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Fritsch, M; Schober, E; Rami-Merhar, B; Hofer, S; Fröhlich-Reiterer, E; Waldhoer, T; Austrian Diabetes Incidence Study Group.
Diabetic ketoacidosis at diagnosis in Austrian children: a population-based analysis, 1989-2011.
J Pediatr. 2013; 163(5):1484-1488
Doi: 10.1016/j.jpeds.2013.06.033
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
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Fritsch Maria
- Co-Autor*innen der Med Uni Graz
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Fröhlich-Reiterer Elke
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- Abstract:
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To analyze the effect of a community-based, poster-focused prevention program on the frequency of diabetic ketoacidosis (DKA) at diabetes onset in Austria.
All newly diagnosed patients with diabetes ≤ 15 years of age were registered prospectively by the Austrian Diabetes Incidence Study Group. Registered data included initial blood glucose, pH, and ketonuria. DKA was defined as pH < 7.3 and severe DKA as pH < 7.1. Data between 1989 and 2011 were available. In autumn, 2009, a community-based prevention program similar to the Parma Campaign, in which posters were dispensed broadly, was initiated. The frequency of DKA at the onset of diabetes in the years 2005-2009 and 2010-2011 was compared.
During the study period, 4038 children were registered. A total of 37.2% presented with DKA; 26% had a mild and 11.2% a severe form. The frequency of DKA was negatively associated with age at onset. In the years before the intervention program, 26% had mild DKA compared with 27% after the intervention (not significant). The prevalence of severe DKA in the years before the campaign was 12% compared with 9.5% thereafter (not significant). No significant change in the DKA rate at onset by the prevention program could be found when we compared age groups <5, 5 to <10, and 10 to <15 years, neither for mild nor for severe DKA.
The frequency of DKA in children with newly diagnosed type 1 diabetes in Austria is high and did not change despite the efforts of a community-based information program.
Copyright © 2013. Published by Mosby, Inc.
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Adolescent -
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Age of Onset -
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Age of Onset - epidemiology
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Blood Glucose - analysis
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Child -
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Child, Preschool -
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Community Health Services -
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Diabetes Mellitus, Type 1 - blood
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Diabetes Mellitus, Type 1 - diagnosis
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Diabetic Ketoacidosis - diagnosis
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Diabetic Ketoacidosis - epidemiology
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Diabetic Ketoacidosis - prevention & control
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Female -
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Health Communication -
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Humans -
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Hydrogen-Ion Concentration -
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Incidence -
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Ketosis - diagnosis
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Male -
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Outcome Assessment (Health Care) -
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Preventive Medicine - methods
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Prospective Studies -
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Public Health -
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Registries -