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Cornely, OA; Bassetti, M; Garcia-Vidal, C; Hoenigl, M; Maertens, J; Martin-Loeches, I; Mira, JP; White, PL.
The Importance of Early Mycological Clearance of Uncomplicated Candidaemia and Its Implications for Clinical Practice.
Mycoses. 2025; 68(12): e70135
Doi: 10.1111/myc.70135
[OPEN ACCESS]
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
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Hönigl Martin
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- Abstract:
- Invasive candidiasis is a life-threatening infection associated with high morbidity, mortality and healthcare costs in both general and critical care settings. Timely diagnosis and adequate antifungal treatment are essential to improving patient outcomes and limiting unnecessary use of healthcare resources. This review explores the relationship between early Candida clearance with antifungal therapy, clinical outcomes, resistance patterns and economic impact. It also evaluates the role of diagnostic markers in facilitating early and accurate identification of candidaemia, enabling more precise and effective clinical management. Special attention is given to the challenges of managing candidaemia in critically ill and neutropenic patients, highlighting the need for tailored and timely interventions in these vulnerable populations.
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Humans - administration & dosage
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Antifungal Agents - therapeutic use
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Candidemia - drug therapy, diagnosis, microbiology
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Candida - drug effects, isolation & purification
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Drug Resistance, Fungal - administration & dosage
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Critical Illness - administration & dosage
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Treatment Outcome - administration & dosage
- Find related publications in this database (Keywords)
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antifungal agents
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candidaemia
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PCR
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systemic infection