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Publikationen

Suchbegriffe: INTERLEUKIN-6, . Treffer: 148

2025

Hoffmann, SW; Schierbauer, J; Zimmermann, P; Voit, T; Grothoff, A; Wachsmuth, N; Rössler, A; Niedrist, T; Lackner, HK; Moser, O Associations Between Clinical Inflammatory Risk Markers, Body Composition, Heart Rate Variability, and Accelerometer-Assessed Physical Activity in University Students with Overweight and Obesity.
Sensors (Basel). 2025; 25(5): Doi: 10.3390/s25051510 [OPEN ACCESS]
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Tomelleri, A; Bond, M; Marvisi, C; Campochiaro, C; Farina, N; Venerandi, B; Matucci-Cerinic, M; Salvarani, C; Dejaco, C; Dagna, L Secukinumab is effective and safe for patients with giant cell arteritis after tocilizumab failure.
Rheumatology (Oxford). 2025; Doi: 10.1093/rheumatology/keaf250
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Weiser-Fuchs, MT; Jantscher, A; Tischler, S; Osto, E; Balayan, L; Scharnagl, H; Jäger, G; Amtmann, B; Kulovic-Sissawo, A; Puster, S; Fluhr, H; Obermayer-Pietsch, B; Stern, C; Hiden, U; Jantscher-Krenn, E Pregnancy shifts endothelial progenitor cell morphology and function: Role of metabolism, pro-inflammatory cytokines and fetal sex.
J Physiol. 2025; Doi: 10.1113/JP288038
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Wissel, S; Scharnagl, H; Kleber, ME; Delgado, G; Moissl, A; Krämer, B; März, W Inflammation, Lp(a) and cardiovascular mortality: results from the LURIC study
CLIN RES CARDIOL. 2025; Doi: 10.1007/s00392-025-02609-4
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2024

Berger, M; März, W; Niessner, A; Delgado, G; Kleber, M; Scharnagl, H; Marx, N; Schuett, K IL-6 and hsCRP predict cardiovascular mortality in patients with heart failure with preserved ejection fraction.
ESC Heart Fail. 2024; Doi: 10.1002/ehf2.14959 [OPEN ACCESS]
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Eichberger, J; Resch, E; Resch, B Reliability of IL-6 Alone and in Combination for Diagnosis of Late Onset Sepsis: A Systematic Review.
Children (Basel). 2024; 11(4): 486 Doi: 10.3390/children11040486 [OPEN ACCESS]
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Hoffmann, SW; Schierbauer, J; Zimmermann, P; Voit, T; Grothoff, A; Wachsmuth, NB; Rössler, A; Niedrist, T; Lackner, HK; Moser, O Effects of Interrupting Prolonged Sitting with Light-Intensity Physical Activity on Inflammatory and Cardiometabolic Risk Markers in Young Adults with Overweight and Obesity: Secondary Outcome Analyses of the SED-ACT Randomized Controlled Crossover Trial.
Biomolecules. 2024; 14(8): Doi: 10.3390/biom14081029 [OPEN ACCESS]
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Klobučar, I; Habisch, H; Klobučar, L; Trbušić, M; Pregartner, G; Berghold, A; Kostner, GM; Scharnagl, H; Madl, T; Frank, S; Degoricija, V Sex-Related Differences in the Associations between Adiponectin and Serum Lipoproteins in Healthy Subjects and Patients with Metabolic Syndrome.
Biomedicines. 2024; 12(9): Doi: 10.3390/biomedicines12091972 [OPEN ACCESS]
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Kreis, L; Dejaco, C; Schmidt, WA; Németh, R; Venhoff, N; Schäfer, VS The Meteoritics Trial: efficacy of methotrexate after remission-induction with tocilizumab and glucocorticoids in giant cell arteritis-study protocol for a randomized, double-blind, placebo-controlled, parallel-group phase II study.
