Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Schlemmer, AJ; Gorkiewicz, G; Uggowitzer, MM; Salamon, S; Jost, P; Talakic, E.
18F-FDG PET/CT in NUT Carcinoma of the Thorax.
Clin Nucl Med. 2025;
Doi: 10.1097/RLU.0000000000005872
PubMed
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- Führende Autor*innen der Med Uni Graz
- Schlemmer Anselm Johannes
- Talakic Emina
- Co-Autor*innen der Med Uni Graz
- Gorkiewicz Gregor
- Jost Philipp
- Salamon Spela
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- Abstract:
- NUT carcinoma (NUTc) is a rare, aggressive cancer characterized by rearrangement of the NUTM1 gene on chromosome 15q14. We present the case of a 32-year-old man with a persisting cough, reduced general condition, and B symptoms for 2 months. CT imaging revealed a highly suspicious mass in the right lung, infiltrating hilar structures, and the mediastinum. Staging with 18F-FDG PET/CT demonstrated pathologic 18F-FDG uptake within the tumor. Histology, immunohistochemistry, and molecular analysis confirmed NUTc of the lung. Metabolic imaging modalities may play a key role in staging, restaging, and assessing treatment response in patients with NUTc.