies -
Humans -
Male -
Microscopy, Confocal - methods
Middle Aged -
Neoplasms, Second Primary - diagnosis
Reproducibility of Results -
Retrospective Studies -
Skin Neoplasms - pathology

Find related publications in this database (Keywords)
Dermoscopy
Reflectance confocal microscopy
Collision tumors
Basal cell carcinoma
Melanoma
Squannous cell carcinoma
Seborrheic keratoses
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