Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: MICE, NUDE - , . Treffer: 44

2018

Leithner, K; Triebl, A; Trötzmüller, M; Hinteregger, B; Leko, P; Wieser, BI; Grasmann, G; Bertsch, AL; Züllig, T; Stacher, E; Valli, A; Prassl, R; Olschewski, A; Harris, AL; Köfeler, HC; Olschewski, H; Hrzenjak, A The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells.
Proc Natl Acad Sci U S A. 2018; 115(24):6225-6230 Doi: 10.1073/pnas.1719871115 [OPEN ACCESS]
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Ma, YT; Yang, Y; Cai, P; Sun, DY; Sánchez-Murcia, PA; Zhang, XY; Jia, WQ; Lei, L; Guo, M; Gago, F; Wang, H; Fang, WS A Series of Enthalpically Optimized Docetaxel Analogues Exhibiting Enhanced Antitumor Activity and Water Solubility.
J Nat Prod. 2018; 81(3):524-533 Doi: 10.1021/acs.jnatprod.7b00857
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2017

Bayraktar, R; Pichler, M; Kanlikilicer, P; Ivan, C; Bayraktar, E; Kahraman, N; Aslan, B; Oguztuzun, S; Ulasli, M; Arslan, A; Calin, G; Lopez-Berestein, G; Ozpolat, B MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase.
Oncotarget. 2017; 8(7): 11641-11658. Doi: 10.18632/oncotarget.14264 [OPEN ACCESS]
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Castellani, C; Singer, G; Kaiser, M; Kaiser, T; Huang, J; Sperl, D; Kashofer, K; Fauler, G; Guertl-Lackner, B; Höfler, G; Till, H Neuroblastoma causes alterations of the intestinal microbiome, gut hormones, inflammatory cytokines, and bile acid composition.
Pediatr Blood Cancer. 2017; 64(8): Doi: 10.1002/pbc.26425
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Ding, X; Su, Y; Wang, C; Zhang, F; Chen, K; Wang, Y; Li, M; Wang, W Synergistic Suppression of Tumor Angiogenesis by the Co-delivering of Vascular Endothelial Growth Factor Targeted siRNA and Candesartan Mediated by Functionalized Carbon Nanovectors.
ACS Appl Mater Interfaces. 2017; 9(28):23353-23369 Doi: 10.1021/acsami.7b04971
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Rashed, MH; Kanlikilicer, P; Rodriguez-Aguayo, C; Pichler, M; Bayraktar, R; Bayraktar, E; Ivan, C; Filant, J; Silva, A; Aslan, B; Denizli, M; Mitra, R; Ozpolat, B; Calin, GA; Sood, AK; Abd-Ellah, MF; Helal, GK; Berestein, GL Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs.
Oncotarget. 2017; 8(12):20145-20164 Doi: 10.18632/oncotarget.15525 [OPEN ACCESS]
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Regan, JL; Schumacher, D; Staudte, S; Steffen, A; Haybaeck, J; Keilholz, U; Schweiger, C; Golob-Schwarzl, N; Mumberg, D; Henderson, D; Lehrach, H; Regenbrecht, CRA; Schäfer, R; Lange, M Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells.
Cell Rep. 2017; 21(10):2813-2828 Doi: 10.1016/j.celrep.2017.11.025 [OPEN ACCESS]
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Su, Y; Hu, Y; Wang, Y; Xu, X; Yuan, Y; Li, Y; Wang, Z; Chen, K; Zhang, F; Ding, X; Li, M; Zhou, J; Liu, Y; Wang, W A precision-guided MWNT mediated reawakening the sunk synergy in RAS for anti-angiogenesis lung cancer therapy.
Biomaterials. 2017; 139(28):75-90 Doi: 10.1016/j.biomaterials.2017.05.046
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2016

Arvidsson, Y; Johanson, V; Pfragner, R; Wängberg, B; Nilsson, O Cytotoxic Effects of Valproic Acid on Neuroendocrine Tumour Cells.
Neuroendocrinology. 2016; 103(5):578-591 Doi: 10.1159/000441849
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Kanlikilicer, P; Rashed, MH; Bayraktar, R; Mitra, R; Ivan, C; Aslan, B; Zhang, X; Filant, J; Silva, AM; Rodriguez-Aguayo, C; Bayraktar, E; Pichler, M; Ozpolat, B; Calin, GA; Sood, AK; Lopez-Berestein, G Ubiquitous Release of Exosomal Tumor Suppressor miR-6126 from Ovarian Cancer Cells.
Cancer Res. 2016; 76(24):7194-7207 Doi: 10.1158/0008-5472.CAN-16-0714 [OPEN ACCESS]
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Zhang, F; Li, M; Su, Y; Zhou, J; Wang, W A dual-targeting drug co-delivery system for tumor chemo- and gene combined therapy.
Mater Sci Eng C Mater Biol Appl. 2016; 64(28): 208-218. Doi: 10.1016/j.msec.2016.03.083
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Zhang, F; Wang, X; Xu, X; Li, M; Zhou, J; Wang, W Reconstituted high density lipoprotein mediated targeted co-delivery of HZ08 and paclitaxel enhances the efficacy of paclitaxel in multidrug-resistant MCF-7 breast cancer cells.
Eur J Pharm Sci. 2016; 92(36):11-21 Doi: 10.1016/j.ejps.2016.06.017
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2015

