Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Logo MUG-Forschungsportal

Publikationen

Suchbegriffe: PROTEIN CONFORMATION - , . Treffer: 60

2021

Zhang, Y; Dijkman, PM; Zou, R; Zandl-Lang, M; Sanchez, RM; Eckhardt-Strelau, L; Köfeler, H; Vogel, H; Yuan, S; Kudryashev, M Asymmetric opening of the homopentameric 5-HT3A serotonin receptor in lipid bilayers.
Nat Commun. 2021; 12(1):1074-1074 Doi: 10.1038/s41467-021-21016-7 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2020

Pogenberg, V; Ballesteros-Álvarez, J; Schober, R; Sigvaldadóttir, I; Obarska-Kosinska, A; Milewski, M; Schindl, R; Ögmundsdóttir, MH; Steingrímsson, E; Wilmanns, M Mechanism of conditional partner selectivity in MITF/TFE family transcription factors with a conserved coiled coil stammer motif.
Nucleic Acids Res. 2020; 48(2):934-948 Doi: 10.1093/nar/gkz1104 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Spreitzer, E; Usluer, S; Madl, T Probing Surfaces in Dynamic Protein Interactions.
J Mol Biol. 2020; 432(9):2949-2972 Doi: 10.1016/j.jmb.2020.02.032 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

2019

Del Arco, J; Perona, A; González, L; Fernández-Lucas, J; Gago, F; Sánchez-Murcia, PA Reaction mechanism of nucleoside 2'-deoxyribosyltransferases: free-energy landscape supports an oxocarbenium ion as the reaction intermediate.
Org Biomol Chem. 2019; 17(34):7891-7899 Doi: 10.1039/c9ob01315f [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

2017

Byrgazov, K; Kastner, R; Gorna, M; Hoermann, G; Koenig, M; Lucini, CB; Ulreich, R; Benesch, M; Strenger, V; Lackner, H; Schwinger, W; Sovinz, P; Haas, OA; van den Heuvel-Eibrink, M; Niemeyer, CM; Hantschel, O; Valent, P; Superti-Furga, G; Urban, C; Dworzak, MN; Lion, T NDEL1-PDGFRB fusion gene in a myeloid malignancy with eosinophilia associated with resistance to tyrosine kinase inhibitors.
Leukemia. 2017; 31(1):237-240 Doi: 10.1038/leu.2016.250 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Crespo, N; Sánchez-Murcia, PA; Gago, F; Cejudo-Sanches, J; Galmes, MA; Fernández-Lucas, J; Mancheño, JM 2'-Deoxyribosyltransferase from Leishmania mexicana, an efficient biocatalyst for one-pot, one-step synthesis of nucleosides from poorly soluble purine bases.
Appl Microbiol Biotechnol. 2017; 101(19):7187-7200 Doi: 10.1007/s00253-017-8450-y
Web of Science PubMed FullText FullText_MUG

 

Sánchez-Murcia, PA; Cortés-Cabrera, Á; Gago, F Structural rationale for the cross-resistance of tumor cells bearing the A399V variant of elongation factor eEF1A1 to the structurally unrelated didemnin B, ternatin, nannocystin A and ansatrienin B.
J Comput Aided Mol Des. 2017; 31(10):915-928 Doi: 10.1007/s10822-017-0066-x
Web of Science PubMed FullText FullText_MUG

 

2016

Anvarian, Z; Nojima, H; van Kappel, EC; Madl, T; Spit, M; Viertler, M; Jordens, I; Low, TY; van Scherpenzeel, RC; Kuper, I; Richter, K; Heck, AJ; Boelens, R; Vincent, JP; Rüdiger, SG; Maurice, MM Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network.
Nat Struct Mol Biol. 2016; 23(4):324-332 Doi: 10.1038/nsmb.3191
Web of Science PubMed FullText FullText_MUG

 