Trials. 2024; 25(1): 56 Doi: 10.1186/s13063-024-07905-4 [OPEN ACCESS]
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Rajabi, A; Akbar, Nezhad, Gharehlo, A; Madadizadeh, E; Basereh, A; Khoramipoor, K; Pirani, H; Khoramipour, K; Moser, O; Khoramipour, K The effect of 12 weeks of aerobic exercise training with or without saffron supplementation on diabetes-specific markers and inflammation in women with type 2 diabetes: A randomized double-blind placebo-controlled trial.
Eur J Sport Sci. 2024; Doi: 10.1002/ejsc.12125 [OPEN ACCESS]
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Zach, DK; Schwegel, N; Santner, V; Winkelbauer, L; Hoeller, V; Kolesnik, E; Gollmer, J; Seggewiss, H; Batzner, A; Perl, S; Wallner, M; Reiter, U; Rainer, PP; Zirlik, A; Ablasser, K; Verheyen, N Low-grade systemic inflammation and left ventricular dysfunction in hypertensive compared to non-hypertensive hypertrophic cardiomyopathy.
Int J Cardiol. 2024; 399:131661 Doi: 10.1016/j.ijcard.2023.131661
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2023

Alhamdan, F; Greulich, T; Daviaud, C; Marsh, LM; Pedersen, F; Thölken, C; Pfefferle, PI; Bahmer, T; Potaczek, DP; Tost, J; Garn, H Identification of extracellular vesicle microRNA signatures specifically linked to inflammatory and metabolic mechanisms in obesity-associated low type-2 asthma.
Allergy. 2023; 78(11):2944-2958 Doi: 10.1111/all.15824
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Benedikt, M; Mangge, H; Aziz, F; Curcic, P; Pailer, S; Herrmann, M; Kolesnik, E; Tripolt, NJ; Pferschy, PN; Wallner, M; Zirlik, A; Sourij, H; von, Lewinski, D Impact of the SGLT2-inhibitor empagliflozin on inflammatory biomarkers after acute myocardial infarction - a post-hoc analysis of the EMMY trial.
Cardiovasc Diabetol. 2023; 22(1): 166 Doi: 10.1186/s12933-023-01904-6 [OPEN ACCESS]
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Pecqueux, M; Brückner, F; Bogner, A; Oehme, F; Hau, HM; von, Bechtolsheim, F; Held, HC; Baenke, F; Distler, M; Riediger, C; Weitz, J; Kahlert, C Interleukin-8 is superior to CRP for the prediction of severe complications in a prospective cohort of patients undergoing major liver resection.
Langenbecks Arch Surg. 2023; 408(1): 377 Doi: 10.1007/s00423-023-03041-w [OPEN ACCESS]
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Pototschnig, I; Feiler, U; Diwoky, C; Vesely, PW; Rauchenwald, T; Paar, M; Bakiri, L; Pajed, L; Hofer, P; Kashofer, K; Sukhbaatar, N; Schoiswohl, G; Weichhart, T; Hoefler, G; Bock, C; Pichler, M; Wagner, EF; Zechner, R; Schweiger, M Interleukin-6 initiates muscle- and adipose tissue wasting in a novel C57BL/6 model of cancer-associated cachexia.
J Cachexia Sarcopenia Muscle. 2023; 14(1):93-107 Doi: 10.1002/jcsm.13109 [OPEN ACCESS]
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Thompson-Peach, CAL; Foßelteder, J; Reinisch, A; Thomas, D Thrombopoietin-independent Megakaryocyte Differentiation of Hematopoietic Progenitor Cells from Patients with Myeloproliferative Neoplasms.
BIO-PROTOCOL. 2023; 13(2): e4592 Doi: 10.21769/BioProtoc.4592 [OPEN ACCESS]
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2022

Eichberger, J; Resch, B Reliability of Interleukin-6 Alone and in Combination for Diagnosis of Early Onset Neonatal Sepsis: Systematic Review.
Front Pediatr. 2022; 10: 840778 Doi: 10.3389/fped.2022.840778 [OPEN ACCESS]
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Eichberger, J; Resch, E; Resch, B Diagnosis of Neonatal Sepsis: The Role of Inflammatory Markers.