Schwamb, B; Pick, R; Fernández, SB; Völp, K; Heering, J; Dötsch, V; Bösser, S; Jung, J; Beinoraviciute-Kellner, R; Wesely, J; Zörnig, I; Hammerschmidt, M; Nowak, M; Penzel, R; Zatloukal, K; Joos, S; Rieker, RJ; Agaimy, A; Söder, S; Reid-Lombardo, KM; Kendrick, ML; Bardsley, MR; Hayashi, Y; Asuzu, DT; Syed, SA; Ordog, T; Zörnig, M FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors.
Int J Cancer. 2015; 137(6):1318-1329 Doi: 10.1002/ijc.29498 [OPEN ACCESS]
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Stemmer, K; Kotzbeck, P; Zani, F; Bauer, M; Neff, C; Müller, TD; Pfluger, PT; Seeley, RJ; Divanovic, S Thermoneutral housing is a critical factor for immune function and diet-induced obesity in C57BL/6 nude mice.
Int J Obes (Lond). 2015; 39(5): 791-797. Doi: 10.1038/ijo.2014.187 [OPEN ACCESS]
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2014

Ding, X; Wang, W; Wang, Y; Bao, X; Wang, Y; Wang, C; Chen, J; Zhang, F; Zhou, J Versatile reticular polyethylenimine derivative-mediated targeted drug and gene codelivery for tumor therapy.
Mol Pharm. 2014; 11(10):3307-3321 Doi: 10.1021/mp5001263
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Herz, C; Hertrampf, A; Zimmermann, S; Stetter, N; Wagner, M; Kleinhans, C; Erlacher, M; Schüler, J; Platz, S; Rohn, S; Mersch-Sundermann, V; Lamy, E The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.
J Cell Mol Med. 2014; 18(12): 2393-2403. Doi: 10.1111/jcmm.12412 [OPEN ACCESS]
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Liu, L; Salnikov, AV; Bauer, N; Aleksandrowicz, E; Labsch, S; Nwaeburu, C; Mattern, J; Gladkich, J; Schemmer, P; Werner, J; Herr, I Triptolide reverses hypoxia-induced epithelial-mesenchymal transition and stem-like features in pancreatic cancer by NF-κB downregulation.
Int J Cancer. 2014; 134(10):2489-2503 Doi: 10.1002/ijc.28583 [OPEN ACCESS]
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2013

Kollmann, K; Heller, G; Schneckenleithner, C; Warsch, W; Scheicher, R; Ott, RG; Schäfer, M; Fajmann, S; Schlederer, M; Schiefer, AI; Reichart, U; Mayerhofer, M; Hoeller, C; Zöchbauer-Müller, S; Kerjaschki, D; Bock, C; Kenner, L; Hoefler, G; Freissmuth, M; Green, AR; Moriggl, R; Busslinger, M; Malumbres, M; Sexl, V A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis.
Cancer Cell. 2013; 24(2):167-181 Doi: 10.1016/j.ccr.2013.07.012 [OPEN ACCESS]
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Rangger, C; Helbok, A; Sosabowski, J; Kremser, C; Koehler, G; Prassl, R; Andreae, F; Virgolini, IJ; von Guggenberg, E; Decristoforo, C Tumor targeting and imaging with dual-peptide conjugated multifunctional liposomal nanoparticles.
Int J Nanomedicine. 2013; 8(6):4659-4671 Doi: 10.2147/IJN.S51927 [OPEN ACCESS]
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2012