Aschauer, P; Rengachari, S; Lichtenegger, J; Schittmayer, M; Das, KM; Mayer, N; Breinbauer, R; Birner-Gruenberger, R; Gruber, CC; Zimmermann, R; Gruber, K; Oberer, M Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p.
Biochim Biophys Acta. 2016; 1861(5):462-470 Doi: 10.1016/j.bbalip.2016.02.005 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Biundo, A; Hromic, A; Pavkov-Keller, T; Gruber, K; Quartinello, F; Haernvall, K; Perz, V; Arrell, MS; Zinn, M; Ribitsch, D; Guebitz, GM Characterization of a poly(butylene adipate-co-terephthalate)- hydrolyzing lipase from Pelosinus fermentans.
Appl Microbiol Biotechnol. 2016; 100(4): 1753-1764. Doi: 10.1007/s00253-015-7031-1 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Hartlmüller, C; Göbl, C; Madl, T Prediction of Protein Structure Using Surface Accessibility Data.
Angew Chem Int Ed Engl. 2016; 55(39):11970-11974 Doi: 10.1002/anie.201604788 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Perz, V; Baumschlager, A; Bleymaier, K; Zitzenbacher, S; Hromic, A; Steinkellner, G; Pairitsch, A; Łyskowski, A; Gruber, K; Sinkel, C; Küper, U; Ribitsch, D; Guebitz, GM Hydrolysis of synthetic polyesters by Clostridium botulinum esterases.
Biotechnol Bioeng. 2016; 113(5): 1024-1034. Doi: 10.1002/bit.25874
Web of Science PubMed FullText FullText_MUG

 

Voith von Voithenberg, L; Sánchez-Rico, C; Kang, HS; Madl, T; Zanier, K; Barth, A; Warner, LR; Sattler, M; Lamb, DC Recognition of the 3' splice site RNA by the U2AF heterodimer involves a dynamic population shift.
Proc Natl Acad Sci U S A. 2016; 113(46):E7169-E7175 Doi: 10.1073/pnas.1605873113 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Weber, J; Bao, H; Hartlmüller, C; Wang, Z; Windhager, A; Janowski, R; Madl, T; Jin, P; Niessing, D Structural basis of nucleic-acid recognition and double-strand unwinding by the essential neuronal protein Pur-alpha.
Elife. 2016; 5(7): Doi: 10.7554/eLife.11297 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Zierer, BK; Rübbelke, M; Tippel, F; Madl, T; Schopf, FH; Rutz, DA; Richter, K; Sattler, M; Buchner, J Importance of cycle timing for the function of the molecular chaperone Hsp90.
Nat Struct Mol Biol. 2016; 23(11):1020-1028 Doi: 10.1038/nsmb.3305 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2015

Benavente, R; Esteban-Torres, M; Kohring, GW; Cortés-Cabrera, Á; Sánchez-Murcia, PA; Gago, F; Acebrón, I; de las Rivas, B; Muñoz, R; Mancheño, JM Enantioselective oxidation of galactitol 1-phosphate by galactitol-1-phosphate 5-dehydrogenase from Escherichia coli.
Acta Crystallogr D Biol Crystallogr. 2015; 71(Pt 7):1540-1554 Doi: 10.1107/S1399004715009281
Web of Science PubMed FullText FullText_MUG

 

Chromikova, V; Mader, A; Hofbauer, S; Göbl, C; Madl, T; Gach, JS; Bauernfried, S; Furtmüller, PG; Forthal, DN; Mach, L; Obinger, C; Kunert, R Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM.
Biochim Biophys Acta. 2015; 1854(10 Pt A):1536-1544 Doi: 10.1016/j.bbapap.2015.02.018 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Gersch, M; Famulla, K; Dahmen, M; Göbl, C; Malik, I; Richter, K; Korotkov, VS; Sass, P; Rübsamen-Schaeff, H; Madl, T; Brötz-Oesterhelt, H; Sieber, SA AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control.
Nat Commun. 2015; 6(2):6320-6320 Doi: 10.1038/ncomms7320 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

