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Publikationen

Suchbegriffe: SIGNAL TRANSDUCTION - PHYSIOLOGY , . Treffer: 70

2022

Galhuber, M; Michenthaler, H; Heininger, C; Reinisch, I; Nössing, C; Krstic, J; Kupper, N; Moyschewitz, E; Auer, M; Heitzer, E; Ulz, P; Birner-Gruenberger, R; Liesinger, L; Lenihan-Geels, GN; Oster, M; Spreitzer, E; Zenezini, Chiozzi, R; Schulz, TJ; Schupp, M; Madl, T; Heck, AJR; Prokesch, A Complementary omics strategies to dissect p53 signaling networks under nutrient stress.
Cell Mol Life Sci. 2022; 79(6):326 Doi: 10.1007/s00018-022-04345-8 [OPEN ACCESS]
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2019

Kukolj, T; Trivanović, D; Mojsilović, S; Okić Djordjević, I; Obradović, H; Krstić, J; Jauković, A; Bugarski, D IL-33 guides osteogenesis and increases proliferation and pluripotency marker expression in dental stem cells.
Cell Prolif. 2019; 52(1): e12533-e12533. Doi: 10.1111/cpr.12533 [OPEN ACCESS]
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2018

Groschner, K; Tiapko, O Revelation of an enigmatic signaling machinery-First insights into the mammalian TRPC architecture.
Cell Calcium. 2018; 74(9):144-146 Doi: 10.1016/j.ceca.2018.07.006
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2017

Blyszczuk, P; Müller-Edenborn, B; Valenta, T; Osto, E; Stellato, M; Behnke, S; Glatz, K; Basler, K; Lüscher, TF; Distler, O; Eriksson, U; Kania, G Transforming growth factor-β-dependent Wnt secretion controls myofibroblast formation and myocardial fibrosis progression in experimental autoimmune myocarditis.
Eur Heart J. 2017; 38(18):1413-1425 Doi: 10.1093/eurheartj/ehw116
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Buerger, C; Shirsath, N; Lang, V; Berard, A; Diehl, S; Kaufmann, R; Boehncke, WH; Wolf, P Inflammation dependent mTORC1 signaling interferes with the switch from keratinocyte proliferation to differentiation.
PLoS One. 2017; 12(7):e0180853-e0180853 Doi: 10.1371/journal.pone.0180853 [OPEN ACCESS]
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Didiasova, M; Singh, R; Wilhelm, J; Kwapiszewska, G; Wujak, L; Zakrzewicz, D; Schaefer, L; Markart, P; Seeger, W; Lauth, M; Wygrecka, M Pirfenidone exerts antifibrotic effects through inhibition of GLI transcription factors.
FASEB J. 2017; 31(5):1916-1928 Doi: 10.1096/fj.201600892RR
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2016

Lemberger, UJ; Fuchs, CD; Karer, M; Haas, S; Stojakovic, T; Schöfer, C; Marschall, HU; Wrba, F; Taketo, MM; Egger, G; Trauner, M; Österreicher, CH Hepatocyte specific expression of an oncogenic variant of β-catenin results in cholestatic liver disease.
Oncotarget. 2016; 7(52):86985-86998 Doi: 10.18632/oncotarget.13521 [OPEN ACCESS]
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Yang, Y; Liu, Y; He, JC; Wang, JM; Schemmer, P; Ma, CQ; Qian, YW; Yao, W; Zhang, J; Qi, WP; Fu, Y; Feng, W; Yang, T 14-3-3ζ and aPKC-ι synergistically facilitate epithelial-mesenchymal transition of cholangiocarcinoma via GSK-3β/Snail signaling pathway.
Oncotarget. 2016; 7(34):55191-55210 Doi: 10.18632/oncotarget.10483 [OPEN ACCESS]
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2015

