Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Bracic, M; Nagy, BM; Plohl, O; Lackner, F; Steindorfer, T; Fischer, RC; Heinze, T; Olschewski, A; Kleinschek, KS; Nagaraj, C; Mohan, T.
Antithrombogenic polysaccharide coatings to improve hemocompatibility, protein-repellence, and endothelial cell response
ISCIENCE. 2024; 27(9): 110692
Doi: 10.1016/j.isci.2024.110692
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- Führende Autor*innen der Med Uni Graz
- Chandran Nagaraj
- Co-Autor*innen der Med Uni Graz
- Nagy Miklos Bence
- Olschewski Andrea
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- Abstract:
- Polyester biomaterials play a crucial in vascular surgery, but suffer from unspecific protein adsorption, sues, we investigated the functionalization of polyester biomaterials with antithrombogenic polysaccharide coatings. A two-step and water-based method was used to coat cationized polycaprolactone with icantly increased the anticoagulant activity and reduced the thrombogenicity of polycaprolactone, particcorrelated with the type and sulfate content of the coatings.
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