Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Schweiger, M; Schrempf, J; Sereinigg, M; Prenner, G; Tscheliessnigg, KH; Wasler, A; Krumnikel, J; Gamillschegg, A; Knez, I.
Complication profile of the Berlin Heart EXCOR biventricular support in children.
Artif Organs. 2013; 37(8):730-735
Doi: 10.1111/aor.12062
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Schweiger Martin
- Co-Autor*innen der Med Uni Graz
- Gamillscheg Andreas
- Knez Igor
- Krumnikl Jakub
- Prenner Günther
- Sereinigg Michael
- Tscheliessnigg Karlheinz
- Wasler Andrae
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- Abstract:
- In chronic cardiomyopathy, mechanical circulatory support (MCS) plays an increasingly important role for children as the shortage of suitable donor hearts increases waiting time on the transplant list. We report our experience with the paracorporal Berlin Heart EXCOR System (Berlin Heart AG, Berlin, Germany) used as a biventricuclar assist device (BVAD). Nine patients with a BVAD EXCOR system were treated between 2006 and 2012; out of these patients, four were less than 18 years old (6, 14, 14, and 17 years old). Their diagnoses were postcardotomy failure (n = 1), dilatative cardiomyopathy (n = 2), and terminal heart failure (n = 1). Overall survival, waiting time for heart transplantation (HTx) and complication profile for the BVAD were analyzed retrospectively. Thirty days' mortality was 25% (n = 1). One child died after 84 days on support due to cerebral bleeding. Mean support time was 218.75 days (4, 84, 262, and 525 days). Pump chamber exchange was necessary three times due to pump chamber thrombosis (n = 2) and partial pump chamber membrane rupture (n = 1). Complications included: sepsis (n = 1), drive line infection requiring intravenous antibiotics (n = 2), and recurrent epistaxis (n = 3). Two children were successfully transplanted after 262/525 days on BVAD; they are currently at home (follow-up: 1.9 and 2.3 years). The EXCOR is a life-saving MCS system suitable for long-term paracorporeal biventricular assistance. © 2013, Copyright the Authors. Artificial Organs © 2013 Wiley Periodicals, Inc. and International Center for Artificial Organs and Transplantation.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Aged -
- Cardiomyopathy, Dilated - surgery
- Cerebral Hemorrhage - etiology
- Child -
- Epistaxis - etiology
- Heart Failure - surgery
- Heart-Assist Devices - adverse effects
- Hemorrhage - etiology
- Humans -
- Middle Aged -
- Sepsis - etiology
- Treatment Outcome -
- Young Adult -
- Find related publications in this database (Keywords)
- Children
- Biventricular heart failure
- EXCOR
- Berlin Heart