Bao, Y; Ledderose, C; Graf, AF; Brix, B; Birsak, T; Lee, A; Zhang, J; Junger, WG mTOR and differential activation of mitochondria orchestrate neutrophil chemotaxis.
J Cell Biol. 2015; 210(7):1153-1164 Doi: 10.1083/jcb.201503066 [OPEN ACCESS]
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Beilfuss, A; Sowa, JP; Sydor, S; Beste, M; Bechmann, LP; Schlattjan, M; Syn, WK; Wedemeyer, I; Mathé, Z; Jochum, C; Gerken, G; Gieseler, RK; Canbay, A Vitamin D counteracts fibrogenic TGF-β signalling in human hepatic stellate cells both receptor-dependently and independently.
Gut. 2015; 64(5):791-799 Doi: 10.1136/gutjnl-2014-307024
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Doleschal, B; Primessnig, U; Wölkart, G; Wolf, S; Schernthaner, M; Lichtenegger, M; Glasnov, TN; Kappe, CO; Mayer, B; Antoons, G; Heinzel, F; Poteser, M; Groschner, K TRPC3 contributes to regulation of cardiac contractility and arrhythmogenesis by dynamic interaction with NCX1.
Cardiovasc Res. 2015; 106(1):163-173 Doi: 10.1093/cvr/cvv022 [OPEN ACCESS]
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Grabner, B; Schramek, D; Mueller, KM; Moll, HP; Svinka, J; Hoffmann, T; Bauer, E; Blaas, L; Hruschka, N; Zboray, K; Stiedl, P; Nivarthi, H; Bogner, E; Gruber, W; Mohr, T; Zwick, RH; Kenner, L; Poli, V; Aberger, F; Stoiber, D; Egger, G; Esterbauer, H; Zuber, J; Moriggl, R; Eferl, R; Győrffy, B; Penninger, JM; Popper, H; Casanova, E Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis.
Nat Commun. 2015; 6(4):6285-6285 Doi: 10.1038/ncomms7285 [OPEN ACCESS]
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2014

Alonso, N; Ralston, SH Unveiling the mysteries of the genetics of osteoporosis.
J Endocrinol Invest. 2014; 37(10): 925-34. Doi: 10.1007/s40618-014-0149-7
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Bernhart, E; Damm, S; Heffeter, P; Wintersperger, A; Asslaber, M; Frank, S; Hammer, A; Strohmaier, H; DeVaney, T; Mrfka, M; Eder, H; Windpassinger, C; Ireson, CR; Mischel, PS; Berger, W; Sattler, W Silencing of protein kinase D2 induces glioma cell senescence via p53-dependent and -independent pathways.
Neuro Oncol. 2014; 16(7):933-945 Doi: 10.1093/neuonc/not303 [OPEN ACCESS]
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Fric, J; Lim, CX; Mertes, A; Lee, BT; Viganò, E; Chen, J; Zolezzi, F; Poidinger, M; Larbi, A; Strobl, H; Zelante, T; Ricciardi-Castagnoli, P Calcium and calcineurin-NFAT signaling regulate granulocyte-monocyte progenitor cell cycle via Flt3-L.
Stem Cells. 2014; 32(12):3232-3244 Doi: 10.1002/stem.1813 [OPEN ACCESS]
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García-Rodríguez, JL; Barbier-Torres, L; Fernández-Álvarez, S; Gutiérrez-de Juan, V; Monte, MJ; Halilbasic, E; Herranz, D; Álvarez, L; Aspichueta, P; Marín, JJ; Trauner, M; Mato, JM; Serrano, M; Beraza, N; Martínez-Chantar, ML SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling.
Hepatology. 2014; 59(5):1972-1983 Doi: 10.1002/hep.26971 [OPEN ACCESS]
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Houben, R; Schmid, CP; Maier, M; Wobser, M; Motschenbacher, S; Becker, JC; Vetter-Kauczok, CS; Weyandt, G; Hesbacher, S; Haferkamp, S p53 regulation by TRP2 is not pervasive in melanoma.
PLoS One. 2014; 9(1):e87440-e87440 Doi: 10.1371/journal.pone.0087440 [OPEN ACCESS]
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Rainer, PP; Hao, S; Vanhoutte, D; Lee, DI; Koitabashi, N; Molkentin, JD; Kass, DA Cardiomyocyte-specific transforming growth factor β suppression blocks neutrophil infiltration, augments multiple cytoprotective cascades, and reduces early mortality after myocardial infarction.
Circ Res. 2014; 114(8):1246-1257 Doi: 10.1161/CIRCRESAHA.114.302653 [OPEN ACCESS]
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Szkandera, J; Pichler, M; Absenger, G; Stotz, M; Weissmueller, M; Samonigg, H; Asslaber, M; Lax, S; Leitner, G; Winder, T; Renner, W; Gerger, A A functional germline variant in GLI1 implicates hedgehog signaling in clinical outcome of stage II and III colon carcinoma patients.
Clin Cancer Res. 2014; 20(6):1687-1697 Doi: 10.1158/1078-0432.CCR-13-1517 [OPEN ACCESS]
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2013