Helbok, A; Rangger, C; von Guggenberg, E; Saba-Lepek, M; Radolf, T; Thurner, G; Andreae, F; Prassl, R; Decristoforo, C Targeting properties of peptide-modified radiolabeled liposomal nanoparticles
NANOMED-NANOTECHNOL. 2012; 8(1): 112-118. Doi: 10.1016/j.nano.2011.04.012
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Kawaguchi, R; Nunomura, S; Umehara, N; Nikaido, T; Huppertz, B; Tanaka, T; Ra, C Multiple injections of anti-mouse β2glycoprotein 1 antibody induce FcRγ-dependent fetal growth restriction (FGR) in mice.
Placenta. 2012; 33(7):540-547 Doi: 10.1016/j.placenta.2012.03.010
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Liu, SJ; Tetzlaff, MT; Liu, AH; Liegl-Atzwanger, B; Guo, J; Xu, XW; Loss of microRNA-205 expression is associated with melanoma progression.
Lab Invest. 2012; 92(7):1084-1096 Doi: 10.1038/labinvest.2012.62 [OPEN ACCESS]
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Rangger, C; Helbok, A; von Guggenberg, E; Sosabowski, J; Radolf, T; Prassl, R; Andreae, F; Thurner, GC; Haubner, R; Decristoforo, C Influence of PEGylation and RGD loading on the targeting properties of radiolabeled liposomal nanoparticles.
Int J Nanomedicine. 2012; 7(4):5889-5900 Doi: 10.2147/IJN.S36847 [OPEN ACCESS]
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Rausch, V; Liu, L; Apel, A; Rettig, T; Gladkich, J; Labsch, S; Kallifatidis, G; Kaczorowski, A; Groth, A; Gross, W; Gebhard, MM; Schemmer, P; Werner, J; Salnikov, AV; Zentgraf, H; Büchler, MW; Herr, I Autophagy mediates survival of pancreatic tumour-initiating cells in a hypoxic microenvironment.
J Pathol. 2012; 227(3):325-335 Doi: 10.1002/path.3994
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2010

Hrzenjak, A; Moinfar, F; Kremser, ML; Strohmeier, B; Petru, E; Zatloukal, K; Denk, H Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo.
Mol Cancer. 2010; 9(10): 49-49. Doi: 10.1186/1476-4598-9-49 [OPEN ACCESS]
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Krejsgaard, T; Kopp, K; Ralfkiaer, E; Willumsgaard, AE; Eriksen, KW; Labuda, T; Rasmussen, S; Mathiesen, AM; Geisler, C; Lauenborg, B; Becker, JC; Zhang, Q; Wasik, MA; Odum, N; Woetmann, A A novel xenograft model of cutaneous T-cell lymphoma.
Exp Dermatol. 2010; 19(12):1096-1102 Doi: 10.1111/j.1600-0625.2010.01138.x
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Rausch, V; Liu, L; Kallifatidis, G; Baumann, B; Mattern, J; Gladkich, J; Wirth, T; Schemmer, P; Büchler, MW; Zöller, M; Salnikov, AV; Herr, I Synergistic activity of sorafenib and sulforaphane abolishes pancreatic cancer stem cell characteristics.
Cancer Res. 2010; 70(12):5004-5013 Doi: 10.1158/0008-5472.CAN-10-0066 [OPEN ACCESS]
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2009

