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Search Items: BRAF, . hits: 89

2020

Reichmann, F; Rimmer, N; Tilley, CA; Dalla Vecchia, E; Pinion, J; Al Oustah, A; Carreño Gutiérrez, H; Young, AMJ; McDearmid, JR; Winter, MJ; Norton, WHJ The zebrafish histamine H3 receptor modulates aggression, neural activity and forebrain functional connectivity.
Acta Physiol (Oxf). 2020; e13543-e13543
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Stallinger, A; Kretschmer, N; Kleinegger, F; Brvar, L; Liegl-Atzwanger, B; Prokesch, A; Durchschein, C; Bauer, R; Deutsch, A; Rinner, B β,β-Dimethylacrylshikonin Induces Apoptosis in Melanoma Cell Lines by NOXA Upregulation.
J Nat Prod. 2020; 83(2):305-315
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Woltsche, N; Kruger, MA; Weger, M; Wolf, IH; Seidel, G Intravitreal Steroid Treatment for Uveitis Associated with Dabrafenib and Trametinib for Metastatic Cutaneous Melanoma.
Ocul Immunol Inflamm. 2020; 1-3.
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2019

Carreño Gutiérrez, H; Colanesi, S; Cooper, B; Reichmann, F; Young, AMJ; Kelsh, RN; Norton, WHJ Endothelin neurotransmitter signalling controls zebrafish social behaviour.
Sci Rep. 2019; 9(1): 3040-3040. [OPEN ACCESS]
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Franck, C; Rosania, R; Franke, S; Haybaeck, J; Canbay, A; Venerito, M The BRAF Status May Predict Response to Sorafenib in Gastrointestinal Stromal Tumors Resistant to Imatinib, Sunitinib, and Regorafenib: Case Series and Review of the Literature.
Digestion. 2019; 99(2):179-184
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Liebs, S; Keilholz, U; Kehler, I; Schweiger, C; Haybäck, J; Nonnenmacher, A Detection of mutations in circulating cell-free DNA in relation to disease stage in colorectal cancer.
Cancer Med. 2019; 8(8):3761-3769 [OPEN ACCESS]
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Margonis, GA; Buettner, S; Andreatos, N; Wagner, D; Sasaki, K; Barbon, C; Beer, A; Kamphues, C; Løes, IM; He, J; Pawlik, TM; Kaczirek, K; Poultsides, G; Lønning, PE; Cameron, JL; Mischinger, HJ; Aucejo, FN; Kreis, ME; Wolfgang, CL; Weiss, MJ Prognostic Factors Change Over Time After Hepatectomy for Colorectal Liver Metastases: A Multi-institutional, International Analysis of 1099 Patients.
ANN SURG. 2019; 269(6): 1129-1137.
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Norton, WHJ; Manceau, L; Reichmann, F The Visually Mediated Social Preference Test: A Novel Technique to Measure Social Behavior and Behavioral Disturbances in Zebrafish.
Methods Mol Biol. 2019; 2011: 121-132.
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Smolle, MA; Kashofer, K; Riedl, JM; Stotz, M; Gerger, A Genetic Analysis Using a Gene Panel in 87 Caucasian Patients With Colorectal Cancer: Own Results and Review of Literature.
Anticancer Res. 2019; 39(2): 847-852.
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Totsch, M; Schmid, KW Impact on the assessment of fine needle biopsy of the thyroid after the introduction of NIFTP
ONKOLOGE. 2019; 25(7): 590-595.
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2018

Berger, AW; Raedler, K; Langner, C; Ludwig, L; Dikopoulos, N; Becker, KF; Slotta-Huspenina, J; Quante, M; Schwerdel, D; Perkhofer, L; Kleger, A; Zizer, E; Oswald, F; Seufferlein, T; Meining, A Genetic Biopsy for Prediction of Surveillance Intervals after Endoscopic Resection of Colonic Polyps: Results of the GENESIS Study.
United European Gastroenterol J. 2018; 6(2): 290-299. [OPEN ACCESS]
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Berger, M; Richtig, G; Kashofer, K; Aigelsreiter, A; Richtig, E The window of opportunities for targeted therapy in BRAFwt/NRASwt/KITwt melanoma: biology and clinical implications of fusion proteins and other mutations.
