Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: LIVER - METABOLISM , . Treffer: 249

2018

Krones, E; Pollheimer, MJ; Rosenkranz, AR; Fickert, P Cholemic nephropathy - Historical notes and novel perspectives.
Biochim Biophys Acta Mol Basis Dis. 2018; 1864(4 Pt B):1356-1366 [OPEN ACCESS]
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Ramirez, T; Strigun, A; Verlohner, A; Huener, HA; Peter, E; Herold, M; Bordag, N; Mellert, W; Walk, T; Spitzer, M; Jiang, X; Sperber, S; Hofmann, T; Hartung, T; Kamp, H; van Ravenzwaay, B Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells.
Arch Toxicol. 2018; 92(2): 893-906. [OPEN ACCESS]
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Tang, Y; Blomenkamp, KS; Fickert, P; Trauner, M; Teckman, JH NorUDCA promotes degradation of α1-antitrypsin mutant Z protein by inducing autophagy through AMPK/ULK1 pathway.
PLoS One. 2018; 13(8):e0200897-e0200897 [OPEN ACCESS]
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2017

Aigelsreiter, A; Neumann, J; Pichler, M; Halasz, J; Zatloukal, K; Berghold, A; Douschan, P; Rainer, F; Stauber, R; Haybaeck, J; Denk, H; Lackner, C Hepatocellular carcinomas with intracellular hyaline bodies have a poor prognosis.
Liver Int. 2017; 37(4):600-610
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Fuchs, CD; Claudel, T; Scharnagl, H; Stojakovic, T; Trauner, M FXR controls CHOP expression in steatohepatitis.
FEBS Lett. 2017; 591(20):3360-3368 [OPEN ACCESS]
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Gong, JY; Setchell, KDR; Zhao, J; Zhang, W; Wolfe, B; Lu, Y; Lackner, K; Knisely, AS; Wang, NL; Hao, CZ; Zhang, MH; Wang, JS Severe Neonatal Cholestasis in Cerebrotendinous Xanthomatosis: Genetics, Immunostaining, Mass Spectrometry.
J Pediatr Gastroenterol Nutr. 2017; 65(5):561-568
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Katanić, J; Matić, S; Pferschy-Wenzig, EM; Kretschmer, N; Boroja, T; Mihailović, V; Stanković, V; Stanković, N; Mladenović, M; Stanić, S; Mihailović, M; Bauer, R Filipendula ulmaria extracts attenuate cisplatin-induced liver and kidney oxidative stress in rats: In vivo investigation and LC-MS analysis.
Food Chem Toxicol. 2017; 99(2):86-102
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Lindquist, C; Bjørndal, B; Rossmann, CR; Tusubira, D; Svardal, A; Røsland, GV; Tronstad, KJ; Hallström, S; Berge, RK Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in rats.
J Lipid Res. 2017; 58(7):1362-1373 [OPEN ACCESS]
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Melvin, AJ; Warshaw, M; Compagnucci, A; Saidi, Y; Harrison, L; Turkova, A; Tudor-Williams, G; Tudor-Williams, G Hepatic, Renal, Hematologic, and Inflammatory Markers in HIV-Infected Children on Long-term Suppressive Antiretroviral Therapy.
J Pediatric Infect Dis Soc. 2017; 6(3):e109-e115-e109-e115 [OPEN ACCESS]
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Mueller, KM; Hartmann, K; Kaltenecker, D; Vettorazzi, S; Bauer, M; Mauser, L; Amann, S; Jall, S; Fischer, K; Esterbauer, H; Müller, TD; Tschöp, MH; Magnes, C; Haybaeck, J; Scherer, T; Bordag, N; Tuckermann, JP; Moriggl, R Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition.
Diabetes. 2017; 66(2):272-286 [OPEN ACCESS]
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Nelson, ME; Lahiri, S; Chow, JD; Byrne, FL; Hargett, SR; Breen, DS; Olzomer, EM; Wu, LE; Cooney, GJ; Turner, N; James, DE; Slack-Davis, JK; Lackner, C; Caldwell, SH; Hoehn, KL Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival.
