Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Publikationen

Suchbegriffe: AUTOPHAGY, . Treffer: 119

2023

Montegut, L; Joseph, A; Chen, H; Abdellatif, M; Ruckenstuhl, C; Motino, O; Lambertucci, F; Anagnostopoulos, G; Lachkar, S; Dichtinger, S; Maiuri, MC; Goldwasser, F; Blanchet, B; Fumeron, F; Martins, I; Madeo, F; Kroemer, G High plasma concentrations of acyl-coenzyme A binding protein (ACBP) predispose to cardiovascular disease: Evidence for a phylogenetically conserved proaging function of ACBP
AGING CELL. 2023; 22(1): Doi: 10.1111/acel.13751 [OPEN ACCESS]
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Monteuta, L; Joseph, A; Chena, H; Abdellatif, M; Ruckenstuhlg, C; Martins, I; Madeo, F; Kroemer, G DBI/ACBP is a targetable autophagy checkpoint involved in aging and cardiovascular disease
AUTOPHAGY. 2023; Doi: 10.1080/15548627.2022.2160565
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2022

Abdellatif, M; Bugger, H; Kroemer, G; Sedej, S NAD+ and Vascular Dysfunction: From Mechanisms to Therapeutic Opportunities.
J Lipid Atheroscler. 2022; 11(2): 111-132. Doi: 10.12997/jla.2022.11.2.111 [OPEN ACCESS]
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Abdellatif, M; Eisenberg, T; Heberle, AM; Thedieck, K; Kroemer, G; Sedej, S Cardiac PI3K p110 alpha attenuation delays aging and extends lifespan
CELL STRESS. 2022; 6(8): 72-75. Doi: 10.15698/cst2022.08.270 [OPEN ACCESS]
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Abdellatif, M; Kroemer, G Heart failure with preserved ejection fraction: An age-related condition
J MOL CELL CARDIOL. 2022; 167: 83-84. Doi: 10.1016/j.yjmcc.2022.03.008
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Abdellatif, M; Madeo, F; Kroemer, G; Sedej, S Spermidine overrides INSR (insulin receptor)-IGF1R (insulin-like growth factor 1 receptor)-mediated inhibition of autophagy in the aging heart.
Autophagy. 2022; 18(10):2500-2502 Doi: 10.1080/15548627.2022.2095835 [OPEN ACCESS]
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Abdellatif, M; Trummer-Herbst, V; Heberle, AM; Humnig, A; Pendl, T; Durand, S; Cerrato, G; Hofer, SJ; Islam, M; Voglhuber, J; Ramos, Pittol, JM; Kepp, O; Hoefler, G; Schmidt, A; Rainer, PP; Scherr, D; von, Lewinski, D; Bisping, E; McMullen, JR; Diwan, A; Eisenberg, T; Madeo, F; Thedieck, K; Kroemer, G; Sedej, S Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity.
Circulation. 2022; 145(25):1853-1866 Doi: 10.1161/CIRCULATIONAHA.122.059863 [OPEN ACCESS]
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Anand, U; Shteinfer-Kuzmine, A; Sela, G; Santhanam, M; Gottschalk, B; Boujemaa-Paterski, R; Medalia, O; Graier, WF; Shoshan-Barmatz, V The Multicellular Effects of VDAC1 N-Terminal-Derived Peptide.
Biomolecules. 2022; 12(10): Doi: 10.3390/biom12101387 [OPEN ACCESS]
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Bradić, I; Kuentzel, KB; Honeder, S; Grabner, GF; Vujić, N; Zimmermann, R; Birner-Gruenberger, R; Kratky, D Off-target effects of the lysosomal acid lipase inhibitors Lalistat-1 and Lalistat-2 on neutral lipid hydrolases.
