Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Pahlavan, PS; Mehrabi, A; Kashfi, A; Soleimani, M; Fani-Yazdi, SH; Schemmer, P; Gutt, CN; Friess, H; Weitz, J; Kraus, TW; Büchler, MW; Schmidt, J.
Guidelines for prevention and management of complications following kidney transplantation in rats.
Transplant Proc. 2005; 37(5):2333-2337
Doi: 10.1016/j.transproceed.2005.03.056
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Schemmer Peter
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- Abstract:
- Kidney transplantation in rats is a useful model for microsurgery, transplantation, and immunology studies. Our aim was to analyze various techniques of kidney transplantation in rats with emphasis on guidelines for the prevention and management of complications. Complications were categorized into general, vascular, and urological types and respectively attributed to long transplantation time, core body temperature drop, nonreplaced intraoperative blood loss, anastomosis failure, and ureteral anastomoses with stents or cannulas, which increase the risk of calculus formation. In conclusion, to decrease the complication rates the animal should be placed on a heating pad. For hemodynamic stability NaCl should be administered subcutaneously. To reduce the risk of thrombosis, ice-cold saline containing heparin should be administered. Vascular complications, which mainly depend on the microsurgeon's expertise, can be prevented by meticulous surgical technique (preferably an end-in-end anastomosis). The main urinary complications can be minimized by avoiding stents and cannulas and focusing on using techniques like the bladder-patch technique.
- Find related publications in this database (using NLM MeSH Indexing)
- Animal Husbandry - standards
- Animals -
- Guidelines as Topic -
- Kidney Transplantation - methods
- Kidney Transplantation - pathology
- Kidney Transplantation - standards
- Models, Animal -
- Postoperative Complications - prevention & control
- Rats -
- Transplantation, Heterotopic -
- Urologic Diseases - etiology
- Urologic Diseases - prevention & control