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Publikationen

Suchbegriffe: CARCINOMA - GENETICS , . Treffer: 55

2023

Baněčková, M; Thompson, LDR; Hyrcza, MD; Vaněček, T; Agaimy, A; Laco, J; Simpson, RHW; Di, Palma, S; Stevens, TM; Brcic, L; Etebarian, A; Dimnik, K; Majewska, H; Stárek, I; O'Regan, E; Salviato, T; Helliwell, T; Horáková, M; Biernat, W; Onyuma, T; Michal, M; Leivo, I; Skalova, A Salivary Gland Secretory Carcinoma: Clinicopathologic and Genetic Characteristics of 215 Cases and Proposal for a Grading System.
AM J SURG PATHOL. 2023; 47(6): 661-677. Doi: 10.1097/PAS.0000000000002043
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Enko, D; Schaflinger, E; Müller, DJ [Clinical Application Examples of a Next-Generation Sequencing based Multi-Genepanel Analysis].
Dtsch Med Wochenschr. 2023; 148(11): 695-702. Doi: 10.1055/a-2033-5329
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2022

Cyrta, J; Rosiene, J; Bareja, R; Kudman, S; Al, Zoughbi, W; Motanagh, S; Wilkes, DC; Eng, K; Zhang, T; Sticca, E; Mathew, S; Rubin, MA; Sboner, A; Elemento, O; Rubin, BP; Imielinski, M; Mosquera, JM Whole-genome characterization of myoepithelial carcinomas of the soft tissue.
Cold Spring Harb Mol Case Stud. 2022; 8(7): Doi: 10.1101/mcs.a006227 [OPEN ACCESS]
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Penkert, J; Strüwe, FJ; Dutzmann, CM; Doergeloh, BB; Montellier, E; Freycon, C; Keymling, M; Schlemmer, HP; Sänger, B; Hoffmann, B; Gerasimov, T; Blattmann, C; Fetscher, S; Frühwald, M; Hettmer, S; Kordes, U; Ridola, V; Kroiss, Benninger, S; Mastronuzzi, A; Schott, S; Nees, J; Prokop, A; Redlich, A; Seidel, MG; Zimmermann, S; Pajtler, KW; Pfister, SM; Hainaut, P; Kratz, CP Genotype-phenotype associations within the Li-Fraumeni spectrum: a report from the German Registry.
J Hematol Oncol. 2022; 15(1): 107 Doi: 10.1186/s13045-022-01332-1 [OPEN ACCESS]
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2018

Deshwar, A; Margonis, GA; Andreatos, N; Barbon, C; Wang, J; Buettner, S; Wagner, D; Sasaki, K; Beer, A; Løes, IM; Pikoulis, E; Damaskos, C; Garmpis, N; Kamphues, K; He, J; Kaczirek, K; Poultsides, G; Lønning, PE; Mischinger, HJ; Aucejo, FN; Kreis, ME; Wolfgang, CL; Weiss, MJ Double KRAS and BRAF Mutations in Surgically Treated Colorectal Cancer Liver Metastases: An International, Multi-institutional Case Series.
Anticancer Res. 2018; 38(5):2891-2895 Doi: 10.21873/anticanres.12535 (- Case Report) [OPEN ACCESS]
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Gantenbein, N; Bernhart, E; Anders, I; Golob-Schwarzl, N; Krassnig, S; Wodlej, C; Brcic, L; Lindenmann, J; Fink-Neuboeck, N; Gollowitsch, F; Stacher-Priehse, E; Asslaber, M; Gogg-Kamerer, M; Rolff, J; Hoffmann, J; Silvestri, A; Regenbrecht, C; Reinhard, C; Pehserl, AM; Pichler, M; Sokolova, O; Naumann, M; Mitterer, V; Pertschy, B; Bergler, H; Popper, H; Sattler, W; Haybaeck, J Influence of eukaryotic translation initiation factor 6 on non-small cell lung cancer development and progression.
Eur J Cancer. 2018; 101(4):165-180 Doi: 10.1016/j.ejca.2018.07.001 [OPEN ACCESS]
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2017

