Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Suchbegriffe: TRIGLYCERIDES - METABOLISM, . Treffer: 86

2018

Segerer, G; Engelmann, D; Kaestner, A; Trötzmüller, M; Köfeler, H; Stigloher, C; Thiele, C; Jeanclos, E; Gohla, A A phosphoglycolate phosphatase/AUM-dependent link between triacylglycerol turnover and epidermal growth factor signaling.
Biochim Biophys Acta. 2018; 1863(6):584-594
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2017

Grond, S; Radner, FPW; Eichmann, TO; Kolb, D; Grabner, GF; Wolinski, H; Gruber, R; Hofer, P; Heier, C; Schauer, S; Rülicke, T; Hoefler, G; Schmuth, M; Elias, PM; Lass, A; Zechner, R; Haemmerle, G Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation.
J Invest Dermatol. 2017; 137(2):403-413 [OPEN ACCESS]
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Lindquist, C; Bjørndal, B; Rossmann, CR; Tusubira, D; Svardal, A; Røsland, GV; Tronstad, KJ; Hallström, S; Berge, RK Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in rats.
J Lipid Res. 2017; 58(7):1362-1373 [OPEN ACCESS]
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Zechner, R; Madeo, F; Kratky, D Cytosolic lipolysis and lipophagy: two sides of the same coin.
Nat Rev Mol Cell Biol. 2017; 18(11):671-684
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2016

Bartuzi, P; Billadeau, DD; Favier, R; Rong, S; Dekker, D; Fedoseienko, A; Fieten, H; Wijers, M; Levels, JH; Huijkman, N; Kloosterhuis, N; van der Molen, H; Brufau, G; Groen, AK; Elliott, AM; Kuivenhoven, JA; Plecko, B; Grangl, G; McGaughran, J; Horton, JD; Burstein, E; Hofker, MH; van de Sluis, B CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.
Nat Commun. 2016; 7(5):10961-10961 [OPEN ACCESS]
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Dichlberger, A; Schlager, S; Kovanen, PT; Schneider, WJ Lipid droplets in activated mast cells - a significant source of triglyceride-derived arachidonic acid for eicosanoid production.
Eur J Pharmacol. 2016; 785(2):59-69
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Fengler, VH; Macheiner, T; Kessler, SM; Czepukojc, B; Gemperlein, K; Müller, R; Kiemer, AK; Magnes, C; Haybaeck, J; Lackner, C; Sargsyan, K Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease.
PLoS One. 2016; 11(5):e0155163-e0155163 [OPEN ACCESS]
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Grumet, L; Eichmann, TO; Taschler, U; Zierler, KA; Leopold, C; Moustafa, T; Radovic, B; Romauch, M; Yan, C; Du, H; Haemmerle, G; Zechner, R; Fickert, P; Kratky, D; Zimmermann, R; Lass, A Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover.
J Biol Chem. 2016; 291(34):17977-17987 [OPEN ACCESS]
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Klein, I; Klug, L; Schmidt, C; Zandl, M; Korber, M; Daum, G; Athenstaedt, K Regulation of the yeast triacylglycerol lipases Tgl4p and Tgl5p by the presence/absence of nonpolar lipids.
Mol Biol Cell. 2016; 27(13):2014-2024 [OPEN ACCESS]
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Radović, B; Vujić, N; Leopold, C; Schlager, S; Goeritzer, M; Patankar, JV; Korbelius, M; Kolb, D; Reindl, J; Wegscheider, M; Tomin, T; Birner-Gruenberger, R; Schittmayer, M; Groschner, L; Magnes, C; Diwoky, C; Frank, S; Steyrer, E; Du, H; Graier, WF; Madl, T; Kratky, D Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice.
Diabetologia. 2016; 59(8):1743-1752 [OPEN ACCESS]
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Sachdev, V; Leopold, C; Bauer, R; Patankar, JV; Iqbal, J; Obrowsky, S; Boverhof, R; Doktorova, M; Scheicher, B; Goeritzer, M; Kolb, D; Turnbull, AV; Zimmer, A; Hoefler, G; Hussain, MM; Groen, AK; Kratky, D Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.
Biochim Biophys Acta. 2016; 1861(9 Pt A):1132-1141 [OPEN ACCESS]
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2015

