Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Huang, CG; Li, MZ; Wang, SH; Tang, XQ; Zhang, HL; Haybaeck, J; Yang, ZH.
Giant cell tumor of tendon sheath: A report of 216 cases.
J Cutan Pathol. 2023; 50(4):338-342
Doi: 10.1111/cup.14344
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Haybäck Johannes
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- Abstract:
- BACKGROUND: In this article on giant cell tumor of tendon sheath (GCTTS), we intend to summarize and analyze the clinical and pathological features of GCTTS hoping to improve clinical management and patient treatment. METHODS: The study retrospectively reviewed 216 patients of GCTTS, registered at the Affiliated Hospital of Southwest Medical University from January 2010 to December 2020. These cases were diagnosed by surgical excision. The clinicopathological features and the prognosis were reviewed in the light of the current literature. RESULTS: Of these 216 GCTTS patients, 72 were males (33.3%) and 144 females (66.7%), with a ratio male-to-female of 1:2. The patients' age ranged from 5 to 82, the average being 41.5 years at diagnosis. A total of 96 cases (44.4%) occurred in the hand region, followed by 35 cases (16.2%) in the knee, 32 cases (14.8%) in the foot, 25 cases (11.6%) in the ankle, 12 cases (5.6%) in the wrist, 12 cases (5.6%) in the leg, 2 cases (0.9%) in the head, 1 case (0.5%) in the forearm, and 1 case (0.5%) inside and outside the spinal channel. Histopathology mainly revealed large synovial-like monocytes, small monocytes, and osteoclast-like giant cells. CONCLUSION: Our results confirm that GCTTS predominantly occurs in the hands of young women. Complete surgical resection with long-term follow-up is the preferred management.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Male - administration & dosage
- Female - administration & dosage
- Child, Preschool - administration & dosage
- Child - administration & dosage
- Adolescent - administration & dosage
- Young Adult - administration & dosage
- Adult - administration & dosage
- Middle Aged - administration & dosage
- Aged - administration & dosage
- Aged, 80 and over - administration & dosage
- Tendons - surgery, pathology
- Retrospective Studies - administration & dosage
- Giant Cell Tumors - pathology
- Giant Cell Tumor of Tendon Sheath - surgery, diagnosis, pathology
- Giant Cells - pathology
- Find related publications in this database (Keywords)
- clinical analysis
- giant cell tumor
- pathology
- tendon sheath