Dandachi, N; Tiran, V; Lindenmann, J; Brcic, L; Fink-Neuboeck, N; Kashofer, K; Absenger, G; Bezan, A; Cote, RJ; Datar, R; Balic, M Frequency and clinical impact of preoperative circulating tumor cells in resectable non-metastatic lung adenocarcinomas.
Lung Cancer. 2017; 113(46):152-157 Doi: 10.1016/j.lungcan.2017.10.003
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Račkauskas, R; Zhou, D; Ūselis, S; Strupas, K; Herr, I; Schemmer, P Sulforaphane sensitizes human cholangiocarcinoma to cisplatin via the downregulation of anti-apoptotic proteins.
Oncol Rep. 2017; 37(6):3660-3666 Doi: 10.3892/or.2017.5622 [OPEN ACCESS]
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Woischke, C; Schaaf, CW; Yang, HM; Vieth, M; Veits, L; Geddert, H; Märkl, B; Stömmer, P; Schaeffer, DF; Frölich, M; Blum, H; Vosberg, S; Greif, PA; Jung, A; Kirchner, T; Horst, D In-depth mutational analyses of colorectal neuroendocrine carcinomas with adenoma or adenocarcinoma components.
Mod Pathol. 2017; 30(1): 95-103. Doi: 10.1038/modpathol.2016.150
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2016

