Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Publikationen
Suchbegriffe: HISTONES - METABOLISM , . Treffer: 21
2019
Geißler, D; Wegmann, M; Jochum, T; Somma, V; Sowa, M; Scholz, J; Fröhlich, E; Hoffmann, K; Niehaus, J; Roggenbuck, D; Resch-Genger, U
An automatable platform for genotoxicity testing of nanomaterials based on the fluorometric γ-H2AX assay reveals no genotoxicity of properly surface-shielded cadmium-based quantum dots.
Nanoscale. 2019; 11(28):13458-13468
Doi: 10.1039/c9nr01021a
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2017
Boege, Y; Malehmir, M; Healy, ME; Bettermann, K; Lorentzen, A; Vucur, M; Ahuja, AK; Böhm, F; Mertens, JC; Shimizu, Y; Frick, L; Remouchamps, C; Mutreja, K; Kähne, T; Sundaravinayagam, D; Wolf, MJ; Rehrauer, H; Koppe, C; Speicher, T; Padrissa-Altés, S; Maire, R; Schattenberg, JM; Jeong, JS; Liu, L; Zwirner, S; Boger, R; Hüser, N; Davis, RJ; Müllhaupt, B; Moch, H; Schulze-Bergkamen, H; Clavien, PA; Werner, S; Borsig, L; Luther, SA; Jost, PJ; Weinlich, R; Unger, K; Behrens, A; Hillert, L; Dillon, C; Di Virgilio, M; Wallach, D; Dejardin, E; Zender, L; Naumann, M; Walczak, H; Green, DR; Lopes, M; Lavrik, I; Luedde, T; Heikenwalder, M; Weber, A
A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development.
Cancer Cell. 2017; 32(3):342-359
Doi: 10.1016/j.ccell.2017.08.010
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Fröhlich, E
Role of omics techniques in the toxicity testing of nanoparticles.
J Nanobiotechnology. 2017; 15(1):84-84
Doi: 10.1186/s12951-017-0320-3
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Wygrecka, M; Kosanovic, D; Wujak, L; Reppe, K; Henneke, I; Frey, H; Didiasova, M; Kwapiszewska, G; Marsh, LM; Baal, N; Hackstein, H; Zakrzewicz, D; Müller-Redetzky, HC; de Maat, S; Maas, C; Nolte, MW; Panousis, C; Schermuly, RT; Seeger, W; Witzenrath, M; Schaefer, L; Markart, P
Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury.
Am J Respir Crit Care Med. 2017; 196(2):186-199
Doi: 10.1164/rccm.201604-0712OC
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2015
Fischer, C; Leithner, K; Wohlkoenig, C; Quehenberger, F; Bertsch, A; Olschewski, A; Olschewski, H; Hrzenjak, A
Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1α destabilization.
Mol Cancer. 2015; 14(8):4-4
Doi: 10.1186/1476-4598-14-4
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Lin, AP; Abbas, S; Kim, SW; Ortega, M; Bouamar, H; Escobedo, Y; Varadarajan, P; Qin, Y; Sudderth, J; Schulz, E; Deutsch, A; Mohan, S; Ulz, P; Neumeister, P; Rakheja, D; Gao, X; Hinck, A; Weintraub, ST; DeBerardinis, RJ; Sill, H; Dahia, PL; Aguiar, RC
D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2.
Nat Commun. 2015; 6(7):7768-7768
Doi: 10.1038/ncomms8768
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Mayr, C; Neureiter, D; Wagner, A; Pichler, M; Kiesslich, T
The role of polycomb repressive complexes in biliary tract cancer.
Expert Opin Ther Targets. 2015; 19(3):363-375
Doi: 10.1517/14728222.2014.986460
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Mrakovcic, M; Meindl, C; Leitinger, G; Roblegg, E; Fröhlich, E
Carboxylated short single-walled carbon nanotubes but not plain and multi-walled short carbon nanotubes show in vitro genotoxicity.
Toxicol Sci. 2015; 144(1):114-127
Doi: 10.1093/toxsci/kfu260
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Wiesner, T; Lee, W; Obenauf, AC; Ran, L; Murali, R; Zhang, QF; Wong, EW; Hu, W; Scott, SN; Shah, RH; Landa, I; Button, J; Lailler, N; Sboner, A; Gao, D; Murphy, DA; Cao, Z; Shukla, S; Hollmann, TJ; Wang, L; Borsu, L; Merghoub, T; Schwartz, GK; Postow, MA; Ariyan, CE; Fagin, JA; Zheng, D; Ladanyi, M; Busam, KJ; Berger, MF; Chen, Y; Chi, P
Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.
Nature. 2015; 526(7573):453-457
Doi: 10.1038/nature15258
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2014
Eisenberg, T; Schroeder, S; Andryushkova, A; Pendl, T; Küttner, V; Bhukel, A; Mariño, G; Pietrocola, F; Harger, A; Zimmermann, A; Moustafa, T; Sprenger, A; Jany, E; Büttner, S; Carmona-Gutierrez, D; Ruckenstuhl, C; Ring, J; Reichelt, W; Schimmel, K; Leeb, T; Moser, C; Schatz, S; Kamolz, LP; Magnes, C; Sinner, F; Sedej, S; Fröhlich, KU; Juhasz, G; Pieber, TR; Dengjel, J; Sigrist, SJ; Kroemer, G; Madeo, F
Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan.
