Suchbegriffe: CARCINOMA, HEPATOCELLULAR - GENETICS , . Treffer: 32
Sladky, VC; Knapp, K; Szabo, TG; Braun, VZ; Bongiovanni, L; van den Bos, H; Spierings, DC; Westendorp, B; Curinha, A; Stojakovic, T; Scharnagl, H; Timelthaler, G; Tsuchia, K; Pinter, M; Semmler, G; Foijer, F; de Bruin, A; Reiberger, T; Rohr-Udilova, N; Villunger, A
PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis.
EMBO Rep. 2020; 21(12):e50893-e50893
Doi: 10.15252/embr.202050893
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Stickel, F; Lutz, P; Buch, S; Nischalke, HD; Silva, I; Rausch, V; Fischer, J; Weiss, KH; Gotthardt, D; Rosendahl, J; Marot, A; Elamly, M; Krawczyk, M; Casper, M; Lammert, F; Buckley, TWM; McQuillin, A; Spengler, U; Eyer, F; Vogel, A; Marhenke, S; von Felden, J; Wege, H; Sharma, R; Atkinson, S; Franke, A; Nehring, S; Moser, V; Schafmayer, C; Spahr, L; Lackner, C; Stauber, RE; Canbay, A; Link, A; Valenti, L; Grove, JI; Aithal, GP; Marquardt, JU; Fateen, W; Zopf, S; Dufour, JF; Trebicka, J; Datz, C; Deltenre, P; Mueller, S; Berg, T; Hampe, J; Morgan, MY
Genetic Variation in HSD17B13 Reduces the Risk of Developing Cirrhosis and Hepatocellular Carcinoma in Alcohol Misusers.
Hepatology. 2020; 72(1):88-102
Doi: 10.1002/hep.30996
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Li, M; Su, Y; Zhang, F; Chen, K; Xu, X; Xu, L; Zhou, J; Wang, W
A dual-targeting reconstituted high density lipoprotein leveraging the synergy of sorafenib and antimiRNA21 for enhanced hepatocellular carcinoma therapy.
Acta Biomater. 2018; 75(10):413-426
Doi: 10.1016/j.actbio.2018.05.049
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Cătană, CS; Pichler, M; Giannelli, G; Mader, RM; Berindan-Neagoe, I
Non-coding RNAs, the Trojan horse in two-way communication between tumor and stroma in colorectal and hepatocellular carcinoma.
Oncotarget. 2017; 8(17):29519-29534
Doi: 10.18632/oncotarget.15706
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Nelson, ME; Lahiri, S; Chow, JD; Byrne, FL; Hargett, SR; Breen, DS; Olzomer, EM; Wu, LE; Cooney, GJ; Turner, N; James, DE; Slack-Davis, JK; Lackner, C; Caldwell, SH; Hoehn, KL
Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival.
Nat Commun. 2017; 8(6):14689-14689
Doi: 10.1038/ncomms14689
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Richtig, G; Aigelsreiter, A; Schwarzenbacher, D; Ress, AL; Adiprasito, JB; Stiegelbauer, V; Hoefler, G; Schauer, S; Kiesslich, T; Kornprat, P; Winder, T; Eisner, F; Gerger, A; Stoeger, H; Stauber, R; Lackner, C; Pichler, M
SOX9 is a proliferation and stem cell factor in hepatocellular carcinoma and possess widespread prognostic significance in different cancer types.
PLoS One. 2017; 12(11):e0187814-e0187814
Doi: 10.1371/journal.pone.0187814
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Jeric, I; Maurer, G; Cavallo, AL; Raguz, J; Desideri, E; Tarkowski, B; Parrini, M; Fischer, I; Zatloukal, K; Baccarini, M
A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nat Commun. 2016; 7(12):13781-13781
Doi: 10.1038/ncomms13781
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Trierweiler, C; Hockenjos, B; Zatloukal, K; Thimme, R; Blum, HE; Wagner, EF; Hasselblatt, P
The transcription factor c-JUN/AP-1 promotes HBV-related liver tumorigenesis in mice.
Cell Death Differ. 2016; 23(4):576-582
Doi: 10.1038/cdd.2015.121
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Elgohary, N; Pellegrino, R; Neumann, O; Elzawahry, HM; Saber, MM; Zeeneldin, AA; Geffers, R; Ehemann, V; Schemmer, P; Schirmacher, P; Longerich, T
Protumorigenic role of Timeless in hepatocellular carcinoma.
Int J Oncol. 2015; 46(2):597-606
Doi: 10.3892/ijo.2014.2751
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Kessler, SM; Laggai, S; Barghash, A; Schultheiss, CS; Lederer, E; Artl, M; Helms, V; Haybaeck, J; Kiemer, AK
IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype.
Cell Death Dis. 2015; 6(1):e1894-e1894
Doi: 10.1038/cddis.2015.241
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Bruns, H; Petrulionis, M; Schultze, D; Al Saeedi, M; Lin, S; Yamanaka, K; Ambrazevičius, M; Strupas, K; Schemmer, P
Glycine inhibits angiogenic signaling in human hepatocellular carcinoma cells.
Amino Acids. 2014; 46(4):969-976
Doi: 10.1007/s00726-013-1662-2
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Friedrich, K; Wannhoff, A; Kattner, S; Brune, M; Hov, JR; Weiss, KH; Antoni, C; Dollinger, M; Neumann-Haefelin, C; Seufferlein, T; Schemmer, P; Schirmacher, P; Stremmel, W; Gotthardt, DN
PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival.
