Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Valent, P; Krieger, O; Stauder, R; Wimazal, F; Nösslinger, T; Sperr, WR; Sill, H; Bettelheim, P; Pfeilstöcker, M.
Iron overload in myelodysplastic syndromes (MDS) - diagnosis, management, and response criteria: a proposal of the Austrian MDS platform.
Eur J Clin Invest. 2008; 38(3):143-149
Doi: 10.1111/j.1365-2362.2007.01915.x
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Sill Heinz
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Transfusion-related morbidity is an emerging challenge in chronically transfused patients with low-risk myelodysplastic syndromes (MDS). In these patients, transfusion-induced iron overload may represent a leading medical problem. However, although iron-chelating drugs are available, little is known about optimal diagnostic tools, predisposing factors, and the optimal management of these patients. In the current article, we provide recommendations for the diagnosis, prevention and treatment of iron overload in MDS and propose treatment response criteria. Consensus criteria and resulting recommendations were discussed and formulated by members of the MDS platform of the Austrian Society of Haematology and Oncology in a series of meetings and conferences in 2006 and 2007. These recommendations should facilitate and assist in recognition of iron overload, selection of patients, timing of treatment, drug selection and the measurement of treatment responses.
- Find related publications in this database (using NLM MeSH Indexing)
- Chelation Therapy - methods
- Erythrocyte Transfusion - adverse effects
- Ferritins - blood
- Guidelines as Topic -
- Humans -
- Iron Chelating Agents - therapeutic use
- Iron Overload - physiopathology
- Myelodysplastic Syndromes - complications
- Find related publications in this database (Keywords)
- chelation
- ferritin
- HFE
- iron overload
- response criteria
- transfusions