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Publikationen

Suchbegriffe: PROMOTER REGIONS, GENETIC - , . Treffer: 103

2022

Vogl, T Engineering of Promoters for Gene Expression in Pichia pastoris.
Methods Mol Biol. 2022; 2513:153-177 Doi: 10.1007/978-1-0716-2399-2_10
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2021

Pan, G; Diamanti, K; Cavalli, M; Lara, Gutiérrez, A; Komorowski, J; Wadelius, C Multifaceted regulation of hepatic lipid metabolism by YY1.
Life Sci Alliance. 2021; 4(7): Doi: 10.26508/lsa.202000928 [OPEN ACCESS]
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2020

Buxhofer-Ausch, V; Ausch, C; Reiner, A; Müllner-Ammer, K; Schmid, A; Kriwanek, S; Sebesta, C; Halwachs-Baumann, G; Kriegshäuser, G SFRP1 promotor methylation analysis of FTA card touch-prep samples derived from colonic polyps.
Exp Mol Pathol. 2020; 114(9):104397-104397 Doi: 10.1016/j.yexmp.2020.104397
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Marquard, S; Thomann, S; Weiler, SME; Bissinger, M; Lutz, T; Sticht, C; Tóth, M; de, la, Torre, C; Gretz, N; Straub, BK; Marquardt, J; Schirmacher, P; Breuhahn, K Yes-associated protein (YAP) induces a secretome phenotype and transcriptionally regulates plasminogen activator Inhibitor-1 (PAI-1) expression in hepatocarcinogenesis.
Cell Commun Signal. 2020; 18(1): 166 Doi: 10.1186/s12964-020-00634-6 [OPEN ACCESS]
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2018

Micko, ASG; Höftberger, R; Wöhrer, A; Millesi, M; Knosp, E; Wolfsberger, S MGMT assessment in pituitary adenomas: comparison of different immunohistochemistry fixation chemicals.
Pituitary. 2018; 21(3):266-273 Doi: 10.1007/s11102-018-0862-x [OPEN ACCESS]
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2017

Fuchs, CD; Claudel, T; Scharnagl, H; Stojakovic, T; Trauner, M FXR controls CHOP expression in steatohepatitis.
FEBS Lett. 2017; 591(20):3360-3368 Doi: 10.1002/1873-3468.12845 [OPEN ACCESS]
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Kriegshäuser, G; Enko, D; Zitt, M; Oberwalder, M; Oberkanins, C; Öfner, D; Zeillinger, R; Maximilian Müller, H Comparison of a prototype reverse hybridization assay and MethyLight for detection of SFRP2 promotor methylation in fecal DNA.
Int J Biol Markers. 2017; 32(4):e467-e470-e467-e470 Doi: 10.5301/ijbm.5000289 [OPEN ACCESS]
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Ofner, R; Ritter, C; Heidenreich, B; Kumar, R; Ugurel, S; Schrama, D; Becker, JC Distribution of TERT promoter mutations in primary and metastatic melanomas in Austrian patients.
J Cancer Res Clin Oncol. 2017; 143(4):613-617 Doi: 10.1007/s00432-016-2322-1 [OPEN ACCESS]
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Sheffield, NC; Pierron, G; Klughammer, J; Datlinger, P; Schönegger, A; Schuster, M; Hadler, J; Surdez, D; Guillemot, D; Lapouble, E; Freneaux, P; Champigneulle, J; Bouvier, R; Walder, D; Ambros, IM; Hutter, C; Sorz, E; Amaral, AT; de Álava, E; Schallmoser, K; Strunk, D; Rinner, B; Liegl-Atzwanger, B; Huppertz, B; Leithner, A; de Pinieux, G; Terrier, P; Laurence, V; Michon, J; Ladenstein, R; Holter, W; Windhager, R; Dirksen, U; Ambros, PF; Delattre, O; Kovar, H; Bock, C; Tomazou, EM DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.
Nat Med. 2017; 23(3):386-395 Doi: 10.1038/nm.4273 [OPEN ACCESS]
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Zeimet, AG; Mori, H; Petru, E; Polterauer, S; Reinthaller, A; Schauer, C; Scholl-Firon, T; Singer, C; Wimmer, K; Zschocke, J; Marth, C AGO Austria recommendation on screening and diagnosis of Lynch syndrome (LS).
ARCH GYNECOL OBSTET. 2017; 296(1): 123-127. Doi: 10.1007/s00404-017-4392-y [OPEN ACCESS]
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2016

