Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Suchbegriffe: CELLS, CULTURED - METABOLISM , . Treffer: 78

2007

Jörgl, A; Platzer, B; Taschner, S; Heinz, LX; Höcher, B; Reisner, PM; Göbel, F; Strobl, H Human Langerhans-cell activation triggered in vitro by conditionally expressed MKK6 is counterregulated by the downstream effector RelB.
Blood. 2007; 109(1):185-193 Doi: 10.1182/blood-2006-05-022954 [OPEN ACCESS]
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Marsche, G; Frank, S; Raynes, JG; Kozarsky, KF; Sattler, W; Malle, E The lipidation status of acute-phase protein serum amyloid A determines cholesterol mobilization via scavenger receptor class B, type I.
Biochem J. 2007; 402(1): 117-124. Doi: 10.1042/BJ20061406 [OPEN ACCESS]
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Nitsche, H; Ramamoorthy, S; Sareban, M; Pausawasdi, N; Todisco, A Functional role of bone morphogenetic protein-4 in isolated canine parietal cells.
Am J Physiol Gastrointest Liver Physiol. 2007; 293(3): G607-G614. Doi: 10.1152/ajpgi.00194.2006 [OPEN ACCESS]
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Panzenboeck, U; Andersson, U; Hansson, M; Sattler, W; Meaney, S; Björkhem, I On the mechanism of cerebral accumulation of cholestanol in patients with cerebrotendinous xanthomatosis.
J Lipid Res. 2007; 48(5): 1167-1174. Doi: 10.1194/jlr.M700027-JLR200 [OPEN ACCESS]
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Ugurel, S; Thirumaran, RK; Bloethner, S; Gast, A; Sucker, A; Mueller-Berghaus, J; Rittgen, W; Hemminki, K; Becker, JC; Kumar, R; Schadendorf, D B-RAF and N-RAS Mutations Are Preserved during Short Time In Vitro Propagation and Differentially Impact Prognosis
PLOS ONE. 2007; 2(2): Doi: 10.1371/journal.pone.0000236 [OPEN ACCESS]
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2005

Malli, R; Frieden, M; Trenker, M; Graier, WF The role of mitochondria for Ca2+ refilling of the endoplasmic reticulum.
J BIOL CHEM. 2005; 280(13): 12114-12122. Doi: 10.1074/jbc.M409353200 [OPEN ACCESS]
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Sedej, S; Rupnik, M; Zorec, R Endocytosis-dominated membrane area decrease requires Rab5 protein in rat melanotrophs.
Ann N Y Acad Sci. 2005; 1048(41):272-280 Doi: 10.1196/annals.1342.024
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2004

Louch, WE; Bito, V; Heinzel, FR; Macianskiene, R; Vanhaecke, J; Flameng, W; Mubagwa, K; Sipido, KR Reduced synchrony of Ca2+ release with loss of T-tubules-a comparison to Ca2+ release in human failing cardiomyocytes.
Cardiovasc Res. 2004; 62(1):63-73 Doi: 10.1016/j.cardiores.2003.12.031 [OPEN ACCESS]
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Shie, FS; Neely, MD; Maezawa, I; Wu, H; Olson, SJ; Jürgens, G; Montine, KS; Montine, TJ Oxidized low-density lipoprotein is present in astrocytes surrounding cerebral infarcts and stimulates astrocyte interleukin-6 secretion.
Am J Pathol. 2004; 164(4):1173-1181 Doi: 10.1016/S0002-9440(10)63205-1 [OPEN ACCESS]
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2003

Ardjomand, N; Ardjomand, N; Schaffler, G; Radner, H; El-Shabrawi, Y Expression of somatostatin receptors in uveal melanomas.
INVEST OPHTHALMOL VISUAL SCI. 2003; 44(3): 980-987. Doi: 10.1167/iovs.02-0481 [OPEN ACCESS]
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Fröhlich, E; Klessen, C Regional differences and post-mortem stability of enzymatic activities in the retinal pigment epithelium.
Graefes Arch Clin Exp Ophthalmol. 2003; 241(5):385-393 Doi: 10.1007/s00417-003-0640-x
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Malli, R; Frieden, M; Osibow, K; Graier, WF Mitochondria efficiently buffer subplasmalemmal Ca2+ elevation during agonist stimulation.
J Biol Chem. 2003; 278(12):10807-10815 Doi: 10.1074/jbc.M212971200 [OPEN ACCESS]
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Petroff, MG; Chen, L; Phillips, TA; Azzola, D; Sedlmayr, P; Hunt, JS B7 family molecules are favorably positioned at the human maternal-fetal interface.
Biol Reprod. 2003; 68(5):1496-1504 Doi: 10.1095/biolreprod.102.010058 [OPEN ACCESS]
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Pineda Torra, I; Claudel, T; Duval, C; Kosykh, V; Fruchart, JC; Staels, B Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor.
Mol Endocrinol. 2003; 17(2):259-272 Doi: 10.1210/me.2002-0120 [OPEN ACCESS]
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Schaider, H; Oka, M; Bogenrieder, T; Nesbit, M; Satyamoorthy, K; Berking, C; Matsushima, K; Herlyn, M Differential response of primary and metastatic melanomas to neutrophils attracted by IL-8.
Int J Cancer. 2003; 103(3):335-343 Doi: 10.1002/ijc.10775
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Wagner, S; Seidler, T; Picht, E; Maier, LS; Kazanski, V; Teucher, N; Schillinger, W; Pieske, B; Isenberg, G; Hasenfuss, G; Kögler, H Na(+)-Ca(2+) exchanger overexpression predisposes to reactive oxygen species-induced injury.
Cardiovasc Res. 2003; 60(2):404-412 Doi: 10.1016/j.cardiores.2003.08.006 [OPEN ACCESS]
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2002

