Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: CARCINOMA, HEPATOCELLULAR - GENETICS , . Treffer: 32

2020

Sladky, VC; Knapp, K; Szabo, TG; Braun, VZ; Bongiovanni, L; van den Bos, H; Spierings, DC; Westendorp, B; Curinha, A; Stojakovic, T; Scharnagl, H; Timelthaler, G; Tsuchia, K; Pinter, M; Semmler, G; Foijer, F; de Bruin, A; Reiberger, T; Rohr-Udilova, N; Villunger, A PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis.
EMBO Rep. 2020; 21(12):e50893-e50893 Doi: 10.15252/embr.202050893 [OPEN ACCESS]
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Stickel, F; Lutz, P; Buch, S; Nischalke, HD; Silva, I; Rausch, V; Fischer, J; Weiss, KH; Gotthardt, D; Rosendahl, J; Marot, A; Elamly, M; Krawczyk, M; Casper, M; Lammert, F; Buckley, TWM; McQuillin, A; Spengler, U; Eyer, F; Vogel, A; Marhenke, S; von Felden, J; Wege, H; Sharma, R; Atkinson, S; Franke, A; Nehring, S; Moser, V; Schafmayer, C; Spahr, L; Lackner, C; Stauber, RE; Canbay, A; Link, A; Valenti, L; Grove, JI; Aithal, GP; Marquardt, JU; Fateen, W; Zopf, S; Dufour, JF; Trebicka, J; Datz, C; Deltenre, P; Mueller, S; Berg, T; Hampe, J; Morgan, MY Genetic Variation in HSD17B13 Reduces the Risk of Developing Cirrhosis and Hepatocellular Carcinoma in Alcohol Misusers.
Hepatology. 2020; 72(1):88-102 Doi: 10.1002/hep.30996 [OPEN ACCESS]
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2018

Li, M; Su, Y; Zhang, F; Chen, K; Xu, X; Xu, L; Zhou, J; Wang, W A dual-targeting reconstituted high density lipoprotein leveraging the synergy of sorafenib and antimiRNA21 for enhanced hepatocellular carcinoma therapy.
Acta Biomater. 2018; 75(10):413-426 Doi: 10.1016/j.actbio.2018.05.049
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2017

Cătană, CS; Pichler, M; Giannelli, G; Mader, RM; Berindan-Neagoe, I Non-coding RNAs, the Trojan horse in two-way communication between tumor and stroma in colorectal and hepatocellular carcinoma.
Oncotarget. 2017; 8(17):29519-29534 Doi: 10.18632/oncotarget.15706 [OPEN ACCESS]
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Nelson, ME; Lahiri, S; Chow, JD; Byrne, FL; Hargett, SR; Breen, DS; Olzomer, EM; Wu, LE; Cooney, GJ; Turner, N; James, DE; Slack-Davis, JK; Lackner, C; Caldwell, SH; Hoehn, KL Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival.
Nat Commun. 2017; 8(6):14689-14689 Doi: 10.1038/ncomms14689 [OPEN ACCESS]
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Richtig, G; Aigelsreiter, A; Schwarzenbacher, D; Ress, AL; Adiprasito, JB; Stiegelbauer, V; Hoefler, G; Schauer, S; Kiesslich, T; Kornprat, P; Winder, T; Eisner, F; Gerger, A; Stoeger, H; Stauber, R; Lackner, C; Pichler, M SOX9 is a proliferation and stem cell factor in hepatocellular carcinoma and possess widespread prognostic significance in different cancer types.
PLoS One. 2017; 12(11):e0187814-e0187814 Doi: 10.1371/journal.pone.0187814 [OPEN ACCESS]
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2016

Jeric, I; Maurer, G; Cavallo, AL; Raguz, J; Desideri, E; Tarkowski, B; Parrini, M; Fischer, I; Zatloukal, K; Baccarini, M A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nat Commun. 2016; 7(12):13781-13781 Doi: 10.1038/ncomms13781 [OPEN ACCESS]
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Trierweiler, C; Hockenjos, B; Zatloukal, K; Thimme, R; Blum, HE; Wagner, EF; Hasselblatt, P The transcription factor c-JUN/AP-1 promotes HBV-related liver tumorigenesis in mice.
Cell Death Differ. 2016; 23(4):576-582 Doi: 10.1038/cdd.2015.121 [OPEN ACCESS]
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2015

