Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Schittek, GA; Simonis, H; Fischer, M; Soukup, J.
[Severe Shock Symptoms Due to Ticagrelor Related Anaphylactoid Reaction Following ST Elevation Myocardial Infarction].
Anasthesiol Intensivmed Notfallmed Schmerzther. 2019; 54(10): 630-634.
Doi: 10.1055/a-0901-6613
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- Führende Autor*innen der Med Uni Graz
- Schittek Gregor Alexander
- Co-Autor*innen der Med Uni Graz
- Simonis Holger
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- Abstract:
- Ticagrelor as a P2Y12 receptor antagonist is recommended in patients with acute coronary syndrome without a primary cardiosurgical therapy. Severe relevant side effects, especially anaphylactic reactions, have not yet been described in the current literature. We describe the first documented case in the current literature with a severe anaphylaxis after ticagrelor in a 76-year-old male patient with ST-elevation myocardial infarction. The diagnosis seems to be objectivated by the observed time-related life-threatening event after repetitive administration of ticagrelor and the rapid stabilization after adequate anaphylactic treatment. This case should raise the awareness that a supposedly safe drug can still cause an anaphylactic shock. Georg Thieme Verlag KG Stuttgart · New York.