Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Eberl, AS; Plank, G; Manninger, M; Rohrer, U; Stix, L; Kurath-Koller, S; Zirlik, A; Scherr, D.
Biophysics and Clinical Effectiveness of Irreversible Electroporation for Catheter Ablation of Atrial Fibrillation.
J Cardiovasc Dev Dis. 2025; 12(6):
Doi: 10.3390/jcdd12060218
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- Führende Autor*innen der Med Uni Graz
- Eberl Anna-Sophie
- Co-Autor*innen der Med Uni Graz
- Kurath-Koller Stefan
- Manninger-Wünscher Martin
- Plank Gernot
- Rohrer Ursula
- Scherr Daniel
- Zirlik Andreas
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- Abstract:
- Understanding the biophysics of electroporation-the mechanism by which pulsed electric fields achieve tissue ablation-is essential for advancing this emerging technology. In this review, we summarize key publications from past years to provide an overview of current knowledge and future perspectives. We discuss the fundamental principles of PFA at the cellular, physical, and technical levels, along with its potential benefits and limitations. A deeper understanding of these biophysical mechanisms and the parameters required to create durable lesions may contribute to improved clinical outcomes and drive future innovation.
- Find related publications in this database (Keywords)
- ablation
- atrial fibrillation
- biophysics
- pulsed electric field
- pulsed field ablation