Prokesch, A; Pelzmann, HJ; Pessentheiner, AR; Huber, K; Madreiter-Sokolowski, CT; Drougard, A; Schittmayer, M; Kolb, D; Magnes, C; Trausinger, G; Graier, WF; Birner-Gruenberger, R; Pospisilik, JA; Bogner-Strauss, JG N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes.
Sci Rep. 2016; 6(3):23723-23723 Doi: 10.1038/srep23723 [OPEN ACCESS]
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Ritter, C; Fan, K; Paulson, KG; Nghiem, P; Schrama, D; Becker, JC Reversal of epigenetic silencing of MHC class I chain-related protein A and B improves immune recognition of Merkel cell carcinoma.
Sci Rep. 2016; 6:21678-21678 Doi: 10.1038/srep21678 [OPEN ACCESS]
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2015

Fisser, MC; Rommer, A; Steinleitner, K; Heller, G; Herbst, F; Wiese, M; Glimm, H; Sill, H; Wieser, R Induction of the proapoptotic tumor suppressor gene Cell Adhesion Molecule 1 by chemotherapeutic agents is repressed in therapy resistant acute myeloid leukemia.
Mol Carcinog. 2015; 54(12):1815-1819 Doi: 10.1002/mc.22252 [OPEN ACCESS]
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Jagadeeshan, S; Krishnamoorthy, YR; Singhal, M; Subramanian, A; Mavuluri, J; Lakshmi, A; Roshini, A; Baskar, G; Ravi, M; Joseph, LD; Sadasivan, K; Krishnan, A; Nair, AS; Venkatraman, G; Rayala, SK Transcriptional regulation of fibronectin by p21-activated kinase-1 modulates pancreatic tumorigenesis.
Oncogene. 2015; 34(4): 455-464. Doi: 10.1038/onc.2013.576
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Knabl, J; Hiden, U; Hüttenbrenner, R; Riedel, C; Hutter, S; Kirn, V; Günthner-Biller, M; Desoye, G; Kainer, F; Jeschke, U GDM Alters Expression of Placental Estrogen Receptor α in a Cell Type and Gender-Specific Manner.
Reprod Sci. 2015; 22(12):1488-1495 Doi: 10.1177/1933719115585147 [OPEN ACCESS]
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Laszlo, V; Hoda, MA; Garay, T; Pirker, C; Ghanim, B; Klikovits, T; Dong, YW; Rozsas, A; Kenessey, I; Szirtes, I; Grusch, M; Jakopovic, M; Samarzija, M; Brcic, L; Kern, I; Rozman, A; Popper, H; Zöchbauer-Müller, S; Heller, G; Altenberger, C; Ziegler, B; Klepetko, W; Berger, W; Dome, B; Hegedus, B Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma.
J Pathol. 2015; 237(2):203-214 Doi: 10.1002/path.4567
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Shain, AH; Garrido, M; Botton, T; Talevich, E; Yeh, I; Sanborn, JZ; Chung, J; Wang, NJ; Kakavand, H; Mann, GJ; Thompson, JF; Wiesner, T; Roy, R; Olshen, AB; Gagnon, A; Gray, JW; Huh, N; Hur, JS; Busam, KJ; Scolyer, RA; Cho, RJ; Murali, R; Bastian, BC Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway.
Nat Genet. 2015; 47(10): 1194-1199. Doi: 10.1038/ng.3382 [OPEN ACCESS]
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2014

