Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: CDK4, . Treffer: 30

2025

DeMichele, A; Dueck, AC; Hlauschek, D; Martin, M; Burstein, H; Pfeiler, G; Zdenkowski, N; Wolff, A; Bellet-Ezquerra, M; Winer, E; Balic, M; Miller, K; Colleoni, M; Lake, D; Rubovsky, G; Cameron, D; Balko, J; Singer, CF; Nowecki, Z; Iwata, H; Wolmark, N; Parraga, KA; Rugo, H; Steger, GG; Traina, T; Werutsky, G; Czajkowska, D; Metzger, O; El-Abed, S; Theall, KP; Lu, RD; O'Brien, P; Fesl, C; Mayer, E; Gnant, M Outcomes in stage IIA versus stage IIB/III in the PALLAS trial [ABCSG-42/AFT-05/PrE0109/BIG-14-13]).
Breast Cancer Res. 2025; 27(1):12 Doi: 10.1186/s13058-024-01941-3 [OPEN ACCESS]
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Klocker, EV; Egle, D; Bartsch, R; Rinnerthaler, G; Gnant, M Efficacy and Safety of CDK4/6 Inhibitors: A Focus on HR+/HER2- Early Breast Cancer.
Drugs. 2025; Doi: 10.1007/s40265-024-02144-y [OPEN ACCESS]
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Schneider, JS; Ben Khaled, N; Ye, LT; Wimmer, R; Hammann, L; Weich, A; Suppan, C; Mahajan, UM; Jung, AD; Kumbrink, J; Denk, G; Rau, M; Kunzmann, V; Kuss, S; Neuman, J; Mayerle, J; Geier, A; Hermanns, HM; De Toni, EN; Reiter, FP Efficacy of CDK4/6 Inhibition in colorectal cancer and the role of p16 expression in predicting drug resistance
CELL ONCOL. 2025; Doi: 10.1007/s13402-025-01080-7
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2024

Gnant, M; Balic, M; Singer, CF; Rinnerthaler, G; Pfeiler, G; Suppan, C; Grünberger, B; Strasser-Weippl, K; Castagnaviz, V; Heibl, S; Bartsch, R Evolving treatment paradigms after CDK4/6 inhibitors in advanced breast cancer
MEMO-MAG EUR MED ONC. 2024; Doi: 10.1007/s12254-024-01012-5
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2023

Borchert, S; Mathilakathu, A; Nath, A; Wessolly, M; Mairinger, E; Kreidt, D; Steinborn, J; Walter, RFH; Christoph, DC; Kollmeier, J; Wohlschlaeger, J; Mairinger, T; Brcic, L; Mairinger, FD Cancer-Associated Fibroblasts Influence Survival in Pleural Mesothelioma: Digital Gene Expression Analysis and Supervised Machine Learning Model.
Int J Mol Sci. 2023; 24(15): Doi: 10.3390/ijms241512426 [OPEN ACCESS]
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Gnant, M; Singer, CF; Rinnerthaler, G; Pfeiler, G; Egle, D; Balic, M; Bartsch, R Position paper on CDK4/6 inhibitors in early breast cancer
MEMO-MAG EUR MED ONC. 2023; Doi: 10.1007/s12254-023-00878-1
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Pfeiler, G; Hlauschek, D; Mayer, EL; Deutschmann, C; Kacerovsky-Strobl, S; Martin, M; Meisel, JL; Zdenkowski, N; Loibl, S; Balic, M; Park, H; Prat, A; Isaacs, C; Bajetta, E; Balko, JM; Bellet-Ezquerra, M; Bliss, J; Burstein, H; Cardoso, F; Fohler, H; Foukakis, T; Gelmon, KA; Goetz, M; Haddad, TC; Iwata, H; Jassem, J; Lee, SC; Linderholm, B; Los, M; Mamounas, EP; Miller, KD; Morris, PG; Munzone, E; Gal-Yam, EN; Ring, A; Shepherd, L; Singer, C; Thomssen, C; Tseng, LM; Valagussa, P; Winer, EP; Wolff, AC; Zoppoli, G; Machacek-Link, J; Schurmans, C; Huang, X; Gauthier, E; Fesl, C; Dueck, AC; DeMichele, A; Gnant, M, , PALLAS, Groups, and, Investigators Impact of BMI in Patients With Early Hormone Receptor-Positive Breast Cancer Receiving Endocrine Therapy With or Without Palbociclib in the PALLAS Trial.
J Clin Oncol. 2023; JCO2300126 Doi: 10.1200/JCO.23.00126
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Turkovic, L; Koraj, N; Mlinaric, Z; Silovski, T; Crnkovic, S; Sertic, M Optimisation of dispersive liquid-liquid microextraction for plasma sample preparation in bioanalysis of CDK4/6 inhibitors in therapeutic combinations for breast cancer treatment
HELIYON. 2023; 9(8): e18880 Doi: 10.1016/j.heliyon.2023.e18880 [OPEN ACCESS]
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2022