2014

Basmanav, FB; Oprisoreanu, AM; Pasternack, SM; Thiele, H; Fritz, G; Wenzel, J; Größer, L; Wehner, M; Wolf, S; Fagerberg, C; Bygum, A; Altmüller, J; Rütten, A; Parmentier, L; El Shabrawi-Caelen, L; Hafner, C; Nürnberg, P; Kruse, R; Schoch, S; Hanneken, S; Betz, RC Mutations in POGLUT1, encoding protein O-glucosyltransferase 1, cause autosomal-dominant Dowling-Degos disease.
Am J Hum Genet. 2014; 94(1):135-143 Doi: 10.1016/j.ajhg.2013.12.003 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Goessweiner-Mohr, N; Eder, M; Hofer, G; Fercher, C; Arends, K; Birner-Gruenberger, R; Grohmann, E; Keller, W Structure of the double-stranded DNA-binding type IV secretion protein TraN from Enterococcus.
Acta Crystallogr D Biol Crystallogr. 2014; 70(Pt 9):2376-2389 Doi: 10.1107/S1399004714014187 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Huang, JR; Warner, LR; Sanchez, C; Gabel, F; Madl, T; Mackereth, CD; Sattler, M; Blackledge, M Transient electrostatic interactions dominate the conformational equilibrium sampled by multidomain splicing factor U2AF65: a combined NMR and SAXS study.
J Am Chem Soc. 2014; 136(19):7068-7076 Doi: 10.1021/ja502030n
Web of Science PubMed FullText FullText_MUG

 

Krump, C; Vogl, M; Brecker, L; Nidetzky, B; Kratzer, R Acceleration of an aldo-keto reductase by minimal loop engineering.
Protein Eng Des Sel. 2014; 27(7):245-248 Doi: 10.1093/protein/gzu021 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Lichtenegger, M; Groschner, K TRPC3: a multifunctional signaling molecule.
Handb Exp Pharmacol. 2014; 222: 67-84. Doi: 10.1007/978-3-642-54215-2_4
PubMed FullText FullText_MUG

 

2013

Lemke, JR; Lal, D; Reinthaler, EM; Steiner, I; Nothnagel, M; Alber, M; Geider, K; Laube, B; Schwake, M; Finsterwalder, K; Franke, A; Schilhabel, M; Jähn, JA; Muhle, H; Boor, R; Van Paesschen, W; Caraballo, R; Fejerman, N; Weckhuysen, S; De Jonghe, P; Larsen, J; Møller, RS; Hjalgrim, H; Addis, L; Tang, S; Hughes, E; Pal, DK; Veri, K; Vaher, U; Talvik, T; Dimova, P; Guerrero López, R; Serratosa, JM; Linnankivi, T; Lehesjoki, AE; Ruf, S; Wolff, M; Buerki, S; Wohlrab, G; Kroell, J; Datta, AN; Fiedler, B; Kurlemann, G; Kluger, G; Hahn, A; Haberlandt, DE; Kutzer, C; Sperner, J; Becker, F; Weber, YG; Feucht, M; Steinböck, H; Neophythou, B; Ronen, GM; Gruber-Sedlmayr, U; Geldner, J; Harvey, RJ; Hoffmann, P; Herms, S; Altmüller, J; Toliat, MR; Thiele, H; Nürnberg, P; Wilhelm, C; Stephani, U; Helbig, I; Lerche, H; Zimprich, F; Neubauer, BA; Biskup, S; von Spiczak, S Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes.
Nat Genet. 2013; 45(9):1067-1072 Doi: 10.1038/ng.2728
Web of Science PubMed FullText FullText_MUG

 

2012

Bassler, J; Klein, I; Schmidt, C; Kallas, M; Thomson, E; Wagner, MA; Bradatsch, B; Rechberger, G; Strohmaier, H; Hurt, E; Bergler, H; The Conserved Bud20 Zinc Finger Protein Is a New Component of the Ribosomal 60S Subunit Export Machinery.
MOL CELL BIOL. 2012; 32(24): 4898-4912. Doi: 10.1128/MCB.00910-12 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Damm, M; Nusshold, C; Cantillo, D; Rechberger, GN; Gruber, K; Sattler, W; Kappe, CO Can electromagnetic fields influence the structure and enzymatic digest of proteins? A critical evaluation of microwave-assisted proteomics protocols.
J Proteomics. 2012; 75(18):5533-5543 Doi: 10.1016/j.jprot.2012.07.043 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Khafaga, M; Bossuyt, J; Mamikonian, L; Li, JC; Lee, LL; Yarov-Yarovoy, V; Despa, S; Bers, DM Na⁺/K⁺-ATPase E960 and phospholemman F28 are critical for their functional interaction.
Proc Natl Acad Sci U S A. 2012; 109(50):20756-20761 Doi: 10.1073/pnas.1207866109 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2011

