Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Sinicina, I; Matevossian, E; Fischer, F; Mall, G; Graw, M.
The petrified heart in sepsis.
Virchows Arch. 2005; 447(5):875-878
Doi: 10.1007/s00428-005-0022-3
(- Case Report)
Web of Science
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- Co-Autor*innen der Med Uni Graz
- Fischer Florian Tobias
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- Abstract:
- We report the case of a 33-year-old transsexual man who developed severe sepsis after an accidental intravenous injection of urine (3-5 ml) instead of methadone. He died unexpectedly 28 days after the onset of sepsis. On postmortem examination, the outstanding findings were restricted to the heart with an unusual macroscopic presentation. On histological examination extensive calcifications of the heart muscle, particularly of the left ventricle were found. The pattern of calcifications on the right ventricle was also striking. In contrast, the entire cardial conduction system was unaffected. Furthermore, there were no calcium deposits in other organs and tissues. The advanced widespread cardial calcifications in the present case can be attributed to endotoxin-related myocarditis in severe long-term sepsis. The only treatment would have been an urgent heart transplantation. Without prior knowledge of such a condition, it is impossible for clinicians to correctly recognize, diagnose and treat or prevent in due time such a complication.
- Find related publications in this database (using NLM MeSH Indexing)
- Accidents -
- Adult -
- Calcinosis - etiology Calcinosis - pathology
- Cardiomyopathies - etiology Cardiomyopathies - pathology
- Endotoxins - adverse effects
- Fatal Outcome -
- Heart Ventricles - pathology
- Humans -
- Injections, Intravenous - adverse effects
- Male -
- Myocardium - pathology
- Sepsis - etiology Sepsis - pathology
- Transsexualism -
- Urine -
- Find related publications in this database (Keywords)
- intravenous injection of urine
- sepsis
- myocardial calcification