Al-Zoughbi, W; Pichler, M; Gorkiewicz, G; Guertl-Lackner, B; Haybaeck, J; Jahn, SW; Lackner, C; Liegl-Atzwanger, B; Popper, H; Schauer, S; Nusshold, E; Kindt, AS; Trajanoski, Z; Speicher, MR; Haemmerle, G; Zimmermann, R; Zechner, R; Vesely, PW; Hoefler, G Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.
Oncotarget. 2016; 7(23):33832-33840 Doi: 10.18632/oncotarget.9418 [OPEN ACCESS]
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Bonin, S; Donada, M; Bussolati, G; Nardon, E; Annaratone, L; Pichler, M; Chiaravalli, AM; Capella, C; Hoefler, G; Stanta, G A synonymous EGFR polymorphism predicting responsiveness to anti-EGFR therapy in metastatic colorectal cancer patients.
Tumour Biol. 2016; 37(6):7295-7303 Doi: 10.1007/s13277-015-4543-3
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Busch, SE; Hanke, ML; Kargl, J; Metz, HE; MacPherson, D; Houghton, AM Lung Cancer Subtypes Generate Unique Immune Responses.
J Immunol. 2016; 197(11):4493-4503 Doi: 10.4049/jimmunol.1600576 [OPEN ACCESS]
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Cerk, S; Schwarzenbacher, D; Adiprasito, JB; Stotz, M; Hutterer, GC; Gerger, A; Ling, H; Calin, GA; Pichler, M Current Status of Long Non-Coding RNAs in Human Breast Cancer.
Int J Mol Sci. 2016; 17(9): Doi: 10.3390/ijms17091485 [OPEN ACCESS]
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He, JC; Yao, W; Wang, JM; Schemmer, P; Yang, Y; Liu, Y; Qian, YW; Qi, WP; Zhang, J; Shen, Q; Yang, T TACC3 overexpression in cholangiocarcinoma correlates with poor prognosis and is a potential anti-cancer molecular drug target for HDAC inhibitors.
Oncotarget. 2016; 7(46):75441-75456 Doi: 10.18632/oncotarget.12254 [OPEN ACCESS]
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Jagadeeshan, S; Subramanian, A; Tentu, S; Beesetti, S; Singhal, M; Raghavan, S; Surabhi, RP; Mavuluri, J; Bhoopalan, H; Biswal, J; Pitani, RS; Chidambaram, S; Sundaram, S; Malathi, R; Jeyaraman, J; Nair, AS; Venkatraman, G; Rayala, SK P21-activated kinase 1 (Pak1) signaling influences therapeutic outcome in pancreatic cancer.
Ann Oncol. 2016; 27(8): 1546-1556. Doi: 10.1093/annonc/mdw184 [OPEN ACCESS]
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Kammerer, S; Jahn, SW; Winter, E; Eidenhammer, S; Rezania, S; Regitnig, P; Pichler, M; Schreibmayer, W; Bauernhofer, T Critical evaluation of KCNJ3 gene product detection in human breast cancer: mRNA in situ hybridisation is superior to immunohistochemistry.
J Clin Pathol. 2016; 69(12):1116-1121 Doi: 10.1136/jclinpath-2016-203798 [OPEN ACCESS]
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Ling, H; Pickard, K; Ivan, C; Isella, C; Ikuo, M; Mitter, R; Spizzo, R; Bullock, M; Braicu, C; Pileczki, V; Vincent, K; Pichler, M; Stiegelbauer, V; Hoefler, G; Almeida, MI; Hsiao, A; Zhang, X; Primrose, J; Packham, G; Liu, K; Bojja, K; Gafà, R; Xiao, L; Rossi, S; Song, JH; Vannini, I; Fanini, F; Kopetz, S; Zweidler-McKay, P; Wang, X; Ionescu, C; Irimie, A; Fabbri, M; Lanza, G; Hamilton, SR; Berindan-Neagoe, I; Medico, E; Mirnezami, A; Calin, GA; Nicoloso, MS The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis.
Gut. 2016; 65(6):977-989 Doi: 10.1136/gutjnl-2015-309372 [OPEN ACCESS]
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Metz, HE; Kargl, J; Busch, SE; Kim, KH; Kurland, BF; Abberbock, SR; Randolph-Habecker, J; Knoblaugh, SE; Kolls, JK; White, MF; Houghton, AM Insulin receptor substrate-1 deficiency drives a proinflammatory phenotype in KRAS mutant lung adenocarcinoma.
Proc Natl Acad Sci U S A. 2016; 113(31):8795-8800 Doi: 10.1073/pnas.1601989113 [OPEN ACCESS]
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Perakis, SO; Thomas, JE; Pichler, M Non-coding RNAs Enabling Prognostic Stratification and Prediction of Therapeutic Response in Colorectal Cancer Patients.
Adv Exp Med Biol. 2016; 937(4):183-204 Doi: 10.1007/978-3-319-42059-2_10
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Weber, ML; Schneider, DT; Offenmüller, S; Kaatsch, P; Einsiedel, HG; Benesch, M; Claviez, A; Ebinger, M; Kramm, C; Kratz, C; Lawlor, J; Leuschner, I; Merkel, S; Metzler, M; Nustede, R; Petsch, S; Seeger, KH; Schlegel, PG; Suttorp, M; Zolk, O; Brecht, IB Pediatric Colorectal Carcinoma is Associated With Excellent Outcome in the Context of Cancer Predisposition Syndromes.
Pediatr Blood Cancer. 2016; 63(4):611-617 Doi: 10.1002/pbc.25839
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2015

Popper, HH Lung adenocarcinomas: comparison between mice and men.
Methods Mol Biol. 2015; 1267(2):19-43 Doi: 10.1007/978-1-4939-2297-0_2
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2014