Nat Commun. 2017; 8(6):14689-14689 [OPEN ACCESS]
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Prokesch, A; Graef, FA; Madl, T; Kahlhofer, J; Heidenreich, S; Schumann, A; Moyschewitz, E; Pristoynik, P; Blaschitz, A; Knauer, M; Muenzner, M; Bogner-Strauss, JG; Dohr, G; Schulz, TJ; Schupp, M Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.
FASEB J. 2017; 31(2):732-742 [OPEN ACCESS]
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Qiu, YL; Gong, JY; Feng, JY; Wang, RX; Han, J; Liu, T; Lu, Y; Li, LT; Zhang, MH; Sheps, JA; Wang, NL; Yan, YY; Li, JQ; Chen, L; Borchers, CH; Sipos, B; Knisely, AS; Ling, V; Xing, QH; Wang, JS Defects in myosin VB are associated with a spectrum of previously undiagnosed low γ-glutamyltransferase cholestasis.
Hepatology. 2017; 65(5):1655-1669 [OPEN ACCESS]
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Vahdati Hassani, F; Mehri, S; Abnous, K; Birner-Gruenberger, R; Hosseinzadeh, H Protective effect of crocin on BPA-induced liver toxicity in rats through inhibition of oxidative stress and downregulation of MAPK and MAPKAP signaling pathway and miRNA-122 expression.
Food Chem Toxicol. 2017; 107(Pt A):395-405
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Vujic, N; Korbelius, M; Leopold, C; Duta-Mare, M; Rainer, S; Schlager, S; Goeritzer, M; Kolb, D; Eichmann, TO; Diwoky, C; Zimmer, A; Zimmermann, R; Lass, A; Radovic, B; Kratky, D Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice.
Oncotarget. 2017; 8(20):33122-33136 [OPEN ACCESS]
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2016

Bartuzi, P; Billadeau, DD; Favier, R; Rong, S; Dekker, D; Fedoseienko, A; Fieten, H; Wijers, M; Levels, JH; Huijkman, N; Kloosterhuis, N; van der Molen, H; Brufau, G; Groen, AK; Elliott, AM; Kuivenhoven, JA; Plecko, B; Grangl, G; McGaughran, J; Horton, JD; Burstein, E; Hofker, MH; van de Sluis, B CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.
Nat Commun. 2016; 7(5):10961-10961 [OPEN ACCESS]
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Fengler, VH; Macheiner, T; Kessler, SM; Czepukojc, B; Gemperlein, K; Müller, R; Kiemer, AK; Magnes, C; Haybaeck, J; Lackner, C; Sargsyan, K Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease.
PLoS One. 2016; 11(5):e0155163-e0155163 [OPEN ACCESS]
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Hartmann, P; Seebauer, CT; Mazagova, M; Horvath, A; Wang, L; Llorente, C; Varki, NM; Brandl, K; Ho, SB; Schnabl, B Deficiency of intestinal mucin-2 protects mice from diet-induced fatty liver disease and obesity.
Am J Physiol Gastrointest Liver Physiol. 2016; 310(5):G310-G322 [OPEN ACCESS]
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Kawala, MA; Bohndorf, M; Graffmann, N; Wruck, W; Zatloukal, K; Adjaye, J Characterization of dermal fibroblast-derived iPSCs from a patient with high grade steatosis.
Stem Cell Res. 2016; 17(3):568-571 [OPEN ACCESS]
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Miller, HC; Frampton, AE; Malczewska, A; Ottaviani, S; Stronach, EA; Flora, R; Kaemmerer, D; Schwach, G; Pfragner, R; Faiz, O; Kos-Kudła, B; Hanna, GB; Stebbing, J; Castellano, L; Frilling, A MicroRNAs associated with small bowel neuroendocrine tumours and their metastases.
Endocr Relat Cancer. 2016; 23(9):711-726 [OPEN ACCESS]
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Radović, B; Vujić, N; Leopold, C; Schlager, S; Goeritzer, M; Patankar, JV; Korbelius, M; Kolb, D; Reindl, J; Wegscheider, M; Tomin, T; Birner-Gruenberger, R; Schittmayer, M; Groschner, L; Magnes, C; Diwoky, C; Frank, S; Steyrer, E; Du, H; Graier, WF; Madl, T; Kratky, D Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice.
