Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Mulabecirovic, A; Gaulhofer, P; Auner, HW; Popper, H; Krause, R; Hesse, C; Sill, H.
Pulmonary infiltrates in patients with haematologic malignancies: transbronchial lung biopsy increases the diagnostic yield with respect to neoplastic infiltrates and toxic pneumonitis.
ANN HEMATOL. 2004; 83(7): 420-422.
Doi: 10.1007/s00277-004-0876-5
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- Führende Autor*innen der Med Uni Graz
- Sill Heinz
- Co-Autor*innen der Med Uni Graz
- Hesse Christian
- Krause Robert
- Popper Helmuth
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- Abstract:
- We retrospectively evaluated 107 fiberoptic bronchoscopies with and without transbronchial lung biopsy (TBLB) in 98 consecutive patients with haematologic malignancies and pulmonary infiltrates. Bronchoalveolar lavage (BAL) was performed in 45 and BAL plus TBLB in 62 procedures. There was no procedure-related severe haemorrhage, pneumothorax or death. Infectious aetiology was identified in 26 of 107 (24%), toxic pneumonitis in 17 of 107 (16%) and neoplastic infiltration in 9 of 107 (8.5%) episodes. Combined BAL and TBLB was significantly superior to BAL alone with respect to the diagnosis of neoplastic infiltrates (p=0.008) and toxic pneumonitis (p<0.001) and should therefore be included in the diagnostic work-up of this patient cohort.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Antineoplastic Agents - adverse effects
- Biopsy - adverse effects
- Bronchoalveolar Lavage Fluid - adverse effects
- Bronchoscopy - adverse effects
- Cohort Studies - adverse effects
- Disease Progression - adverse effects
- Female - adverse effects
- Fiber Optics - adverse effects
- Hematologic Neoplasms - complications
- Hemorrhage - etiology
- Humans - etiology
- Leukemic Infiltration - etiology
- Lung - pathology
- Lung Diseases - diagnosis
- Male - diagnosis
- Middle Aged - diagnosis
- Myelodysplastic Syndromes - complications
- Platelet Transfusion - complications
- Pneumonia - chemically induced
- Predictive Value of Tests - chemically induced
- Retrospective Studies - chemically induced
- Find related publications in this database (Keywords)
- pulmonary infiltrates
- haematologic malignancies
- fiberoptic bronchoscopy
- bronchoalveolar lavage
- transbronchial lung biopsy