Bochkov, VN; Mechtcheriakova, D; Lucerna, M; Huber, J; Malli, R; Graier, WF; Hofer, E; Binder, BR; Leitinger, N Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca(++)/NFAT.
Blood. 2002; 99(1):199-206 Doi: 10.1182/blood.V99.1.199 [OPEN ACCESS]
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Claudel, T; Sturm, E; Duez, H; Torra, IP; Sirvent, A; Kosykh, V; Fruchart, JC; Dallongeville, J; Hum, DW; Kuipers, F; Staels, B Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element.
J Clin Invest. 2002; 109(7):961-971 Doi: 10.1172/JCI14505 [OPEN ACCESS]
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Holnthoner, W; Pillinger, M; Groger, M; Wolff, K; Ashton, AW; Albanese, C; Neumeister, P; Pestell, RG; Petzelbauer, P Fibroblast growth factor-2 induces Lef/Tcf-dependent transcription in human endothelial cells.
J Biol Chem. 2002; 277(48):45847-45853 Doi: 10.1074/jbc.M209354200 [OPEN ACCESS]
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Leithner, A; Weinhaeusel, A; Windhager, R; Schlegl, R; Waldner, P; Lang, S; Dominkus, M; Zoubek, A; Popper, HH; Haas, OA Absence of SV40 in Austrian tumors correlates with low incidence of mesotheliomas.
Cancer Biol Ther. 2002; 1(4):375-379 Doi: 10.4161/cbt.1.4.10 [OPEN ACCESS]
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Marsche, G; Hammer, A; Oskolkova, O; Kozarsky, KF; Sattler, W; Malle, E Hypochlorite-modified high density lipoprotein, a high affinity ligand to scavenger receptor class B, type I, impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport.
J Biol Chem. 2002; 277(35):32172-32179 Doi: 10.1074/jbc.M200503200 [OPEN ACCESS]
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Pieske, B; Maier, LS; Piacentino, V; Weisser, J; Hasenfuss, G; Houser, S Rate dependence of Na+i and contractility in nonfailing and failing human myocardium.
Circulation. 2002; 106(4):447-453 Doi: 10.1161/01.CIR.0000023042.50192.F4 [OPEN ACCESS]
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Solakoglu, O; Maierhofer, C; Lahr, G; Breit, E; Scheunemann, P; Heumos, I; Pichlmeier, U; Schlimok, G; Oberneder, R; Kollermann, MW; Kollermann, J; Speicher, MR; Pantel, K Heterogeneous proliferative potential of occult metastatic cells in bone marrow of patients with solid epithelial tumors.
Proc Natl Acad Sci U S A. 2002; 99(4):2246-2251 Doi: 10.1073/pnas.042372199 [OPEN ACCESS]
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Vécsey-Semjén, B; Becker, KF; Sinski, A; Blennow, E; Vietor, I; Zatloukal, K; Beug, H; Wagner, E; Huber, LA Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers.
Oncogene. 2002; 21(30):4646-4662 Doi: 10.1038/sj.onc.1205577 [OPEN ACCESS]
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2001