Diabetologia. 2016; 59(8):1743-1752 [OPEN ACCESS]
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Sachdev, V; Leopold, C; Bauer, R; Patankar, JV; Iqbal, J; Obrowsky, S; Boverhof, R; Doktorova, M; Scheicher, B; Goeritzer, M; Kolb, D; Turnbull, AV; Zimmer, A; Hoefler, G; Hussain, MM; Groen, AK; Kratky, D Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.
Biochim Biophys Acta. 2016; 1861(9 Pt A):1132-1141 [OPEN ACCESS]
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Scharinger, B; Messner, B; Türkcan, A; Schuster, D; Vuorinen, A; Pitterl, F; Heinz, K; Arnhard, K; Laufer, G; Grimm, M; Stuppner, H; Oberacher, H; Eller, P; Ritsch, A; Bernhard, D Leoligin, the major lignan from Edelweiss, inhibits 3-hydroxy-3-methyl-glutaryl-CoA reductase and reduces cholesterol levels in ApoE-/- mice.
J Mol Cell Cardiol. 2016; 99(7):35-46 [OPEN ACCESS]
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Themanns, M; Mueller, KM; Kessler, SM; Golob-Schwarzl, N; Mohr, T; Kaltenecker, D; Bourgeais, J; Paier-Pourani, J; Friedbichler, K; Schneller, D; Schlederer, M; Zebedin-Brandl, E; Terracciano, LM; Han, X; Kenner, L; Wagner, KU; Mikulits, W; Kozlov, AV; Heim, MH; Gouilleux, F; Haybaeck, J; Moriggl, R Hepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice.
Sci Rep. 2016; 6(4):34719-34719 [OPEN ACCESS]
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Trieb, M; Horvath, A; Birner-Gruenberger, R; Spindelboeck, W; Stadlbauer, V; Taschler, U; Curcic, S; Stauber, RE; Holzer, M; Pasterk, L; Heinemann, A; Marsche, G Liver disease alters high-density lipoprotein composition, metabolism and function.
Biochim Biophys Acta. 2016; 1861(7):630-638 [OPEN ACCESS]
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Trierweiler, C; Hockenjos, B; Zatloukal, K; Thimme, R; Blum, HE; Wagner, EF; Hasselblatt, P The transcription factor c-JUN/AP-1 promotes HBV-related liver tumorigenesis in mice.
Cell Death Differ. 2016; 23(4):576-582 [OPEN ACCESS]
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Vinod, M; Patankar, JV; Sachdev, V; Frank, S; Graier, WF; Kratky, D; Kostner, GM MiR-206 is expressed in pancreatic islets and regulates glucokinase activity.
Am J Physiol Endocrinol Metab. 2016; 311(1):E175-E185 [OPEN ACCESS]
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Wagner, M; Choi, S; Panzitt, K; Mamrosh, JL; Lee, JM; Zaufel, A; Xiao, R; Wooton-Kee, R; Ståhlman, M; Newgard, CB; Borén, J; Moore, DD Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism.
Hepatology. 2016; 63(1):95-106 [OPEN ACCESS]
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Yang, H; Ni, HM; Guo, F; Ding, Y; Shi, YH; Lahiri, P; Fröhlich, LF; Rülicke, T; Smole, C; Schmidt, VC; Zatloukal, K; Cui, Y; Komatsu, M; Fan, J; Ding, WX Sequestosome 1/p62 Protein Is Associated with Autophagic Removal of Excess Hepatic Endoplasmic Reticulum in Mice.
J Biol Chem. 2016; 291(36):18663-18674 [OPEN ACCESS]
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2015

Abuja, PM; Ehrhart, F; Schoen, U; Schmidt, T; Stracke, F; Dallmann, G; Friedrich, T; Zimmermann, H; Zatloukal, K Alterations in Human Liver Metabolome during Prolonged Cryostorage.
