Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Skok, K; Gradišnik, L; Maver, U; Kozar, N; Sobočan, M; Takač, I; Arko, D; Kavalar, R.
Gynaecological cancers and their cell lines.
J Cell Mol Med. 2021; 25(8): 3680-3698.
Doi: 10.1111/jcmm.16397
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- Führende Autor*innen der Med Uni Graz
- Skok Kristijan
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- Abstract:
- Cell lines are widely used for various research purposes including cancer and drug research. Recently, there have been studies that pointed to discrepancies in the literature and usage of cell lines. That is why we have prepared a comprehensive overview of the most common gynaecological cancer cell lines, their literature, a list of currently available cell lines, and new findings compared with the original studies. A literature review was conducted via MEDLINE, PubMed and ScienceDirect for reviews in the last 5 years to identify research and other studies related to gynaecological cancer cell lines. We present an overview of the current literature with reference to the original studies and pointed to certain inconsistencies in the literature. The adherence to culturing rulesets and the international guidelines helps in minimizing replication failure between institutions. Evidence from the latest research suggests that despite certain drawbacks, variations of cancer cell lines can also be useful in regard to a more diverse genomic landscape.
- Find related publications in this database (using NLM MeSH Indexing)
- Cell Culture Techniques - methods
- Cell Line, Tumor - administration & dosage
- Female - administration & dosage
- Genital Neoplasms, Female - pathology
- Humans - administration & dosage
- Find related publications in this database (Keywords)
- breast neoplasm
- cell line
- cervix cancer
- endometrial neoplasms
- gynaecology
- in vitro techniques
- pathology
- tumour cell line