Muik, M; Fahrner, M; Schindl, R; Stathopulos, P; Frischauf, I; Derler, I; Plenk, P; Lackner, B; Groschner, K; Ikura, M; Romanin, C STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation.
EMBO J. 2011; 30(9): 1678-1689. Doi: 10.1038/emboj.2011.79 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG Google Scholar

 

Norville, IH; Breitbach, K; Eske-Pogodda, K; Harmer, NJ; Sarkar-Tyson, M; Titball, RW; Steinmetz, I A novel FK-506-binding-like protein that lacks peptidyl-prolyl isomerase activity is involved in intracellular infection and in vivo virulence of Burkholderia pseudomallei.
Microbiology. 2011; 157(Pt 9):2629-2638 Doi: 10.1099/mic.0.049163-0 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Rotthier, A; Penno, A; Rautenstrauss, B; Auer-Grumbach, M; Stettner, GM; Asselbergh, B; Van Hoof, K; Sticht, H; Levy, N; Timmerman, V; Hornemann, T; Janssens, K Characterization of Two Mutations in the SPTLC1 Subunit of Serine Palmitoyltransferase Associated with Hereditary Sensory and Autonomic Neuropathy Type I
HUM MUTAT. 2011; 32(6): E2211-E2225. Doi: 10.1002/humu.21481 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG Google Scholar

 

Wolf, D; Hohmann, JD; Wiedemann, A; Bledzka, K; Blankenbach, H; Marchini, T; Gutte, K; Zeschky, K; Bassler, N; Hoppe, N; Rodriguez, AO; Herr, N; Hilgendorf, I; Stachon, P; Willecke, F; Duerschmied, D; von zur Muhlen, C; Soloviev, DA; Zhang, L; Bode, C; Plow, EF; Libby, P; Peter, K; Zirlik, A Binding of CD40L to Mac-1's I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice.
CIRC RES. 2011; 109(11): 1269-1279. Doi: 10.1161/CIRCRESAHA.111.247684 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2010

Madl, T; Felli, IC; Bertini, I; Sattler, M Structural analysis of protein interfaces from 13C direct-detected paramagnetic relaxation enhancements.
J Am Chem Soc. 2010; 132(21): 7285-7287. Doi: 10.1021/ja1014508
Web of Science PubMed FullText FullText_MUG

 

Mueller, M; Kratzer, R; Schiller, M; Slavica, A; Rechberger, G; Kollroser, M; Nidetzky, B The role of Cys108 in Trigonopsis variabilisd-amino acid oxidase examined through chemical oxidation studies and point mutations C108S and C108D.
Biochim Biophys Acta. 2010; 1804(7):1483-1491 Doi: 10.1016/j.bbapap.2010.02.009 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

2009

Madl, T; Sattler, M Adhesion dance with raver.
Structure. 2009; 17(6): 781-783. Doi: 10.1016/j.str.2009.05.004
Web of Science PubMed FullText FullText_MUG

 

Pippal, JB; Yao, Y; Rogerson, FM; Fuller, PJ Structural and functional characterization of the interdomain interaction in the mineralocorticoid receptor.
Mol Endocrinol. 2009; 23(9):1360-1370 Doi: 10.1210/me.2009-0032 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Vardatsikos, G; Sahu, A; Srivastava, AK The insulin-like growth factor family: molecular mechanisms, redox regulation, and clinical implications.
Antioxid Redox Signal. 2009; 11(5):1165-1190 Doi: 10.1089/ARS.2008.2161
Web of Science PubMed FullText FullText_MUG

 

2006

Johs, A; Hammel, M; Waldner, I; May, RP; Laggner, P; Prassl, R Modular structure of solubilized human apolipoprotein B-100 - Low resolution model revealed by small angle neutron scattering
J Biol Chem. 2006; 281(28):19732-19739 Doi: 10.1074/jbc.M601688200 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

2005

Schühly, W; Crockett, SL; Fabian, WM Hyperolactone C: determination of its absolute configuration by comparison of experimental and calculated CD spectra.
Chirality. 2005; 17(5):250-256 Doi: 10.1002/chir.20164
Web of Science PubMed FullText FullText_MUG