J Proteome Res. 2015; 14(7):2758-2768
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Argo, CK; Patrie, JT; Lackner, C; Henry, TD; de Lange, EE; Weltman, AL; Shah, NL; Al-Osaimi, AM; Pramoonjago, P; Jayakumar, S; Binder, LP; Simmons-Egolf, WD; Burks, SG; Bao, Y; Taylor, AG; Rodriguez, J; Caldwell, SH Effects of n-3 fish oil on metabolic and histological parameters in NASH: a double-blind, randomized, placebo-controlled trial.
J Hepatol. 2015; 62(1):190-197 [OPEN ACCESS]
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Chen, Y; Guldiken, N; Spurny, M; Mohammed, HH; Haybaeck, J; Pollheimer, MJ; Fickert, P; Gassler, N; Jeon, MK; Trautwein, C; Strnad, P Loss of keratin 19 favours the development of cholestatic liver disease through decreased ductular reaction.
J Pathol. 2015; 237(3):343-354
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Chmelík, M; Valkovič, L; Wolf, P; Bogner, W; Gajdošík, M; Halilbasic, E; Gruber, S; Trauner, M; Krebs, M; Trattnig, S; Krššák, M Phosphatidylcholine contributes to in vivo (31)P MRS signal from the human liver.
Eur Radiol. 2015; 25(7):2059-2066
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Dražić, T; Sachdev, V; Leopold, C; Patankar, JV; Malnar, M; Hećimović, S; Levak-Frank, S; Habuš, I; Kratky, D Synthesis and evaluation of novel amide amino-β-lactam derivatives as cholesterol absorption inhibitors.
Bioorg Med Chem. 2015; 23(10):2353-2359 [OPEN ACCESS]
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Fritsch, M; Koliaki, C; Livingstone, R; Phielix, E; Bierwagen, A; Meisinger, M; Jelenik, T; Strassburger, K; Zimmermann, S; Brockmann, K; Wolff, C; Hwang, JH; Szendroedi, J; Roden, M Time course of postprandial hepatic phosphorus metabolites in lean, obese, and type 2 diabetes patients.
Am J Clin Nutr. 2015; 102(5):1051-1058
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Grangl, G; Zöhrer, E; Köstenberger, M; Jud, A; Fauler, G; Scharnagl, H; Stojakovic, T; Marterer, R; Gamillscheg, A; Jahnel, J Serum Bile Acids in Repaired Tetralogy of Fallot: A Marker for Liver and Heart?
PLoS One. 2015; 10(12):e0144745-e0144745 [OPEN ACCESS]
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Healy, ME; Chow, JD; Byrne, FL; Breen, DS; Leitinger, N; Li, C; Lackner, C; Caldwell, SH; Hoehn, KL Dietary effects on liver tumor burden in mice treated with the hepatocellular carcinogen diethylnitrosamine.
J Hepatol. 2015; 62(3):599-606 [OPEN ACCESS]
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Jaeger, D; Schoiswohl, G; Hofer, P; Schreiber, R; Schweiger, M; Eichmann, TO; Pollak, NM; Poecher, N; Grabner, GF; Zierler, KA; Eder, S; Kolb, D; Radner, FP; Preiss-Landl, K; Lass, A; Zechner, R; Kershaw, EE; Haemmerle, G Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids.
J Hepatol. 2015; 63(2):437-445 [OPEN ACCESS]
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Melchardt, T; Troppan, K; Weiss, L; Hufnagl, C; Neureiter, D; Tränkenschuh, W; Schlick, K; Huemer, F; Deutsch, A; Neumeister, P; Greil, R; Pichler, M; Egle, A Independent Prognostic Value of Serum Markers in Diffuse Large B-Cell Lymphoma in the Era of the NCCN-IPI.
J Natl Compr Canc Netw. 2015; 13(12):1501-1508
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Mueller, M; Thorell, A; Claudel, T; Jha, P; Koefeler, H; Lackner, C; Hoesel, B; Fauler, G; Stojakovic, T; Einarsson, C; Marschall, HU; Trauner, M Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity.
