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Search Items: NF-KAPPA B - METABOLISM , . hits: 52

2022

Anand, U; Shteinfer-Kuzmine, A; Sela, G; Santhanam, M; Gottschalk, B; Boujemaa-Paterski, R; Medalia, O; Graier, WF; Shoshan-Barmatz, V The Multicellular Effects of VDAC1 N-Terminal-Derived Peptide.
Biomolecules. 2022; 12(10): Doi: 10.3390/biom12101387 [OPEN ACCESS]
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2019

Bärnthaler, T; Jandl, K; Sill, H; Uhl, B; Schreiber, Y; Grill, M; Thomas, D; Schicho, R; Marsche, G; Frank, S; Heinemann, A; Schuligoi, R Imatinib stimulates prostaglandin E₂ and attenuates cytokine release via EP4 receptor activation.
J Allergy Clin Immunol. 2019; 143(2):794-797 Doi: 10.1016/j.jaci.2018.09.030 [OPEN ACCESS]
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Kukolj, T; Trivanović, D; Mojsilović, S; Okić Djordjević, I; Obradović, H; Krstić, J; Jauković, A; Bugarski, D IL-33 guides osteogenesis and increases proliferation and pluripotency marker expression in dental stem cells.
Cell Prolif. 2019; 52(1): e12533-e12533. Doi: 10.1111/cpr.12533 [OPEN ACCESS]
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Runtsch, MC; Nelson, MC; Lee, SH; Voth, W; Alexander, M; Hu, R; Wallace, J; Petersen, C; Panic, V; Villanueva, CJ; Evason, KJ; Bauer, KM; Mosbruger, T; Boudina, S; Bronner, M; Round, JL; Drummond, MJ; O'Connell, RM Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease.
PLoS Genet. 2019; 15(2):e1007970 Doi: 10.1371/journal.pgen.1007970 [OPEN ACCESS]
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2018

Voelkl, J; Luong, TT; Tuffaha, R; Musculus, K; Auer, T; Lian, X; Daniel, C; Zickler, D; Boehme, B; Sacherer, M; Metzler, B; Kuhl, D; Gollasch, M; Amann, K; Müller, DN; Pieske, B; Lang, F; Alesutan, I SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling.
J Clin Invest. 2018; 128(7):3024-3040 Doi: 10.1172/JCI96477 [OPEN ACCESS]
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2017

Longtine, MS; Cvitic, S; Colvin, BN; Chen, B; Desoye, G; Nelson, DM Calcitriol regulates immune genes CD14 and CD180 to modulate LPS responses in human trophoblasts.
Reproduction. 2017; 154(6):735-744 Doi: 10.1530/REP-17-0183 [OPEN ACCESS]
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Mehta, AK; Hua, K; Whipple, W; Nguyen, MT; Liu, CT; Haybaeck, J; Weidhaas, J; Settleman, J; Singh, A Regulation of autophagy, NF-κB signaling, and cell viability by miR-124 in KRAS mutant mesenchymal-like NSCLC cells.
Sci Signal. 2017; 10(496): Doi: 10.1126/scisignal.aam6291 [OPEN ACCESS]
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2016

Hrdinka, M; Fiil, BK; Zucca, M; Leske, D; Bagola, K; Yabal, M; Elliott, PR; Damgaard, RB; Komander, D; Jost, PJ; Gyrd-Hansen, M CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling.
Cell Rep. 2016; 14(12):2846-2858 Doi: 10.1016/j.celrep.2016.02.062 [OPEN ACCESS]
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Modak, M; Majdic, O; Cejka, P; Jutz, S; Puck, A; Gerwien, JG; Steinberger, P; Zlabinger, GJ; Strobl, H; Stöckl, J Engagement of distinct epitopes on CD43 induces different co-stimulatory pathways in human T cells.
Immunology. 2016; 149(3):280-296 Doi: 10.1111/imm.12642 [OPEN ACCESS]
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Rolny, IS; Tiscornia, I; Racedo, SM; Pérez, PF; Bollati-Fogolín, M Lactobacillus delbrueckii subsp lactis CIDCA 133 modulates response of human epithelial and dendritic cells infected with Bacillus cereus.
Benef Microbes. 2016; 7(5):749-760 Doi: 10.3920/BM2015.0191
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2015

