Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: PROTEIN CONFORMATION - , . Treffer: 45

2017

Byrgazov, K; Kastner, R; Gorna, M; Hoermann, G; Koenig, M; Lucini, CB; Ulreich, R; Benesch, M; Strenger, V; Lackner, H; Schwinger, W; Sovinz, P; Haas, OA; van den Heuvel-Eibrink, M; Niemeyer, CM; Hantschel, O; Valent, P; Superti-Furga, G; Urban, C; Dworzak, MN; Lion, T NDEL1-PDGFRB fusion gene in a myeloid malignancy with eosinophilia associated with resistance to tyrosine kinase inhibitors.
Leukemia. 2017; 31(1):237-240 [OPEN ACCESS]
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2016

Anvarian, Z; Nojima, H; van Kappel, EC; Madl, T; Spit, M; Viertler, M; Jordens, I; Low, TY; van Scherpenzeel, RC; Kuper, I; Richter, K; Heck, AJ; Boelens, R; Vincent, JP; Rüdiger, SG; Maurice, MM Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network.
Nat Struct Mol Biol. 2016; 23(4):324-332
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Aschauer, P; Rengachari, S; Lichtenegger, J; Schittmayer, M; Das, KM; Mayer, N; Breinbauer, R; Birner-Gruenberger, R; Gruber, CC; Zimmermann, R; Gruber, K; Oberer, M Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p.
Biochim Biophys Acta. 2016; 1861(5):462-470 [OPEN ACCESS]
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Biundo, A; Hromic, A; Pavkov-Keller, T; Gruber, K; Quartinello, F; Haernvall, K; Perz, V; Arrell, MS; Zinn, M; Ribitsch, D; Guebitz, GM Characterization of a poly(butylene adipate-co-terephthalate)- hydrolyzing lipase from Pelosinus fermentans.
Appl Microbiol Biotechnol. 2016; 100(4): 1753-1764. [OPEN ACCESS]
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Hartlmüller, C; Göbl, C; Madl, T Prediction of Protein Structure Using Surface Accessibility Data.
Angew Chem Int Ed Engl. 2016; 55(39):11970-11974 [OPEN ACCESS]
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Perz, V; Baumschlager, A; Bleymaier, K; Zitzenbacher, S; Hromic, A; Steinkellner, G; Pairitsch, A; Łyskowski, A; Gruber, K; Sinkel, C; Küper, U; Ribitsch, D; Guebitz, GM Hydrolysis of synthetic polyesters by Clostridium botulinum esterases.
Biotechnol Bioeng. 2016; 113(5): 1024-1034.
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Voith von Voithenberg, L; Sánchez-Rico, C; Kang, HS; Madl, T; Zanier, K; Barth, A; Warner, LR; Sattler, M; Lamb, DC Recognition of the 3' splice site RNA by the U2AF heterodimer involves a dynamic population shift.
Proc Natl Acad Sci U S A. 2016; 113(46):E7169-E7175 [OPEN ACCESS]
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Weber, J; Bao, H; Hartlmüller, C; Wang, Z; Windhager, A; Janowski, R; Madl, T; Jin, P; Niessing, D Structural basis of nucleic-acid recognition and double-strand unwinding by the essential neuronal protein Pur-alpha.
Elife. 2016; 5(7): [OPEN ACCESS]
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Zierer, BK; Rübbelke, M; Tippel, F; Madl, T; Schopf, FH; Rutz, DA; Richter, K; Sattler, M; Buchner, J Importance of cycle timing for the function of the molecular chaperone Hsp90.
Nat Struct Mol Biol. 2016; 23(11):1020-1028 [OPEN ACCESS]
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2015

Chromikova, V; Mader, A; Hofbauer, S; Göbl, C; Madl, T; Gach, JS; Bauernfried, S; Furtmüller, PG; Forthal, DN; Mach, L; Obinger, C; Kunert, R Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM.
Biochim Biophys Acta. 2015; 1854(10 Pt A):1536-1544 [OPEN ACCESS]
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Gersch, M; Famulla, K; Dahmen, M; Göbl, C; Malik, I; Richter, K; Korotkov, VS; Sass, P; Rübsamen-Schaeff, H; Madl, T; Brötz-Oesterhelt, H; Sieber, SA AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control.
Nat Commun. 2015; 6(2):6320-6320 [OPEN ACCESS]
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2014

