Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Gebauer, D; Fink, A; Kargl, R; Reishofer, G; Koschutnig, K; Purgstaller, C; Fazekas, F; Enzinger, C.
Differences in brain function and changes with intervention in children with poor spelling and reading abilities.
PLoS One. 2012; 7(5):e38201-e38201
Doi: 10.1371/journal.pone.0038201
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- Führende Autor*innen der Med Uni Graz
- Pinter Daniela Theresia
- Co-Autor*innen der Med Uni Graz
- Enzinger Christian
- Fazekas Franz
- Koschutnig Karl
- Reishofer Gernot
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- Abstract:
- Previous fMRI studies in English-speaking samples suggested that specific interventions may alter brain function in language-relevant networks in children with reading and spelling difficulties, but this research strongly focused on reading impaired individuals. Only few studies so far investigated characteristics of brain activation associated with poor spelling ability and whether a specific spelling intervention may also be associated with distinct changes in brain activity patterns. We here investigated such effects of a morpheme-based spelling intervention on brain function in 20 children with comparatively poor spelling and reading abilities using repeated fMRI. Relative to 10 matched controls, children with comparatively poor spelling and reading abilities showed increased activation in frontal medial and right hemispheric regions and decreased activation in left occipito-temporal regions prior to the intervention, during processing of a lexical decision task. After five weeks of intervention, spelling and reading comprehension significantly improved in the training group, along with increased activation in the left temporal, parahippocampal and hippocampal regions. Conversely, the waiting group showed increases in right posterior regions. Our findings could indicate an increased left temporal activation associated with the recollection of the new learnt morpheme-based strategy related to successful training.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Behavior - physiology
- Brain - physiopathology
- Case-Control Studies -
- Child -
- Female -
- Humans -
- Magnetic Resonance Imaging -
- Male -
- Reading -