Fröhlich, LF; Mrakovcic, M; Smole, C; Lahiri, P; Zatloukal, K Epigenetic silencing of apoptosis-inducing gene expression can be efficiently overcome by combined SAHA and TRAIL treatment in uterine sarcoma cells.
PLoS One. 2014; 9(3):e91558-e91558 Doi: 10.1371/journal.pone.0091558 [OPEN ACCESS]
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Heidenreich, B; Nagore, E; Rachakonda, PS; Garcia-Casado, Z; Requena, C; Traves, V; Becker, J; Soufir, N; Hemminki, K; Kumar, R Telomerase reverse transcriptase promoter mutations in primary cutaneous melanoma.
Nat Commun. 2014; 5(5):3401-3401 Doi: 10.1038/ncomms4401 [OPEN ACCESS]
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Mellitzer, A; Ruth, C; Gustafsson, C; Welch, M; Birner-Grünberger, R; Weis, R; Purkarthofer, T; Glieder, A Synergistic modular promoter and gene optimization to push cellulase secretion by Pichia pastoris beyond existing benchmarks.
J Biotechnol. 2014; 191(1):187-195 Doi: 10.1016/j.jbiotec.2014.08.035
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Moazedi-Fuerst, FC; Hofner, M; Gruber, G; Weinhaeusel, A; Stradner, MH; Angerer, H; Peischler, D; Lohberger, B; Glehr, M; Leithner, A; Sonntagbauer, M; Graninger, WB Epigenetic differences in human cartilage between mild and severe OA.
J Orthop Res. 2014; 32(12):1636-1645 Doi: 10.1002/jor.22722 [OPEN ACCESS]
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Pereira, TV; Kimura, L; Suwazono, Y; Nakagawa, H; Daimon, M; Oizumi, T; Kayama, T; Kato, T; Li, L; Chen, S; Gu, D; Renner, W; März, W; Yamada, Y; Bagos, PG; Mingroni-Netto, RC Multivariate meta-analysis of the association of G-protein beta 3 gene (GNB3) haplotypes with cardiovascular phenotypes.
Mol Biol Rep. 2014; 41(5):3113-3125 Doi: 10.1007/s11033-014-3171-0 [OPEN ACCESS]
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Pradhan, SA; Rather, MI; Tiwari, A; Bhat, VK; Kumar, A Evidence that TSC2 acts as a transcription factor and binds to and represses the promoter of Epiregulin.
Nucleic Acids Res. 2014; 42(10): 6243-6255. Doi: 10.1093/nar/gku278 [OPEN ACCESS]
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Ress, AL; Stiegelbauer, V; Schwarzenbacher, D; Deutsch, A; Perakis, S; Ling, H; Ivan, C; Calin, GA; Rinner, B; Gerger, A; Pichler, M Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer.
Oncotarget. 2014; 5(18):8492-8502 Doi: 10.18632/oncotarget.2329 [OPEN ACCESS]
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Rossmann, C; Windpassinger, C; Brunner, D; Kovacevic, A; Schweighofer, N; Malli, R; Schuligoi, R; Prokesch, A; Kluve-Beckerman, B; Graier, WF; Kratky, D; Sattler, W; Malle, E Characterization of rat serum amyloid A4 (SAA4): a novel member of the SAA superfamily.
Biochem Biophys Res Commun. 2014; 450(4):1643-1649 Doi: 10.1016/j.bbrc.2014.07.054 [OPEN ACCESS]
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2013