Front Pediatr. 2022; 10: 840288 Doi: 10.3389/fped.2022.840288 [OPEN ACCESS]
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Jarius, S; Pache, F; Körtvelyessy, P; Jelčić, I; Stettner, M; Franciotta, D; Keller, E; Neumann, B; Ringelstein, M; Senel, M; Regeniter, A; Kalantzis, R; Willms, JF; Berthele, A; Busch, M; Capobianco, M; Eisele, A; Reichen, I; Dersch, R; Rauer, S; Sandner, K; Ayzenberg, I; Gross, CC; Hegen, H; Khalil, M; Kleiter, I; Lenhard, T; Haas, J; Aktas, O; Angstwurm, K; Kleinschnitz, C; Lewerenz, J; Tumani, H; Paul, F; Stangel, M; Ruprecht, K; Wildemann, B, , ; in, cooperation, with, the, German, Society, for, Cerebrospinal, Fluid, Diagnostics, and, Clinical, Neurochemistry Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients.
J Neuroinflammation. 2022; 19(1): 19 Doi: 10.1186/s12974-021-02339-0 [OPEN ACCESS]
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Kastrati, K; Aletaha, D; Burmester, GR; Chwala, E; Dejaco, C; Dougados, M; McInnes, IB; Ravelli, A; Sattar, N; Stamm, TA; Takeuchi, T; Trauner, M; van der Heijde, D; Voshaar, MJH; Winthrop, K; Smolen, JS; Kerschbaumer, A A systematic literature review informing the consensus statement on efficacy and safety of pharmacological treatment with interleukin-6 pathway inhibition with biological DMARDs in immune-mediated inflammatory diseases
RMD OPEN. 2022; 8(2): e002359 Doi: 10.1136/rmdopen-2022-002359 [OPEN ACCESS]
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Matzer, I; Voglhuber, J; Kiessling, M; Djalinac, N; Trummer-Herbst, V; Mabotuwana, N; Rech, L; Holzer, M; Sossalla, S; Rainer, PP; Zirlik, A; Ljubojevic-Holzer, S β-Adrenergic Receptor Stimulation Maintains NCX-CaMKII Axis and Prevents Overactivation of IL6R-Signaling in Cardiomyocytes upon Increased Workload.
Biomedicines. 2022; 10(7): Doi: 10.3390/biomedicines10071648 [OPEN ACCESS]
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Michaelis, S; Zelzer, S; Schnedl, WJ; Baranyi, A; Meinitzer, A; Enko, D Assessment of tryptophan and kynurenine as prognostic markers in patients with SARS-CoV-2.
Clin Chim Acta. 2022; 525:29-33 Doi: 10.1016/j.cca.2021.12.005 [OPEN ACCESS]
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Peikert, A; König, S; Suchanek, D; Rofa, K; Schäfer, I; Dimanski, D; Karnbrock, L; Bulatova, K; Engelmann, J; Hoppe, N; Wadle, C; Heidt, T; Albrecht, P; von, Garlen, S; Härdtner, C; Hilgendorf, I; Wolf, D; von, Zur, Mühlen, C; Bode, C; Zirlik, A; Duerschmied, D; Merz, J; Stachon, P P2X₄ deficiency reduces atherosclerosis and plaque inflammation in mice.
Sci Rep. 2022; 12(1):2801 Doi: 10.1038/s41598-022-06706-6 [OPEN ACCESS]
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Sauer, A; Seeliger, B; Jandl, K; Erfinanda, L; Wilhelm, J; Alexopoulos, I; Baal, N; Birnhuber, A; David, S; Welte, T; Barreto, G; Gaertner, U; Kwapiszewska, G; Seeger, W; Kuebler, WM; Schaefer, L; Wygrecka, M, , members, of, the, CAPNETZ, Study, Group Circulating hyaluronic acid signature in CAP and ARDS - the role of pneumolysin in hyaluronic acid shedding.
