Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Szappanos, S; Farkas, R; Lőcsei, Z; László, Z; Kalincsák, J; Bellyei, S; Sebestyén, Z; Csapó, L; Sebestyén, K; Halász, J; Musch, Z; Beöthe, T; Farkas, L; Mangel, L.
[New methods in the treatment of localized prostate cancer: use of dynamic arc therapy and kV cone-beam CT positioning].
Orv Hetil. 2014; 155(32): 1265-72.
Doi: 10.1556/OH.2014.29883
PubMed
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- Co-Autor*innen der Med Uni Graz
- Löcsei Zoltan
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- Abstract:
- INTRODUCTION: Prostate cancer is a common disease among elderly male patients in developed countries. In addition to prostatectomy, definitive irradiation plays an increasing role in the treatment of localized disease. AIM: The authors wanted to share their experience obtained with the use of the Novalis TX linear accelerator for the application of dose-escalation, dynamic, intensity modulated arc therapy with the routine usage of cone-beam computer tomography based or image guided radiotherapy in patients with prostate cancer. METHOD: Between 2011, December and 2013, February the authors performed 102 treatments. In 10 low risk and 10 high risk prostate cancer patients (median age: 72.5 years) three-dimensional conformal plans with the same target volume coverage were created and tolerance doses of organs at risk (OAR) were compared. RESULTS: Compared to three-dimensional conformal techniques, intensity modulated arc therapy treatments produced a significantly lower dose at organ at risk that led to a more favorable early toxicity rate. CONCLUSIONS: The intensity modulated arc therapy with image guided radiotherapy proved to be a safe standard treatment mode in the daily routine in the institute of the authors. Late toxicity and local control rates need to be further examined.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged - administration & dosage
- Biomarkers, Tumor - blood
- Cone-Beam Computed Tomography - administration & dosage
- Humans - administration & dosage
- Hungary - epidemiology
- Male - administration & dosage
- Neoplasm Grading - administration & dosage
- Neoplasm Staging - administration & dosage
- Prostate-Specific Antigen - blood
- Prostatic Neoplasms - blood, epidemiology, pathology, radiotherapy
- Radiation Injuries - etiology, prevention & control
- Radiotherapy Dosage - administration & dosage
- Radiotherapy Planning, Computer-Assisted - methods
- Radiotherapy, Conformal - instrumentation, methods
- Radiotherapy, Image-Guided - instrumentation, methods
- Radiotherapy, Intensity-Modulated - methods
- Retrospective Studies - administration & dosage
- Treatment Outcome - administration & dosage