Mol Metab. 2022; 61:101510 Doi: 10.1016/j.molmet.2022.101510 [OPEN ACCESS]
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Chao, X; Wang, S; Fulte, S; Ma, X; Ahamed, F; Cui, W; Liu, Z; Rülicke, T; Zatloukal, K; Zong, WX; Liu, W; Ni, HM; Ding, WX Hepatocytic p62 suppresses ductular reaction and tumorigenesis in mouse livers with mTORC1 activation and defective autophagy.
J Hepatol. 2022; 76(3):639-651 Doi: 10.1016/j.jhep.2021.10.014 [OPEN ACCESS]
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Gross, D; Bischof, H; Maier, S; Sporbeck, K; Birkenfeld, AL; Malli, R; Ruth, P; Proikas-Cezanne, T; Lukowski, R IKCa channels control breast cancer metabolism including AMPK-driven autophagy.
Cell Death Dis. 2022; 13(10): 902 Doi: 10.1038/s41419-022-05329-z [OPEN ACCESS]
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Huang, R; Dai, Q; Yang, R; Duan, Y; Zhao, Q; Haybaeck, J; Yang, Z A Review: PI3K/AKT/mTOR Signaling Pathway and Its Regulated Eukaryotic Translation Initiation Factors May Be a Potential Therapeutic Target in Esophageal Squamous Cell Carcinoma.
Front Oncol. 2022; 12: 817916 Doi: 10.3389/fonc.2022.817916 [OPEN ACCESS]
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Karacay, C; Prietl, B; Harer, C; Ehall, B; Haudum, CW; Bounab, K; Franz, J; Eisenberg, T; Madeo, F; Kolb, D; Hingerl, K; Hausl, M; Magnes, C; Mautner, SI; Kotzbeck, P; Pieber, TR The effect of spermidine on autoimmunity and beta cell function in NOD mice.
Sci Rep. 2022; 12(1):4502 Doi: 10.1038/s41598-022-08168-2 [OPEN ACCESS]
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Klingseisen, V; Slanovc, J; Regouc, M; Hrzenjak, A Bisdemethoxycurcumin sensitizes the response of cisplatin resistant non-small cell lung carcinoma cell lines by activating apoptosis and autophagy
J NUTR BIOCHEM. 2022; 106: 109003 Doi: 10.1016/j.jnutbio.2022.109003
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Ljubojević-Holzer, S; Kraler, S; Djalinac, N; Abdellatif, M; Voglhuber, J; Schipke, J; Schmidt, M; Kling, KM; Franke, GT; Herbst, V; Zirlik, A; von, Lewinski, D; Scherr, D; Rainer, PP; Kohlhaas, M; Nickel, A; Mühlfeld, C; Maack, C; Sedej, S Loss of autophagy protein ATG5 impairs cardiac capacity in mice and humans through diminishing mitochondrial abundance and disrupting Ca2+ cycling.
Cardiovasc Res. 2022; 118(6):1492-1505 Doi: 10.1093/cvr/cvab112 [OPEN ACCESS]
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Palackic, A; Jay, JW; Duggan, RP; Branski, LK; Wolf, SE; Ansari, N; El, Ayadi, A Therapeutic Strategies to Reduce Burn Wound Conversion.
Medicina (Kaunas). 2022; 58(7): Doi: 10.3390/medicina58070922 [OPEN ACCESS]
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Singh, B; Avula, K; Sufi, SA; Parwin, N; Das, S; Alam, MF; Samantaray, S; Bankapalli, L; Rani, A; Poornima, K; Prusty, B; Mallick, TP; Shaw, SK; Dodia, H; Kabi, S; Pagad, TT; Mohanty, S; Syed, GH Defective Mitochondrial Quality Control during Dengue Infection Contributes to Disease Pathogenesis
J VIROL. 2022; Doi: 10.1128/jvi.00828-22 [OPEN ACCESS]
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Taucher, E; Mykoliuk, I; Fediuk, M; Smolle-Juettner, FM Autophagy, Oxidative Stress and Cancer Development.
