Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
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Rödl, S; Resch, B; Hofer, N; Marschitz, I; Madler, G; Eber, E; Zobel, G.
Prospective evaluation of clinical scoring systems in infants with bronchiolitis admitted to the intensive care unit.
Eur J Clin Microbiol Infect Dis. 2012; 31(10):2667-2672
Doi: 10.1007/s10096-012-1612-z
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- Führende Autor*innen der Med Uni Graz
- Resch Bernhard
- Roedl Siegfried
- Co-Autor*innen der Med Uni Graz
- Eber Ernst
- Hofer Nora
- Zobel Gerfried
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- Abstract:
- The objective of this investigation was to compare different scoring systems to assess the severity of illness in infants with bronchiolitis admitted to a tertiary paediatric intensive care unit (PICU). Over an 18-year period (1990-2007), infants with bronchiolitis aged up to 12 months and admitted to the PICU were prospectively scored using the Pediatric Risk of Mortality III (PRISM III) score, the Organ System Failure (OSF) score and the Acute Physiologic Score for Children (APSC) within 24 h. Infants were compared as to whether or not bronchiolitis was associated with respiratory syncytial virus (RSV). There was no difference between 113 RSV-positive and 80 RSV-negative infants regarding gestational age, birth weight, rate of premature delivery or bronchopulmonary dysplasia (BPD). The PRISM III score differed significantly between RSV-positive and RSV-negative cases (3.27 ± 0.39 vs. 1.96 ± 0.44, p = 0.006), as did the OSF score (0.56 ± 0.05 vs. 0.35 ± 0.06, p = 0.049) and the APSC (5.16 ± 0.46 vs. 4.1 ± 0.53, p = 0.048). All scores were significantly higher in the subgroup with mechanical ventilation (p < 0.0001). The mean time of ventilation was significantly higher in the RSV-positive group compared to the RSV-negative group (6.39 ± 1.74 days vs. 2.4 ± 0.47 days, p < 0.001). Infants suffering from RSV-positive bronchiolitis had higher clinical scores corresponding with the severity of bronchiolitis.
- Find related publications in this database (using NLM MeSH Indexing)
- Birth Weight -
- Bronchiolitis - pathology
- Bronchopulmonary Dysplasia - diagnosis
- Gestational Age -
- Humans -
- Infant -
- Infant, Newborn -
- Infant, Premature -
- Intensive Care Units, Pediatric - standards
- Prospective Studies -
- ROC Curve -
- Respiration, Artificial -
- Respiratory Syncytial Virus Infections - diagnosis
- Respiratory Syncytial Viruses - pathogenicity
- Sensitivity and Specificity -
- Severity of Illness Index -
- Time Factors -