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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Winkler, D; Hammer, N; Oehlwein, C; Schwarz, J; Strecker, K; Fritzsch, D; Meixensberger, J.
Implementing conventional Zamorano Dujovny frames versus individually manufactured microTargeting platforms--a comparative study on deep brain stimulation in Parkinson patients.
Stereotact Funct Neurosurg. 2013; 91(6):392-398
Doi: 10.1159/000351522
Web of Science
PubMed
FullText
FullText_MUG
- Co-authors Med Uni Graz
- Hammer Niels
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- Abstract:
- Individually manufactured microTargeting™ platforms (MT) provide a novel generation of stereotactic systems based on preoperatively implanted bone markers and screws. The feasibility and reliability of these frames were evaluated for bilateral deep brain stimulation (DBS) in patients with idiopathic Parkinson's disease (IPD). Surgical and clinical results were compared to conventional Zamorano Dujovny frames (ZD) in this prospective study. Twenty-six IPD patients undergoing surgery for DBS were divided into 2 groups. In group I, electrode implantation was accomplished using conventional ZD. Group II underwent electrode implantation using MT. Microrecording and macrostimulation were performed and surgery time was measured. The clinical outcome was determined using the Unified Parkinson's Disease Rating Scale Part III (UPDRS III) and L-dopa-equivalent doses for a 12-month follow-up postoperatively. Clinical evaluation confirmed comparable outcomes for both targeting procedures and electrode positioning. Surgical time was lower in group II than in group I. Significant improvements were determined for both groups in UPDRS III and L-dopa-equivalent dose. Both systems allow for reliable and safe neurosurgical procedures, yielding comparable clinical results. MT improved handling and automatic adjustment of frame coordinates. Surgery time was reduced markedly compared to conventional frames.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Deep Brain Stimulation - instrumentation
- Deep Brain Stimulation - methods
- Female -
- Humans -
- Male -
- Middle Aged -
- Parkinson Disease - physiopathology
- Parkinson Disease - therapy
- Prospective Studies -
- Reproducibility of Results -
- Severity of Illness Index -
- Stereotaxic Techniques - instrumentation
- Subthalamic Nucleus - physiopathology
- Treatment Outcome -
- Find related publications in this database (Keywords)
- Deep brain stimulation
- Idiopathic Parkinson disease
- STarFix microTargeting (TM) platform
- Stereotaxy
- Subthalamic nucleus