Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Kuntz, M; Kohlfürst, DS; Feiterna-Sperling, C; Krüger, R; Baumann, U; Buchtala, L; Elling, R; Grote, V; Hübner, J; Hufnagel, M; Kaiser-Labusch, P; Liese, J; Otto, EM; Rose, MA; Schneider, C; Schuster, V; Seidl, M; Sommerburg, O; Vogel, M; von Bernuth, H; Weiß, M; Zimmermann, T; Nieters, A; Zenz, W; Henneke, P; NTMkids Consortium.
Risk Factors for Complicated Lymphadenitis Caused by Nontuberculous Mycobacteria in Children.
Emerg Infect Dis. 2020; 26(3):579-586
Doi: 10.3201/eid2603.191388
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- Co-Autor*innen der Med Uni Graz
- Kohlfürst Daniela
- Zenz Werner
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- Abstract:
- Nontuberculous mycobacteria (NTM) are an emerging cause of infections, including chronic lymphadenitis in children. To identify risk factors for NTM lymphadenitis, particularly complicated disease, we collected epidemiologic, clinical, and microbiological data on 138 cases of NTM lymphadenitis in children across 13 centers in Germany and Austria. We assessed lifestyle factors but did not identify specific risk behaviors. We noted that more cases of NTM lymphadenitis occurred during cold months than during warm months. Moreover, we noted female sex and age <5.5 years as potential risk factors. Complete extirpation of the affected lymph node appeared to be the best therapeutic measure. We integrated the study data to develop a simple risk score to predict unfavorable clinical outcomes for NTM lymphadenitis.