Mayer, EL; Fesl, C; Hlauschek, D; Garcia-Estevez, L; Burstein, HJ; Zdenkowski, N; Wette, V; Miller, KD; Balic, M; Mayer, IA; Cameron, D; Winer, EP; Ponce, Lorenzo, JJ; Lake, D; Pristauz-Telsnigg, G; Haddad, TC; Shepherd, L; Iwata, H; Goetz, M; Cardoso, F; Traina, TA; Sabanathan, D; Breitenstein, U; Ackerl, K; Metzger, Filho, O; Zehetner, K; Solomon, K; El-Abed, S; Theall, KP; Lu, DR; Dueck, A; Gnant, M; DeMichele, A Treatment Exposure and Discontinuation in the PALbociclib CoLlaborative Adjuvant Study of Palbociclib With Adjuvant Endocrine Therapy for Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Early Breast Cancer (PALLAS/AFT-05/ABCSG-42/BIG-14-03).
J Clin Oncol. 2022; JCO2101918 Doi: 10.1200/JCO.21.01918 [OPEN ACCESS]
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Moik, F; Ay, C Venous and arterial thromboembolism in patients with cancer treated with targeted anti-cancer therapies
THROMB RES. 2022; 213: S58-S65. Doi: 10.1016/j.thromres.2022.01.004
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Suppan, C ESMO 2021-my top three abstracts in breast cancer
MEMO-MAG EUR MED ONC. 2022; Doi: 10.1007/s12254-022-00810-z [OPEN ACCESS]
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Turkovic, L; Bockor, L; Ekpenyong, O; Silovski, T; Lovric, M; Crnkovic, S; Nigovic, B; Sertic, M Development and Validation of a Novel LC-MS/MS Method for the Simultaneous Determination of Abemaciclib, Palbociclib, Ribociclib, Anastrozole, Letrozole, and Fulvestrant in Plasma Samples: A Prerequisite for Personalized Breast Cancer Treatment
PHARMACEUTICALS-BASE. 2022; 15(5): 614 Doi: 10.3390/ph15050614 [OPEN ACCESS]
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2021

Dandachi, N; Posch, F; Graf, R; Suppan, C; Klocker, EV; Müller, HD; Lindenmann, J; Terbuch, A; Heitzer, E; Balic, M Longitudinal tumor fraction trajectories predict risk of progression in metastatic HR+ breast cancer patients undergoing CDK4/6 treatment.
Mol Oncol. 2021; 15(9):2390-2400 Doi: 10.1002/1878-0261.12870 [OPEN ACCESS]
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2020

Birnhuber, A; Egemnazarov, B; Biasin, V; Bonyadi Rad, E; Wygrecka, M; Olschewski, H; Kwapiszewska, G; Marsh, LM CDK4/6 inhibition enhances pulmonary inflammatory infiltration in bleomycin-induced lung fibrosis.
Respir Res. 2020; 21(1):167-167 Doi: 10.1186/s12931-020-01433-w [OPEN ACCESS]
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Gajzer, DC; Fletcher, CD; Agaimy, A; Brcic, I; Khanlari, M; Rosenberg, AE Primary gastrointestinal liposarcoma-a clinicopathological study of 8 cases of a rare entity.
Hum Pathol. 2019; 97:80-93 Doi: 10.1016/j.humpath.2019.12.004
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Gampenrieder, SP; Castagnaviz, V; Rinnerthaler, G; Greil, R Treatment Landscape for Patients with HER2-Positive Metastatic Breast Cancer: A Review on Emerging Treatment Options.
Cancer Manag Res. 2020; 12:10615-10629 Doi: 10.2147/CMAR.S235121 [OPEN ACCESS]
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Koch, C; Kuske, A; Joosse, SA; Yigit, G; Sflomos, G; Thaler, S; Smit, DJ; Werner, S; Borgmann, K; Gärtner, S; Mossahebi Mohammadi, P; Battista, L; Cayrefourcq, L; Altmüller, J; Salinas-Riester, G; Raithatha, K; Zibat, A; Goy, Y; Ott, L; Bartkowiak, K; Tan, TZ; Zhou, Q; Speicher, MR; Müller, V; Gorges, TM; Jücker, M; Thiery, JP; Brisken, C; Riethdorf, S; Alix-Panabières, C; Pantel, K Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity.
EMBO Mol Med. 2020; 12(9):e11908-e11908 Doi: 10.15252/emmm.201911908 [OPEN ACCESS]
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2018

Rinnerthaler, G; Gampenrieder, SP; Greil, R ASCO 2018 highlights: metastatic breast cancer.
Memo. 2018; 11(4): 276-279. Doi: 10.1007/s12254-018-0450-9 [OPEN ACCESS]
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Rinnerthaler, G; Gampenrieder, SP; Greil, R SABCS 2017: lifestyle factors, hormone receptor-positive advanced disease, liquid biopsies, and prognosis.
Memo. 2018; 11(3): 208-212. Doi: 10.1007/s12254-018-0433-x [OPEN ACCESS]
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2016