Caplice, NM; Panetta, C; Peterson, TE; Kleppe, LS; Mueske, CS; Kostner, GM; Broze, GJ; Simari, RD Lipoprotein (a) binds and inactivates tissue factor pathway inhibitor: a novel link between lipoproteins and thrombosis.
Blood. 2001; 98(10):2980-2987 Doi: 10.1182/blood.V98.10.2980 [OPEN ACCESS]
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Dandachi, N; Hauser-Kronberger, C; Moré, E; Wiesener, B; Hacker, GW; Dietze, O; Wirl, G Co-expression of tenascin-C and vimentin in human breast cancer cells indicates phenotypic transdifferentiation during tumour progression: correlation with histopathological parameters, hormone receptors, and oncoproteins.
J Pathol. 2001; 193(2):181-189 Doi: 10.1002/1096-9896(2000)9999:9999<::AID-PATH752>3.0.CO;2-V
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Fröhlich, E; Klessen, C Enzymatic heterogeneity of bovine retinal pigment epithelial cells in vivo and in vitro.
Graefes Arch Clin Exp Ophthalmol. 2001; 239(1):25-34 Doi: 10.1007/s004170000218
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Most, P; Bernotat, J; Ehlermann, P; Pleger, ST; Reppel, M; Börries, M; Niroomand, F; Pieske, B; Janssen, PM; Eschenhagen, T; Karczewski, P; Smith, GL; Koch, WJ; Katus, HA; Remppis, A S100A1: a regulator of myocardial contractility.
Proc Natl Acad Sci U S A. 2001; 98(24):13889-13894 Doi: 10.1073/pnas.241393598 [OPEN ACCESS]
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Nuszkowski, A; Gräbner, R; Marsche, G; Unbehaun, A; Malle, E; Heller, R Hypochlorite-modified low density lipoprotein inhibits nitric oxide synthesis in endothelial cells via an intracellular dislocalization of endothelial nitric-oxide synthase.
J Biol Chem. 2001; 276(17):14212-14221 Doi: 10.1074/jbc.M007659200 [OPEN ACCESS]
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Reister, F; Frank, HG; Kingdom, JC; Heyl, W; Kaufmann, P; Rath, W; Huppertz, B Macrophage-induced apoptosis limits endovascular trophoblast invasion in the uterine wall of preeclamptic women.
LAB INVEST 2001 81: 1143-1152. Doi: 10.1038/labinvest.3780326 [OPEN ACCESS]
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Spruck, C; Strohmaier, H; Watson, M; Smith, AP; Ryan, A; Krek, TW; Reed, SI A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.
Mol Cell. 2001; 7(3):639-650 Doi: 10.1016/S1097-2765(01)00210-6 [OPEN ACCESS]
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Strohmaier, H; Spruck, CH; Kaiser, P; Won, KA; Sangfelt, O; Reed, SI Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line.
Nature. 2001; 413(6853):316-322 Doi: 10.1038/35095076
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2000

Bilban, M; Barth, S; Cervar, M; Mauschitz, R; Schaur, RJ; Zivkovic, F; Desoye, G Differential regulation of endothelin secretion and endothelin receptor mRNA levels in JAR, JEG-3, and BeWo choriocarcinoma cell lines and in human trophoblasts, their nonmalignant counterpart.
Arch Biochem Biophys. 2000; 382(2):245-252 Doi: 10.1006/abbi.2000.2016
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Fleischhacker, E; Esenabhalu, VE; Holzmann, S; Skrabal, F; Koidl, B; Kostner, GM; Graier, WF In human hypercholesterolemia increased reactivity of vascular smooth muscle cells is due to altered subcellular Ca(2+) distribution.
Atherosclerosis. 2000; 149(1):33-42 Doi: 10.1016%2FS0021-9150%2899%2900290-7
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Paltauf-Doburzynska, J; Frieden, M; Spitaler, M; Graier, WF Histamine-induced Ca2+ oscillations in a human endothelial cell line depend on transmembrane ion flux, ryanodine receptors and endoplasmic reticulum Ca2+-ATPase.
J PHYSIOL-LONDON. 2000; 524 Pt 3(6): 701-713. Doi: 10.1111%2Fj.1469-7793.2000.00701.x [OPEN ACCESS]
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Pussinen, PJ; Lindner, H; Glatter, O; Reicher, H; Kostner, GM; Wintersperger, A; Malle, E; Sattler, W Lipoprotein-associated alpha-tocopheryl-succinate inhibits cell growth and induces apoptosis in human MCF-7 and HBL-100 breast cancer cells.
BBA-MOL CELL BIOL LIPIDS 2000 1485: 129-144. Doi: 10.1016/S1388-1981(00)00035-4
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1999

