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Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid

Seles, M; Hutterer, GC; Kiesslich, T; Pummer, K; Berindan-Neagoe, I; Perakis, S; Schwarzenbacher, D; Stotz, M; Gerger, A; Pichler, M.
Current Insights into Long Non-Coding RNAs in Renal Cell Carcinoma.
Int J Mol Sci. 2016; 17(4):573-573 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Autor/innen der Med Uni Graz:
Gerger Armin
Hutterer Georg C.
Perakis Samantha
Pichler Martin
Pummer Karl
Schwarzenbacher Daniela
Seles Maximilian
Stotz Michael
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Number of Figures: 1
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Abstract:
Renal cell carcinoma (RCC) represents a deadly disease with rising mortality despite intensive therapeutic efforts. It comprises several subtypes in terms of distinct histopathological features and different clinical presentations. Long non-coding RNAs (lncRNAs) are non-protein-coding transcripts in the genome which vary in expression levels and length and perform diverse functions. They are involved in the inititation, evolution and progression of primary cancer, as well as in the development and spread of metastases. Recently, several lncRNAs were described in RCC. This review emphasises the rising importance of lncRNAs in RCC. Moreover, it provides an outlook on their therapeutic potential in the future.

Find related publications in this database (Keywords)
renal cell cancer-carcinoma
long non-coding RNAs
metastases
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