G Ital Dermatol Venereol. 2018; 153(3): 349-360. [OPEN ACCESS]
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Deshwar, A; Margonis, GA; Andreatos, N; Barbon, C; Wang, J; Buettner, S; Wagner, D; Sasaki, K; Beer, A; Løes, IM; Pikoulis, E; Damaskos, C; Garmpis, N; Kamphues, K; He, J; Kaczirek, K; Poultsides, G; Lønning, PE; Mischinger, HJ; Aucejo, FN; Kreis, ME; Wolfgang, CL; Weiss, MJ Double KRAS and BRAF Mutations in Surgically Treated Colorectal Cancer Liver Metastases: An International, Multi-institutional Case Series.
Anticancer Res. 2018; 38(5):2891-2895 (- Case Report) [OPEN ACCESS]
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Hajek, E; Krebs, F; Bent, R; Haas, K; Bast, A; Steinmetz, I; Tuettenberg, A; Grabbe, S; Bros, M BRAF inhibitors stimulate inflammasome activation and interleukin 1 beta production in dendritic cells.
Oncotarget. 2018; 9(47): 28294-28308. [OPEN ACCESS]
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Margonis, GA; Buettner, S; Andreatos, N; Kim, Y; Wagner, D; Sasaki, K; Beer, A; Schwarz, C; Løes, IM; Smolle, M; Kamphues, C; He, J; Pawlik, TM; Kaczirek, K; Poultsides, G; Lønning, PE; Cameron, JL; Burkhart, RA; Gerger, A; Aucejo, FN; Kreis, ME; Wolfgang, CL; Weiss, MJ Association of BRAF Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer.
JAMA Surg. 2018; 153(7): e180996-e180996. [OPEN ACCESS]
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Margonis, GA; Buettner, S; Andreatos, N; Wagner, D; Sasaki, K; Barbon, C; Beer, A; Kamphues, C; Løes, IM; He, J; Pawlik, TM; Kaczirek, K; Poultsides, G; Lønning, PE; Cameron, JL; Mischinger, HJ; Aucejo, FN; Kreis, ME; Wolfgang, CL; Weiss, MJ Prognostic Factors Change Over Time After Hepatectomy for Colorectal Liver Metastases: A Multi-institutional, International Analysis of 1099 Patients.
Ann Surg. 2018;
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Posch, F; Silina, K; Leibl, S; Mündlein, A; Moch, H; Siebenhüner, A; Samaras, P; Riedl, J; Stotz, M; Szkandera, J; Stöger, H; Pichler, M; Stupp, R; van den Broek, M; Schraml, P; Gerger, A; Petrausch, U; Winder, T Maturation of tertiary lymphoid structures and recurrence of stage II and III colorectal cancer.
Oncoimmunology. 2018; 7(2):e1378844-e1378844 [OPEN ACCESS]
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Saraggi, D; Salmaso, R; Zamuner, C; Munari, G; Lanza, C; Alaibac, MS; Bassetto, F; Rugge, M; Montesco, MC; Cerroni, L; Fassan, M Prevalence of ALK gene alterations among the spectrum of plexiform spitzoid lesions.
J Am Acad Dermatol. 2018; 79(4):728-735
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Veatch, JR; Lee, SM; Fitzgibbon, M; Chow, IT; Jesernig, B; Schmitt, T; Kong, YY; Kargl, J; Houghton, AM; Thompson, JA; McIntosh, M; Kwok, WW; Riddell, SR Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma.
J CLIN INVEST. 2018; 128(4): 1563-1568. [OPEN ACCESS]
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Zhou, XA; Louissaint, A; Wenzel, A; Yang, J; Martinez-Escala, ME; Moy, AP; Morgan, EA; Paxton, CN; Hong, B; Andersen, EF; Guitart, J; Behdad, A; Cerroni, L; Weinstock, DM; Choi, J Genomic Analyses Identify Recurrent Alterations in Immune Evasion Genes in Diffuse Large B-Cell Lymphoma, Leg Type.