 

2004

Krebs, A; Durchschlag, H; Zipper, P Small angle X-ray scattering studies and modeling of Eudistylia vancouverii chlorocruorin and Macrobdella decora hemoglobin.
Biophys J. 2004; 87(2):1173-1185 Doi: 10.1529/biophysj.103.037929 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Krebs, A; Goldie, KN; Hoenger, A Complex formation with kinesin motor domains affects the structure of microtubules.
J Mol Biol. 2004; 335(1):139-153 Doi: 10.1016/j.jmb.2003.10.039
Web of Science PubMed FullText FullText_MUG

 

2003

Hasegawa, H; Zinsser, S; Rhee, Y; Vik-Mo, EO; Davanger, S; Hay, JC Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain.
Mol Biol Cell. 2003; 14(2):698-720 Doi: 10.1091/mbc.E02-09-0556 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Krebs, A; Edwards, PC; Villa, C; Li, J; Schertler, GF The three-dimensional structure of bovine rhodopsin determined by electron cryomicroscopy.
J Biol Chem. 2003; 278(50):50217-50225 Doi: 10.1074/jbc.M307995200 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

2002

Gutiérrez-González, LH; Ludwig, C; Hohoff, C; Rademacher, M; Hanhoff, T; Rüterjans, H; Spener, F; Lücke, C Solution structure and backbone dynamics of human epidermal-type fatty acid-binding protein (E-FABP).
Biochem J. 2002; 364(Pt 3):725-737 Doi: 10.1042/BJ20020039 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG Google Scholar

 

2001

Ahammer, H; DeVaney, TT; Tritthart, HA Fractal dimension of K1735 mouse melanoma clones and spheroid invasion in vitro.
Eur Biophys J. 2001; 30(7):494-499 Doi: 10.1007/s002490100173
Web of Science PubMed FullText FullText_MUG

 

Davies, A; Gowen, BE; Krebs, AM; Schertler, GF; Saibil, HR Three-dimensional structure of an invertebrate rhodopsin and basis for ordered alignment in the photoreceptor membrane.
J Mol Biol. 2001; 314(3):455-463 Doi: 10.1006/jmbi.2001.5167
Web of Science PubMed FullText FullText_MUG

 

2000

Abbadi, A; Brummel, M; Spener, F Knockout of the regulatory site of 3-ketoacyl-ACP synthase III enhances short- and medium-chain acyl-ACP synthesis.
Plant J. 2000; 24(1):1-9 Doi: 10.1046/j.1365-313x.2000.00841.x [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Balendiran, GK; Schnutgen, F; Scapin, G; Borchers, T; Xhong, N; Lim, K; Godbout, R; Spener, F; Sacchettini, JC Crystal structure and thermodynamic analysis of human brain fatty acid-binding protein.
J Biol Chem. 2000; 275(35):27045-27054 Doi: 10.1074/jbc.M003001200 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG Google Scholar

 

Xu, D; Joglekar, AP; Williams, AL; Hay, JC Subunit structure of a mammalian ER/Golgi SNARE complex.
J Biol Chem. 2000; 275(50):39631-39639 Doi: 10.1074/jbc.M007684200 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

1999

Graupner, M; Haalck, L; Spener, F; Lindner, H; Glatter, O; Paltauf, F; Hermetter, A Molecular dynamics of microbial lipases as determined from their intrinsic tryptophan fluorescence.
Biophys J. 1999; 77(1):493-504 Doi: 10.1016/S0006-3495(99)76906-7 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG Google Scholar

 

1998

Krebs, A; Lamy, J; Vinogradov, SN; Zipper, P Lumbricus terrestris hemoglobin: a comparison of small-angle x-ray scattering and cryoelectron microscopy data.
Biopolymers. 1998; 45(4):289-298 Doi: 10.1002/(SICI)1097-0282(19980405)45:4<289::AID-BIP3>3.0.CO;2-H
Web of Science PubMed FullText FullText_MUG

 

Weitere 50 Treffer anzeigen

↑ Seitenanfang / Navigation

© Med Uni Graz • Impressum