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Stranzl, H; Zurl, B; Langsenlehner, T; Kapp, KS.
Wide tangential fields including the internal mammary lymph nodes in patients with left-sided breast cancer. Influence of respiratory-controlled radiotherapy (4D-CT) on cardiac exposure.
Strahlenther Onkol. 2009; 185(3):155-160 Doi: 10.1007/s00066-009-1939-2
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Führende Autor*innen der Med Uni Graz

Stranzl-Lawatsch Heidi

Co-Autor*innen der Med Uni Graz

Kapp Karin S.

Langsenlehner Tanja

Zurl Brigitte

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Abstract:

To evaluate the impact of wide-tangent fields including the internal mammary chain during deep inspiration breath-hold (DIBH) radiotherapy in patients with left-sided breast cancer on cardiac exposure. Eleven patients with left-sided breast cancer were irradiated postoperatively and underwent CT scans during free breathing and DIBH. For scientific interest only, treatment plans were calculated consisting of wide tangents including the ipsilateral mammary lymph nodes using both, the free breathing and respiratory-controlled CT scan. The resulting dose-volume histograms were compared for irradiated volumes and doses to organs at risk. The mean patient age was 51 years (range: 37-65 years). Radiotherapy using wide tangents with DIBH as compared to free breathing led to a significantly lower cardiac exposure. Mean irradiated heart volumes (> or = 20 Gy) were 14 cm(3) (range: 0-51.3 cm(3)) versus 35 cm(3) (range: 2.1-78.7 cm(3); p = 0.01). For eight patients, DIBH reduced irradiated relative lung volume, while in three patients, the lung volume slightly increased. Radiation exposure of organs at risk can significantly be reduced for breast cancer patients using the DIBH technique. If radiotherapy of the internal mammary lymph nodes is considered necessary, DIBH may be the preferable technique.

Find related publications in this database (using NLM MeSH Indexing)

Adult -

Aged -

Body Burden -

Breast Neoplasms - diagnostic imaging

Breast Neoplasms - radiotherapy

Female -

Heart - radiation effects

Humans -

Lymph Nodes - diagnostic imaging

Lymph Nodes - radiation effects

Lymphatic Metastasis -

Middle Aged -

Motion -

Radiation Dosage -

Radiation Protection - methods

Radiography -

Relative Biological Effectiveness -

Respiratory Mechanics -

Respiratory-Gated Imaging Techniques - methods

Treatment Outcome -

Find related publications in this database (Keywords)

Left-sided breast carcinoma

Deep inspiration breath-hold technique

Internal mammary chain

Organs at risk

Wide tangents

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