J INVEST DERMATOL. 2018; 138(11): 2365-2376. [OPEN ACCESS]
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2017

Fakhruddin, N; Jabbour, M; Novy, M; Tamim, H; Bahmad, H; Farhat, F; Zaatari, G; Aridi, T; Kriegshauser, G; Oberkanins, C; Mahfouz, R BRAF and NRAS Mutations in Papillary Thyroid Carcinoma and Concordance in BRAF Mutations Between Primary and Corresponding Lymph Node Metastases.
Sci Rep. 2017; 7(1):4666-4666 [OPEN ACCESS]
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Heitzer, E; Sunitsch, S; Gilg, MM; Lohberger, B; Rinner, B; Kashofer, K; Stündl, N; Ulz, P; Szkandera, J; Leithner, A; Liegl-Atzwanger, B Expanded molecular profiling of myxofibrosarcoma reveals potentially actionable targets.
Mod Pathol. 2017; 30(12):1698-1709 [OPEN ACCESS]
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Kandolf Sekulovic, L; Peris, K; Hauschild, A; Stratigos, A; Grob, JJ; Nathan, P; Dummer, R; Forsea, AM; Hoeller, C; Gogas, H; Demidov, L; Lebbe, C; Blank, C; Olah, J; Bastholt, L; Herceg, D; Neyns, B; Vieira, R; Hansson, J; Rutkowski, P; Krajsova, I; Bylaite-Bucinskiene, M; Zalaudek, I; Maric-Brozic, J; Babovic, N; Banjin, M; Putnik, K; Weinlich, G; Todorovic, V; Kirov, K; Ocvirk, J; Zhukavets, A; Kukushkina, M; De La Cruz Merino, L; Ymeri, A; Risteski, M; Garbe, C More than 5000 patients with metastatic melanoma in Europe per year do not have access to recommended first-line innovative treatments.
Eur J Cancer. 2017; 75(4):313-322
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Möller, I; Murali, R; Müller, H; Wiesner, T; Jackett, LA; Scholz, SL; Cosgarea, I; van de Nes, JA; Sucker, A; Hillen, U; Schilling, B; Paschen, A; Kutzner, H; Rütten, A; Böckers, M; Scolyer, RA; Schadendorf, D; Griewank, KG Activating cysteinyl leukotriene receptor 2 (CYSLTR2) mutations in blue nevi.
Mod Pathol. 2017; 30(3):350-356 [OPEN ACCESS]
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Ofner, R; Ritter, C; Heidenreich, B; Kumar, R; Ugurel, S; Schrama, D; Becker, JC Distribution of TERT promoter mutations in primary and metastatic melanomas in Austrian patients.
J Cancer Res Clin Oncol. 2017; 143(4):613-617 [OPEN ACCESS]
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Richtig, G; Hoeller, C; Kashofer, K; Aigelsreiter, A; Heinemann, A; Kwong, LN; Pichler, M; Richtig, E Beyond the BRAFV600E hotspot: biology and clinical implications of rare BRAF gene mutations in melanoma patients.
Br J Dermatol. 2017; 177(4):936-944
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Rinner, B; Gandolfi, G; Meditz, K; Frisch, MT; Wagner, K; Ciarrocchi, A; Torricelli, F; Koivuniemi, R; Niklander, J; Liegl-Atzwanger, B; Lohberger, B; Heitzer, E; Ghaffari-Tabrizi-Wizsy, N; Zweytick, D; Zalaudek, I MUG-Mel2, a novel highly pigmented and well characterized NRAS mutated human melanoma cell line.
Sci Rep. 2017; 7(1):2098-2098 [OPEN ACCESS]
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Roh-Johnson, M; Shah, AN; Stonick, JA; Poudel, KR; Kargl, J; Yang, GH; di Martino, J; Hernandez, RE; Gast, CE; Zarour, LR; Antoku, S; Houghton, AM; Bravo-Cordero, JJ; Wong, MH; Condeelis, J; Moens, CB Macrophage-Dependent Cytoplasmic Transfer during Melanoma Invasion In Vivo.