CANCERS. 2022; 14(7): Doi: 10.3390/cancers14071637 [OPEN ACCESS]
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Wicik, Z; Nowak, A; Jarosz-Popek, J; Wolska, M; Eyileten, C; Siller-Matula, JM; von, Lewinski, D; Sourij, H; Filipiak, KJ; Postuła, M Characterization of the SGLT2 Interaction Network and Its Regulation by SGLT2 Inhibitors: A Bioinformatic Analysis.
Front Pharmacol. 2022; 13: 901340 Doi: 10.3389/fphar.2022.901340 [OPEN ACCESS]
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2021

Abdellatif, M; Kroemer, G Co-ordinated mitochondrial degradation by autophagy and heterophagy in cardiac homeostasis.
Cardiovasc Res. 2021; 117(1):e1-e3-e1-e3 Doi: 10.1093/cvr/cvaa345 [OPEN ACCESS]
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Babalola, JA; Lang, M; George, M; Stracke, A; Tadic, J; Madeo, F; Lass, A; Leitinger, G; Hutter-Paier, B; Hoefler, G; Panzenboeck, U Astaxanthin enhances LRP1-modulated insulin sensitivity and amyloid beta clearance in an in vitro blood-brain barrier model.
Alzheimers Dement. AAIC 2021 Abstracts. 2021; 17 Suppl 3: e053736--Alzheimer’s Association International Conference, AAIC 2021; JULY 26-30, 2021; Denver, USA. Doi: 10.1002/alz.053736 [Poster]
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Fellner, L; Gabassi, E; Haybaeck, J; Edenhofer, F Autophagy in α-Synucleinopathies-An Overstrained System.
Cells. 2021; 10(11): Doi: 10.3390/cells10113143 [OPEN ACCESS]
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Gallob, F; Brcic, L; Eidenhammer, S; Rumpp, F; Nerlich, A; Popper, H Senescence and autophagy in usual interstitial pneumonia of different etiology.
Virchows Arch. 2021; 478(3):497-506 Doi: 10.1007/s00428-020-02917-2 [OPEN ACCESS]
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Klionsky, DJ; Abdel-Aziz, AK; Abdelfatah, S; Abdellatif, M; Abdoli, A; Abel, S; Abeliovich, H; Abildgaard, MH; Abudu, YP; Acevedo-Arozena, A; Adamopoulos, IE; Adeli, K; Adolph, TE; Adornetto, A; Aflaki, E; Agam, G; Agarwal, A; Aggarwal, BB; Agnello, M; Agostinis, P; Agrewala, JN; Agrotis, A; Aguilar, PV; Ahmad, ST; Ahmed, ZM; Ahumada-Castro, U; Aits, S; Aizawa, S; Akkoc, Y; Akoumianaki, T; Akpinar, HA; Al-Abd, AM; Al-Akra, L; Al-Gharaibeh, A; Alaoui-Jamali, MA; Alberti, S; Alcocer-Gómez, E; Alessandri, C; Ali, M; Alim, Al-Bari, MA; Aliwaini, S; Alizadeh, J; Almacellas, E; Almasan, A; Alonso, A; Alonso, GD; Altan-Bonnet, N; Altieri, DC; Álvarez, ÉMC; Alves, S; Alves, da, Costa, C; Alzaharna, MM; Amadio, M; Amantini, C; Amaral, C; Ambrosio, S; Amer, AO; Ammanathan, V; An, Z; Andersen, SU; Andrabi, SA; Andrade-Silva, M; Andres, AM; Angelini, S; et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
AUTOPHAGY. 2021; 17(1): 1-382. Doi: 10.1080/15548627.2020.1797280 [OPEN ACCESS]
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Kuscuoglu, D; Bewersdorf, L; Wenzel, K; Gross, A; Kobazi Ensari, G; Luo, Y; Kilic, K; Hittatiya, K; Golob-Schwarzl, N; Leube, RE; Preisinger, C; George, J; Metwally, M; Eslam, M; Lampertico, P; Petta, S; Mangia, A; Berg, T; Boonstra, A; Brouwer, WP; Abate, ML; Loglio, A; Sutton, A; Nahon, P; Schaefer, B; Zoller, H; Aigner, E; Trautwein, C; Haybaeck, J; Strnad, P Dual proteotoxic stress accelerates liver injury via activation of p62-Nrf2.