Elgohary, N; Pellegrino, R; Neumann, O; Elzawahry, HM; Saber, MM; Zeeneldin, AA; Geffers, R; Ehemann, V; Schemmer, P; Schirmacher, P; Longerich, T Protumorigenic role of Timeless in hepatocellular carcinoma.
Int J Oncol. 2015; 46(2):597-606 Doi: 10.3892/ijo.2014.2751 [OPEN ACCESS]
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Kessler, SM; Laggai, S; Barghash, A; Schultheiss, CS; Lederer, E; Artl, M; Helms, V; Haybaeck, J; Kiemer, AK IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype.
Cell Death Dis. 2015; 6(1):e1894-e1894 Doi: 10.1038/cddis.2015.241 [OPEN ACCESS]
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2014

Bruns, H; Petrulionis, M; Schultze, D; Al Saeedi, M; Lin, S; Yamanaka, K; Ambrazevičius, M; Strupas, K; Schemmer, P Glycine inhibits angiogenic signaling in human hepatocellular carcinoma cells.
Amino Acids. 2014; 46(4):969-976 Doi: 10.1007/s00726-013-1662-2
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Friedrich, K; Wannhoff, A; Kattner, S; Brune, M; Hov, JR; Weiss, KH; Antoni, C; Dollinger, M; Neumann-Haefelin, C; Seufferlein, T; Schemmer, P; Schirmacher, P; Stremmel, W; Gotthardt, DN PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival.
J Gastroenterol Hepatol. 2014; 29(7):1477-1484 Doi: 10.1111/jgh.12540
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Herz, C; Hertrampf, A; Zimmermann, S; Stetter, N; Wagner, M; Kleinhans, C; Erlacher, M; Schüler, J; Platz, S; Rohn, S; Mersch-Sundermann, V; Lamy, E The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC.
J Cell Mol Med. 2014; 18(12): 2393-2403. Doi: 10.1111/jcmm.12412 [OPEN ACCESS]
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Lanaya, H; Natarajan, A; Komposch, K; Li, L; Amberg, N; Chen, L; Wculek, SK; Hammer, M; Zenz, R; Peck-Radosavljevic, M; Sieghart, W; Trauner, M; Wang, H; Sibilia, M EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation.
Nat Cell Biol. 2014; 16(10): 1- 7. Doi: 10.1038/ncb3031 [OPEN ACCESS]
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Welte, S; Urbanik, T; Elßner, C; Kautz, N; Koehler, BC; Waldburger, N; Bermejo, JL; Pinna, F; Weiss, KH; Schemmer, P; Jaeger, D; Longerich, T; Breuhahn, K; Schulze-Bergkamen, H Nuclear expression of the deubiquitinase CYLD is associated with improved survival in human hepatocellular carcinoma.
PLoS One. 2014; 9(10):e110591-e110591 Doi: 10.1371/journal.pone.0110591 [OPEN ACCESS]
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2012

Aigelsreiter, A; Haybaeck, J; Schauer, S; Kiesslich, T; Bettermann, K; Griessbacher, A; Stojakovic, T; Bauernhofer, T; Samonigg, H; Kornprat, P; Lackner, C; Pichler, M NEMO expression in human hepatocellular carcinoma and its association with clinical outcome.
Hum Pathol. 2012; 43(7):1012-1019 Doi: 10.1016/j.humpath.2011.08.009
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Neumann, O; Kesselmeier, M; Geffers, R; Pellegrino, R; Radlwimmer, B; Hoffmann, K; Ehemann, V; Schemmer, P; Schirmacher, P; Lorenzo Bermejo, J; Longerich, T Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors.
Hepatology. 2012; 56(5):1817-1827 Doi: 10.1002/hep.25870 [OPEN ACCESS]
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Radnai, B; Antus, C; Racz, B; Engelmann, P; Priber, JK; Tucsek, Z; Veres, B; Turi, Z; Lorand, T; Sumegi, B; Gallyas, F Protective effect of the poly(ADP-ribose) polymerase inhibitor PJ34 on mitochondrial depolarization-mediated cell death in hepatocellular carcinoma cells involves attenuation of c-Jun N-terminal kinase-2 and protein kinase B/Akt activation.
Mol Cancer. 2012; 11(5): 34-34. Doi: 10.1186/1476-4598-11-34 [OPEN ACCESS]
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2011

Haybaeck, J; Zeller, N; Heikenwalder, M The parallel universe: microRNAs and their role in chronic hepatitis, liver tissue damage and hepatocarcinogenesis.
SWISS MED WKLY. 2011; 141(4): w13287-w13287. Doi: 10.4414/smw.2011.13287 [OPEN ACCESS]
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Hoffmann, K; Shibo, L; Xiao, Z; Longerich, T; Büchler, MW; Schemmer, P Correlation of gene expression of ATP-binding cassette protein and tyrosine kinase signaling pathway in patients with hepatocellular carcinoma.
Anticancer Res. 2011; 31(11):3883-3890
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2010