Bitter, A; Rümmele, P; Klein, K; Kandel, BA; Rieger, JK; Nüssler, AK; Zanger, UM; Trauner, M; Schwab, M; Burk, O Pregnane X receptor activation and silencing promote steatosis of human hepatic cells by distinct lipogenic mechanisms.
Arch Toxicol. 2015; 89(11):2089-2103
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Boeszoermenyi, A; Nagy, HM; Arthanari, H; Pillip, CJ; Lindermuth, H; Luna, RE; Wagner, G; Zechner, R; Zangger, K; Oberer, M Structure of a CGI-58 motif provides the molecular basis of lipid droplet anchoring.
J Biol Chem. 2015; 290(44):26361-26372 [OPEN ACCESS]
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Eichmann, TO; Grumet, L; Taschler, U; Hartler, J; Heier, C; Woblistin, A; Pajed, L; Kollroser, M; Rechberger, G; Thallinger, GG; Zechner, R; Haemmerle, G; Zimmermann, R; Lass, A ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6.
J Lipid Res. 2015; 56(10):1972-1984 [OPEN ACCESS]
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Goeritzer, M; Vujic, N; Schlager, S; Chandak, PG; Korbelius, M; Gottschalk, B; Leopold, C; Obrowsky, S; Rainer, S; Doddapattar, P; Aflaki, E; Wegscheider, M; Sachdev, V; Graier, WF; Kolb, D; Radovic, B; Kratky, D Active autophagy but not lipophagy in macrophages with defective lipolysis.
Biochim Biophys Acta. 2015; 1851(10):1304-1316 [OPEN ACCESS]
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Heier, C; Radner, FP; Moustafa, T; Schreiber, R; Grond, S; Eichmann, TO; Schweiger, M; Schmidt, A; Cerk, IK; Oberer, M; Theussl, HC; Wojciechowski, J; Penninger, JM; Zimmermann, R; Zechner, R G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis.
J Biol Chem. 2015; 290(43):26141-26150 [OPEN ACCESS]
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Hofer, P; Boeszoermenyi, A; Jaeger, D; Feiler, U; Arthanari, H; Mayer, N; Zehender, F; Rechberger, G; Oberer, M; Zimmermann, R; Lass, A; Haemmerle, G; Breinbauer, R; Zechner, R; Preiss-Landl, K Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling.
J Biol Chem. 2015; 290(30):18438-18453 [OPEN ACCESS]
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Taschler, U; Schreiber, R; Chitraju, C; Grabner, GF; Romauch, M; Wolinski, H; Haemmerle, G; Breinbauer, R; Zechner, R; Lass, A; Zimmermann, R Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells.
Biochim Biophys Acta. 2015; 1851(7):937-945 [OPEN ACCESS]
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2014

Brahma, MK; Adam, RC; Pollak, NM; Jaeger, D; Zierler, KA; Pöcher, N; Schreiber, R; Romauch, M; Moustafa, T; Eder, S; Ruelicke, T; Preiss-Landl, K; Lass, A; Zechner, R; Haemmerle, G Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis.
J Lipid Res. 2014; 55(11):2229-2241 [OPEN ACCESS]
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Dichlberger, A; Schlager, S; Maaninka, K; Schneider, WJ; Kovanen, PT Adipose triglyceride lipase regulates eicosanoid production in activated human mast cells.
J Lipid Res. 2014; 55(12):2471-2478 [OPEN ACCESS]
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Goeritzer, M; Schlager, S; Radovic, B; Madreiter, CT; Rainer, S; Thomas, G; Lord, CC; Sacks, J; Brown, AL; Vujic, N; Obrowsky, S; Sachdev, V; Kolb, D; Chandak, PG; Graier, WF; Sattler, W; Brown, JM; Kratky, D Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis.
J Lipid Res. 2014; 55(12):2562-2575 [OPEN ACCESS]
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Nagy, HM; Paar, M; Heier, C; Moustafa, T; Hofer, P; Haemmerle, G; Lass, A; Zechner, R; Oberer, M; Zimmermann, R Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.
Biochim Biophys Acta. 2014; 1841(4):588-594 [OPEN ACCESS]
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Schrammel, A; Mussbacher, M; Wölkart, G; Stessel, H; Pail, K; Winkler, S; Schweiger, M; Haemmerle, G; Al Zoughbi, W; Höfler, G; Lametschwandtner, A; Zechner, R; Mayer, B Endothelial dysfunction in adipose triglyceride lipase deficiency.
Biochim Biophys Acta. 2014; 1841(6):906-917 [OPEN ACCESS]
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Schweiger, M; Eichmann, TO; Taschler, U; Zimmermann, R; Zechner, R; Lass, A Measurement of lipolysis.
Methods Enzymol. 2014; 538(7):171-193 [OPEN ACCESS]
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2013