Matrix Biol. 2022; 114: 67-83. Doi: 10.1016/j.matbio.2022.11.003
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Syme, TE; Grill, M; Hayashida, E; Viengkhou, B; Campbell, IL; Hofer, MJ Strawberry notch homolog 2 regulates the response to interleukin-6 in the central nervous system.
J Neuroinflammation. 2022; 19(1): 126 Doi: 10.1186/s12974-022-02475-1 [OPEN ACCESS]
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2021

Flynn, CM; Kespohl, B; Daunke, T; Garbers, Y; Düsterhöft, S; Rose-John, S; Haybaeck, J; Lokau, J; Aparicio-Siegmund, S; Garbers, C Interleukin-6 controls recycling and degradation, but not internalization of its receptors.
J Biol Chem. 2021; 100434-100434. Doi: 10.1016/j.jbc.2021.100434 [OPEN ACCESS]
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Georgieva, E; Leber, SL; Wex, C; Garbers, C Perturbation of the Actin Cytoskeleton in Human Hepatoma Cells Influences Interleukin-6 (IL-6) Signaling, but Not Soluble IL-6 Receptor Generation or NF-κB Activation.
Int J Mol Sci. 2021; 22(13): 7171 Doi: 10.3390/ijms22137171 [OPEN ACCESS]
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Jud, P; Gressenberger, P; Muster, V; Avian, A; Meinitzer, A; Strohmaier, H; Sourij, H; Raggam, RB; Stradner, MH; Demel, U; Kessler, HH; Eller, K; Brodmann, M Evaluation of Endothelial Dysfunction and Inflammatory Vasculopathy After SARS-CoV-2 Infection-A Cross-Sectional Study.
Front Cardiovasc Med. 2021; 8: 750887 Doi: 10.3389/fcvm.2021.750887 [OPEN ACCESS]
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Mangge, H; Herrmann, M; Meinitzer, A; Pailer, S; Curcic, P; Sloup, Z; Holter, M; Prüller, F Increased Kynurenine Indicates a Fatal Course of COVID-19.
Antioxidants (Basel). 2021; 10(12): Doi: 10.3390/antiox10121960 [OPEN ACCESS]
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Munker, D; Osterman, A; Stubbe, H; Muenchhoff, M; Veit, T; Weinberger, T; Barnikel, M; Mumm, JN; Milger, K; Khatamzas, E; Klauss, S; Scherer, C; Hellmuth, JC; Giessen-Jung, C; Zoller, M; Herold, T; Stecher, S; de, Toni, EN; Schulz, C; Kneidinger, N; Keppler, OT; Behr, J; Mayerle, J; Munker, S Dynamics of SARS-CoV-2 shedding in the respiratory tract depends on the severity of disease in COVID-19 patients.
Eur Respir J. 2021; 58(1): Doi: 10.1183/13993003.02724-2020 [OPEN ACCESS]
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Valverde, I; Singh, Y; Sanchez-de-Toledo, J; Theocharis, P; Chikermane, A; Di Filippo, S; Kuciñska, B; Mannarino, S; Tamariz-Martel, A; Gutierrez-Larraya, F; Soda, G; Vandekerckhove, K; Gonzalez-Barlatay, F; McMahon, CJ; Marcora, S; Napoleone, CP; Duong, P; Tuo, G; Deri, A; Nepali, G; Ilina, M; Ciliberti, P; Miller, O; AEPC COVID-19 Rapid Response Team* Acute Cardiovascular Manifestations in 286 Children With Multisystem Inflammatory Syndrome Associated With COVID-19 Infection in Europe.
Circulation. 2021; 143(1):21-32 Doi: 10.1161/CIRCULATIONAHA.120.050065
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Zwirner, J; Bohnert, S; Franke, H; Garland, J; Hammer, N; Möbius, D; Tse, R; Ondruschka, B Assessing Protein Biomarkers to Detect Lethal Acute Traumatic Brain Injuries in Cerebrospinal Fluid.