Hoffmann, K; Franz, C; Xiao, Z; Mohr, E; Serba, S; Büchler, MW; Schemmer, P Sorafenib modulates the gene expression of multi-drug resistance mediating ATP-binding cassette proteins in experimental hepatocellular carcinoma.
Anticancer Res. 2010; 30(11):4503-4508
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Tomuleasa, C; Soritau, O; Rus-Ciuca, D; Pop, T; Todea, D; Mosteanu, O; Pintea, B; Foris, V; Susman, S; Kacsó, G; Irimie, A Isolation and characterization of hepatic cancer cells with stem-like properties from hepatocellular carcinoma.
J Gastrointestin Liver Dis. 2010; 19(1):61-67 [OPEN ACCESS]
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Vernadakis, S; Poetsch, M; Weber, F; Treckmann, J; Mathe, Z; Baba, HA; Paul, A; Kaiser, GM Donor origin de novo HCC in a noncirrhotic liver allograft 3 years after liver transplantation.
Transpl Int. 2010; 23(3):341-343 Doi: 10.1111/j.1432-2277.2009.00942.x (- Case Report)
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2009

Aigelsreiter, A; Janig, E; Sostaric, J; Pichler, M; Unterthor, D; Halasz, J; Lackner, C; Zatloukal, K; Denk, H Clusterin expression in cholestasis, hepatocellular carcinoma and liver fibrosis.
Histopathology. 2009; 54(5): 561-570. Doi: 10.1111/j.1365-2559.2009.03258.x
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Haybaeck, J; Zeller, N; Wolf, MJ; Weber, A; Wagner, U; Kurrer, MO; Bremer, J; Iezzi, G; Graf, R; Clavien, PA; Thimme, R; Blum, H; Nedospasov, SA; Zatloukal, K; Ramzan, M; Ciesek, S; Pietschmann, T; Marche, PN; Karin, M; Kopf, M; Browning, JL; Aguzzi, A; Heikenwalder, M A lymphotoxin-driven pathway to hepatocellular carcinoma.
CANCER CELL. 2009; 16(4): 295-308. Doi: 10.1016/j.ccr.2009.08.021 [OPEN ACCESS]
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Kashofer, K; Tschernatsch, MM; Mischinger, HJ; Iberer, F; Zatloukal, K The disease relevance of human hepatocellular xenograft models: molecular characterization and review of the literature.
Cancer Lett. 2009; 286(1):121-128 Doi: 10.1016/j.canlet.2008.11.011
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2008

Trauner, M; Fickert, P; Halilbasic, E; Moustafa, T Lessons from the toxic bile concept for the pathogenesis and treatment of cholestatic liver diseases.
Wien Med Wochenschr. 2008; 158(19-20):542-548 Doi: 10.1007/s10354-008-0592-1
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2007

Panzitt, K; Tschernatsch, MM; Guelly, C; Moustafa, T; Stradner, M; Strohmaier, HM; Buck, CR; Denk, H; Schroeder, R; Trauner, M; Zatloukal, K Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA.
Gastroenterology. 2007; 132(1):330-342 Doi: 10.1053/j.gastro.2006.08.026
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2004

Oberkofler, H; Schraml, E; Krempler, F; Patsch, W Restoration of sterol-regulatory-element-binding protein-1c gene expression in HepG2 cells by peroxisome-proliferator-activated receptor-gamma co-activator-1alpha.
Biochem J. 2004; 381(Pt 2): 357-363. Doi: 10.1042/BJ20040173 [OPEN ACCESS]
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Schachtrup, C; Emmler, T; Bleck, B; Sandqvist, A; Spener, F Functional analysis of peroxisome-proliferator-responsive element motifs in genes of fatty acid-binding proteins.
Biochem J. 2004; 382(Pt 1):239-245 Doi: 10.1042/BJ20031340 [OPEN ACCESS]
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1995

Kubicka, S; Trautwein, C; Schrem, H; Tillmann, H; Manns, M Low incidence of p53 mutations in European hepatocellular carcinomas with heterogeneous mutation as a rare event.
J Hepatol. 1995; 23(4):412-419 Doi: 10.1016/0168-8278(95)80199-5
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1991

Chen, GL; Balfe, A; Erwa, W; Hoefler, G; Gaertner, J; Aikawa, J; Chen, WW Import of human bifunctional enzyme into peroxisomes of human hepatoma cells in vitro.
Biochem Biophys Res Commun. 1991; 178(3):1084-1091 Doi: 10.1016/0006-291X(91)91003-U
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