Riehle, C; Wende, AR; Sena, S; Pires, KM; Pereira, RO; Zhu, Y; Bugger, H; Frank, D; Bevins, J; Chen, D; Perry, CN; Dong, XC; Valdez, S; Rech, M; Sheng, X; Weimer, BC; Gottlieb, RA; White, MF; Abel, ED Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
J Clin Invest. 2013; 123(12): 5319-5333. Doi: 10.1172/JCI71171 [OPEN ACCESS]
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Svejda, B; Kidd, M; Timberlake, A; Harry, K; Kazberouk, A; Schimmack, S; Lawrence, B; Pfragner, R; Modlin, IM Serotonin and the 5-HT7 receptor: the link between hepatocytes, IGF-1 and small intestinal neuroendocrine tumors.
Cancer Sci. 2013; 104(7):844-855 Doi: 10.1111/cas.12174 [OPEN ACCESS]
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Yasmin, N; Konradi, S; Eisenwort, G; Schichl, YM; Seyerl, M; Bauer, T; Stöckl, J; Strobl, H β-Catenin promotes the differentiation of epidermal Langerhans dendritic cells.
J Invest Dermatol. 2013; 133(5):1250-1259 Doi: 10.1038/jid.2012.481 [OPEN ACCESS]
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2012

Haugen, M; Dammen, R; Svejda, B; Gustafsson, BI; Pfragner, R; Modlin, I; Kidd, M Differential signal pathway activation and 5-HT function: the role of gut enterochromaffin cells as oxygen sensors.
AMER J PHYSIOL-GASTROINTEST L. 2012; 303(10): G1164-G1173. Doi: 10.1152/ajpgi.00027.2012 [OPEN ACCESS]
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2011

Aflaki, E; Radovic, B; Chandak, PG; Kolb, D; Eisenberg, T; Ring, J; Fertschai, I; Uellen, A; Wolinski, H; Kohlwein, SD; Zechner, R; Levak-Frank, S; Sattler, W; Graier, WF; Malli, R; Madeo, F; Kratky, D Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages.
J Biol Chem. 2011; 286(9): 7418-7428. Doi: 10.1074/jbc.M110.175703 [OPEN ACCESS]
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Donnerer, J; Liebmann, I A fluorescence-immunohistochemical study on phosphorylation of ERK1/2, p38, and STAT3 in rat dorsal root ganglia following noxious stimulation of hind paw sensory neurons.
Tissue Cell. 2011; 43(3): 178-189. Doi: 10.1016/j.tice.2011.02.002
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März-Weiss, P; Kunz, D; Bimmler, D; Berkemeier, C; Özbek, S; Dimitriades-Schmutz, B; Haybaeck, J; Otten, U; Graf, R Expression of pancreatitis-associated protein after traumatic brain injury: a mechanism potentially contributing to neuroprotection in human brain.
Cell Mol Neurobiol. 2011; 31(8):1141-1149 Doi: 10.1007/s10571-011-9715-0
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Matsushita, K; Cha, EK; Matsumoto, K; Baba, S; Chromecki, TF; Fajkovic, H; Sun, M; Karakiewicz, PI; Scherr, DS; Shariat, SF Immunohistochemical biomarkers for bladder cancer prognosis.
INT J UROL. 2011; 18(9): 616-629. Doi: 10.1111/j.1442-2042.2011.02809.x [OPEN ACCESS]
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2010