Büttner, S; Faes, L; Reichelt, WN; Broeskamp, F; Habernig, L; Benke, S; Kourtis, N; Ruli, D; Carmona-Gutierrez, D; Eisenberg, T; D'hooge, P; Ghillebert, R; Franssens, V; Harger, A; Pieber, TR; Freudenberger, P; Kroemer, G; Sigrist, SJ; Winderickx, J; Callewaert, G; Tavernarakis, N; Madeo, F The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca(2+) levels to α-synuclein toxicity in Parkinson's disease models.
Cell Death Differ. 2013; 20(3):465-477 Doi: 10.1038/cdd.2012.142 [OPEN ACCESS]
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Duszka, K; Bogner-Strauss, JG; Hackl, H; Rieder, D; Neuhold, C; Prokesch, A; Trajanoski, Z; Krogsdam, AM Nr4a1 is required for fasting-induced down-regulation of Pparγ2 in white adipose tissue.
Mol Endocrinol. 2013; 27(1): 135-149. Doi: 10.1210/me.2012-1248 [OPEN ACCESS]
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Ho, JE; Chen, WY; Chen, MH; Larson, MG; McCabe, EL; Cheng, S; Ghorbani, A; Coglianese, E; Emilsson, V; Johnson, AD; Walter, S; Franceschini, N; O'Donnell, CJ; CARDIoGRAM Consortium; CHARGE Inflammation Working Group; Dehghan, A; Lu, C; Levy, D; Newton-Cheh, C; CHARGE Heart Failure Working Group; Lin, H; Felix, JF; Schreiter, ER; Vasan, RS; Januzzi, JL; Lee, RT; Wang, TJ; Assimes, TL; Deloukas, P; Erdmann, J; Holm, H; Kathiresan, S; König, IR; McPherson, R; Reilly, MP; Roberts, R; Samani, NJ; Schunkert, H; Stewart, AF Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling.
J Clin Invest. 2013; 123(10): 4208-4218. Doi: 10.1172/JCI67119 [OPEN ACCESS]
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Joo, JE; Hiden, U; Lassance, L; Gordon, L; Martino, DJ; Desoye, G; Saffery, R Variable promoter methylation contributes to differential expression of key genes in human placenta-derived venous and arterial endothelial cells.
BMC Genomics. 2013; 14(7):475-475 Doi: 10.1186/1471-2164-14-475 [OPEN ACCESS]
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Novakovic, B; Gordon, L; Robinson, WP; Desoye, G; Saffery, R Glucose as a fetal nutrient: dynamic regulation of several glucose transporter genes by DNA methylation in the human placenta across gestation.
J Nutr Biochem. 2013; 24(1):282-288 Doi: 10.1016/j.jnutbio.2012.06.006
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Senanayake, U; Koller, K; Pichler, M; Leuschner, I; Strohmaier, H; Hadler, U; Das, S; Hoefler, G; Guertl, B The pluripotent renal stem cell regulator SIX2 is activated in renal neoplasms and influences cellular proliferation and migration.
Hum Pathol. 2013; 44(3):336-345 Doi: 10.1016/j.humpath.2012.05.021
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Weidner, CI; Walenda, T; Lin, Q; Wölfler, MM; Denecke, B; Costa, IG; Zenke, M; Wagner, W Hematopoietic stem and progenitor cells acquire distinct DNA-hypermethylation during in vitro culture.
Sci Rep. 2013; 3(12):3372-3372 Doi: 10.1038/srep03372 [OPEN ACCESS]
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2012

