Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Hruşcã, A; Rãchişan, AL; Rödl, S; Sorantin, E.
Can Apparent Diffusion Coefficient Predict the Clinical Outcome in Drowned Children?
Can Assoc Radiol J. 2017; 68(2):217-223
Doi: 10.1016/j.carj.2016.12.001
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Roedl Siegfried
- Sorantin Erich
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- Abstract:
- Pediatric cerebral hypoxic-ischemic injury frequently results in severe neurological outcome. Imaging with diffusion-weighted magnetic resonance imaging (DWi) demonstrates that the acute cerebral injury and apparent diffusion coefficient (ADC) allow the assessment of the severity of brain damage. The main objective was to examine if spatial distribution of reductions in ADC values is associated with clinical outcome in drowned children. This is a retrospective study of 7 children (7 examinations) suffering from a hypoxic-ischemic event who underwent DWi. Seven subjects with normal DWi served as controls. The mean patient age was 4.88 ± 2.93 years and the male-to-female ratio was 5:2. The neurological outcome was divided into 2 categories: 4 children with Apallic syndrome and 3 deaths. We analysed the differences between the drowned children and the control group regarding clinical data, DWi abnormalities, and ADC values. The ADC values in the occipital and parietal grey matter were significantly different between the drowned children (765.14 ± 65.47 vs 920.95 ± 69.62; P = .003) and the control group (670.82 ± 233.99 vs 900.66 ± 92.72; P = .005). The ADC showed low values in the precentral area also (P = .044). The ADC reduction may be useful to predict the poor outcome in drowned children and can be a valuable tool for clinical assessment. Copyright © 2016 Canadian Association of Radiologists. Published by Elsevier Inc. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Child, Preschool -
- Diffusion Magnetic Resonance Imaging -
- Female -
- Humans -
- Hypoxia-Ischemia, Brain - diagnostic imaging
- Hypoxia-Ischemia, Brain - etiology
- Male -
- Near Drowning - complications
- Near Drowning - diagnostic imaging
- Predictive Value of Tests -
- Prognosis -
- Retrospective Studies -
- Find related publications in this database (Keywords)
- Apparent diffusion coefficient
- Diffusion-weighted imaging
- Drowning
- Cerebral