Damm, S; Koefinger, P; Stefan, M; Wels, C; Mehes, G; Richtig, E; Kerl, H; Otte, M; Schaider, H HGF-promoted motility in primary human melanocytes depends on CD44v6 regulated via NF-kappa B, Egr-1, and C/EBP-beta.
J Invest Dermatol. 2010; 130(7): 1893-1903. Doi: 10.1038/jid.2010.45 [OPEN ACCESS]
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Doi, T; Ruttenstock, E; Dingemann, J; Puri, P Spatiotemporal alteration in phosphatidylinositide 3-kinase-serine/threonine protein kinase B signaling in the nitrofen-induced hypoplastic lung.
J Pediatr Surg. 2010; 45(2):366-371 Doi: 10.1016/j.jpedsurg.2009.10.075
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Haas, HS; Linecker, A; Pfragner, R; Sadjak, A Peripheral glutamate signaling in head and neck areas.
Head Neck. 2010; 32(11): 1554-1572. Doi: 10.1002/hed.21438
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Kondé, E; Bourgeois, B; Tellier-Lebegue, C; Wu, W; Pérez, J; Caputo, S; Attanda, W; Gasparini, S; Charbonnier, JB; Gilquin, B; Worman, HJ; Zinn-Justin, S Structural analysis of the Smad2-MAN1 interaction that regulates transforming growth factor-β signaling at the inner nuclear membrane.
Biochemistry. 2010; 49(37):8020-8032 Doi: 10.1021/bi101153w
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Olschewski, A Targeting TASK-1 Channels as a Therapeutic Approach
ADVAN EXPERIMENT MED BIOL. 2010; 661: 459-473. Doi: 10.1007/978-1-60761-500-2_30
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Schrama, D; Kneitz, H; Willmes, C; Adam, C; Houben, R; Becker, JC Lack of correlation between IGFBP7 expression and BRAF mutational status in melanoma.
J Invest Dermatol. 2010; 130(3):897-898 Doi: 10.1038/jid.2009.304 [OPEN ACCESS]
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2009

Boudina, S; Bugger, H; Sena, S; O'Neill, BT; Zaha, VG; Ilkun, O; Wright, JJ; Mazumder, PK; Palfreyman, E; Tidwell, TJ; Theobald, H; Khalimonchuk, O; Wayment, B; Sheng, X; Rodnick, KJ; Centini, R; Chen, D; Litwin, SE; Weimer, BE; Abel, ED Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart.
Circulation. 2009; 119(9): 1272-1283. Doi: 10.1161/CIRCULATIONAHA.108.792101 [OPEN ACCESS]
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Edelsbrunner, ME; Nakano, M; Holzer, P Afferent signalling from the acid-challenged rat stomach is inhibited and gastric acid elimination is enhanced by lafutidine.
BMC Gastroenterol. 2009; 9(194): 40-40. Doi: 10.1186/1471-230X-9-40 [OPEN ACCESS]
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Schreibmayer, W Emerging role(s) of G-protein alpha-subunits in the gating of GIRKs.
J Physiol. 2009; 587(Pt 17): 4125-4126. Doi: 10.1113/jphysiol.2009.179234 [OPEN ACCESS]
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Wölfler, A; Irandoust, M; Meenhuis, A; Gits, J; Roovers, O; Touw, IP Site-specific ubiquitination determines lysosomal sorting and signal attenuation of the granulocyte colony-stimulating factor receptor.
Traffic. 2009; 10(8): 1168-1179. Doi: 10.1111/j.1600-0854.2009.00928.x [OPEN ACCESS]
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2008

