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Finner, A; Stross, T; Ilić, J; Stix, K; Behrend, ML; Payer, H; Georgi, J; Schmiedhofer, F; Tmava-Berisha, A; Stijic, M; Fleischmann, E; Hammer, S; Hasic, D; Wels, L; Lang, J; Obermayer-Ramirez, A; Maget, A; Platzer, M; Bengesser, S; Häussl, A; Birner, A; Queissner, R; Schönthaler, E; Smolle, S; Mittmannsgruber, C; Lässer, A; Lenger, M; Dalkner, N; Fellendorf, FT; Reininghaus, EZ.
Discrepancies between self- and clinician-rated depressive symptoms in psychiatric inpatients: Associations with treatment stage, age, sex and depression severity.
J Affect Disord. 2025; 121052 Doi: 10.1016/j.jad.2025.121052
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Führende Autor*innen der Med Uni Graz
Finner Alexander
Lenger Melanie
Co-Autor*innen der Med Uni Graz
Behrend Melissa Lajana
Bengesser Susanne
Birner Armin
Dalkner Nina
Fellendorf Frederike
Fleischmann Eva
Georgi Johanna
Hammer Sascha
Hasic Dino
Häussl Alfred Alois
Ilic Julia
Lang Jorgos Nikolas
Lässer Amrei
Maget Alexander
Mittmannsgruber Claudia
Payer Helena Paula
Platzer Martina
Queissner Robert
Ramirez-Obermayer Anna Maria Antonia
Reininghaus Eva
Schmiedhofer Franziska
Schönthaler Elena
Smolle Stefan
Stijic Marko
Stix Katharina
Stross Tatjana Maria
Tmava-Berisha Adelina
Wels Linda
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Abstract:
BACKGROUND: The self-rated Beck Depression Inventory-II (BDI-II) and the clinician-rated Montgomery-Åsberg Depression Rating Scale (MADRS) are widely used to evaluate depressive symptoms in individuals with mental disorders. This study investigated the relationship between BDI-II and MADRS, examining the moderating roles of treatment stage, age, sex, and depression severity in an inpatient cohort diagnosed with major depression. METHODS: A total of 178 adult psychiatric inpatients with moderate to severe depression were assessed at admission and discharge using BDI-II and MADRS. Pearson correlations evaluated the relationship between the scales, Fisher's Z-tests examined changes over time, and moderation analyses and analyses of covariance assessed the role of treatment stage, age, sex, and depression severity. RESULTS: Correlations between BDI-II and MADRS were moderate at admission (r = 0.44, p < .001) and large at discharge (r = 0.56, p < .001), with significant strengthening over time (Fisher's Z = 2.12, p = .034). Correlations improved especially among women and younger patients (Fisher's Z = 3.07-3.08, p = .002), however, age, sex and depression severity did not moderate the association between BDI-II and MADRS (p > .05). Significant symptom reductions were observed for both scales (η2 = 0.63-0.79, p < .001), with age moderating BDI-II improvements (η2 = 0.04, p = .010). DISCUSSION: Our findings reveal that concordance between self-reported and clinician-rated depressive symptoms improves throughout treatment, particularly in subgroups defined by age and sex. The overall association appears consistent. Clinicians should employ both rating perspectives to ensure an individualized understanding of treatment response.

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