Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Berek, K; Fava, E; Zinganell, A; Hegen, H; Auer, M; Wurth, S; Rhomberg, P; Deisenhammer, F; Di Pauli, F.
Transverse myelitis as a rare presentation of antiphospholipid-antibody-associated disorders.
Mult Scler Relat Disord. 2020; 45(10):102405-102405
Doi: 10.1016/j.msard.2020.102405
(- Case Report)
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- Co-Autor*innen der Med Uni Graz
- Wurth Sebastian
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- Abstract:
- We report the case of a 35-year-old male patient suffering from a clinical and radiological manifestation of a transverse myelitis associated with antiphospholipid antibodies. After a challenging diagnosis the patient improved substantially due to immunosuppressive treatment. The demyelinating spinal cord lesion and the impressive therapeutic outcome may support the possibility of a direct binding of antiphospholipid antibodies to CNS antigens and consequently leading to a neuroimmunological pathomechanism distinct from the well-known pro-thrombotic effect of antiphospholipid antibodies. In terms of clinical routine diagnostic this case report highlights a rare but notable differential diagnosis of Multiple Sclerosis-like syndromes. Copyright © 2020 Elsevier B.V. All rights reserved.
- Find related publications in this database (Keywords)
- Antiphospholipid antibodies
- aPL
- Antiphospholipid syndrome
- APS, Transverse myelitis
- Spinal lesion