Brader, P; Kelly, KJ; Chen, N; Yu, YA; Zhang, Q; Zanzonico, P; Burnazi, EM; Ghani, RE; Serganova, I; Hricak, H; Szalay, AA; Fong, Y; Blasberg, RG Imaging a Genetically Engineered Oncolytic Vaccinia Virus (GLV-1h99) Using a Human Norepinephrine Transporter Reporter Gene.
Clin Cancer Res. 2009; 15(11):3791-3801 Doi: 10.1158/1078-0432.CCR-08-3236 [OPEN ACCESS]
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Gebeshuber, CA; Zatloukal, K; Martinez, J miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis.
EMBO Rep. 2009; 10(4): 400-405. Doi: 10.1038/embor.2009.9 [OPEN ACCESS]
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Kallifatidis, G; Rausch, V; Baumann, B; Apel, A; Beckermann, BM; Groth, A; Mattern, J; Li, Z; Kolb, A; Moldenhauer, G; Altevogt, P; Wirth, T; Werner, J; Schemmer, P; Büchler, MW; Salnikov, AV; Herr, I Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling.
Gut. 2009; 58(7):949-963 Doi: 10.1136/gut.2008.149039
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Kashofer, K; Tschernatsch, MM; Mischinger, HJ; Iberer, F; Zatloukal, K The disease relevance of human hepatocellular xenograft models: molecular characterization and review of the literature.
Cancer Lett. 2009; 286(1):121-128 Doi: 10.1016/j.canlet.2008.11.011
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Mönckedieck, V; Sannecke, C; Husen, B; Kumbartski, M; Kimmig, R; Tötsch, M; Winterhager, E; Grümmer, R Progestins inhibit expression of MMPs and of angiogenic factors in human ectopic endometrial lesions in a mouse model.
Mol Hum Reprod. 2009; 15(10):633-643 Doi: 10.1093/molehr/gap063 [OPEN ACCESS]
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Reinisch, A; Hofmann, NA; Obenauf, AC; Kashofer, K; Rohde, E; Schallmoser, K; Flicker, K; Lanzer, G; Linkesch, W; Speicher, MR; Strunk, D Humanized large-scale expanded endothelial colony-forming cells function in vitro and in vivo.
Blood. 2009; 113(26): 6716-6725. Doi: 10.1182/blood-2008-09-181362 [OPEN ACCESS]
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Silberhumer, GR; Zakian, K; Malhotra, S; Brader, P; Gönen, M; Koutcher, J; Fong, Y Relationship between 31P metabolites and oncolytic viral therapy sensitivity in human colorectal cancer xenografts.
Br J Surg. 2009; 96(7):809-816 Doi: 10.1002/bjs.6604
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Thalheimer, A; Otto, C; Bueter, M; Illert, B; Gattenlohner, S; Gasser, M; Fein, M; Germer, CT; Waaga-Gasser, AM Tumor cell dissemination in a human colon cancer animal model: orthotopic implantation or intraportal injection?
Eur Surg Res. 2009; 42(3):195-200 Doi: 10.1159/000205825
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Thalheimer, A; Otto, C; Bueter, M; Illert, B; Gattenlohner, S; Gasser, M; Meyer, D; Fein, M; Germer, CT; Waaga-Gasser, AM The intraportal injection model: a practical animal model for hepatic metastases and tumor cell dissemination in human colon cancer.
BMC Cancer. 2009; 9(2):29-29 Doi: 10.1186/1471-2407-9-29 [OPEN ACCESS]
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Yu, Z; Li, S; Brader, P; Chen, N; Yu, YA; Zhang, Q; Szalay, AA; Fong, Y; Wong, RJ Oncolytic vaccinia therapy of squamous cell carcinoma.
Mol Cancer. 2009; 8(4): 45-45. Doi: 10.1186/1476-4598-8-45 [OPEN ACCESS]
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2008

Hui, L; Zatloukal, K; Scheuch, H; Stepniak, E; Wagner, EF Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation.
J Clin Invest. 2008; 118(12): 3943-3953. Doi: 10.1172/JCI37156 [OPEN ACCESS]
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Kelly, K; Brader, P; Rein, A; Shah, JP; Wong, RJ; Fong, Y; Gil, Z Attenuated multimutated herpes simplex virus-1 effectively treats prostate carcinomas with neural invasion while preserving nerve function.
FASEB J. 2008; 22(6):1839-1848 Doi: 10.1096/fj.07-097808 [OPEN ACCESS]
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Kelly, KJ; Woo, Y; Brader, P; Yu, Z; Riedl, C; Lin, SF; Chen, N; Yu, YA; Rusch, VW; Szalay, AA; Fong, Y Novel oncolytic agent GLV-1h68 is effective against malignant pleural mesothelioma.
Hum Gene Ther. 2008; 19(8):774-782 Doi: 10.1089/hum.2008.036 [OPEN ACCESS]
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Lin, SF; Price, DL; Chen, CH; Brader, P; Li, S; Gonzalez, L; Zhang, Q; Yu, YA; Chen, N; Szalay, AA; Fong, Y; Wong, RJ Oncolytic vaccinia virotherapy of anaplastic thyroid cancer in vivo.
J Clin Endocrinol Metab. 2008; 93(11):4403-4407 Doi: 10.1210/jc.2008-0316 [OPEN ACCESS]
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2007

Wolbank, S; Peterbauer, A; Wassermann, E; Hennerbichler, S; Voglauer, R; van Griensven, M; Duba, HC; Gabriel, C; Redl, H Labelling of human adipose-derived stem cells for non-invasive in vivo cell tracking.
Cell Tissue Bank. 2007; 8(3): 163-177. Doi: 10.1007/s10561-006-9027-7
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2006

Cam, H; Griesmann, H; Beitzinger, M; Hofmann, L; Beinoraviciute-Kellner, R; Sauer, M; Huttinger-Kirchhof, N; Oswald, C; Friedl, P; Gattenlohner, S; Burek, C; Rosenwald, A; Stiewe, T p53 family members in myogenic differentiation and rhabdomyosarcoma development.
Cancer Cell. 2006; 10(4):281-293 Doi: 10.1016/j.ccr.2006.08.024 [OPEN ACCESS]
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Thalheimer, A; Illert, B; Bueter, M; Gattenlohner, S; Stehle, D; Gasser, M; Thiede, A; Waaga-Gasser, AM; Meyer, D Feasibility and limits of an orthotopic human colon cancer model in nude mice.
Comp Med. 2006; 56(2):105-109
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