Biomolecules. 2021; 11(11): Doi: 10.3390/biom11111577 [OPEN ACCESS]
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2020

Cubero, FJ; Mohamed, MR; Woitok, MM; Zhao, G; Hatting, M; Nevzorova, YA; Chen, C; Haybaeck, J; de Bruin, A; Avila, MA; Boekschoten, MV; Davis, RJ; Trautwein, C Loss of c-Jun N-terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma.
Hepatol Commun. 2020; 4(6): 834-851. Doi: 10.1002/hep4.1495 [OPEN ACCESS]
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Enko, D; Zelzer, S; Wenninger, J; Holasek, S; Schnedl, WJ; Baranyi, A; Herrmann, M; Meinitzer, A Interleukin-6 is associated with tryptophan metabolism and signs of depression in individuals with carbohydrate malabsorption.
EXCLI J. 2020; 19(23):1414-1422 Doi: 10.17179/excli2020-2940 [OPEN ACCESS]
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Klim, SM; Amerstorfer, F; Glehr, G; Hauer, G; Smolle, MA; Leitner, L; Leithner, A; Glehr, M Combined serum biomarker analysis shows no benefit in the diagnosis of periprosthetic joint infection.
Int Orthop. 2020; Doi: 10.1007/s00264-020-04731-6 [OPEN ACCESS]
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Lokau, J; Kleinegger, F; Garbers, Y; Waetzig, GH; Grötzinger, J; Rose-John, S; Haybaeck, J; Garbers, C Tocilizumab does not block interleukin-6 (IL-6) signaling in murine cells.
PLoS One. 2020; 15(5): e0232612-e0232612. Doi: 10.1371/journal.pone.0232612 [OPEN ACCESS]
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Mangge, H; Herrmann, M; Almer, G; Zelzer, S; Moeller, R; Horejsi, R; Renner, W Telomere shortening associates with elevated insulin and nuchal fat accumulation.
Sci Rep. 2020; 10(1):6863-6863 Doi: 10.1038/s41598-020-63916-6 [OPEN ACCESS]
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Mörwald, K; Aigner, E; Bergsten, P; Brunner, SM; Forslund, A; Kullberg, J; Ahlström, H; Manell, H; Roomp, K; Schütz, S; Zsoldos, F; Renner, W; Furthner, D; Maruszczak, K; Zandanell, S; Weghuber, D; Mangge, H Serum Ferritin Correlates With Liver Fat in Male Adolescents With Obesity.
Front Endocrinol (Lausanne). 2020; 11: 340-340. Doi: 10.3389/fendo.2020.00340 [OPEN ACCESS]
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Obermüller, B; Frisina, N; Meischel, M; Singer, G; Stanzl-Tschegg, S; Lichtenegger, H; Kolb, D; Klymiuk, I; Till, H; Castellani, C Examination of intestinal ultrastructure, bowel wall apoptosis and tight junctions in the early phase of sepsis.
Sci Rep. 2020; 10(1): 11507-11507. Doi: 10.1038/s41598-020-68109-9 [OPEN ACCESS]
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Pusceddu, I; Herrmann, W; Kleber, ME; Scharnagl, H; Hoffmann, MM; Winklhofer-Roob, BM; März, W; Herrmann, M Subclinical inflammation, telomere shortening, homocysteine, vitamin B6, and mortality: the Ludwigshafen Risk and Cardiovascular Health Study.
Eur J Nutr. 2020; 59(4):1399-1411 Doi: 10.1007/s00394-019-01993-8 [OPEN ACCESS]
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Reiter, A; Bengesser, SA; Hauschild, AC; Birkl-Töglhofer, AM; Fellendorf, FT; Platzer, M; Färber, T; Seidl, M; Mendel, LM; Unterweger, R; Lenger, M; Mörkl, S; Dalkner, N; Birner, A; Queissner, R; Hamm, C; Maget, A; Pilz, R; Kohlhammer-Dohr, A; Wagner-Skacel, J; Kreuzer, K; Schöggl, H; Amberger-Otti, D; Lahousen, T; Leitner-Afschar, B; Haybäck, J; Kapfhammer, HP; Reininghaus, E Interleukin-6 Gene Expression Changes after a 4-Week Intake of a Multispecies Probiotic in Major Depressive Disorder-Preliminary Results of the PROVIT Study.
