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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Gui, ZH; Heinrich, J; Min, Qian, Z; Schootman, M; Zhao, TY; Xu, SL; Jin, NX; Huang, HH; He, WT; Wu, QZ; Zhang, JL; Wang, DS; Yang, M; Liu, RQ; Zeng, XW; Dong, GH; Lin, LZ.
Exposures to particulate matters and childhood sleep disorders-A large study in three provinces in China.
Environ Int. 2024; 190:108841 Doi: 10.1016/j.envint.2024.108841
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Abstract:
OBJECTIVES: Evidence on the link between long-term ambient particulate matter (PM) exposures and childhood sleep disorders were scarce. We examined the associations between long-term exposures to PM2.5 and PM1 (PM with an aerodynamic equivalent diameter <2.5 μm and <1 μm, respectively) with sleep disorders in children. METHODS: We performed a population-based cross-sectional survey in 177,263 children aged 6 to 18 years in 14 Chinese cities during 2012-2018. A satellite-based spatiotemporal model was employed to estimate four-year annual average PM2.5 and PM1 exposures at residential and school addresses. Parents or guardians completed a checklist using the Sleep Disturbance Scale for Children. We estimated the associations using generalized linear mixed models with adjustment for characteristics of children, parents, and indoor environments. RESULTS: Long-term PM2.5 and PM1 exposures were positively associated with odds of sleep disorders for almost all domains. For example, increments in PM2.5 and PM1 per 10 μg/m3 were associated with odds ratios of global sleep disorder of 1.24 (95 % confidence interval [CI]: 1.14, 1.35) and 1.31 (95 %CI: 1.18, 1.46), respectively. Similar results were observed for subtypes of sleep disorder. These associations were heterogeneous regionally, with stronger associations among children residing in southeast region than in northeast and northwest regions. Moreover, larger estimates of PM1 were found than that of PM2.5 in southeast region. CONCLUSION: Long-term PM2.5 and PM1 exposures are independently associated with higher risks of childhood sleep disorders, and these associations vary by geographical region.
Find related publications in this database (using NLM MeSH Indexing)
Humans - administration & dosage
Particulate Matter - analysis
China - epidemiology
Child - administration & dosage
Adolescent - administration & dosage
Sleep Wake Disorders - epidemiology
Male - administration & dosage
Environmental Exposure - statistics & numerical data
Female - administration & dosage
Cross-Sectional Studies - administration & dosage
Air Pollutants - analysis
Air Pollution - statistics & numerical data

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