Fröhlich, E; Wahl, R The current role of targeted therapies to induce radioiodine uptake in thyroid cancer.
CANCER TREAT REV. 2014; 40(5): 665-674. Doi: 10.1016/j.ctrv.2014.01.002
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Ress, AL; Stiegelbauer, V; Schwarzenbacher, D; Deutsch, A; Perakis, S; Ling, H; Ivan, C; Calin, GA; Rinner, B; Gerger, A; Pichler, M Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer.
Oncotarget. 2014; 5(18):8492-8502 Doi: 10.18632/oncotarget.2329 [OPEN ACCESS]
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Szkandera, J; Pichler, M; Absenger, G; Stotz, M; Weissmueller, M; Samonigg, H; Asslaber, M; Lax, S; Leitner, G; Winder, T; Renner, W; Gerger, A A functional germline variant in GLI1 implicates hedgehog signaling in clinical outcome of stage II and III colon carcinoma patients.
Clin Cancer Res. 2014; 20(6):1687-1697 Doi: 10.1158/1078-0432.CCR-13-1517 [OPEN ACCESS]
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2013

Bindea, G; Mlecnik, B; Tosolini, M; Kirilovsky, A; Waldner, M; Obenauf, AC; Angell, H; Fredriksen, T; Lafontaine, L; Berger, A; Bruneval, P; Fridman, WH; Becker, C; Pagès, F; Speicher, MR; Trajanoski, Z; Galon, J Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.
Immunity. 2013; 39(4):782-795 Doi: 10.1016/j.immuni.2013.10.003 [OPEN ACCESS]
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Dijkstra, JR; Heideman, DA; Meijer, GA; Boers, JE; 't Hart, NA; Diebold, J; Hirschmann, A; Hoefler, G; Winter, G; Miltenberger-Miltenyi, G; Pereira, SV; Richman, SD; Quirke, P; Rouleau, EL; Guinebretiere, JM; Tejpar, S; Biesmans, B; van Krieken, JH KRAS mutation analysis on low percentage of colon cancer cells: the importance of quality assurance.
Virchows Arch. 2013; 462(1):39-46 Doi: 10.1007/s00428-012-1356-2
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Heitzer, E; Lax, S; Lafer, I; Müller, SM; Pristauz, G; Ulz, P; Jahn, S; Högenauer, C; Petru, E; Speicher, MR; Geigl, JB Multiplex genetic cancer testing identifies pathogenic mutations in TP53 and CDH1 in a patient with bilateral breast and endometrial adenocarcinoma.
BMC Med Genet. 2013; 14(1):129-129 Doi: 10.1186/1471-2350-14-129 (- Case Report) [OPEN ACCESS]
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Murali, R; Wiesner, T; Scolyer, RA Tumours associated with BAP1 mutations.
Pathology. 2013; 45(2):116-126 Doi: 10.1097/PAT.0b013e32835d0efb
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2012

van Krieken, JH; Hoefler, G The times have changed: molecular pathology is here to stay. A commentary on: analytical performance of a PCR assay for the detection of KRAS mutations (codons 12/13 and 61) in formalin-fixed paraffin-embedded tissue samples of colorectal carcinoma, by Lee et al. In this issue.
VIRCHOWS ARCH. 2012; 460(2): 129-130. Doi: 10.1007/s00428-012-1197-z [OPEN ACCESS]
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2011

Bauernhofer, T; Pichler, M; Wieckowski, E; Stanson, J; Aigelsreiter, A; Griesbacher, A; Groselj-Strele, A; Linecker, A; Samonigg, H; Langner, C; Whiteside, TL Prolactin receptor is a negative prognostic factor in patients with squamous cell carcinoma of the head and neck.
Br J Cancer. 2011; 104(10):1641-1648 Doi: 10.1038/bjc.2011.131 [OPEN ACCESS]
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Betge, J; Pollheimer, MJ; Schlemmer, A; Hoefler, G; Langner, C Gastric cancer and concomitant renal cancer: a systematic immunohistochemical and molecular analysis.
Oncol Rep. 2011; 26(3):567-575 Doi: 10.3892/or.2011.1346 [OPEN ACCESS]
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Jahn, SW; Winter, G; Stacher, E; Halbwedl, I; Gattenlöhner, S; Stockinger, R; Spreitzer, S; Waldispuehl-Geigl, J; Geigl, JB; Offner, F; Hoefler, G Multiple intratumoral KRAS mutations can clonally segregate to different lymph node metastases in colon cancer.
Histopathology. 2011; 59(2): 342-345. Doi: 10.1111/j.1365-2559.2011.03902.x (- Case Report)
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Winder, T; Ning, Y; Yang, D; Zhang, W; Power, DG; Bohanes, P; Gerger, A; Wilson, PM; Lurje, G; Tang, LH; Shah, M; Lenz, HJ Germline polymorphisms in genes involved in the CD44 signaling pathway are associated with clinical outcome in localized gastric adenocarcinoma.
Int J Cancer. 2011; 129(5):1096-1104 Doi: 10.1002/ijc.25787 [OPEN ACCESS]
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2010