Fuchs, C; Claudel, T; Trauner, M Bile acid-mediated control of liver triglycerides.
Semin Liver Dis. 2013; 33(4):330-342
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Ploier, B; Scharwey, M; Koch, B; Schmidt, C; Schatte, J; Rechberger, G; Kollroser, M; Hermetter, A; Daum, G Screening for hydrolytic enzymes reveals Ayr1p as a novel triacylglycerol lipase in Saccharomyces cerevisiae.
J Biol Chem. 2013; 288(50):36061-36072 [OPEN ACCESS]
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Pollak, NM; Schweiger, M; Jaeger, D; Kolb, D; Kumari, M; Schreiber, R; Kolleritsch, S; Markolin, P; Grabner, GF; Heier, C; Zierler, KA; Rülicke, T; Zimmermann, R; Lass, A; Zechner, R; Haemmerle, G Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier.
J Lipid Res. 2013; 54(4):1092-1102 [OPEN ACCESS]
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Radulovic, M; Knittelfelder, O; Cristobal-Sarramian, A; Kolb, D; Wolinski, H; Kohlwein, SD The emergence of lipid droplets in yeast: current status and experimental approaches.
Curr Genet. 2013; 59(4):231-242 [OPEN ACCESS]
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Zierler, KA; Jaeger, D; Pollak, NM; Eder, S; Rechberger, GN; Radner, FP; Woelkart, G; Kolb, D; Schmidt, A; Kumari, M; Preiss-Landl, K; Pieske, B; Mayer, B; Zimmermann, R; Lass, A; Zechner, R; Haemmerle, G Functional cardiac lipolysis in mice critically depends on comparative gene identification-58.
J Biol Chem. 2013; 288(14):9892-9904 [OPEN ACCESS]
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2012

Aflaki, E; Doddapattar, P; Radovic, B; Povoden, S; Kolb, D; Vujic, N; Wegscheider, M; Koefeler, H; Hornemann, T; Graier, WF; Malli, R; Madeo, F; Kratky, D C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages.
Cell Death Dis. 2012; 3(6):e280-e280 [OPEN ACCESS]
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Chitraju, C; Trotzmuller, M; Hartler, J; Wolinski, H; Thallinger, GG; Lass, A; Zechner, R; Zimmermann, R; Kofeler, HC; Spener, F; Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress.
J Lipid Res. 2012; 53(10):2141-2152 [OPEN ACCESS]
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Fuchs, CD; Claudel, T; Kumari, P; Haemmerle, G; Pollheimer, MJ; Stojakovic, T; Scharnagl, H; Halilbasic, E; Gumhold, J; Silbert, D; Koefeler, H; Trauner, M Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice.
Hepatology. 2012; 56(1):270-280 [OPEN ACCESS]
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Jaffer, I; Riederer, M; Shah, P; Peters, P; Quehenberger, F; Wood, A; Scharnagl, H; März, W; Kostner, KM; Kostner, GM Expression of fat mobilizing genes in human epicardial adipose tissue.
Atherosclerosis. 2012; 220(1): 122-127.
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Morak, M; Schmidinger, H; Riesenhuber, G; Rechberger, GN; Kollroser, M; Haemmerle, G; Zechner, R; Kronenberg, F; Hermetter, A Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) deficiencies affect expression of lipolytic activities in mouse adipose tissues.
Mol Cell Proteomics. 2012; 11(12):1777-1789 [OPEN ACCESS]
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Moustafa, T; Fickert, P; Magnes, C; Guelly, C; Thueringer, A; Frank, S; Kratky, D; Sattler, W; Reicher, H; Sinner, F; Gumhold, J; Silbert, D; Fauler, G; Höfler, G; Lass, A; Zechner, R; Trauner, M Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Gastroenterology. 2012; 142(1):140-151
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Obrowsky, S; Chandak, PG; Patankar, JV; Pfeifer, T; Povoden, S; Schreiber, R; Haemmerle, G; Levak-Frank, S; Kratky, D Cholesteryl ester accumulation and accelerated cholesterol absorption in intestine-specific hormone sensitive lipase-null mice.
Biochim Biophys Acta. 2012; 1821(11):1406-1414 [OPEN ACCESS]
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Patankar, JV; Obrowsky, S; Doddapattar, P; Hoefler, G; Battle, M; Levak-Frank, S; Kratky, D Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis.
J Hepatol. 2012; 57(5):1061-1068 [OPEN ACCESS]
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Petritsch, B; Köstler, H; Machann, W; Horn, M; Weng, AM; Goltz, JP; Hahn, D; Niemann, M; Weidemann, F; Wanner, C; Beer, M Non-invasive determination of myocardial lipid content in Fabry disease by 1H-MR spectroscopy.
Rofo. 2012; 184(11):1020-1025
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Quiroga, AD; Li, L; Trötzmüller, M; Nelson, R; Proctor, SD; Köfeler, H; Lehner, R Deficiency of carboxylesterase 1/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia.
Hepatology. 2012; 56(6):2188-2198 [OPEN ACCESS]
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Riederer, M; Köfeler, H; Lechleitner, M; Tritscher, M; Frank, S Impact of endothelial lipase on cellular lipid composition.
Biochim Biophys Acta. 2012; 1821(7):1003-1011 [OPEN ACCESS]
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Silbernagel, G; Kovarova, M; Cegan, A; Machann, J; Schick, F; Lehmann, R; Häring, HU; Stefan, N; Schleicher, E; Fritsche, A; Peter, A High hepatic SCD1 activity is associated with low liver fat content in healthy subjects under a lipogenic diet.
J Clin Endocrinol Metab. 2012; 97(12):E2288-E2292 [OPEN ACCESS]
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Tamilarasan, KP; Temmel, H; Das, SK; Al Zoughbi, W; Schauer, S; Vesely, PW; Hoefler, G Skeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity.
Cell Death Dis. 2012; 3(11):e354-e354 [OPEN ACCESS]
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2011