Dev Cell. 2017; 43(5):549-562 [OPEN ACCESS]
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Saraggi, D; Salmaso, R; Valentini, E; Munari, G; Vindigni, V; Rugge, M; Fassan, M; Cerroni, L Pigmented trichoblastoma developed in a sebaceous nevus: HRAS mutation as a common molecular driver.
Pathol Res Pract. 2017; 213(7):860-862 (- Case Report)
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Sarny, S; Neumayer, M; Kofler, J; El-Shabrawi, Y Ocular toxicity due to Trametinib and Dabrafenib.
BMC Ophthalmol. 2017; 17(1):146-146 (- Case Report) [OPEN ACCESS]
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van Rooij, FJ; Qayyum, R; Smith, AV; Zhou, Y; Trompet, S; Tanaka, T; Keller, MF; Chang, LC; Schmidt, H; Yang, ML; Chen, MH; Hayes, J; Johnson, AD; Yanek, LR; Mueller, C; Lange, L; Floyd, JS; Ghanbari, M; Zonderman, AB; Jukema, JW; Hofman, A; van Duijn, CM; Desch, KC; Saba, Y; Ozel, AB; Snively, BM; Wu, JY; Schmidt, R; Fornage, M; Klein, RJ; Fox, CS; Matsuda, K; Kamatani, N; Wild, PS; Stott, DJ; Ford, I; Slagboom, PE; Yang, J; Chu, AY; Lambert, AJ; Uitterlinden, AG; Franco, OH; Hofer, E; Ginsburg, D; Hu, B; Keating, B; Schick, UM; Brody, JA; Li, JZ; Chen, Z; Zeller, T; Guralnik, JM; Chasman, DI; Peters, LL; Kubo, M; Becker, DM; Li, J; Eiriksdottir, G; Rotter, JI; Levy, D; Grossmann, V; Patel, KV; Chen, CH; BioBank Japan Project; Ridker, PM; Tang, H; Launer, LJ; Rice, KM; Li-Gao, R; Ferrucci, L; Evans, MK; Choudhuri, A; Trompouki, E; Abraham, BJ; Yang, S; Takahashi, A; Kamatani, Y; Kooperberg, C; Harris, TB; Jee, SH; Coresh, J; Tsai, FJ; Longo, DL; Chen, YT; Felix, JF; Yang, Q; Psaty, BM; Boerwinkle, E; Becker, LC; Mook-Kanamori, DO; Wilson, JG; Gudnason, V; O'Donnell, CJ; Dehghan, A; Cupples, LA; Nalls, MA; Morris, AP; Okada, Y; Reiner, AP; Zon, LI; Ganesh, SK Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.
Am J Hum Genet. 2017; 100(1): 51-63. [OPEN ACCESS]
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Yeh, I; Lang, UE; Durieux, E; Tee, MK; Jorapur, A; Shain, AH; Haddad, V; Pissaloux, D; Chen, X; Cerroni, L; Judson, RL; LeBoit, PE; McCalmont, TH; Bastian, BC; de la Fouchardière, A Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi.
Nat Commun. 2017; 8(1):644-644 [OPEN ACCESS]
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2016

Busam, KJ; Vilain, RE; Lum, T; Busam, JA; Hollmann, TJ; Saw, RP; Coit, DC; Scolyer, RA; Wiesner, T Primary and Metastatic Cutaneous Melanomas Express ALK Through Alternative Transcriptional Initiation.
Am J Surg Pathol. 2016; 40(6):786-795 [OPEN ACCESS]
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Dernayka, L; Rauch, N; Jarboui, MA; Zebisch, A; Texier, Y; Horn, N; Romano, D; Gloeckner, CJ; Kriegsheim, Av; Ueffing, M; Kolch, W; Boldt, K Autophosphorylation on S614 inhibits the activity and the transforming potential of BRAF.
Cell Signal. 2016; 28(9):1432-1439
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Kiuru, M; Jungbluth, A; Kutzner, H; Wiesner, T; Busam, KJ Spitz Tumors: Comparison of Histological Features in Relationship to Immunohistochemical Staining for ALK and NTRK1.
