Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Zittermann A; Pilz, S.
Vitamin D in Klinik und Praxis
AKTUELLE ERNÄHRUNGSMEDIZIN. 2016; 41: 300-316.
Doi: 10.1055/s-0042-110724
Web of Science
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- Co-Autor*innen der Med Uni Graz
- Pilz Stefan
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- Abstract:
- Vitamin D is unique among the vitamins, since its major source is skin synthesis by solar UVB exposure, whereas dietary intake plays only a minor role. Major risk factors of vitamin D deficiency are Germany's geography, climate and several individual parameters that limit skin synthesis of vitamin D. In the general population, cutaneous vitamin D synthesis is in summer and winter 12.5-15 mu g/day and 0 mu g/day, respectively, and thus clearly below the recommended amount of 20 mu g/day. Dietary vitamin D intakes (on average 2.2-2.9 mu g/day) do not fill this gap. About 15-18% of the general population and 25% of patients have deficient blood levels of 25-hydroxyvitamin D (<30nmol/l). The proportion is even higher in nursing home residents and non-European migrants. Severe vitamin D deficiency results in rickets in infants and osteomalacia in adults. Moreover, there is convincing evidence that in elderly people vitamin D reduces fracture risk by up to 20%. Likely evidence exists that vitamin D reduces mortality risk by 10% and contributes to reduced risk of airway infections in all age groups. In the absence of endogenous vitamin D synthesis (e.g. during winter), oral supplements should ensure adequate daily vitamin D intake, where appropriate. This is particularly true for nursing home residents, non-European migrants and dark-skinned people.
- Find related publications in this database (Keywords)
- vitamin D
- deficit
- toxicity
- supplements
- fractures
- mortality