Bisping, E; Ikeda, S; Sedej, M; Wakula, P; McMullen, JR; Tarnavski, O; Sedej, S; Izumo, S; Pu, WT; Pieske, B Transcription factor GATA4 is activated but not required for insulin-like growth factor 1 (IGF1)-induced cardiac hypertrophy.
J Biol Chem. 2012; 287(13):9827-9834 Doi: 10.1074/jbc.M111.338749 [OPEN ACCESS]
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Chennamsetty, I; Claudel, T; Kostner, KM; Trauner, M; Kostner, GM FGF19 signaling cascade suppresses APOA gene expression.
Arterioscler Thromb Vasc Biol. 2012; 32(5):1220-1227 Doi: 10.1161/ATVBAHA.111.243055 [OPEN ACCESS]
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Neumann, O; Kesselmeier, M; Geffers, R; Pellegrino, R; Radlwimmer, B; Hoffmann, K; Ehemann, V; Schemmer, P; Schirmacher, P; Lorenzo Bermejo, J; Longerich, T Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors.
Hepatology. 2012; 56(5):1817-1827 Doi: 10.1002/hep.25870 [OPEN ACCESS]
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Seleznik, GM; Reding, T; Romrig, F; Saito, Y; Mildner, A; Segerer, S; Sun, LK; Regenass, S; Lech, M; Anders, HJ; McHugh, D; Kumagi, T; Hiasa, Y; Lackner, C; Haybaeck, J; Angst, E; Perren, A; Balmer, ML; Slack, E; MacPherson, A; Manz, MG; Weber, A; Browning, JL; Arkan, MC; Rülicke, T; Aguzzi, A; Prinz, M; Graf, R; Heikenwalder, M Lymphotoxin β receptor signaling promotes development of autoimmune pancreatitis.
Gastroenterology. 2012; 143(5):1361-1374 Doi: 10.1053/j.gastro.2012.07.112 [OPEN ACCESS]
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Szkandera, J; Absenger, G; Stotz, M; Weissmueller, M; Winder, T; Langsenlehner, T; Samonigg, H; Renner, W; Schippinger, W; Gerger, A The Functional Polymorphism of Erythropoietin Gene rs1617640 G>T Is Not Associated with Susceptibility and Clinical Outcome of Early-stage Breast Cancer.
Anticancer Res. 2012; 32(8):3473-3478
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2011

