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Fröhlich-Reiterer, EE; Borkenstein, MH.
Microvascular and macrovascular complications in children and adolescents with type 1 diabetes mellitus.
Wien Med Wochenschr. 2010; 160(15-16): 414-418. Doi: 10.1007/s10354-010-0816-z
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Führende Autor*innen der Med Uni Graz
Fröhlich-Reiterer Elke
Co-Autor*innen der Med Uni Graz
Borkenstein Helmuth Martin
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Abstract:
Diabetes-related microvascular and macrovascular complications, as retinopathy, nephropathy and neuropathy are life-threatening complications in children and adolescents with type 1 diabetes mellitus (T1DM). Risk factors for the development of complications are longer duration of diabetes, older age and puberty. Further risk factors include smoking, hypertension, higher body mass index and dyslipoproteinaemia. Therefore prevention and screening for complications is an important part in the care of children and adolescents with T1DM. Target levels to reduce the risk of microvascular and macrovascular complications in children and adolescents with T1DM are the following: HbA1c<7.5%, lipids in normal range, blood pressure<90th percentile by age, sex and height, BMI<95th percentile, no smoking and physical activity. Screening for retinopathy and microalbuminuria should start from 11 years with two years diabetes duration and from 9 years with 5 years duration and after 2 years diabetes duration in an adolescent. Thereafter screening should be performed annually. Blood pressure should be measured at least annually. Screening for fasting blood lipids should be performed soon after diagnosis in all children with T1DM aged over 12 years. If normal results are obtained, this should be repeated every 5 years.
Find related publications in this database (using NLM MeSH Indexing)
Adolescent -
Age Factors -
Blood Pressure -
Body Mass Index -
Child -
Diabetes Mellitus, Type 1 - diagnosis
Diabetic Angiopathies - diagnosis
Diabetic Nephropathies - diagnosis
Diabetic Neuropathies - diagnosis
Diabetic Retinopathy - diagnosis
Female -
Hemoglobin A, Glycosylated - metabolism
Humans -
Lipids - blood
Mass Screening -
Motor Activity -
Risk Factors -
Smoking - adverse effects

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