Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Fruhauf, J; Schaider, H; Massone, C; Kerl, H; Mullegger, RR.
Carbamazepine as the only effective treatment in a 52-year-old man with trigeminal trophic syndrome.
MAYO CLIN PROC. 2008; 83(4): 502-504.
Doi: 10.4065/83.4.502
(- Case Report)
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- Führende Autor*innen der Med Uni Graz
- Frühauf Julia
- Co-Autor*innen der Med Uni Graz
- Kerl Helmut
- Massone Cesare
- Muellegger Robert
- Schaider Helmut
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- Abstract:
- Trigeminal trophic syndrome is a rare condition resulting from self-manipulation of the skin after a peripheral or central injury to the trigeminal system. The syndrome consists of a classic triad of anesthesia, paresthesias, and secondary persistent or recurrent facial ulcerations. The most common causes include destruction of the trigeminal ganglion, rhizotomy, and stroke. We describe a patient who developed the syndrome as a sequel to brainstem infarction and trigeminal neuropathy. Whereas a-lipoic acid and gabapentin were ineffective, a remarkable benefit was achieved by administering carbamazepine (200 mg 3 times a day), which influences both neuropathic and behavioral factors in this rare syndrome. Our experience with the presented case, together with the scarce information in the literature, indicates that carbamazepine should be the first treatment option for trigeminal trophic syndrome.
- Find related publications in this database (using NLM MeSH Indexing)
- Antimanic Agents - therapeutic use
- Brain Stem Infarctions - complications
- Carbamazepine - therapeutic use
- Follow-Up Studies -
- Humans -
- Male -
- Middle Aged -
- Syndrome -
- Trigeminal Nerve Diseases - drug therapy Trigeminal Nerve Diseases - etiology