Antus, C; Radnai, B; Dombovari, P; Fonai, F; Avar, P; Matyus, P; Racz, B; Sumegi, B; Veres, B Anti-inflammatory effects of a triple-bond resveratrol analog: structure and function relationship.
Eur J Pharmacol. 2015; 748(3):61-67 Doi: 10.1016/j.ejphar.2014.12.009
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Grabner, B; Schramek, D; Mueller, KM; Moll, HP; Svinka, J; Hoffmann, T; Bauer, E; Blaas, L; Hruschka, N; Zboray, K; Stiedl, P; Nivarthi, H; Bogner, E; Gruber, W; Mohr, T; Zwick, RH; Kenner, L; Poli, V; Aberger, F; Stoiber, D; Egger, G; Esterbauer, H; Zuber, J; Moriggl, R; Eferl, R; Győrffy, B; Penninger, JM; Popper, H; Casanova, E Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis.
Nat Commun. 2015; 6(4):6285-6285 Doi: 10.1038/ncomms7285 [OPEN ACCESS]
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Holzer, M; Schilcher, G; Curcic, S; Trieb, M; Ljubojevic, S; Stojakovic, T; Scharnagl, H; Kopecky, CM; Rosenkranz, AR; Heinemann, A; Marsche, G Dialysis Modalities and HDL Composition and Function.
J Am Soc Nephrol. 2015; 26(9):2267-2276 Doi: 10.1681/ASN.2014030309 [OPEN ACCESS]
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Zanini, S; Giovinazzo, F; Alaimo, D; Lawrence, B; Pfragner, R; Bassi, C; Modlin, I; Kidd, M GNA15 expression in small intestinal neuroendocrine neoplasia: functional and signalling pathway analyses.
Cell Signal. 2015; 27(5):899-907 Doi: 10.1016/j.cellsig.2015.02.001
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2014

Balenga, NA; Martínez-Pinilla, E; Kargl, J; Schröder, R; Peinhaupt, M; Platzer, W; Bálint, Z; Zamarbide, M; Dopeso-Reyes, IG; Ricobaraza, A; Pérez-Ortiz, JM; Kostenis, E; Waldhoer, M; Heinemann, A; Franco, R Heteromerization of GPR55 and cannabinoid CB2 receptors modulates signalling.
Br J Pharmacol. 2014; 171(23):5387-5406 Doi: 10.1111/bph.12850 [OPEN ACCESS]
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Dorronsoro, A; Ferrin, I; Salcedo, JM; Jakobsson, E; Fernández-Rueda, J; Lang, V; Sepulveda, P; Fechter, K; Pennington, D; Trigueros, C Human mesenchymal stromal cells modulate T-cell responses through TNF-α-mediated activation of NF-κB.
Eur J Immunol. 2014; 44(2):480-488 Doi: 10.1002/eji.201343668 [OPEN ACCESS]
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Kiss, T; Kovacs, K; Komocsi, A; Tornyos, A; Zalan, P; Sumegi, B; Gallyas, F; Kovacs, K Novel mechanisms of sildenafil in pulmonary hypertension involving cytokines/chemokines, MAP kinases and Akt.
PLoS One. 2014; 9(8): e104890 Doi: 10.1371/journal.pone.0104890 [OPEN ACCESS]
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Liu, L; Salnikov, AV; Bauer, N; Aleksandrowicz, E; Labsch, S; Nwaeburu, C; Mattern, J; Gladkich, J; Schemmer, P; Werner, J; Herr, I Triptolide reverses hypoxia-induced epithelial-mesenchymal transition and stem-like features in pancreatic cancer by NF-κB downregulation.
Int J Cancer. 2014; 134(10):2489-2503 Doi: 10.1002/ijc.28583 [OPEN ACCESS]
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2013