Nutrients. 2020; 12(9): Doi: 10.3390/nu12092575 [OPEN ACCESS]
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Ritsch, A; Duerr, A; Kahler, P; Hunjadi, M; Stojakovic, T; Silbernagel, G; Scharnagl, H; Kleber, ME; März, W Cholesterol Efflux Capacity and Cardiovascular Disease: The Ludwigshafen Risk and Cardiovascular Health (LURIC) Study.
Biomedicines. 2020; 8(11): Doi: 10.3390/biomedicines8110524 [OPEN ACCESS]
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Wolfsberger, CH; Bruckner, M; Baik-Schneditz, N; Schwaberger, B; Mileder, LP; Avian, A; Urlesberger, B; Pichler, G Fetal Inflammatory Response Syndrome and Cerebral Oxygenation During Immediate Postnatal Transition in Preterm Neonates.
Front Pediatr. 2020; 8:401 Doi: 10.3389/fped.2020.00401 [OPEN ACCESS]
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2019

Friesecke, S; Träger, K; Schittek, GA; Molnar, Z; Bach, F; Kogelmann, K; Bogdanski, R; Weyland, A; Nierhaus, A; Nestler, F; Olboeter, D; Tomescu, D; Jacob, D; Haake, H; Grigoryev, E; Nitsch, M; Baumann, A; Quintel, M; Schott, M; Kielstein, JT; Meier-Hellmann, A; Born, F; Schumacher, U; Singer, M; Kellum, J; Brunkhorst, FM International registry on the use of the CytoSorb® adsorber in ICU patients : Study protocol and preliminary results.
Med Klin Intensivmed Notfmed. 2019; 114(8):699-707 Doi: 10.1007/s00063-017-0342-5 [OPEN ACCESS]
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Kröpfl, JM; Tschakert, G; Stelzer, I; Pekovits, K; Zelzer, S; Dohr, G; Holasek, S; Stojakovic, T; Scharnagl, H; Spengler, CM; Hofmann, P Acute Exercise-Induced Circulating Haematopoietic Stem and Progenitor Cells in Cardiac Patients - A Case Series.
Heart Lung Circ. 2019; 28(4):e54-e58 Doi: 10.1016/j.hlc.2018.05.095
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Lokau, J; Schoeder, V; Haybaeck, J; Garbers, C Jak-Stat Signaling Induced by Interleukin-6 Family Cytokines in Hepatocellular Carcinoma.
Cancers (Basel). 2019; 11(11): Doi: 10.3390/cancers11111704 [OPEN ACCESS]
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Mangge, H; Almer, G Immune-Mediated Inflammation in Vulnerable Atherosclerotic Plaques.
Molecules. 2019; 24(17): Doi: 10.3390/molecules24173072 [OPEN ACCESS]
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Ondruschka, B; Woydt, L; Bernhard, M; Franke, H; Kirsten, H; Löffler, S; Pohlers, D; Hammer, N; Dreßler, J Post-mortem in situ stability of serum markers of cerebral damage and acute phase response.
Int J Legal Med. 2019; 133(3):871-881 Doi: 10.1007/s00414-018-1925-2
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Prenissl, N; Lokau, J; Rose-John, S; Haybaeck, J; Garbers, C Therapeutic blockade of the interleukin-6 receptor (IL-6R) allows sIL-6R generation by proteolytic cleavage.
Cytokine. 2019; 114(4):1-5 Doi: 10.1016/j.cyto.2018.11.023 [OPEN ACCESS]
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Pusceddu, I; Herrmann, W; Kleber, ME; Scharnagl, H; März, W; Herrmann, M Telomere length, vitamin B12 and mortality in persons undergoing coronary angiography: the Ludwigshafen risk and cardiovascular health study.
Aging (Albany NY). 2019; 11(17): 7083-7097. Doi: 10.18632/aging.102238 [OPEN ACCESS]
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