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SHR Neuro Cancer Cardio Lipid Metab Microb

Navarrete-Dechent, C; Longo, C; Liopyris, K; Ardigo, M; Ahlgrimm-Siess, V; Bahadoran, P; Carrera, C; Tavoloni, Braga, JC; Chen, CJ; Correa, L; de, Carvahlo, N; Durkin, J; Farnetani, F; Grant-Kels, JM; Gill, M; Gonzalez, S; Hartmann, D; Hoffman-Wellenhof, R; Huho, A; Ludzik, J; Malvehy, J; Marghoob, AA; Moscarella, E; Oliviero, M; Puig, S; Rabinovitz, H; Rao, B; Rezze, GG; Rossi, AM; Rubinstein, G; Ruini, C; Sattler, E; Soyer, HP; Schwartz, R; Thng, S; Ulrich, M; Witkowski, A; Dusza, SW; Guitera, P; Pellacani, G; Scope, A; Jain, M.
Reflectance confocal microscopy terminology for non-melanocytic skin lesions: A Delphi consensus of experts.
J Am Acad Dermatol. 2025; Doi: 10.1016/j.jaad.2025.05.1362
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Co-authors Med Uni Graz
Ahlgrimm-Siess Verena
Soyer Hans Peter
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Abstract:
BACKGROUND: There is lack of uniformity in reflectance confocal microscopy (RCM) terminology. OBJECTIVE: To establish expert consensus on a standardized set of RCM terms that describe non-melanocytic lesions (NML). METHODS: We invited RCM experts to participate in a Delphi-consensus study. Fifty-nine RCM descriptors were extracted from a previous systematic review on RCM terminology for describing NML. Of these, 35 items were presented as 4 groups of synonymous terms and 24 items as single, non-synonymous terms. For the first round, an agreement threshold was set at >70%. Participants could also propose new terms. Terms with ≤70% agreement and newly proposed terms were carried over to the next round. For subsequent rounds, agreement threshold was set at >50%. RESULTS: The study was conducted between June 2021 and May 2023. Forty-two of 44 (95%) invited experts participated. Three iterative Delphi rounds were completed, resulting in a consensus list of 36 terms, including 32 synonymous- and 4 non-synonymous- terms for describing NML. LIMITATIONS: Only experts were included. We did not evaluate definitions of terms in the study. CONCLUSIONS: We propose a simplified list of RCM terms, vetted by RCM experts, for describing and diagnosing NML. Uniform terminology could benefit clinical practice, research, and education.

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