Medizinische Universität Graz - Research portal
Selected Publication:
Krachler, M; Prohaska, T; Koellensperger, G; Rossipal, E; Stingeder, G.
Concentrations of selected trace elements in human milk and in infant formulas determined by magnetic sector field inductively coupled plasma-mass spectrometry.
Biol Trace Elem Res. 2000; 76(2):97-112
Doi: 10.1385/BTER:76:2:97
Web of Science
PubMed
FullText
FullText_MUG
- Authors Med Uni Graz:
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Magnetic sector field inductively coupled plasma-mass spectrometry (ICP-MS) was applied to the reliable determination of the 8 essential trace elements cobalt (Co), chromium (Cr), copper (Cu), iron (Fe), manganese (Mn), nickel (Ni), selenium (Se), and vanadium (V) as well as the 7 nonessential and toxic elements silver (Ag), aluminum (Al), arsenic (As), gold (Au), platinum (Pt), scandium (Sc), and titanum (Ti) in 27 transitory and mature human milk samples and in 4 selected infant formulas. This advanced instrumentation can separate spectral overlaps from the analyte signal hampering significantly the determination of many trace elements by conventional ICP-MS. Moreover, superior detection limits in the picogram per liter range can be obtained with such magnetic sector field instruments. Therefore, this is the first study to report, the concentrations of the elements Ag, Au, Pt, Sc, Ti, and V in human milk and in infant formulas. Concentrations of Ag (median: 0.41 microg/L; range: < 0.13-42 microg/L) and Au (median: 0.29 microg/L; range 0.10-2.06 microg/L) showed large variations in human milk that might be associated with dental fillings and jewelry. Pt concentrations were very low with most of the samples below the method detection limit of 0.01 microg/L. Human milk concentrations of Co (median: 0.19 microg/L), Fe (380 microg/L), Mn (6.3 microg/L), Ni (0.79 microg/L), and Se (17 microg/L) were at the low end of the corresponding reference ranges. Concentrations of Cr (24.3 microg/L) in human milk were five times higher than the high end of the reference range. For Al (67 microg/L), As (6.7 microg/L), and V (0.18 microg/L), most of the samples had concentrations well within the reference ranges. All elemental concentrations in infant formulas (except for Cr) were approximately one order of magnitude higher than in human milk.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Austria -
- Calibration -
- Female -
- Humans -
- Indicators and Reagents -
- Infant -
- Infant Food - analysis
- Mass Spectrometry - analysis
- Milk, Human - chemistry
- Quality Control - chemistry
- Reference Values - chemistry
- Trace Elements - analysis
- Find related publications in this database (Keywords)
- human milk
- formulas
- trace elements
- inductively coupled plasma-mass spectrometry
- high resolution
- interferences