Pristauz, G; Petru, E; Stacher, E; Geigl, JB; Schwarzbraun, T; Tsybrovskyy, O; Winter, R; Moinfar, F Androgen receptor expression in breast cancer patients tested for BRCA1 and BRCA2 mutations.
Histopathology. 2010; 57(6):877-884 Doi: 10.1111/j.1365-2559.2010.03724.x
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Timmermann, B; Kerick, M; Roehr, C; Fischer, A; Isau, M; Boerno, ST; Wunderlich, A; Barmeyer, C; Seemann, P; Koenig, J; Lappe, M; Kuss, AW; Garshasbi, M; Bertram, L; Trappe, K; Werber, M; Herrmann, BG; Zatloukal, K; Lehrach, H; Schweiger, MR Somatic Mutation Profiles of MSI and MSS Colorectal Cancer Identified by Whole Exome Next Generation Sequencing and Bioinformatics Analysis
PLOS ONE. 2010; 5(12): e15661-e15661. Doi: 10.1371/journal.pone.0015661 [OPEN ACCESS]
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2009

Mischek, D; Steinborn, R; Petznek, H; Bichler, C; Zatloukal, K; Stürzl, M; Günzburg, WH; Hohenadl, C Molecularly characterised xenograft tumour mouse models: valuable tools for evaluation of new therapeutic strategies for secondary liver cancers.
J Biomed Biotechnol. 2009; 2009(5): 437284-437284. Doi: 10.1155/2009/437284 [OPEN ACCESS]
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2008

Rauh, A; Windischhofer, W; Kovacevic, A; DeVaney, T; Huber, E; Semlitsch, M; Leis, HJ; Sattler, W; Malle, E Endothelin (ET)-1 and ET-3 promote expression of c-fos and c-jun in human choriocarcinoma via ET(B) receptor-mediated G(i)- and G(q)-pathways and MAP kinase activation.
Br J Pharmacol. 2008; 154(1):13-24 Doi: 10.1038/bjp.2008.92 [OPEN ACCESS]
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Trauner, M; Fickert, P; Halilbasic, E; Moustafa, T Lessons from the toxic bile concept for the pathogenesis and treatment of cholestatic liver diseases.
Wien Med Wochenschr. 2008; 158(19-20):542-548 Doi: 10.1007/s10354-008-0592-1
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2007

Kidd, M; Nadler, B; Mane, S; Eick, G; Malfertheiner, M; Champaneria, M; Pfragner, R; Modlin, I GeneChip, geNorm, and gastrointestinal tumors: novel reference genes for real-time PCR.
PHYSIOL GENOMICS. 2007; 30(3): 363-370. Doi: 10.1152/physiolgenomics.00251.2006 [OPEN ACCESS]
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2006