Fleischhacker, E; Esenabhalu, VE; Spitaler, M; Holzmann, S; Skrabal, F; Koidl, B; Kostner, GM; Graier, WF Human diabetes is associated with hyperreactivity of vascular smooth muscle cells due to altered subcellular Ca2+ distribution.
Diabetes. 1999; 48(6):1323-1330 Doi: 10.2337/diabetes.48.6.1323 [OPEN ACCESS]
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Graier, WF; Posch, K; Fleischhacker, E; Wascher, TC; Kostner, GM Increased superoxide anion formation in endothelial cells during hyperglycemia: an adaptive response or initial step of vascular dysfunction?
Diabetes Res Clin Pract. 1999; 45(2-3):153-160 Doi: 10.1016%2FS0168-8227%2899%2900045-5
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Hüser, J; Holda, JR; Kockskamper, J; Blatter, LA Focal agonist stimulation results in spatially restricted Ca2+ release and capacitative Ca2+ entry in bovine vascular endothelial cells.
J Physiol. 1999; 514 ( Pt 1)(5): 101-109. Doi: 10.1111/j.1469-7793.1999.101af.x [OPEN ACCESS]
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Karten, B; Boechzelt, H; Abuja, PM; Mittelbach, M; Sattler, W Macrophage-enhanced formation of cholesteryl ester-core aldehydes during oxidation of low density lipoprotein.
J LIPID RES 1999 40: 1240-1253. Doi: 10.1016/S0022-2275(20)33486-6 [OPEN ACCESS]
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Posch, K; Simecek, S; Wascher, TC; Jürgens, G; Baumgartner-Parzer, S; Kostner, GM; Graier, WF Glycated low-density lipoprotein attenuates shear stress-induced nitric oxide synthesis by inhibition of shear stress-activated L-arginine uptake in endothelial cells.
Diabetes. 1999; 48(6):1331-1337 Doi: 10.2337/diabetes.48.6.1331 [OPEN ACCESS]
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Schlenke, P; Kisro, J; Deeken, M; Zajac, S; Klich, S; Wagner, T The cytotoxicity of mafosfamide on G-CSF mobilized hematopoietic progenitors is reduced by SH groups of albumin--implications for further purging strategies.
Bone Marrow Transplant. 1999; 23(2):157-161 Doi: 10.1038/sj.bmt.1701541 [OPEN ACCESS]
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1998

Hahn, T; Barth, S; Weiss, U; Mosgoeller, W; Desoye, G Sustained hyperglycemia in vitro down-regulates the GLUT1 glucose transport system of cultured human term placental trophoblast: a mechanism to protect fetal development?
FASEB J 1998 12: 1221-1231. Doi: 10.1096/fasebj.12.12.1221 [OPEN ACCESS]
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Hoebel, BG; Graier, WF 11,12-Epoxyeicosatrienoic acid stimulates tyrosine kinase activity in porcine aortic endothelial cells.
Eur J Pharmacol. 1998; 346(1):115-117 Doi: 10.1016%2FS0014-2999%2898%2900118-6
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Paltauf-Doburzynska, J; Posch, K; Paltauf, G; Graier, WF Stealth ryanodine-sensitive Ca2+ release contributes to activity of capacitative Ca2+ entry and nitric oxide synthase in bovine endothelial cells.
J Physiol. 1998; 513 ( Pt 2)(2):369-379 Doi: 10.1111%2Fj.1469-7793.1998.369bb.x [OPEN ACCESS]
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1997

Egle, A; Villunger, A; Marschitz, I; Kos, M; Hittmair, A; Lukas, P; Grünewald, K; Greil, R Expression of Apo-1/Fas (CD95), Bcl-2, Bax and Bcl-x in myeloma cell lines: relationship between responsiveness to anti-Fas mab and p53 functional status.
Br J Haematol. 1997; 97(2): 418-428. Doi: 10.1046/j.1365-2141.1997.382680.x
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Graier, WF; Posch, K; Wascher, TC; Kostner, GM Role of superoxide anions in changes of endothelial vasoactive response during acute hyperglycemia.
Horm Metab Res. 1997; 29(12):622-626 Doi: 10.1055/s-2007-979113
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Graier, WF; Simecek, S; Hoebel, BG; Wascher, TC; Dittrich, P; Kostner, GM Antioxidants prevent high-D-glucose-enhanced endothelial Ca2+/cGMP response by scavenging superoxide anions.
Eur J Pharmacol. 1997; 322(1):113-122 Doi: 10.1016%2FS0014-2999%2896%2900989-2
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Oemar, BS; Werner, A; Garnier, JM; Do, DD; Godoy, N; Nauck, M; März, W; Rupp, J; Pech, M; Lüscher, TF Human connective tissue growth factor is expressed in advanced atherosclerotic lesions.
Circulation. 1997; 95(4):831-839 Doi: 10.1161/01.CIR.95.4.831 [OPEN ACCESS]
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Panzenboeck, U; Raitmayer, S; Reicher, H; Lindner, H; Glatter, O; Malle, E; Sattler, W Effects of reagent and enzymatically generated hypochlorite on physicochemical and metabolic properties of high density lipoproteins.
J Biol Chem. 1997; 272(47):29711-29720 Doi: 10.1074%2Fjbc.272.47.29711 [OPEN ACCESS]
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