J Hepatol. 2015; 62(6):1398-1404 [OPEN ACCESS]
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Neve, EP; Köfeler, H; Hendriks, DF; Nordling, Å; Gogvadze, V; Mkrtchian, S; Näslund, E; Ingelman-Sundberg, M Expression and Function of mARC: Roles in Lipogenesis and Metabolic Activation of Ximelagatran.
PLoS One. 2015; 10(9):e0138487-e0138487 [OPEN ACCESS]
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Stättermayer, AF; Traussnigg, S; Dienes, HP; Aigner, E; Stauber, R; Lackner, K; Hofer, H; Stift, J; Wrba, F; Stadlmayr, A; Datz, C; Strasser, M; Maieron, A; Trauner, M; Ferenci, P Hepatic steatosis in Wilson disease--Role of copper and PNPLA3 mutations.
J Hepatol. 2015; 63(1):156-163
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Stemmer, K; Zani, F; Habegger, KM; Neff, C; Kotzbeck, P; Bauer, M; Yalamanchilli, S; Azad, A; Lehti, M; Martins, PJ; Müller, TD; Pfluger, PT; Seeley, RJ FGF21 is not required for glucose homeostasis, ketosis or tumour suppression associated with ketogenic diets in mice.
Diabetologia. 2015; 58(10):2414-2423 [OPEN ACCESS]
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Szabo, S; Wögenstein, KL; Österreicher, CH; Guldiken, N; Chen, Y; Doler, C; Wiche, G; Boor, P; Haybaeck, J; Strnad, P; Fuchs, P Epiplakin attenuates experimental mouse liver injury by chaperoning keratin reorganization.
J Hepatol. 2015; 62(6):1357-1366 [OPEN ACCESS]
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Wooton-Kee, CR; Jain, AK; Wagner, M; Grusak, MA; Finegold, MJ; Lutsenko, S; Moore, DD Elevated copper impairs hepatic nuclear receptor function in Wilson's disease.
J Clin Invest. 2015; 125(9):3449-3460 [OPEN ACCESS]
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Wruck, W; Kashofer, K; Rehman, S; Daskalaki, A; Berg, D; Gralka, E; Jozefczuk, J; Drews, K; Pandey, V; Regenbrecht, C; Wierling, C; Turano, P; Korf, U; Zatloukal, K; Lehrach, H; Westerhoff, HV; Adjaye, J Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes.
Sci Data. 2015; 2(S 01):150068-150068 [OPEN ACCESS]
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2014

Bettermann, K; Hohensee, T; Haybaeck, J Steatosis and steatohepatitis: complex disorders.
Int J Mol Sci. 2014; 15(6):9924-9944 [OPEN ACCESS]
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Demetz, E; Schroll, A; Auer, K; Heim, C; Patsch, JR; Eller, P; Theurl, M; Theurl, I; Theurl, M; Seifert, M; Lener, D; Stanzl, U; Haschka, D; Asshoff, M; Dichtl, S; Nairz, M; Huber, E; Stadlinger, M; Moschen, AR; Li, X; Pallweber, P; Scharnagl, H; Stojakovic, T; März, W; Kleber, ME; Garlaschelli, K; Uboldi, P; Catapano, AL; Stellaard, F; Rudling, M; Kuba, K; Imai, Y; Arita, M; Schuetz, JD; Pramstaller, PP; Tietge, UJF; Trauner, M; Norata, GD; Claudel, T; Hicks, AA; Weiss, G; Tancevski, I The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism.
Cell Metab. 2014; 20(5):787-798 [OPEN ACCESS]
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Fuchs, CD; Claudel, T; Trauner, M Role of metabolic lipases and lipolytic metabolites in the pathogenesis of NAFLD.
Trends Endocrinol Metab. 2014; 25(11):576-585
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Herz, C; Hertrampf, A; Zimmermann, S; Stetter, N; Wagner, M; Kleinhans, C; Erlacher, M; Schüler, J; Platz, S; Rohn, S; Mersch-Sundermann, V; Lamy, E The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.
J Cell Mol Med. 2014; 18(12):2393-2403 [OPEN ACCESS]
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