J Pathol. 2021; 254(1):80-91 Doi: 10.1002/path.5643
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Lindenmann, J; Smolle, C; Kamolz, LP; Smolle-Juettner, FM; Graier, WF Survey of Molecular Mechanisms of Hyperbaric Oxygen in Tissue Repair.
Int J Mol Sci. 2021; 22(21): Doi: 10.3390/ijms222111754 [OPEN ACCESS]
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Lohberger, B; Glaenzer, D; Eck, N; Steinecker-Frohnwieser, B; Leithner, A; Rinner, B; Kerschbaum-Gruber, S; Georg, D Effects of a combined therapy of bortezomib and ionizing radiation on chondrosarcoma three-dimensional spheroid cultures.
Oncol Lett. 2021; 21(6): 428-428. Doi: 10.3892/ol.2021.12689 [OPEN ACCESS]
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Panzitt, K; Fickert, P; Wagner, M Regulation of autophagy by bile acids and in cholestasis - CholestoPHAGY or CholeSTOPagy.
Biochim Biophys Acta Mol Basis Dis. 2021; 1867(2):166017-166017 Doi: 10.1016/j.bbadis.2020.166017
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Panzitt, K; Wagner, M FXR in liver physiology: Multiple faces to regulate liver metabolism
BBA-MOL BASIS DIS. 2021; 1867(7): 166133 Doi: 10.1016/j.bbadis.2021.166133 [OPEN ACCESS]
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Pignet, AL; Schellnegger, M; Hecker, A; Kohlhauser, M; Kotzbeck, P; Kamolz, LP Resveratrol-Induced Signal Transduction in Wound Healing.
Int J Mol Sci. 2021; 22(23): Doi: 10.3390/ijms222312614 [OPEN ACCESS]
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Qian, H; Bai, Q; Yang, X; Akakpo, JY; Ji, L; Yang, L; Rülicke, T; Zatloukal, K; Jaeschke, H; Ni, HM; Ding, WX Dual roles of p62/SQSTM1 in the injury and recovery phases of acetaminophen-induced liver injury in mice.
Acta Pharm Sin B. 2021; 11(12):3791-3805 Doi: 10.1016/j.apsb.2021.11.010 [OPEN ACCESS]
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Schroeder, S; Hofer, SJ; Zimmermann, A; Pechlaner, R; Dammbrueck, C; Pendl, T; Marcello, GM; Pogatschnigg, V; Bergmann, M; Müller, M; Gschiel, V; Ristic, S; Tadic, J; Iwata, K; Richter, G; Farzi, A; Üçal, M; Schäfer, U; Poglitsch, M; Royer, P; Mekis, R; Agreiter, M; Tölle, RC; Sótonyi, P; Willeit, J; Mairhofer, B; Niederkofler, H; Pallhuber, I; Rungger, G; Tilg, H; Defrancesco, M; Marksteiner, J; Sinner, F; Magnes, C; Pieber, TR; Holzer, P; Kroemer, G; Carmona-Gutierrez, D; Scorrano, L; Dengjel, J; Madl, T; Sedej, S; Sigrist, SJ; Rácz, B; Kiechl, S; Eisenberg, T; Madeo, F Dietary spermidine improves cognitive function.
Cell Rep. 2021; 35(2):108985-108985 Doi: 10.1016/j.celrep.2021.108985 [OPEN ACCESS]
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Voglhuber, J; Ljubojevic-Holzer, S; Abdellatif, M; Sedej, S Targeting Cardiovascular Risk Factors Through Dietary Adaptations and Caloric Restriction Mimetics.