Dorronsoro, A; Lang, V; Jakobsson, E; Ferrin, I; Salcedo, JM; Fernández-Rueda, J; Fechter, K; Rodriguez, MS; Trigueros, C Identification of the NF-κB inhibitor A20 as a key regulator for human adipogenesis.
Cell Death Dis. 2013; 4(1):e972-e972 Doi: 10.1038/cddis.2013.494 [OPEN ACCESS]
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Ho, JE; Chen, WY; Chen, MH; Larson, MG; McCabe, EL; Cheng, S; Ghorbani, A; Coglianese, E; Emilsson, V; Johnson, AD; Walter, S; Franceschini, N; O'Donnell, CJ; CARDIoGRAM Consortium; CHARGE Inflammation Working Group; Dehghan, A; Lu, C; Levy, D; Newton-Cheh, C; CHARGE Heart Failure Working Group; Lin, H; Felix, JF; Schreiter, ER; Vasan, RS; Januzzi, JL; Lee, RT; Wang, TJ; Assimes, TL; Deloukas, P; Erdmann, J; Holm, H; Kathiresan, S; König, IR; McPherson, R; Reilly, MP; Roberts, R; Samani, NJ; Schunkert, H; Stewart, AF Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling.
J Clin Invest. 2013; 123(10): 4208-4218. Doi: 10.1172/JCI67119 [OPEN ACCESS]
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Stradner, MH; Gruber, G; Angerer, H; Huber, V; Setznagl, D; Kremser, ML; Moazedi-Fürst, FC; Windhager, R; Graninger, WB Sphingosine 1-phosphate counteracts the effects of interleukin-1β in human chondrocytes.
Arthritis Rheum. 2013; 65(8):2113-2122 Doi: 10.1002/art.37989 [OPEN ACCESS]
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2012

El-Gamal, D; Holzer, M; Gauster, M; Schicho, R; Binder, V; Konya, V; Wadsack, C; Schuligoi, R; Heinemann, A; Marsche, G Cyanate is a novel inducer of endothelial icam-1 expression.
Antioxid Redox Signal. 2012; 16(2): 129-137. Doi: 10.1089/ars.2011.4090 [OPEN ACCESS]
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Oberbach, A; Schlichting, N; Heinrich, M; Till, H; Stolzenburg, JU; Neuhaus, J Free fatty acid palmitate impairs the vitality and function of cultured human bladder smooth muscle cells.
PLoS One. 2012; 7(7):e41026-e41026 Doi: 10.1371/journal.pone.0041026 [OPEN ACCESS]
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2011

Fiorotto, R; Scirpo, R; Trauner, M; Fabris, L; Hoque, R; Spirli, C; Strazzabosco, M Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-κB-mediated inflammatory response in mice.
Gastroenterology. 2011; 141(4): 1508.e1- 1508.e5 Doi: 10.1053/j.gastro.2011.06.052 [OPEN ACCESS]
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Motta, JP; Magne, L; Descamps, D; Rolland, C; Squarzoni-Dale, C; Rousset, P; Martin, L; Cenac, N; Balloy, V; Huerre, M; Fröhlich, LF; Jenne, D; Wartelle, J; Belaaouaj, A; Mas, E; Vinel, JP; Alric, L; Chignard, M; Vergnolle, N; Sallenave, JM Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis.
Gastroenterology. 2011; 140(4): 1272-1282. Doi: 10.1053/j.gastro.2010.12.050
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Riederer, M; Lechleitner, M; Hrzenjak, A; Koefeler, H; Desoye, G; Heinemann, A; Frank, S Endothelial lipase (EL) and EL-generated lysophosphatidylcholines promote IL-8 expression in endothelial cells.
Atherosclerosis. 2011; 214(2):338-344 Doi: 10.1016/j.atherosclerosis.2010.11.007 [OPEN ACCESS]
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Tucsek, Z; Radnai, B; Racz, B; Debreceni, B; Priber, JK; Dolowschiak, T; Palkovics, T; Gallyas, F; Sumegi, B; Veres, B Suppressing LPS-induced early signal transduction in macrophages by a polyphenol degradation product: a critical role of MKP-1.
J Leukoc Biol. 2011; 89(1):105-111 Doi: 10.1189/jlb.0610355 [OPEN ACCESS]
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2010