Aflaki, E; Radovic, B; Chandak, PG; Kolb, D; Eisenberg, T; Ring, J; Fertschai, I; Uellen, A; Wolinski, H; Kohlwein, SD; Zechner, R; Levak-Frank, S; Sattler, W; Graier, WF; Malli, R; Madeo, F; Kratky, D Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages.
J Biol Chem. 2011; 286(9): 7418-7428. [OPEN ACCESS]
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Bernini, F; Fisher, R; Freeman, D; Groen, A; Kalopissis, A; Malle, E; Mulder, M; Niemeier, A; Parini, P; Hansen, AT; von Eckardstein, A Report of the 33rd annual conference of the European Lipoprotein Club, Tutzing, 6-9 September 2010.
Atherosclerosis. 2011; 215(1): 249-255.
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Dichlberger, A; Schlager, S; Lappalainen, J; Käkelä, R; Hattula, K; Butcher, SJ; Schneider, WJ; Kovanen, PT Lipid body formation during maturation of human mast cells.
J Lipid Res. 2011; 52(12):2198-2208 [OPEN ACCESS]
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Etschmaier, K; Becker, T; Eichmann, TO; Schweinzer, C; Scholler, M; Tam-Amersdorfer, C; Poeckl, M; Schuligoi, R; Kober, A; Chirackal Manavalan, AP; Rechberger, GN; Streith, IE; Zechner, R; Zimmermann, R; Panzenboeck, U Adipose triglyceride lipase affects triacylglycerol metabolism at brain barriers.
J Neurochem. 2011; 119(5): 1016-1028. [OPEN ACCESS]
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Haemmerle, G; Moustafa, T; Woelkart, G; Büttner, S; Schmidt, A; van de Weijer, T; Hesselink, M; Jaeger, D; Kienesberger, PC; Zierler, K; Schreiber, R; Eichmann, T; Kolb, D; Kotzbeck, P; Schweiger, M; Kumari, M; Eder, S; Schoiswohl, G; Wongsiriroj, N; Pollak, NM; Radner, FP; Preiss-Landl, K; Kolbe, T; Rülicke, T; Pieske, B; Trauner, M; Lass, A; Zimmermann, R; Hoefler, G; Cinti, S; Kershaw, EE; Schrauwen, P; Madeo, F; Mayer, B; Zechner, R ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.
Nat Med. 2011; 17(9):1076-1085 [OPEN ACCESS]
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Horvath, SE; Wagner, A; Steyrer, E; Daum, G Metabolic link between phosphatidylethanolamine and triacylglycerol metabolism in the yeast Saccharomyces cerevisiae.
Biochim Biophys Acta. 2011; 1811(12): 1030-1037. [OPEN ACCESS]
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Sloan, C; Tuinei, J; Nemetz, K; Frandsen, J; Soto, J; Wride, N; Sempokuya, T; Alegria, L; Bugger, H; Abel, ED Central leptin signaling is required to normalize myocardial fatty acid oxidation rates in caloric-restricted ob/ob mice.
Diabetes. 2011; 60(5): 1424-1434. [OPEN ACCESS]
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Wagner, M; Zollner, G; Trauner, M Nuclear receptors in liver disease.
HEPATOLOGY. 2011; 53(3): 1023-1034. [OPEN ACCESS]
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