Cell Metab. 2014; 19(3):431-444
Doi: 10.1016/j.cmet.2014.02.010
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Lee, W; Teckie, S; Wiesner, T; Ran, L; Prieto Granada, CN; Lin, M; Zhu, S; Cao, Z; Liang, Y; Sboner, A; Tap, WD; Fletcher, JA; Huberman, KH; Qin, LX; Viale, A; Singer, S; Zheng, D; Berger, MF; Chen, Y; Antonescu, CR; Chi, P
PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors.
Nat Genet. 2014; 46(11): 1227-1232.
Doi: 10.1038/ng.3095
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2013
Bysani, M; Wallerman, O; Bornelöv, S; Zatloukal, K; Komorowski, J; Wadelius, C
ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer.
BMC Med Genomics. 2013; 6(11):50-50
Doi: 10.1186/1755-8794-6-50
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Shirsath, N; Rathos, M; Chaudhari, U; Sivaramakrishnan, H; Joshi, K
Potentiation of anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the cyclin-dependent kinase inhibitor P276-00 in human non-small-cell lung cancer cell lines.
Lung Cancer. 2013; 82(2):214-221
Doi: 10.1016/j.lungcan.2013.08.010
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2012
Agrawal-Singh, S; Isken, F; Agelopoulos, K; Klein, HU; Thoennissen, NH; Koehler, G; Hascher, A; Bäumer, N; Berdel, WE; Thiede, C; Ehninger, G; Becker, A; Schlenke, P; Wang, Y; McClelland, M; Krug, U; Koschmieder, S; Büchner, T; Yu, DY; Singh, SV; Hansen, K; Serve, H; Dugas, M; Müller-Tidow, C
Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene.
Blood. 2012; 119(10): 2346-2357.
Doi: 10.1182/blood-2011-06-358705
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2011
Carmona-Gutiérrez, D; Bauer, MA; Ring, J; Knauer, H; Eisenberg, T; Büttner, S; Ruckenstuhl, C; Reisenbichler, A; Magnes, C; Rechberger, GN; Birner-Gruenberger, R; Jungwirth, H; Fröhlich, KU; Sinner, F; Kroemer, G; Madeo, F
The propeptide of yeast cathepsin D inhibits programmed necrosis.
Cell Death Dis. 2011; 2(16):e161-e161
Doi: 10.1038/cddis.2011.43
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2010
Müller-Tidow, C; Klein, HU; Hascher, A; Isken, F; Tickenbrock, L; Thoennissen, N; Agrawal-Singh, S; Tschanter, P; Disselhoff, C; Wang, Y; Becker, A; Thiede, C; Ehninger, G; zur Stadt, U; Koschmieder, S; Seidl, M; Müller, FU; Schmitz, W; Schlenke, P; McClelland, M; Berdel, WE; Dugas, M; Serve, H; Study Alliance Leukemia
Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia.
Blood. 2010; 116(18): 3564-3571.
Doi: 10.1182/blood-2009-09-240978
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2009
Eisenberg, T; Knauer, H; Schauer, A; Büttner, S; Ruckenstuhl, C; Carmona-Gutierrez, D; Ring, J; Schroeder, S; Magnes, C; Antonacci, L; Fussi, H; Deszcz, L; Hartl, R; Schraml, E; Criollo, A; Megalou, E; Weiskopf, D; Laun, P; Heeren, G; Breitenbach, M; Grubeck-Loebenstein, B; Herker, E; Fahrenkrog, B; Fröhlich, KU; Sinner, F; Tavernarakis, N; Minois, N; Kroemer, G; Madeo, F
Induction of autophagy by spermidine promotes longevity.
Nat Cell Biol. 2009; 11(11):1305-1314
Doi: 10.1038/ncb1975
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Racedo, SE; Wrenzycki, C; Lepikhov, K; Salamone, D; Walter, J; Niemann, H
Epigenetic modifications and related mRNA expression during bovine oocyte in vitro maturation.
Reprod Fertil Dev. 2009; 21(6):738-748
Doi: 10.1071/RD09039
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2008
Akimzhanov, A; Krenacs, L; Schlegel, T; Klein-Hessling, S; Bagdi, E; Stelkovics, E; Kondo, E; Chuvpilo, S; Wilke, P; Avots, A; Gattenlohner, S; Muller-Hermelink, HK; Palmetshofer, A; Serfling, E
Epigenetic changes and suppression of the nuclear factor of activated T cell 1 (NFATC1) promoter in human lymphomas with defects in immunoreceptor signaling.
Am J Pathol. 2008; 172(1):215-224
Doi: 10.2353/ajpath.2008.070294
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2007
Büttner, S; Eisenberg, T; Carmona-Gutierrez, D; Ruli, D; Knauer, H; Ruckenstuhl, C; Sigrist, C; Wissing, S; Kollroser, M; Fröhlich, KU; Sigrist, S; Madeo, F
Endonuclease G regulates budding yeast life and death.
Mol Cell. 2007; 25(2):233-246
Doi: 10.1016/j.molcel.2006.12.021
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2002
Neumeister, P; Albanese, C; Balent, B; Greally, J; Pestell, RG
Senescence and epigenetic dysregulation in cancer.
Int J Biochem Cell Biol. 2002; 34(11):1475-1490
Doi: 10.1016%2FS1357-2725%2802%2900079-1
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