Basmanav, FB; Oprisoreanu, AM; Pasternack, SM; Thiele, H; Fritz, G; Wenzel, J; Größer, L; Wehner, M; Wolf, S; Fagerberg, C; Bygum, A; Altmüller, J; Rütten, A; Parmentier, L; El Shabrawi-Caelen, L; Hafner, C; Nürnberg, P; Kruse, R; Schoch, S; Hanneken, S; Betz, RC Mutations in POGLUT1, encoding protein O-glucosyltransferase 1, cause autosomal-dominant Dowling-Degos disease.
Am J Hum Genet. 2014; 94(1):135-143 [OPEN ACCESS]
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Goessweiner-Mohr, N; Eder, M; Hofer, G; Fercher, C; Arends, K; Birner-Gruenberger, R; Grohmann, E; Keller, W Structure of the double-stranded DNA-binding type IV secretion protein TraN from Enterococcus.
Acta Crystallogr D Biol Crystallogr. 2014; 70(Pt 9):2376-2389 [OPEN ACCESS]
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Huang, JR; Warner, LR; Sanchez, C; Gabel, F; Madl, T; Mackereth, CD; Sattler, M; Blackledge, M Transient electrostatic interactions dominate the conformational equilibrium sampled by multidomain splicing factor U2AF65: a combined NMR and SAXS study.
J Am Chem Soc. 2014; 136(19):7068-7076
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Krump, C; Vogl, M; Brecker, L; Nidetzky, B; Kratzer, R Acceleration of an aldo-keto reductase by minimal loop engineering.
Protein Eng Des Sel. 2014; 27(7):245-248 [OPEN ACCESS]
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Lichtenegger, M; Groschner, K TRPC3: a multifunctional signaling molecule.
Handb Exp Pharmacol. 2014; 222: 67-84.
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2013

Lemke, JR; Lal, D; Reinthaler, EM; Steiner, I; Nothnagel, M; Alber, M; Geider, K; Laube, B; Schwake, M; Finsterwalder, K; Franke, A; Schilhabel, M; Jähn, JA; Muhle, H; Boor, R; Van Paesschen, W; Caraballo, R; Fejerman, N; Weckhuysen, S; De Jonghe, P; Larsen, J; Møller, RS; Hjalgrim, H; Addis, L; Tang, S; Hughes, E; Pal, DK; Veri, K; Vaher, U; Talvik, T; Dimova, P; Guerrero López, R; Serratosa, JM; Linnankivi, T; Lehesjoki, AE; Ruf, S; Wolff, M; Buerki, S; Wohlrab, G; Kroell, J; Datta, AN; Fiedler, B; Kurlemann, G; Kluger, G; Hahn, A; Haberlandt, DE; Kutzer, C; Sperner, J; Becker, F; Weber, YG; Feucht, M; Steinböck, H; Neophythou, B; Ronen, GM; Gruber-Sedlmayr, U; Geldner, J; Harvey, RJ; Hoffmann, P; Herms, S; Altmüller, J; Toliat, MR; Thiele, H; Nürnberg, P; Wilhelm, C; Stephani, U; Helbig, I; Lerche, H; Zimprich, F; Neubauer, BA; Biskup, S; von Spiczak, S Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes.
Nat Genet. 2013; 45(9):1067-1072
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2012

Bassler, J; Klein, I; Schmidt, C; Kallas, M; Thomson, E; Wagner, MA; Bradatsch, B; Rechberger, G; Strohmaier, H; Hurt, E; Bergler, H; The Conserved Bud20 Zinc Finger Protein Is a New Component of the Ribosomal 60S Subunit Export Machinery.
MOL CELL BIOL. 2012; 32(24): 4898-4912. [OPEN ACCESS]
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Damm, M; Nusshold, C; Cantillo, D; Rechberger, GN; Gruber, K; Sattler, W; Kappe, CO Can electromagnetic fields influence the structure and enzymatic digest of proteins? A critical evaluation of microwave-assisted proteomics protocols.
J Proteomics. 2012; 75(18):5533-5543 [OPEN ACCESS]
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Khafaga, M; Bossuyt, J; Mamikonian, L; Li, JC; Lee, LL; Yarov-Yarovoy, V; Despa, S; Bers, DM Na⁺/K⁺-ATPase E960 and phospholemman F28 are critical for their functional interaction.
Proc Natl Acad Sci U S A. 2012; 109(50):20756-20761 [OPEN ACCESS]
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2011