Front Nutr. 2021; 8: 758058 Doi: 10.3389/fnut.2021.758058 [OPEN ACCESS]
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Vujić, N; Bradić, I; Goeritzer, M; Kuentzel, KB; Rainer, S; Kratky, D; Radović, B ATG7 is dispensable for LC3-PE conjugation in thioglycolate-elicited mouse peritoneal macrophages.
Autophagy. 2021; 17(11):3402-3407 Doi: 10.1080/15548627.2021.1874132 [OPEN ACCESS]
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Zimmermann, A; Madreiter-Sokolowski, C; Stryeck, S; Abdellatif, M Targeting the Mitochondria-Proteostasis Axis to Delay Aging.
FRONT CELL DEV BIOL. 2021; 9(3): 656201-656201. Doi: 10.3389/fcell.2021.656201 [OPEN ACCESS]
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2020

Abdellatif, M; Ljubojevic-Holzer, S; Madeo, F; Sedej, S Autophagy in cardiovascular health and disease.
Prog Mol Biol Transl Sci. 2020; 172:87-106 Doi: 10.1016/bs.pmbts.2020.04.022
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Duan, Y; Haybaeck, J; Yang, Z Therapeutic Potential of PI3K/AKT/mTOR Pathway in Gastrointestinal Stromal Tumors: Rationale and Progress.
Cancers (Basel). 2020; 12(10): Doi: 10.3390/cancers12102972 [OPEN ACCESS]
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Gollmer, J; Zirlik, A; Bugger, H Mitochondrial Mechanisms in Diabetic Cardiomyopathy.
Diabetes Metab J. 2020; 44(1):33-53 Doi: 10.4093/dmj.2019.0185 [OPEN ACCESS]
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Panzitt, K; Jungwirth, E; Krones, E; Lee, JM; Pollheimer, M; Thallinger, GG; Kolb-Lenz, D; Xiao, R; Thorell, A; Trauner, M; Fickert, P; Marschall, HU; Moore, DD; Wagner, M FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis.
J Hepatol. 2020; 72(6):1122-1131 Doi: 10.1016/j.jhep.2020.01.014 [OPEN ACCESS]
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Sallinger, M; Tiffner, A; Schmidt, T; Bonhenry, D; Waldherr, L; Frischauf, I; Lunz, V; Derler, I; Schober, R; Schindl, R Luminal STIM1 Mutants that Cause Tubular Aggregate Myopathy Promote Autophagic Processes.
INT J MOL SCI. 2020; 21(12): 4410 Doi: 10.3390/ijms21124410 [OPEN ACCESS]
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Santiago-Fernández, C; Martin-Reyes, F; Tome, M; Ocaña-Wilhelmi, L; Rivas-Becerra, J; Tatzber, F; Pursch, E; Tinahones, FJ; García-Fuentes, E; Garrido-Sánchez, L Oxidized LDL Modify the Human Adipocyte Phenotype to an Insulin Resistant, Proinflamatory and Proapoptotic Profile.
BIOMOLECULES. 2020; 10(4): Doi: 10.3390/biom10040534 [OPEN ACCESS]
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Sukseree, S; Schwarze, UY; Gruber, R; Gruber, F; Quiles, Del, Rey, M; Mancias, JD; Bartlett, JD; Tschachler, E; Eckhart, L ATG7 is essential for secretion of iron from ameloblasts and normal growth of murine incisors during aging.
Autophagy. 2020; 16(10):1851-1857 Doi: 10.1080/15548627.2019.1709764 [OPEN ACCESS]
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Vidičević, S; Tošić, J; Stanojević, Ž; Isaković, A; Mitić, D; Ristić, D; Dekanski, D Standardized Olea europaea L. leaf extract exhibits protective activity in carbon tetrachloride-induced acute liver injury in rats: the insight into potential mechanisms.
