Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Zaupa, P; Kleinlein, B; Höllwarth, ME.
Bilateral congenital diaphragmatic hernia and gastroschisis in a newborn: can low intrathoracic pressure prevent the pulmonary hypoplasia?
Pediatr Surg Int. 2007; 23(7):711-713
Doi: 10.1007/s00383-006-1873-7
(- Case Report)
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- Führende Autor*innen der Med Uni Graz
- Zaupa Paola
- Co-Autor*innen der Med Uni Graz
- Höllwarth Michael
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- Abstract:
- Congenital diaphragmatic hernia (CDH) is associated with high mortality and morbidity due to pulmonary hypoplasia (PH) and persistent pulmonary hypertension (PPH). Bilateral CDH is extremely rare with poor prognosis. It is usually accepted that PH in CDH is due to the herniation of abdominal viscera in the thorax leading to compression of the lung and preventing the normal lung development. On the other hand, some authors suggest that the PH occurs independently from the intrathoracic pressure in foetuses with CDH because of embryologic and genetic factors. We report a case of a newborn with bilateral CDH and gastroschisis born without PH, with favourable outcome. We support the hypothesis that a low intrathoracic pressure in patients with CDH allows an improved lung development.
- Find related publications in this database (using NLM MeSH Indexing)
- Diagnosis, Differential -
- Gastroschisis - complications
- Hernia, Diaphragmatic - congenital
- Humans - congenital
- Infant, Newborn - congenital
- Lung - abnormalities
- Magnetic Resonance Imaging - abnormalities
- Male - abnormalities
- Pressure - abnormalities
- Radiography, Thoracic - abnormalities
- Thorax - abnormalities