Int J Surg Pathol. 2016; 24(3):200-206
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Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, the Stroke Genetics Network (SiGN), and the International Stroke Genetics Consortium (ISGC) Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies.
Lancet Neurol. 2016; 15(7):695-707 [OPEN ACCESS]
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Ribero, S; Pampena, R; Bataille, V; Moscarella, E; Thomas, L; Quaglino, P; Potenza, C; Van Akkooi, ACJ; Testori, A; Nathan, P; Puig, S; Zalaudek, I; Argenziano, G; Longo, C Unknown Primary Melanoma: Worldwide Survey on Clinical Management.
Dermatology. 2016; 232(6):704-707 [OPEN ACCESS]
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Richtig, G; Aigelsreiter, A; Kashofer, K; Talakic, E; Kupsa, R; Schaider, H; Richtig, E Two Case Reports of Rare BRAF Mutations in Exon 11 and Exon 15 with Discussion of Potential Treatment Options.
Case Rep Oncol. 2016; 9(3):543-546 [OPEN ACCESS]
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Scheipl, S; Barnard, M; Cottone, L; Jorgensen, M; Drewry, DH; Zuercher, WJ; Turlais, F; Ye, H; Leite, AP; Smith, JA; Leithner, A; Möller, P; Brüderlein, S; Guppy, N; Amary, F; Tirabosco, R; Strauss, SJ; Pillay, N; Flanagan, AM EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen.
J Pathol. 2016; 239(3):320-334 [OPEN ACCESS]
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van de Nes, J; Gessi, M; Sucker, A; Möller, I; Stiller, M; Horn, S; Scholz, SL; Pischler, C; Stadtler, N; Schilling, B; Zimmer, L; Hillen, U; Scolyer, RA; Buckland, ME; Lauriola, L; Pietsch, T; Waha, A; Schadendorf, D; Murali, R; Griewank, KG Targeted next generation sequencing reveals unique mutation profile of primary melanocytic tumors of the central nervous system.
J NEURO-ONCOL. 2016; 127(3): 435-444. [OPEN ACCESS]
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Wiesner, T; Kutzner, H; Cerroni, L; Mihm, MC; Busam, KJ; Murali, R Genomic aberrations in spitzoid melanocytic tumours and their implications for diagnosis, prognosis and therapy.
Pathology. 2016; 48(2):113-131 [OPEN ACCESS]
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2015

Gorski, M; Tin, A; Garnaas, M; McMahon, GM; Chu, AY; Tayo, BO; Pattaro, C; Teumer, A; Chasman, DI; Chalmers, J; Hamet, P; Tremblay, J; Woodward, M; Aspelund, T; Eiriksdottir, G; Gudnason, V; Harris, TB; Launer, LJ; Smith, AV; Mitchell, BD; O'Connell, JR; Shuldiner, AR; Coresh, J; Li, M; Freudenberger, P; Hofer, E; Schmidt, H; Schmidt, R; Holliday, EG; Mitchell, P; Wang, JJ; de Boer, IH; Li, G; Siscovick, DS; Kutalik, Z; Corre, T; Vollenweider, P; Waeber, G; Gupta, J; Kanetsky, PA; Hwang, SJ; Olden, M; Yang, Q; de Andrade, M; Atkinson, EJ; Kardia, SL; Turner, ST; Stafford, JM; Ding, J; Liu, Y; Barlassina, C; Cusi, D; Salvi, E; Staessen, JA; Ridker, PM; Grallert, H; Meisinger, C; Müller-Nurasyid, M; Krämer, BK; Kramer, H; Rosas, SE; Nolte, IM; Penninx, BW; Snieder, H; Fabiola Del Greco, M; Franke, A; Nöthlings, U; Lieb, W; Bakker, SJ; Gansevoort, RT; van der Harst, P; Dehghan, A; Franco, OH; Hofman, A; Rivadeneira, F; Sedaghat, S; Uitterlinden, AG; Coassin, S; Haun, M; Kollerits, B; Kronenberg, F; Paulweber, B; Aumann, N; Endlich, K; Pietzner, M; Völker, U; Rettig, R; Chouraki, V; Helmer, C; Lambert, JC; Metzger, M; Stengel, B; Lehtimäki, T; Lyytikäinen, LP; Raitakari, O; Johnson, A; Parsa, A; Bochud, M; Heid, IM; Goessling, W; Köttgen, A; Kao, WH; Fox, CS; Böger, CA Genome-wide association study of kidney function decline in individuals of European descent.