Bettermann, K; Vucur, M; Haybaeck, J; Koppe, C; Janssen, J; Heymann, F; Weber, A; Weiskirchen, R; Liedtke, C; Gassler, N; Müller, M; de Vos, R; Wolf, MJ; Boege, Y; Seleznik, GM; Zeller, N; Erny, D; Fuchs, T; Zoller, S; Cairo, S; Buendia, MA; Prinz, M; Akira, S; Tacke, F; Heikenwalder, M; Trautwein, C; Luedde, T TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer.
Cancer Cell. 2010; 17(5):481-496 Doi: 10.1016/j.ccr.2010.03.021 [OPEN ACCESS]
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Damm, S; Koefinger, P; Stefan, M; Wels, C; Mehes, G; Richtig, E; Kerl, H; Otte, M; Schaider, H HGF-promoted motility in primary human melanocytes depends on CD44v6 regulated via NF-kappa B, Egr-1, and C/EBP-beta.
J Invest Dermatol. 2010; 130(7): 1893-1903. Doi: 10.1038/jid.2010.45 [OPEN ACCESS]
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Missiou, A; Wolf, D; Platzer, I; Ernst, S; Walter, C; Rudolf, P; Zirlik, K; Köstlin, N; Willecke, FK; Münkel, C; Schönbeck, U; Libby, P; Bode, C; Varo, N; Zirlik, A CD40L induces inflammation and adipogenesis in adipose cells--a potential link between metabolic and cardiovascular disease.
THROMB HAEMOSTASIS. 2010; 103(4): 788-796. Doi: 10.1160/TH09-07-0463
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Rausch, V; Liu, L; Kallifatidis, G; Baumann, B; Mattern, J; Gladkich, J; Wirth, T; Schemmer, P; Büchler, MW; Zöller, M; Salnikov, AV; Herr, I Synergistic activity of sorafenib and sulforaphane abolishes pancreatic cancer stem cell characteristics.
Cancer Res. 2010; 70(12):5004-5013 Doi: 10.1158/0008-5472.CAN-10-0066 [OPEN ACCESS]
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Tschische, P; Moser, E; Thompson, D; Vischer, HF; Parzmair, GP; Pommer, V; Platzer, W; Schwarzbraun, T; Schaider, H; Smit, MJ; Martini, L; Whistler, JL; Waldhoer, M The G-protein coupled receptor associated sorting protein GASP-1 regulates the signalling and trafficking of the viral chemokine receptor US28.
Traffic. 2010; 11(5):660-674 Doi: 10.1111/j.1600-0854.2010.1045.x [OPEN ACCESS]
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Vucur, M; Roderburg, C; Bettermann, K; Tacke, F; Heikenwalder, M; Trautwein, C; Luedde, T Mouse models of hepatocarcinogenesis: what can we learn for the prevention of human hepatocellular carcinoma?
Oncotarget. 2010; 1(5):373-378 Doi: 10.18632/oncotarget.170 [OPEN ACCESS]
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2009

Kallifatidis, G; Rausch, V; Baumann, B; Apel, A; Beckermann, BM; Groth, A; Mattern, J; Li, Z; Kolb, A; Moldenhauer, G; Altevogt, P; Wirth, T; Werner, J; Schemmer, P; Büchler, MW; Salnikov, AV; Herr, I Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling.
Gut. 2009; 58(7):949-963 Doi: 10.1136/gut.2008.149039
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Krejsgaard, T; Vetter-Kauczok, CS; Woetmann, A; Kneitz, H; Eriksen, KW; Lovato, P; Zhang, Q; Wasik, MA; Geisler, C; Ralfkiaer, E; Becker, JC; Odum, N Ectopic expression of B-lymphoid kinase in cutaneous T-cell lymphoma.
Blood. 2009; 113(23):5896-5904 Doi: 10.1182/blood-2008-09-181024 [OPEN ACCESS]
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Li, Z; Nickkholgh, A; Yi, X; Bruns, H; Gross, ML; Hoffmann, K; Mohr, E; Zorn, M; Büchler, MW; Schemmer, P Melatonin protects kidney grafts from ischemia/reperfusion injury through inhibition of NF-kB and apoptosis after experimental kidney transplantation.
J Pineal Res. 2009; 46(4):365-372 Doi: 10.1111/j.1600-079X.2009.00672.x
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Radnai, B; Tucsek, Z; Bognar, Z; Antus, C; Mark, L; Berente, Z; Gallyas, F; Sumegi, B; Veres, B Ferulaldehyde, a water-soluble degradation product of polyphenols, inhibits the lipopolysaccharide-induced inflammatory response in mice.
J Nutr. 2009; 139(2): 291-297. Doi: 10.3945/jn.108.097386 [OPEN ACCESS]
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2007

Gattenloehner, S; Chuvpilo, S; Langebrake, C; Reinhardt, D; Muller-Hermelink, HK; Serfling, E; Vincent, A; Marx, A Novel RUNX1 isoforms determine the fate of acute myeloid leukemia cells by controlling CD56 expression.
Blood. 2007; 110(6):2027-2033 Doi: 10.1182/blood-2007-02-074203 [OPEN ACCESS]
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Hochegger, K; Perco, P; Enrich, J; Mayer, B; Mayer, G; Rosenkranz, AR; Rudnicki, M In vitro--transcriptional response of polymorphonuclear leukocytes following contact with different antigens.
Eur J Clin Invest. 2007; 37(11):860-869 Doi: 10.1111/j.1365-2362.2007.01872.x
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Jost, PJ; Weiss, S; Ferch, U; Gross, O; Mak, TW; Peschel, C; Ruland, J Bcl10/Malt1 signaling is essential for TCR-induced NF-kappaB activation in thymocytes but dispensable for positive or negative selection.
J Immunol. 2007; 178(2):953-960 Doi: 10.4049/jimmunol.178.2.953 [OPEN ACCESS]
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2006