Brücher, BL; Geddert, H; Langner, C; Höfler, H; Fink, U; Siewert, JR; Sarbia, M Hypermethylation of hMLH1, HPP1, p14(ARF), p16(INK4A) and APC in primary adenocarcinomas of the small bowel.
Int J Cancer. 2006; 119(6): 1298-1302. Doi: 10.1002/ijc.21990 [OPEN ACCESS]
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Warnatz, K; Bossaller, L; Salzer, U; Skrabl-Baumgartner, A; Schwinger, W; van der Burg, M; van Dongen, JJ; Orlowska-Volk, M; Knoth, R; Durandy, A; Draeger, R; Schlesier, M; Peter, HH; Grimbacher, B Human ICOS deficiency abrogates the germinal center reaction and provides a monogenic model for common variable immunodeficiency.
BLOOD. 2006; 107(8): 3045-3052. Doi: 10.1182/blood-2005-07-2955 [OPEN ACCESS]
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2004

Bucher, P; Mathe, Z; Bosco, D; Oberholzer, J; Toso, C; Andres, A; Buhler, L; Morel, P; Berney, T Microbial surveillance during human pancreatic islet isolation.
Transplant Proc. 2004; 36(4):1147-1148 Doi: 10.1016/j.transproceed.2004.04.025
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Stacher, E; Ullmann, R; Halbwedl, I; Gogg-Kammerer, M; Boccon-Gibod, L; Nicholson, AG; Sheppard, MN; Carvalho, L; Franca, MT; Macsweeney, F; Morresi-Hauf, A; Popper, HH Atypical goblet cell hyperplasia in congenital cystic adenomatoid malformation as a possible preneoplasia for pulmonary adenocarcinoma in childhood: A genetic analysis.
HUM PATHOL. 2004; 35(5): 565-570. Doi: 10.1016%2Fj.humpath.2004.01.008 [OPEN ACCESS]
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2003

Haedicke, W; Popper, HH; Buck, CR; Zatloukal, K Automated evaluation and normalization of immunohistochemistry on tissue microarrays with a DNA microarray scanner.
Biotechniques. 2003; 35(1):164-168 Doi: 10.2144/03351md04 [OPEN ACCESS]
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Mannweiler, S; Dinges, HP; Beham-Schmid, C; Hauser, H; Starlinger, M; Regauer, S Colliding / concomitant tumors of the intestine: report of 3 cases.
PATHOL ONCOL RES. 2003; 9(3): 188-192. Doi: PAOR.2003.9.3.0188 (- Case Report) [OPEN ACCESS]
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Tsybrovskyy, O; Berghold, A Application of multilevel models to morphometric data. Part 1. Linear models and hypothesis testing.
Anal Cell Pathol. 2003; 25(4):173-185 Doi: 10.1155/2003/506712 [OPEN ACCESS]
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Ullmann, R; Bongiovanni, M; Halbwedl, I; Petzmann, S; Gogg-Kammerer, M; Sapino, A; Papotti, M; Bussolati, G; Popper, HH Bronchiolar columnar cell dysplasia--genetic analysis of a novel preneoplastic lesion of peripheral lung.
Virchows Arch. 2003; 442(5):429-436 Doi: 10.1007/s00428-003-0797-z
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2002

Rudroff, C; Seibold, S; Kaufmann, R; Zetina, CC; Reise, K; Schäfer, U; Schneider, A; Brockmann, M; Scheele, J; Neugebauer, EA Expression of the thrombin receptor PAR-1 correlates with tumour cell differentiation of pancreatic adenocarcinoma in vitro.
Clin Exp Metastasis. 2002; 19(2):181-189 Doi: 10.1023/A:1014598904644
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Spruck, CH; Strohmaier, H; Sangfelt, O; Müller, HM; Hubalek, M; Müller-Holzner, E; Marth, C; Widschwendter, M; Reed, SI hCDC4 gene mutations in endometrial cancer.
Cancer Res. 2002; 62(16):4535-4539 [OPEN ACCESS]
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2001

Grote, HJ; Friedrichs, N; Pomjanski, N; Guhde, HF; Reich, O; Böcking, A Prognostic significance of DNA cytometry in carcinoma of the uterine cervix FIGO stage IB and II.
Anal Cell Pathol. 2001; 23(3-4):97-105 Doi: 10.1155/2001/602976 [OPEN ACCESS]
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