Muik, M; Fahrner, M; Schindl, R; Stathopulos, P; Frischauf, I; Derler, I; Plenk, P; Lackner, B; Groschner, K; Ikura, M; Romanin, C STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation.
EMBO J. 2011; 30(9): 1678-1689. [OPEN ACCESS]
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Norville, IH; Breitbach, K; Eske-Pogodda, K; Harmer, NJ; Sarkar-Tyson, M; Titball, RW; Steinmetz, I A novel FK-506-binding-like protein that lacks peptidyl-prolyl isomerase activity is involved in intracellular infection and in vivo virulence of Burkholderia pseudomallei.
Microbiology. 2011; 157(Pt 9):2629-2638 [OPEN ACCESS]
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Rotthier, A; Penno, A; Rautenstrauss, B; Auer-Grumbach, M; Stettner, GM; Asselbergh, B; Van Hoof, K; Sticht, H; Levy, N; Timmerman, V; Hornemann, T; Janssens, K Characterization of Two Mutations in the SPTLC1 Subunit of Serine Palmitoyltransferase Associated with Hereditary Sensory and Autonomic Neuropathy Type I
HUM MUTAT. 2011; 32(6): E2211-E2225. [OPEN ACCESS]
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Wolf, D; Hohmann, JD; Wiedemann, A; Bledzka, K; Blankenbach, H; Marchini, T; Gutte, K; Zeschky, K; Bassler, N; Hoppe, N; Rodriguez, AO; Herr, N; Hilgendorf, I; Stachon, P; Willecke, F; Duerschmied, D; von zur Muhlen, C; Soloviev, DA; Zhang, L; Bode, C; Plow, EF; Libby, P; Peter, K; Zirlik, A Binding of CD40L to Mac-1's I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice.
CIRC RES. 2011; 109(11): 1269-1279. [OPEN ACCESS]
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2010

Madl, T; Felli, IC; Bertini, I; Sattler, M Structural analysis of protein interfaces from 13C direct-detected paramagnetic relaxation enhancements.
J Am Chem Soc. 2010; 132(21): 7285-7287.
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Mueller, M; Kratzer, R; Schiller, M; Slavica, A; Rechberger, G; Kollroser, M; Nidetzky, B The role of Cys108 in Trigonopsis variabilisd-amino acid oxidase examined through chemical oxidation studies and point mutations C108S and C108D.
Biochim Biophys Acta. 2010; 1804(7):1483-1491 [OPEN ACCESS]
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2009

Madl, T; Sattler, M Adhesion dance with raver.
Structure. 2009; 17(6): 781-783.
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Pippal, JB; Yao, Y; Rogerson, FM; Fuller, PJ Structural and functional characterization of the interdomain interaction in the mineralocorticoid receptor.
Mol Endocrinol. 2009; 23(9):1360-1370 [OPEN ACCESS]
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Vardatsikos, G; Sahu, A; Srivastava, AK The insulin-like growth factor family: molecular mechanisms, redox regulation, and clinical implications.
Antioxid Redox Signal. 2009; 11(5):1165-1190
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2006

Johs, A; Hammel, M; Waldner, I; May, RP; Laggner, P; Prassl, R Modular structure of solubilized human apolipoprotein B-100 - Low resolution model revealed by small angle neutron scattering
J Biol Chem. 2006; 281(28):19732-19739 [OPEN ACCESS]
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2005

Schühly, W; Crockett, SL; Fabian, WM Hyperolactone C: determination of its absolute configuration by comparison of experimental and calculated CD spectra.
Chirality. 2005; 17(5):250-256
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2003

