Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Logo MUG-Forschungsportal

Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid Stoffw Microb

Fan, KS; Shojaee-Moradie, F; Jeivad, F; Manoli, A; Haidar, A; Borg, Inguanez, M; Sammut, F; Koehler, G; Edwards, V; Lee, V; Falinska, A; Bawlchhim, Z; Mader, JK; Umpleby, AM; Russell-Jones, D, , European, Union, Aviation, Safety, Agency, (EASA), Diabetes, Consortium .
A Dual Stable Isotope Study of the Effect of Altitude and Simulated Flight on Glucose Metabolism in Type 1 Diabetes: A Randomized Crossover Study.
Diabetes. 2025; Doi: 10.2337/db25-0004
PubMed FullText FullText_MUG

 

Co-Autor*innen der Med Uni Graz
Köhler Gerd
Mader Julia
Manoli Antonios
Altmetrics:

Dimensions Citations:

Plum Analytics:

Scite (citation analytics):

Abstract:
The effects of acute atmospheric pressure changes on glucose metabolism in type 1 diabetes remain controversial and may have safety implications for pilots and travelers alike. What are the differences in glucose kinetics and hormones between ground and simulated flight environments? Glucose disposal and insulin concentration are increased in response to a meal during flight, without associated changes in endogenous glucose production or meal glucose appearance rates. Pressure-related changes in insulin pump performance and hypoxia may explain these findings. Because glucose concentrations were unaffected, there is no evidence that insulin pump therapy is a risk factor in flight.

© Med Uni Graz • Impressum