Isoda, K; Young, JL; Zirlik, A; MacFarlane, LA; Tsuboi, N; Gerdes, N; Schönbeck, U; Libby, P Metformin inhibits proinflammatory responses and nuclear factor-kappaB in human vascular wall cells.
ARTERIOSCL THROM VAS. 2006; 26(3): 611-617. Doi: 10.1161/01.ATV.0000201938.78044.75 [OPEN ACCESS]
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Rust, C; Bauchmuller, K; Bernt, C; Vennegeerts, T; Fickert, P; Fuchsbichler, A; Beuers, U Sulfasalazine reduces bile acid induced apoptosis in human hepatoma cells and perfused rat livers.
GUT. 2006; 55(5): 719-727. Doi: 10.1136/gut.2005.077461 [OPEN ACCESS]
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Weber-Mzell, D; Zaupa, P; Petnehazy, T; Kobayashi, H; Schimpl, G; Feierl, G; Kotanko, P; Höllwarth, M The role of nuclear factor-kappa B in bacterial translocation in cholestatic rats.
Pediatr Surg Int. 2006; 22(1):43-49 Doi: 10.1007/s00383-005-1599-y
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2005

Schaefer, L; Babelova, A; Kiss, E; Hausser, HJ; Baliova, M; Krzyzankova, M; Marsche, G; Young, MF; Mihalik, D; Götte, M; Malle, E; Schaefer, RM; Gröne, HJ The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages.
J Clin Invest. 2005; 115(8): 2223-2233. Doi: 10.1172/JCI23755 [OPEN ACCESS]
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2004

Veres, B; Radnai, B; Gallyas, F; Varbiro, G; Berente, Z; Osz, E; Sumegi, B Regulation of kinase cascades and transcription factors by a poly(ADP-ribose) polymerase-1 inhibitor, 4-hydroxyquinazoline, in lipopolysaccharide-induced inflammation in mice.
J Pharmacol Exp Ther. 2004; 310(1): 247-255. Doi: 10.1124/jpet.104.065151
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2003

Egger, T; Schuligoi, R; Wintersperger, A; Amann, R; Malle, E; Sattler, W Vitamin E (alpha-tocopherol) attenuates cyclo-oxygenase 2 transcription and synthesis in immortalized murine BV-2 microglia.
BIOCHEM J 2003 370: 459-467. Doi: 10.1042/BJ20021358 [OPEN ACCESS]
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Pfeifhofer, C; Kofler, K; Gruber, T; Tabrizi, NG; Lutz, C; Maly, K; Leitges, M; Baier, G Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells.
J Exp Med. 2003; 197(11):1525-1535 Doi: 10.1084/jem.20020234 [OPEN ACCESS]
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2002

Bochkov, VN; Mechtcheriakova, D; Lucerna, M; Huber, J; Malli, R; Graier, WF; Hofer, E; Binder, BR; Leitinger, N Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca(++)/NFAT.
Blood. 2002; 99(1):199-206 Doi: 10.1182/blood.V99.1.199 [OPEN ACCESS]
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Huber, J; Boechzelt, H; Karten, B; Surboeck, M; Bochkov, VN; Binder, BR; Sattler, W; Leitinger, N Oxidized cholesteryl linoleates stimulate endothelial cells to bind monocytes via the extracellular signal-regulated kinase 1/2 pathway.
Arterioscler Thromb Vasc Biol. 2002; 22(4):581-586 Doi: 10.1161/01.ATV.0000012782.59850.41 [OPEN ACCESS]
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Waldhoer, M; Kledal, TN; Farrell, H; Schwartz, TW Murine cytomegalovirus (CMV) M33 and human CMV US28 receptors exhibit similar constitutive signaling activities.
J Virol. 2002; 76(16):8161-8168 Doi: 10.1128/JVI.76.16.8161-8168.2002 [OPEN ACCESS]
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