Gampenrieder, SP; Rinnerthaler, G; Greil, R CDK4/6 inhibition in luminal breast cancer.
Memo. 2016; 9: 76-81. Doi: 10.1007/s12254-016-0268-2 [OPEN ACCESS]
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Müller, C; Wendt, J; Rauscher, S; Burgstaller-Muehlbacher, S; Sunder-Plassmann, R; Scheurecker, C; Richtig, E; Fae, I; Fischer, G; Pehamberger, H; Okamoto, I Characterization of patients at high risk of melanoma in Austria.
BRIT J DERMATOL. 2016; 174(6): 1308-1317. Doi: 10.1111/bjd.14407
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Ohtsuka, M; Ling, H; Ivan, C; Pichler, M; Matsushita, D; Goblirsch, M; Stiegelbauer, V; Shigeyasu, K; Zhang, X; Chen, M; Vidhu, F; Bartholomeusz, GA; Toiyama, Y; Kusunoki, M; Doki, Y; Mori, M; Song, S; Gunther, JR; Krishnan, S; Slaby, O; Goel, A; Ajani, JA; Radovich, M; Calin, GA H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer.
EBioMedicine. 2016; 13(3):113-124 Doi: 10.1016/j.ebiom.2016.10.026 [OPEN ACCESS]
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2015

Aoude, LG; Heitzer, E; Johansson, P; Gartside, M; Wadt, K; Pritchard, AL; Palmer, JM; Symmons, J; Gerdes, AM; Montgomery, GW; Martin, NG; Tomlinson, I; Kearsey, S; Hayward, NK POLE mutations in families predisposed to cutaneous melanoma.
Fam Cancer. 2015; 14(4):621-628 Doi: 10.1007/s10689-015-9826-8
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2014

Bernhart, E; Damm, S; Heffeter, P; Wintersperger, A; Asslaber, M; Frank, S; Hammer, A; Strohmaier, H; DeVaney, T; Mrfka, M; Eder, H; Windpassinger, C; Ireson, CR; Mischel, PS; Berger, W; Sattler, W Silencing of protein kinase D2 induces glioma cell senescence via p53-dependent and -independent pathways.
Neuro Oncol. 2014; 16(7):933-945 Doi: 10.1093/neuonc/not303 [OPEN ACCESS]
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Fric, J; Lim, CX; Mertes, A; Lee, BT; Viganò, E; Chen, J; Zolezzi, F; Poidinger, M; Larbi, A; Strobl, H; Zelante, T; Ricciardi-Castagnoli, P Calcium and calcineurin-NFAT signaling regulate granulocyte-monocyte progenitor cell cycle via Flt3-L.
Stem Cells. 2014; 32(12):3232-3244 Doi: 10.1002/stem.1813 [OPEN ACCESS]
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2013

Kollmann, K; Heller, G; Schneckenleithner, C; Warsch, W; Scheicher, R; Ott, RG; Schäfer, M; Fajmann, S; Schlederer, M; Schiefer, AI; Reichart, U; Mayerhofer, M; Hoeller, C; Zöchbauer-Müller, S; Kerjaschki, D; Bock, C; Kenner, L; Hoefler, G; Freissmuth, M; Green, AR; Moriggl, R; Busslinger, M; Malumbres, M; Sexl, V A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis.
Cancer Cell. 2013; 24(2):167-181 Doi: 10.1016/j.ccr.2013.07.012 [OPEN ACCESS]
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2012

Shirsath, NP; Manohar, SM; Joshi, KS P276-00, a cyclin-dependent kinase inhibitor, modulates cell cycle and induces apoptosis in vitro and in vivo in mantle cell lymphoma cell lines.
Mol Cancer. 2012; 11:77-77 Doi: 10.1186/1476-4598-11-77 [OPEN ACCESS]
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2006

Fargnoli, MC; Argenziano, G; Zalaudek, I; Peris, K High- and low-penetrance cutaneous melanoma susceptibility genes.
EXPERT REV ANTICANCER THER. 2006; 6: 657-670. Doi: 10.1586/14737140.6.5.657
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1997

Kovar, H; Jug, G; Aryee, DN; Zoubek, A; Ambros, P; Gruber, B; Windhager, R; Gadner, H Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors.
Oncogene. 1997; 15(18):2225-2232 Doi: 10.1038/sj.onc.1201397 [OPEN ACCESS]
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1995

Sill, H; Goldman, JM; Cross, NC Homozygous deletions of the p16 tumor-suppressor gene are associated with lymphoid transformation of chronic myeloid leukemia.
Blood. 1995; 85(8):2013-2016 Doi: 10.1182/blood.V85.8.2013.bloodjournal8582013 [OPEN ACCESS]
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