Bray, MS; Shaw, CA; Moore, MW; Garcia, RA; Zanquetta, MM; Durgan, DJ; Jeong, WJ; Tsai, JY; Bugger, H; Zhang, D; Rohrwasser, A; Rennison, JH; Dyck, JR; Litwin, SE; Hardin, PE; Chow, CW; Chandler, MP; Abel, ED; Young, ME Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression.
Am J Physiol Heart Circ Physiol. 2008; 294(2): H1036-H1047. Doi: 10.1152/ajpheart.01291.2007
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Calayir, E; Becker, TM; Kratzer, A; Ebner, B; Panzenböck, U; Stefujl, J; Kostner, GM LXR-agonists regulate ApoM expression differentially in liver and intestine.
Curr Pharm Biotechnol. 2008; 9(6): 516-521. Doi: 10.2174/138920108786786376
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Gruber-Olipitz, M; Strobel, T; Chen, WQ; Grotzer, MA; Quehenberger, F; Slavc, I; Lubec, G Synthesis, chaperoning, and metabolism of proteins are regulated by NT-3/TrkC signaling in the medulloblastoma cell line DAOY.
J PROTEOME RES. 2008; 7(5): 1932-1944. Doi: 10.1021/pr700724a
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Jacobshagen, C; Grüber, M; Teucher, N; Schmidt, AG; Unsöld, BW; Toischer, K; Nguyen, VP; Maier, LS; Kögler, H; Hasenfuss, G Celecoxib modulates hypertrophic signalling and prevents load-induced cardiac dysfunction.
Eur J Heart Fail. 2008; 10(4): 334-342. Doi: 10.1016/j.ejheart.2008.02.013 [OPEN ACCESS]
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Rauh, A; Windischhofer, W; Kovacevic, A; DeVaney, T; Huber, E; Semlitsch, M; Leis, HJ; Sattler, W; Malle, E Endothelin (ET)-1 and ET-3 promote expression of c-fos and c-jun in human choriocarcinoma via ET(B) receptor-mediated G(i)- and G(q)-pathways and MAP kinase activation.
Br J Pharmacol. 2008; 154(1):13-24 Doi: 10.1038/bjp.2008.92 [OPEN ACCESS]
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Shawcross, DL; Wright, GA; Stadlbauer, V; Hodges, SJ; Davies, NA; Wheeler-Jones, C; Pitsillides, AA; Jalan, R Ammonia impairs neutrophil phagocytic function in liver disease.
Hepatology. 2008; 48(4): 1202-1212. Doi: 10.1002/hep.22474 [OPEN ACCESS]
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2007

Eder, P; Poteser, M; Groschner, K TRPC3: a multifunctional, pore-forming signalling molecule.
Handb Exp Pharmacol. 2007; 77-92 Doi: 10.1007/978-3-540-34891-7_4
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Eder, P; Probst, D; Rosker, C; Poteser, M; Wolinski, H; Kohlwein, SD; Romanin, C; Groschner, K Phospholipase C-dependent control of cardiac calcium homeostasis involves a TRPC3-NCX1 signaling complex.
Cardiovasc Res. 2007; 73(1): 111-119. Doi: 10.1016/j.cardiores.2006.10.016 [OPEN ACCESS]
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Haxhija, EQ; Yang, H; Spencer, AU; Sun, X; Teitelbaum, DH Intestinal epithelial cell proliferation is dependent on the site of massive small bowel resection.
Pediatr Surg Int. 2007; 23(5): 379-390. Doi: 10.1007/s00383-006-1855-9
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Hesse, M; Fröhlich, LF; Zeitz, U; Lanske, B; Erben, RG Ablation of vitamin D signaling rescues bone, mineral, and glucose homeostasis in Fgf-23 deficient mice.
Matrix Biol. 2007; 26(2): 75-84. Doi: 10.1016/j.matbio.2006.10.003
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Jost, PJ; Ruland, J Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications.
Blood. 2007; 109(7):2700-2707 Doi: 10.1182/blood-2006-07-025809
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Staber, PB; Vesely, P; Haq, N; Ott, RG; Funato, K; Bambach, I; Fuchs, C; Schauer, S; Linkesch, W; Hrzenjak, A; Dirks, WG; Sexl, V; Bergler, H; Kadin, ME; Sternberg, DW; Kenner, L; Hoefler, G The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling.
Blood. 2007; 110(9):3374-3383 Doi: 10.1182/blood-2007-02-071258 [OPEN ACCESS]
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2005

Eder, P; Poteser, M; Romanin, C; Groschner, K Na(+) entry and modulation of Na(+)/Ca(2+) exchange as a key mechanism of TRPC signaling.
Pflugers Arch. 2005; 451(1):99-104 Doi: 10.1007/s00424-005-1434-2
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