Kidney Int. 2015; 87(5):1017-1029 [OPEN ACCESS]
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Jahn, SW; Kashofer, K; Halbwedl, I; Winter, G; El-Shabrawi-Caelen, L; Mentzel, T; Hoefler, G; Liegl-Atzwanger, B Mutational dichotomy in desmoplastic malignant melanoma corroborated by multigene panel analysis.
Mod Pathol. 2015; 28(7):895-903 [OPEN ACCESS]
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Kaczirek, K; Ciuleanu, TE; Vrbanec, D; Marton, E; Messinger, D; Liegl-Atzwanger, B; Wrba, F; Knittelfelder, R; Lindner, E; Zielinski, CC; Streubel, B; Brodowicz, T FOLFOX4 Plus Cetuximab for Patients With Previously Untreated Metastatic Colorectal Cancer According to Tumor RAS and BRAF Mutation Status: Updated Analysis of the CECOG/CORE 1.2.002 Study.
Clin Colorectal Cancer. 2015; 14(2):91-98
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Langner, C Serrated and non-serrated precursor lesions of colorectal cancer.
Dig Dis. 2015; 33(1):28-37
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Milewska, M; Romano, D; Herrero, A; Guerriero, ML; Birtwistle, M; Quehenberger, F; Hatzl, S; Kholodenko, BN; Segatto, O; Kolch, W; Zebisch, A Mitogen-Inducible Gene-6 Mediates Feedback Inhibition from Mutated BRAF towards the Epidermal Growth Factor Receptor and Thereby Limits Malignant Transformation.
PLoS One. 2015; 10(6):e0129859-e0129859 [OPEN ACCESS]
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Mössner, R; Zimmer, L; Berking, C; Hoeller, C; Loquai, C; Richtig, E; Kähler, KC; Hassel, JC; Gutzmer, R; Ugurel, S Erythema nodosum-like lesions during BRAF inhibitor therapy: Report on 16 new cases and review of the literature.
J Eur Acad Dermatol Venereol. 2015; 29(9):1797-1806 (- Case Report)
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Murali, R; Chandramohan, R; Möller, I; Scholz, SL; Berger, M; Huberman, K; Viale, A; Pirun, M; Socci, ND; Bouvier, N; Bauer, S; Artl, M; Schilling, B; Schimming, T; Sucker, A; Schwindenhammer, B; Grabellus, F; Speicher, MR; Schaller, J; Hillen, U; Schadendorf, D; Mentzel, T; Cheng, DT; Wiesner, T; Griewank, KG Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway.
Oncotarget. 2015; 6(34):36041-36052 [OPEN ACCESS]
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Obenauf, AC; Zou, Y; Ji, AL; Vanharanta, S; Shu, W; Shi, H; Kong, X; Bosenberg, MC; Wiesner, T; Rosen, N; Lo, RS; Massagué, J Therapy-induced tumour secretomes promote resistance and tumour progression.
Nature. 2015; 520(7547): 368-372. [OPEN ACCESS]
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Schwamb, B; Pick, R; Fernández, SB; Völp, K; Heering, J; Dötsch, V; Bösser, S; Jung, J; Beinoraviciute-Kellner, R; Wesely, J; Zörnig, I; Hammerschmidt, M; Nowak, M; Penzel, R; Zatloukal, K; Joos, S; Rieker, RJ; Agaimy, A; Söder, S; Reid-Lombardo, KM; Kendrick, ML; Bardsley, MR; Hayashi, Y; Asuzu, DT; Syed, SA; Ordog, T; Zörnig, M FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors.
Int J Cancer. 2015; 137(6):1318-1329 [OPEN ACCESS]
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