J Gastroenterol Hepatol. 2014; 29(7):1477-1484
Doi: 10.1111/jgh.12540
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Herz, C; Hertrampf, A; Zimmermann, S; Stetter, N; Wagner, M; Kleinhans, C; Erlacher, M; Schüler, J; Platz, S; Rohn, S; Mersch-Sundermann, V; Lamy, E
The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.
J Cell Mol Med. 2014; 18(12): 2393-2403.
Doi: 10.1111/jcmm.12412
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Lanaya, H; Natarajan, A; Komposch, K; Li, L; Amberg, N; Chen, L; Wculek, SK; Hammer, M; Zenz, R; Peck-Radosavljevic, M; Sieghart, W; Trauner, M; Wang, H; Sibilia, M
EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation.
Nat Cell Biol. 2014; 16(10): 1- 7.
Doi: 10.1038/ncb3031
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Welte, S; Urbanik, T; Elßner, C; Kautz, N; Koehler, BC; Waldburger, N; Bermejo, JL; Pinna, F; Weiss, KH; Schemmer, P; Jaeger, D; Longerich, T; Breuhahn, K; Schulze-Bergkamen, H
Nuclear expression of the deubiquitinase CYLD is associated with improved survival in human hepatocellular carcinoma.
PLoS One. 2014; 9(10):e110591-e110591
Doi: 10.1371/journal.pone.0110591
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Aigelsreiter, A; Haybaeck, J; Schauer, S; Kiesslich, T; Bettermann, K; Griessbacher, A; Stojakovic, T; Bauernhofer, T; Samonigg, H; Kornprat, P; Lackner, C; Pichler, M
NEMO expression in human hepatocellular carcinoma and its association with clinical outcome.
Hum Pathol. 2012; 43(7):1012-1019
Doi: 10.1016/j.humpath.2011.08.009
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Neumann, O; Kesselmeier, M; Geffers, R; Pellegrino, R; Radlwimmer, B; Hoffmann, K; Ehemann, V; Schemmer, P; Schirmacher, P; Lorenzo Bermejo, J; Longerich, T
Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors.
Hepatology. 2012; 56(5):1817-1827
Doi: 10.1002/hep.25870
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Radnai, B; Antus, C; Racz, B; Engelmann, P; Priber, JK; Tucsek, Z; Veres, B; Turi, Z; Lorand, T; Sumegi, B; Gallyas, F
Protective effect of the poly(ADP-ribose) polymerase inhibitor PJ34 on mitochondrial depolarization-mediated cell death in hepatocellular carcinoma cells involves attenuation of c-Jun N-terminal kinase-2 and protein kinase B/Akt activation.
Mol Cancer. 2012; 11(5): 34-34.
Doi: 10.1186/1476-4598-11-34
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Haybaeck, J; Zeller, N; Heikenwalder, M
The parallel universe: microRNAs and their role in chronic hepatitis, liver tissue damage and hepatocarcinogenesis.
SWISS MED WKLY. 2011; 141(4): w13287-w13287.
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Hoffmann, K; Shibo, L; Xiao, Z; Longerich, T; Büchler, MW; Schemmer, P
Correlation of gene expression of ATP-binding cassette protein and tyrosine kinase signaling pathway in patients with hepatocellular carcinoma.
Anticancer Res. 2011; 31(11):3883-3890
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Hoffmann, K; Franz, C; Xiao, Z; Mohr, E; Serba, S; Büchler, MW; Schemmer, P
Sorafenib modulates the gene expression of multi-drug resistance mediating ATP-binding cassette proteins in experimental hepatocellular carcinoma.
Anticancer Res. 2010; 30(11):4503-4508
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Tomuleasa, C; Soritau, O; Rus-Ciuca, D; Pop, T; Todea, D; Mosteanu, O; Pintea, B; Foris, V; Susman, S; Kacsó, G; Irimie, A
Isolation and characterization of hepatic cancer cells with stem-like properties from hepatocellular carcinoma.
J Gastrointestin Liver Dis. 2010; 19(1):61-67
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Vernadakis, S; Poetsch, M; Weber, F; Treckmann, J; Mathe, Z; Baba, HA; Paul, A; Kaiser, GM
Donor origin de novo HCC in a noncirrhotic liver allograft 3 years after liver transplantation.
Transpl Int. 2010; 23(3):341-343
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Aigelsreiter, A; Janig, E; Sostaric, J; Pichler, M; Unterthor, D; Halasz, J; Lackner, C; Zatloukal, K; Denk, H
Clusterin expression in cholestasis, hepatocellular carcinoma and liver fibrosis.
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A lymphotoxin-driven pathway to hepatocellular carcinoma.
CANCER CELL. 2009; 16(4): 295-308.
Doi: 10.1016/j.ccr.2009.08.021
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Kashofer, K; Tschernatsch, MM; Mischinger, HJ; Iberer, F; Zatloukal, K
The disease relevance of human hepatocellular xenograft models: molecular characterization and review of the literature.
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Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA.
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Schachtrup, C; Emmler, T; Bleck, B; Sandqvist, A; Spener, F
Functional analysis of peroxisome-proliferator-responsive element motifs in genes of fatty acid-binding proteins.
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