Arch Physiol Biochem. 2020; 126(5): 399-407. Doi: 10.1080/13813455.2018.1550095
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2019

Baracco, EE; Castoldi, F; Durand, S; Enot, DP; Tadic, J; Kainz, K; Madeo, F; Chery, A; Izzo, V; Maiuri, MC; Pietrocola, F; Kroemer, G α-Ketoglutarate inhibits autophagy.
Aging (Albany NY). 2019; 11(11):3418-3431 Doi: 10.18632/aging.102001 [OPEN ACCESS]
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Carmona-Gutierrez, D; Zimmermann, A; Kainz, K; Pietrocola, F; Chen, G; Maglioni, S; Schiavi, A; Nah, J; Mertel, S; Beuschel, CB; Castoldi, F; Sica, V; Trausinger, G; Raml, R; Sommer, C; Schroeder, S; Hofer, SJ; Bauer, MA; Pendl, T; Tadic, J; Dammbrueck, C; Hu, Z; Ruckenstuhl, C; Eisenberg, T; Durand, S; Bossut, N; Aprahamian, F; Abdellatif, M; Sedej, S; Enot, DP; Wolinski, H; Dengjel, J; Kepp, O; Magnes, C; Sinner, F; Pieber, TR; Sadoshima, J; Ventura, N; Sigrist, SJ; Kroemer, G; Madeo, F The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species.
Nat Commun. 2019; 10(1):651-651 Doi: 10.1038/s41467-019-08555-w [OPEN ACCESS]
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Denk, H; Stumptner, C; Abuja, PM; Zatloukal, K Sequestosome 1/p62-related pathways as therapeutic targets in hepatocellular carcinoma.
Expert Opin Ther Targets. 2019; 23(5):393-406 Doi: 10.1080/14728222.2019.1601703
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Gali, CC; Fanaee-Danesh, E; Zandl-Lang, M; Albrecher, NM; Tam-Amersdorfer, C; Stracke, A; Sachdev, V; Reichmann, F; Sun, Y; Avdili, A; Reiter, M; Kratky, D; Holzer, P; Lass, A; Kandimalla, KK; Panzenboeck, U Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice.
Mol Cell Neurosci. 2019; 99: 103390-103390. Doi: 10.1016/j.mcn.2019.103390 [OPEN ACCESS]
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Gollmer, J; Zirlik, A; Bugger, H Established and Emerging Mechanisms of Diabetic Cardiomyopathy.
J Lipid Atheroscler. 2019; 8(1):26-47 Doi: 10.12997/jla.2019.8.1.26 [OPEN ACCESS]
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Gross, AS; Zimmermann, A; Pendl, T; Schroeder, S; Schoenlechner, H; Knittelfelder, O; Lamplmayr, L; Santiso, A; Aufschnaiter, A; Waltenstorfer, D; Ortonobes Lara, S; Stryeck, S; Kast, C; Ruckenstuhl, C; Hofer, SJ; Michelitsch, B; Woelflingseder, M; Müller, R; Carmona-Gutierrez, D; Madl, T; Büttner, S; Fröhlich, KU; Shevchenko, A; Eisenberg, T Acetyl-CoA carboxylase 1-dependent lipogenesis promotes autophagy downstream of AMPK.
J Biol Chem. 2019; 294(32): 12020-12039. Doi: 10.1074/jbc.RA118.007020 [OPEN ACCESS]
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Lipovšek, S; Leitinger, G; Janžekovič, F; Kozel, P; Dariš, B; Perc, M; Devetak, D; Weiland, N; Novak, T Towards understanding partial adaptation to the subterranean habitat in the European cave spider, Meta menardi: An ecocytological approach.
Sci Rep. 2019; 9(1): 9121-9121. Doi: 10.1038/s41598-019-45291-z [OPEN ACCESS]
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