Chen, F; Zhu, Y; Tang, X; Sun, Y; Jia, W; Sun, Y; Han, X Dynamic regulation of PDX-1 and FoxO1 expression by FoxA2 in dexamethasone-induced pancreatic β-cells dysfunction.
Endocrinology. 2011; 152(5): 1779-1788. Doi: 10.1210/en.2010-1048 [OPEN ACCESS]
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Chennamsetty, I; Claudel, T; Kostner, KM; Baghdasaryan, A; Kratky, D; Levak-Frank, S; Frank, S; Gonzalez, FJ; Trauner, M; Kostner, GM Farnesoid X receptor represses hepatic human APOA gene expression.
J Clin Invest. 2011; 121(9):3724-3734 Doi: 10.1172/JCI45277 [OPEN ACCESS]
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Dagdan, E; Morris, DW; Campbell, M; Hill, M; Rothermundt, M; Kästner, F; Hohoff, C; von Eiff, C; Krakowitzky, P; Gill, M; McKeon, P; Roche, S Functional assessment of a promoter polymorphism in S100B, a putative risk variant for bipolar disorder.
Am J Med Genet B Neuropsychiatr Genet. 2011; 156B(6):691-699 Doi: 10.1002/ajmg.b.31211
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Faoro, D; von Bueren, AO; Shalaby, T; Sciuscio, D; Hürlimann, ML; Arnold, L; Gerber, NU; Haybaeck, J; Mittelbronn, M; Rutkowski, S; Hegi, M; Grotzer, MA Expression of O⁶-methylguanine-DNA methyltransferase in childhood medulloblastoma.
J Neurooncol. 2011; 103(1):59-69 Doi: 10.1007/s11060-010-0366-7 [OPEN ACCESS]
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Hallen, L; Klein, H; Stoschek, C; Wehrmeyer, S; Nonhoff, U; Ralser, M; Wilde, J; Röhr, C; Schweiger, MR; Zatloukal, K; Vingron, M; Lehrach, H; Konthur, Z; Krobitsch, S The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2.
Hum Mol Genet. 2011; 20(1): 104-114. Doi: 10.1093/hmg/ddq436 [OPEN ACCESS]
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Putluri, N; Shojaie, A; Vasu, VT; Vareed, SK; Nalluri, S; Putluri, V; Thangjam, GS; Panzitt, K; Tallman, CT; Butler, C; Sana, TR; Fischer, SM; Sica, G; Brat, DJ; Shi, H; Palapattu, GS; Lotan, Y; Weizer, AZ; Terris, MK; Shariat, SF; Michailidis, G; Sreekumar, A Metabolomic profiling reveals potential markers and bioprocesses altered in bladder cancer progression.
Cancer Res. 2011; 71(24):7376-7386 Doi: 10.1158/0008-5472.CAN-11-1154 [OPEN ACCESS]
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Schmidt, H; Zeginigg, M; Wiltgen, M; Freudenberger, P; Petrovic, K; Cavalieri, M; Gider, P; Enzinger, C; Fornage, M; Debette, S; Rotter, JI; Ikram, MA; Launer, LJ; Schmidt, R; CHARGE consortium Neurology working group Genetic variants of the NOTCH3 gene in the elderly and magnetic resonance imaging correlates of age-related cerebral small vessel disease.
Brain. 2011; 134(Pt 11): 3384-3397. Doi: 10.1093/brain/awr252 [OPEN ACCESS]
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Wels, C; Joshi, S; Koefinger, P; Bergler, H; Schaider, H Transcriptional Activation of ZEB1 by Slug Leads to Cooperative Regulation of the Epithelial-Mesenchymal Transition-Like Phenotype in Melanoma
J INVEST DERMATOL. 2011; 131(9): 1877-1885. Doi: 10.1038/jid.2011.142 [OPEN ACCESS]
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Winder, T; Bohanes, P; Zhang, W; Yang, D; Power, DG; Ning, Y; Gerger, A; Wilson, PM; Tang, LH; Shah, M; Lee, AS; Lenz, HJ GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients.
Ann Oncol. 2011; 22(11):2431-2439 Doi: 10.1093/annonc/mdq771 [OPEN ACCESS]
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Zhang, Y; Lei, T; Huang, JF; Wang, SB; Zhou, LL; Yang, ZQ; Chen, XD The link between fibroblast growth factor 21 and sterol regulatory element binding protein 1c during lipogenesis in hepatocytes.
Mol Cell Endocrinol. 2011; 342(1-2): 41-47. Doi: 10.1016/j.mce.2011.05.003
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2010

Bogner-Strauss, JG; Prokesch, A; Sanchez-Cabo, F; Rieder, D; Hackl, H; Duszka, K; Krogsdam, A; Di Camillo, B; Walenta, E; Klatzer, A; Lass, A; Pinent, M; Wong, WC; Eisenhaber, F; Trajanoski, Z Reconstruction of gene association network reveals a transmembrane protein required for adipogenesis and targeted by PPARγ.
Cell Mol Life Sci. 2010; 67(23): 4049-4064. Doi: 10.1007/s00018-010-0424-5
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Heitzer, E; Bambach, I; Dandachi, N; Horn, M; Wolf, P PTCH promoter methylation at low level in sporadic basal cell carcinoma analysed by three different approaches.
EXP DERMATOL. 2010; 19(10): 926-928. Doi: 10.1111/j.1600-0625.2010.01120.x [OPEN ACCESS]
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Jamali, S; Salzmann, A; Perroud, N; Ponsole-Lenfant, M; Cillario, J; Roll, P; Roeckel-Trevisiol, N; Crespel, A; Balzar, J; Schlachter, K; Gruber-Sedlmayr, U; Pataraia, E; Baumgartner, C; Zimprich, A; Zimprich, F; Malafosse, A; Szepetowski, P Functional variant in complement C3 gene promoter and genetic susceptibility to temporal lobe epilepsy and febrile seizures.
PLoS One. 2010; 5(9): Doi: 10.1371/journal.pone.0012740 [OPEN ACCESS]
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