Hasegawa, H; Zinsser, S; Rhee, Y; Vik-Mo, EO; Davanger, S; Hay, JC Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain.
Mol Biol Cell. 2003; 14(2):698-720 [OPEN ACCESS]
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2002

Gutiérrez-González, LH; Ludwig, C; Hohoff, C; Rademacher, M; Hanhoff, T; Rüterjans, H; Spener, F; Lücke, C Solution structure and backbone dynamics of human epidermal-type fatty acid-binding protein (E-FABP).
Biochem J. 2002; 364(Pt 3):725-737 [OPEN ACCESS]
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2001

Ahammer, H; DeVaney, TT; Tritthart, HA Fractal dimension of K1735 mouse melanoma clones and spheroid invasion in vitro.
Eur Biophys J. 2001; 30(7):494-499
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2000

Abbadi, A; Brummel, M; Spener, F Knockout of the regulatory site of 3-ketoacyl-ACP synthase III enhances short- and medium-chain acyl-ACP synthesis.
Plant J. 2000; 24(1):1-9 [OPEN ACCESS]
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Balendiran, GK; Schnutgen, F; Scapin, G; Borchers, T; Xhong, N; Lim, K; Godbout, R; Spener, F; Sacchettini, JC Crystal structure and thermodynamic analysis of human brain fatty acid-binding protein.
J Biol Chem. 2000; 275(35):27045-27054 [OPEN ACCESS]
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Xu, D; Joglekar, AP; Williams, AL; Hay, JC Subunit structure of a mammalian ER/Golgi SNARE complex.
J Biol Chem. 2000; 275(50):39631-39639 [OPEN ACCESS]
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1999

Graupner, M; Haalck, L; Spener, F; Lindner, H; Glatter, O; Paltauf, F; Hermetter, A Molecular dynamics of microbial lipases as determined from their intrinsic tryptophan fluorescence.
Biophys J. 1999; 77(1):493-504 [OPEN ACCESS]
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1998

Scheib, H; Pleiss, J; Stadler, P; Kovac, A; Potthoff, AP; Haalck, L; Spener, F; Paltauf, F; Schmid, RD Rational design of Rhizopus oryzae lipase with modified stereoselectivity toward triradylglycerols.
Protein Eng. 1998; 11(8):675-682 [OPEN ACCESS]
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1997

Höfer, GF; Hohenthanner, K; Baumgartner, W; Groschner, K; Klugbauer, N; Hofmann, F; Romanin, C Intracellular Ca2+ inactivates L-type Ca2+ channels with a Hill coefficient of approximately 1 and an inhibition constant of approximately 4 microM by reducing channel's open probability.
Biophys J. 1997; 73(4):1857-1865 [OPEN ACCESS]
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1996

Lang, D; Hofmann, B; Haalck, L; Hecht, HJ; Spener, F; Schmid, RD; Schomburg, D Crystal structure of a bacterial lipase from Chromobacterium viscosum ATCC 6918 refined at 1.6 angstroms resolution.
J Mol Biol. 1996; 259(4):704-717
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1995

BECKER, JC; NIKROO, A; BRABLETZ, T; REISFELD, RA DNA loops induced by cooperative binding of transcriptional activator proteins and preinitiation complexes.
Proc Natl Acad Sci U S A. 1995; 92(21):9727-9731 [OPEN ACCESS]
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1991

Müller-Fahrnow, A; Egner, U; Jones, TA; Rüdel, H; Spener, F; Saenger, W Three-dimensional structure of fatty-acid-binding protein from bovine heart.
Eur J Biochem. 1991; 199(2):271-276
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1988

Billich, S; Wissel, T; Kratzin, H; Hahn, U; Hagenhoff, B; Lezius, AG; Spener, F Cloning of a full-length complementary DNA for fatty-acid-binding protein from bovine heart.
Eur J Biochem. 1988; 175(3):549-556
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1985

Pähler, A; Maslowska, M; Parge, HE; Schneider, M; Steifa, M; Saenger, W; Keuper, HJ; Spener, F X-ray studies on triclinic crystals of fatty acid binding protein. Examples of an extremely X-ray-resistant protein.
FEBS Lett. 1985; 184(2):185-187
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